Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Hernández-Aguado JJ, de La Fuente-Valero J, Ramírez Mena M, Ortega-Medina L, Vidart Aragón JA, Galán JC.

    Comparative pilot study about HPV test with partial genotyping in primary screening versus other strategies for cervical cancer population screening, CRYGEN 16/18 study.

    Enfermedades Infecciosas Y Microbiologia Clinica (english Ed.) . : .

    [doi:10.1016/j.eimce.2022.08.001]

  • Canton R, Doi Y, Simner PJ.

    Treatment of carbapenem-resistant Pseudomonas aeruginosa infections: a case for cefiderocol.

    EXPERT REVIEW OF ANTI-INFECTIVE THERAPY . 20(8): 1-18. Number of citations: 1

    [doi:10.1080/14787210.2022.2071701]

  • Hernández-Sampelayo T, Gómez-Pavón J, González Del Castillo J, Martín-Delgado MC, Martín Sánchez FJ, Martínez-Sellés M, Molero García JM, Moreno Guillén S, Rodríguez-Artalejo FJ, Ruiz-Galiana J, Cantón R, De Lucas Ramos P, García-Botella A, García-Lledó A, Calvo Rey P, Bouza E.

    COVID in Pediatric Age: an opinion paper.

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 35(4): 333-343. Number of citations: 1

    [doi:10.37201/req/012.2022]

  • Hernández-García M, García-Castillo M, Bou G, Cercenado E, Delgado-Valverde M, Oliver A, Pitart C, Rodríguez-Lozano J, Tormo N, Melo-Cristino J, Pinto MF, Gonçalves E, Alves V, Vieira AR, Ramalheira E, Sancho L, Diogo J, Ferreira R, Cruz H, Chaves C, Duarte J, Pássaro L, Díaz-Regañón J, Cantón R.

    Imipenem-Relebactam Susceptibility in Enterobacterales Isolates Recovered from ICU Patients from Spain and Portugal (SUPERIOR and STEP Studies)

    Microbiology spectrum . : . Number of citations: 6

    [doi:10.1128/spectrum.02927-22]

  • Martins-Oliveira I, Pérez-Viso B, Silva-Dias A, Gomes R, Peixe L, Novais Â, Cantón R, Pina-Vaz C.

    Rapid Detection of Plasmid AmpC Beta-Lactamases by a Flow Cytometry Assay

    ANTIBIOTICS-BASEL . 11(8): .

    [doi:10.3390/antibiotics11081130]

  • Fluit AC, Bayjanov JR, Benaissa-Trouw BJ, Rogers MRC, Díez-Aguilar M, Cantón R, Tunney MM, Elborn JS, Ekkelenkamp MB.

    Whole-genome analysis of Haemophilus influenzae strains isolated from persons with cystic fibrosis.

    JOURNAL OF MEDICAL MICROBIOLOGY . 71(8): .

    [doi:10.1099/jmm.0.001570]

  • Trastoy R, Gonzalez-Alba JM, Soriano V, Rodriguez-Calviño JJ, de Mendoza C, Costa JJ, Cea M, Barbeito G, Corral O, Gómez-Gallego F, Pérez Del Molino ML, Carlos Galán J, Aguilera A.

    The unexpected high prevalence of HBV subgenotype D4 in patients with chronic hepatitis B in Galicia, a northwestern Spanish region, reflects strong links with Latin America

    JOURNAL OF CLINICAL VIROLOGY . 153: 105195-105195.

    [doi:10.1016/j.jcv.2022.105195]

  • Casado JL, Vizcarra P, Haemmerle J, Velasco H, Martín-Hondarza A, Rodríguez-Domínguez MJ, Velasco T, Martín S, Romero-Hernández B, Fernández-Escribano M, Vallejo A.

    Pre-existing T cell immunity determines the frequency and magnitude of cellular immune response to two doses of mRNA vaccine against SARS-CoV-2.

    Vaccine: X . 11: 100165-100165. Number of citations: 3

    [doi:10.1016/j.jvacx.2022.100165]

  • Romero-Hernández B, Martínez-García L, Rodríguez-Dominguez M, Martínez-Sanz J, Vélez-Díaz-Pallarés M, Pérez Mies B, Muriel A, Gea F, Pérez-Elías MJ, Galán JC.

    The Negative Impact of COVID-19 in HCV, HIV, and HPV Surveillance Programs During the Different Pandemic Waves.

    Frontiers in Public Health . 10: 880435-880435. Number of citations: 1

    [doi:10.3389/fpubh.2022.880435]

  • Troyano-Hernáez P, Reinosa R, Holguín A.

    Genetic Diversity and Low Therapeutic Impact of Variant-Specific Markers in HIV-1 Pol Proteins.

    FRONTIERS IN MICROBIOLOGY . 13: 866705-866705.

    [doi:10.3389/fmicb.2022.866705]

  • Pereira, Ana P., Antunes, Patricia, Willems, Rob, Corander, Jukka, Coque, Teresa M., Peixe, Luisa, Freitas, Ana R., Novais, Carla.

    Evolution of Chlorhexidine Susceptibility and of the EfrEF Operon among Enterococcus faecalis from Diverse Environments, Clones, and Time Spans

    Microbiology spectrum . 10(4): .

    [doi:10.1128/spectrum.01176-22]

  • Jiménez D, Martínez-Sanz J, Sainz T, Calvo C, Méndez-Echevarría A, Moreno E, Blázquez-Gamero D, Vizcarra P, Rodríguez M, Jenkins R, Sánchez-Conde M, Ron R, Norman F, Moreno S, Ferrer M, Serrano-Villar S.

    Differences in saliva ACE2 activity among infected and non-infected adult and pediatric population exposed to SARS-CoV-2.

    JOURNAL OF INFECTION . 85(1): 86-89.

    [doi:10.1016/j.jinf.2022.04.041]

  • Cañada-García JE, Moure Z, Sola-Campoy PJ, Delgado-Valverde M, Cano ME, Gijón D, González M, Gracia-Ahufinger I, Larrosa N, Mulet X, Pitart C, Rivera A, Bou G, Calvo J, Cantón R, González-López JJ, Martínez-Martínez L, Navarro F, Oliver A, Palacios-Baena ZR, Pascual Á, Ruiz-Carrascoso G, Vila J, Aracil B, Pérez-Vázquez M, Oteo-Iglesias J.

    CARB-ES-19 Multicenter Study of Carbapenemase-Producing Klebsiella pneumoniae and Escherichia coli From All Spanish Provinces Reveals Interregional Spread of High-Risk Clones Such as ST307/OXA-48 and ST512/KPC-3

    FRONTIERS IN MICROBIOLOGY . 13: 918362-918362. Number of citations: 10

    [doi:10.3389/fmicb.2022.918362]

  • Fuchs F, Becerra-Aparicio F, Xanthopoulou K, Seifert H, Higgins PG.

    In vitro activity of nitroxoline against carbapenem-resistant Acinetobacter baumannii isolated from the urinary tract.

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 77(7): 1912-1915. Number of citations: 3

    [doi:10.1093/jac/dkac123]

  • Saralegui C, Herencias C, Halperin AV, de Dios-Caballero J, Pérez-Viso B, Salgado S, Lanza VF, Cantón R, Baquero F, Prieto MA, del Campo R.

    Strain-specific predation of Bdellovibrio bacteriovorus on Pseudomonas aeruginosa with a higher range for cystic fibrosis than for bacteremia isolates.

    SCIENTIFIC REPORTS . 12(1): 10523-10523. Number of citations: 3

    [doi:10.1038/s41598-022-14378-5]

  • Muñoz-Chimeno M, Bartúren S, García-Lugo MA, Morago L, Rodríguez Á, Galán JC, Pérez-Rivilla A, Rodríguez M, Millán R, Del Álamo M, Alonso R, Molina L, Aguinaga A, Avellón A.

    Hepatitis E virus genotype 3 microbiological surveillance by the Spanish Reference Laboratory: geographic distribution and phylogenetic analysis of subtypes from 2009 to 2019

    Eurosurveillance . 27(23): . Number of citations: 12

    [doi:10.2807/1560-7917.ES.2022.27.23.2100542]

  • Troyano-Hernáez P, Reinosa R, Holguín Á.

    Evolution of SARS-CoV-2 in Spain during the First Two Years of the Pandemic: Circulating Variants, Amino Acid Conservation, and Genetic Variability in Structural, Non-Structural, and Accessory Proteins.

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 23(12): . Number of citations: 6

    [doi:10.3390/ijms23126394]

  • Feito, Javier, Araujo, Carlos, Gomez-Sala, Beatriz, Contente, Diogo, Campanero, Cristina, Arbulu, Sara, Saralegui, Claudia, Pena, Nuria, Munoz-Atienza, Estefania, Borrero, Juan, del Campo, Rosa, Hernandaz, Pablo E., Cintas, Luis M..

    Antimicrobial activity, molecular typing and in vitro safety assessment of Lactococcus garvieae isolates from healthy cultured rainbow trout (Oncorhynchus mykiss, Walbaum) and rearing environment

    LWT-FOOD SCIENCE AND TECHNOLOGY . 162: . Number of citations: 1

    [doi:10.1016/j.lwt.2022.113496]