Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Casado JL, Vizcarra P, del Rey JM, Soriano MC, Rodriguez-Dominguez M, Manzano L, Acero J, Palomar-Fernandez C, Vallejo A, On Behalf Of The Covid-Irycis Team.

    Lost in Translation: Evaluation of Subcutaneous Interferon-ß Treatment for SARS-CoV-2 Infection in Real Life

    Journal Of Clinical Medicine . 11(23): .

    [doi:10.3390/jcm11236952]

  • Ventosa-Cubillo J, Pinzón R, González-Alba JM, Estripeaut D, Navarro ML, Holguín Á.

    Drug resistance in children and adolescents with HIV in Panama.

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 78(2): 423-435.

    [doi:10.1093/jac/dkac407]

  • DelaFuente J, Toribio-Celestino L, Santos-Lopez A, León-Sampedro R, Alonso-Del Valle A, Costas C, Hernández-García M, Cui L, Rodríguez-Beltrán J, Bikard D, Cantón R, San Millan A.

    Within-patient evolution of plasmid-mediated antimicrobial resistance

    Nature Ecology & Evolution . 6(12): 1980. Number of citations: 9

    [doi:10.1038/s41559-022-01908-7]

  • López JN, Prieto-Tato L, Escosa L, Bernardino JI, Muñoz E, Díez C, Carrasco I, Ryan P, Guillén-Martín S, Ramos Amador JT, Navarro ML, Holguín A, Sainz T.

    Pregnancy Outcomes Among Perinatally HIV-infected women in Spain.

    JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES . 91(4): 373-380.

    [doi:10.1097/QAI.0000000000003070]

  • Navarrete-Muñoz MA, Ramos R, Holguín Á, Cabello A, Górgolas M, Benito JM, Rallón N.

    High frequency of CD8 escape mutations in elite controllers as new obstacle for HIV cure.

    Virulence . 13(1): 1713-1719.

    [doi:10.1080/21505594.2022.2129353]

  • Baquero F, Coque TM, Martínez JL.

    Natural detoxification of antibiotics in the environment: A one health perspective

    FRONTIERS IN MICROBIOLOGY . 13: 1062399-1062399. Number of citations: 3

    [doi:10.3389/fmicb.2022.1062399]

  • López-Causapé C, Maruri-Aransolo A, Gomis-Font MA, Penev I, Castillo MG, Mulet X, de Dios Caballero J, Campo RD, Cantón R, Oliver A.

    Cefiderocol resistance genomics in sequential chronic Pseudomonas aeruginosa isolates from cystic fibrosis patients.

    CLINICAL MICROBIOLOGY AND INFECTION . 29(4): . Number of citations: 2

    [doi:10.1016/j.cmi.2022.11.014]

  • Pérez-Mies B, Caniego-Casas T, Bardi T, Carretero-Barrio I, Benito A, García-Cosío M, González-García I, Pizarro D, Rosas M, Cristóbal E, Ruano Y, Garrido MC, Rigual-Bobillo J, de Pablo R, Galán JC, Pestaña D, Palacios J.

    Progression to lung fibrosis in severe COVID-19 patients: A morphological and transcriptomic study in postmortem samples

    Frontiers In Medicine . 9: 976759-976759. Number of citations: 3

    [doi:10.3389/fmed.2022.976759]

  • Vivancos-Gallego MJ, Sánchez-Conde M, Rodríguez-Domínguez M, Fernandez-Gonzalez P, Martínez-García L, Garcia-Mouronte E, Martínez-Sanz J, Moreno-Zamora AM, Casado JL, Ron R, Galán JC, Pérez-Elías MJ, Moreno S.

    Human Monkeypox in People With HIV: Transmission, Clinical Features, and Outcome

    Open forum infectious diseases . 9(11): . Number of citations: 10

    [doi:10.1093/ofid/ofac557]

  • Díaz-García J, Gómez A, Machado M, Alcalá L, Reigadas E, Sánchez-Carrillo C, Pérez-Ayala A, de la Pedrosa EG, González-Romo F, Cuétara MS, García-Esteban C, Quiles-Melero I, Zurita ND, Algarra MM, Durán-Valle MT, Sánchez-García A, Muñoz P, Escribano P, Guinea J, On Behalf Of The Candimad Study Group.

    Candida Genotyping of Blood Culture Isolates from Patients Admitted to 16 Hospitals in Madrid: Genotype Spreading during the COVID-19 Pandemic Driven by Fluconazole-Resistant C. parapsilosis

    JOURNAL OF FUNGI . 8(11): . Number of citations: 6

    [doi:10.3390/jof8111228]

  • Drevinek P, Canton R, Johansen HK, Hoffman L, Coenye T, Burgel PR, Davies JC.

    New concepts in antimicrobial resistance in cystic fibrosis respiratory infections

    JOURNAL OF CYSTIC FIBROSIS . 21(6): 937-945. Number of citations: 6

    [doi:10.1016/j.jcf.2022.10.005]

  • Moraleda C, Domínguez-Rodríguez S, Mesa JM, García-Sánchez P, de la Serna M, Alonso-Cadenas JA, Bermejo A, Sabrido G, Martínez-Campos L, González-Posada AF, Illán-Ramos M, Cobos-Carrascosa E, Ballesteros Á, Galán JC, Llorente F, Aguilera-Alonso D, Jiménez AB, Catalán P, Dahdouh E, Navarro I, Fernández-Garoz B, Mendoza P, Pérez-Jorge C, Cabezas-Fernández T, Blázquez-Gamero D, Rivas G, Gonzalez-Donapetry P, Sáez E, Fernández-Pinero J, Lucas-Fernández J, Pérez-Ramírez E, Merino P, Miragaya S, Lorente J, Iglesias I, Tagarro A.

    Oral saliva swab reverse transcription PCR for Covid-19 in the paediatric population

    ARCHIVES OF DISEASE IN CHILDHOOD . 107(11): 1051-1058. Number of citations: 2

    [doi:10.1136/archdischild-2021-323712]

  • Hernández-García M, García-Castillo M, Melo-Cristino J, Pinto MF, Gonçalves E, Alves V, Vieira AR, Ramalheira E, Sancho L, Diogo J, Ferreira R, Cruz H, Chaves C, Bou G, Cercenado E, Delgado-Valverde M, Oliver A, Pitart C, Rodríguez-Lozano J, Tormo N, Díaz-Regañón J, Pássaro L, Duarte J, Cantón R.

    In vitro activity of imipenem/relebactam against Pseudomonas aeruginosa isolates recovered from ICU patients in Spain and Portugal (SUPERIOR and STEP studies)

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 77(11): 3163-3172. Number of citations: 5

    [doi:10.1093/jac/dkac298]

  • Díaz-García J, Gómez A, Machado M, Alcalá L, Reigadas E, Sánchez-Carrillo C, Pérez-Ayala A, Gómez-García de la Pedrosa E, González-Romo F, Cuétara MS, García-Esteban C, Quiles-Melero I, Zurita ND, Muñoz-Algarra M, Durán-Valle MT, Sánchez-García A, Muñoz P, Escribano P, Guinea J.

    Blood and intra-abdominal Candida spp. from a multicentre study conducted in Madrid using EUCAST: emergence of fluconazole resistance in Candida parapsilosis, low echinocandin resistance and absence of Candida auris

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 77(11): 3102-3109. Number of citations: 11

    [doi:10.1093/jac/dkac288]

  • Pedraza R, Kieffer N, Guzmán-Puche J, Artacho MJ, Pitart C, Hernández-García M, Vila J, Cantón R, Martinez-Martinez L.

    Hidden dissemination of carbapenem-susceptible OXA-48-producing Proteus mirabilis.

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 77(11): 3009-3015.

    [doi:10.1093/jac/dkac267]

  • Pina-Coronado C, Martínez-Sobrino Á, Gutiérrez-Gálvez L, Del Caño R, Martínez-Periñán E, García-Nieto D, Rodríguez-Peña M, Luna M, Milán-Rois P, Castellanos M, Abreu M, Cantón R, Galán JC, Pineda T, Pariente F, Somoza Á, García-Mendiola T, Miranda R, Lorenzo E.

    Methylene Blue functionalized carbon nanodots combined with different shape gold nanostructures for sensitive and selective SARS-CoV-2 sensing

    SENSORS AND ACTUATORS B-CHEMICAL . 369: 132217-132217. Number of citations: 8

    [doi:10.1016/j.snb.2022.132217]

  • Gijón Cordero D, Castillo-Polo JA, Ruiz-Garbajosa P, Cantón R.

    Antibacterial spectrum of cefiderocol.

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 35 Suppl 2: 20-27. Number of citations: 2

    [doi:10.37201/req/s02.03.2022]

  • Ferrer R, Soriano A, Cantón R, Del Pozo JL, García-Vidal C, Garnacho-Montero J, Larrosa N, Rascado P, Salavert M, Pintado V, Giró-Perafita N, Badia X.

    A systematic literature review and expert consensus on risk factors associated to infection progression in adult patients with respiratory tract or rectal colonisation by carbapenem-resistant Gram-negative bacteria.

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 35(5): 455-467. Number of citations: 3

    [doi:10.37201/req/062.2022]