Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Imagen equipo

Group leaders

Rafael Cantón Moreno

Patricia Ruiz Garbajosa

rafael.canton(ELIMINAR)@salud.madrid.org

Tlf.: +34 91 3367031

Principal Investigator

  • María Teresa Coque González
  • Juan Carlos Galán Montemayor
  • África Holguín Fernández
  • Fernando Baquero Mochales
  • Jerónimo Carlos Rodríguez Beltrán
  • Juan de Dios Caballero Pérez
  • Ana Elena Perez Cobas
  • Cristina Herencias Rodríguez
  • Marta Hernández García
  • Joao Pedro Alves Gama

Collaborating Staff

  • María Elia Gómez García de la Pedrosa
  • Mario José Rodríguez Domínguez
  • Marta Tato Díez
  • María del Carmen García Castillo
  • Laura Martínez García
  • Blanca Pérez Viso
  • María Elena Martínez Rodríguez
  • Carmen de la Vega Losada
  • Ana Verónica Halperín
  • Desirée Gijón Cordero
  • Ainhize Maruri Aransolo
  • Beatriz Romero Hernández
  • Pedro Manuel Ponce Alonso
  • Ana Fernández Olmos
  • Natalia Guerra Pinto
  • Silvia Serrano Calleja
  • Paula Ramiro Martinez
  • Carolina López López
  • Laura Jaraba Soto
  • Luna Ballestero García
  • Judit Maria Ventosa Cubillo
  • Marina Dominguez Gaitero
  • Laura Alvaro Llorente
  • Paloma Tage Troyano Hernáez
  • Roberto Reinosa Fernández
  • Mario Herbert Romero Rivera
  • María Asunción Garriga García
  • Esther Palacios Gómez
  • Ada Muñoz Cazalla
  • Carlos Medina Sánchez
  • Ainoa Paredes Plaza
  • Leticia Gomez Artiguez
  • Luis Fuertes Pina
  • Astrid Henrich Gutierrez
  • Paula Escorial García
  • Claudia Sanz González
  • Iván Linares Ambohades
  • Verónica Ventosa Cubillo
  • Ignacio de Quinto Cáceres
  • Manuel Domínguez Pino
  • Esther Serrano-Conde Sánchez
  • Sandra Mingo Ramirez
Imagen equipo

Group leaders

Rafael Cantón Moreno

Patricia Ruiz Garbajosa

rafael.canton(ELIMINAR)@salud.madrid.org

Tlf.: +34 91 3367031

Principal Investigator

  • María Teresa Coque González
  • Juan Carlos Galán Montemayor
  • África Holguín Fernández
  • Fernando Baquero Mochales
  • Jerónimo Carlos Rodríguez Beltrán
  • Juan de Dios Caballero Pérez
  • Ana Elena Perez Cobas
  • Cristina Herencias Rodríguez
  • Marta Hernández García
  • Joao Pedro Alves Gama

Collaborating Staff

  • María Elia Gómez García de la Pedrosa
  • Mario José Rodríguez Domínguez
  • Marta Tato Díez
  • María del Carmen García Castillo
  • Laura Martínez García
  • Blanca Pérez Viso
  • María Elena Martínez Rodríguez
  • Carmen de la Vega Losada
  • Ana Verónica Halperín
  • Desirée Gijón Cordero
  • Ainhize Maruri Aransolo
  • Beatriz Romero Hernández
  • Pedro Manuel Ponce Alonso
  • Ana Fernández Olmos
  • Natalia Guerra Pinto
  • Silvia Serrano Calleja
  • Paula Ramiro Martinez
  • Carolina López López
  • Laura Jaraba Soto
  • Luna Ballestero García
  • Judit Maria Ventosa Cubillo
  • Marina Dominguez Gaitero
  • Laura Alvaro Llorente
  • Paloma Tage Troyano Hernáez
  • Roberto Reinosa Fernández
  • Mario Herbert Romero Rivera
  • María Asunción Garriga García
  • Esther Palacios Gómez
  • Ada Muñoz Cazalla
  • Carlos Medina Sánchez
  • Ainoa Paredes Plaza
  • Leticia Gomez Artiguez
  • Luis Fuertes Pina
  • Astrid Henrich Gutierrez
  • Paula Escorial García
  • Claudia Sanz González
  • Iván Linares Ambohades
  • Verónica Ventosa Cubillo
  • Ignacio de Quinto Cáceres
  • Manuel Domínguez Pino
  • Esther Serrano-Conde Sánchez
  • Sandra Mingo Ramirez

STRATEGIC OBJECTIVES

  • Innovation and development in translational microbiology research, with an emphasis on the anthropogenic influence on the emergence and spread of pathogenic and/or antimicrobial-resistant microorganisms and potential control strategies.
  • Consolidation of molecular microbiology techniques, bioinformatics platforms, and mathematical and computational modeling for studying changes in microbial biology and the microbiome that influence human health, considered at multiple hierarchical levels (from genes to clones to patients and the built environment).
  • Consolidation of innovative and useful microbiology for public health, based in the hospital, with applications in hospital-acquired infections, but also in community-acquired infections and environmental microbial ecosystems.
  • Training of researchers in molecular microbiology and public health microbiology.

RESEARCH LINES

  • Epidemiology of antibiotic resistance, clinical trials of diagnostic tests and phage therapy (PI: Dr. R. Cantón, Co-PI: Dr. P. Ruiz-Garbajosa, Dr. M. Hernández)
  • Evolutionary microbiology, eco-microbiology and modeling of microbial processes with relevance to global health (PI: Dr. F. Baquero; Co-PI: Dr. J. Alves Gama)
  • Biology of bacterial populations, mobile genetic elements and resistome (PI: Dr. M.T. Coque, Co-PI: Dr. AE. Pérez Cobas)
  • Metagenomics/Microbiome and disease; Host-parasite interaction (PI: Dr. R. del Campo, Co-PI: Dr. J. Avendaño)
  • Evolution of antibiotic resistance, mechanisms, and new strategies (PI: Dr. J.C. Rodríguez-Beltrán, Co-PI: Dr. C. Herencias)
  • Diagnostic and clinical implications of viral variability in national and international cohorts. Development of nanotechnologies in the early molecular diagnosis of HIV with aptamers (PI: Dr. A. Holguín)
  • Strategies for diagnostic improvement and genomic epidemiology of sexually transmitted (HIV/STIs/hepatitis) and respiratory viral infections (PI: Dr. J.C. Galán)
  • Cystic fibrosis: self-management for nutritional intervention in the pursuit of patient well-being (PI: Dr. J.d.D. Caballero and Dr. S. Vicente)

Location

Ramón y Cajal University Hospital

  • Molecular Microbiology Lab. Floor -1 Left (PI: R. Cantón, J.C. Galán, P. Ruiz-Garbajosa and J.d.D. Caballero)
  • Molecular Epidemiology of HIV-1 Lab. Floor -2 Right (PI: Á. Holguín)
  • Microbiology Lab. Floor -1 Right (PI: M. Hernández)
  • Bacterial Evolution Lab - Teaching Building (PI: F. Baquero, T.M. Coque, A.E. Pérez-Cobas, C. Herencias, J.C. Rodríguez-Beltrán and Dr. J. Alves Gama)
  • Cystic Fibrosis Unit. Floor 2 Left (San Vicente)

Keywords

Population biology, antimicrobial resistance, respiratory infection, microbiota, metagenomics, HIV, clinical trials of diagnostic tests, phage therapy