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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

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Only original articles, editorials, guidelines.

  • Boattini M, Bianco G, Bastos P, Mavromanolaki VE, Maraki S, Spiliopoulou A, Kakouris V, Kalchev Y, Budimir A, Bedenic B, Rubic Z, Licker M, Musuroi C, Juhász E, Kristóf K, Pirs M, Velimirovic I, Berktold M, Liptáková A, Krajcikova A, Drevinek P, Gryndlerova A, Brzychczy-Wloch M, Olechowska-Jarzab A, Bielec F, Brauncajs M, Podsiadly E, Nurzynska G, Zalas-Wiecek P, Riesbeck K, Andersson HS, Tønjum T, Berild JC, Leegaard TM, Rasmussen AN, Schønning K, Glöckner S, Rödel J, Badr MT, Häcker GA, Stark D, Hamprecht A, Dudakova A, Jantsch J, Mancini S, Quiblier C, Jacot D, Greub G, Ferniani T, Ambretti S, Calvo M, Stefani S, Schade R, Yusuf E, Koeveringe SVK, Vandamme S, Verroken A, Rodriguez-Villalobos H, Duigou F, Corvec S, Floch P, Massip C, Chainier D, Barraud O, Louissaint MB, Mizrahi A, Ali S, Doyle M, Egan C, McNicholas S, Colomina-Rodriguez J, Torres I, Luengo RG, Escartín MNL, Perez MBV, Halperin AV, García SF, Cantón R, Seruca M, Mendes VS, Carvalho D, Cavallo R, Cristino JM, Costa C.

    Diagnostic and epidemiological landscape of anaerobic bacteria in Europe, 2020-2023 (ANAEuROBE).

    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS . 65(6): 107478-107478.

    [doi:10.1016/j.ijantimicag.2025.107478]

  • Ortiz-Miravalles L, Prieto A, Kieffer N, Vergara E, Cantón R, San Millán Á, Baquero F, Hipólito A, Escudero JA.

    Effect of oxygen on antimicrobial resistance genes from a one health perspective.

    SCIENCE OF THE TOTAL ENVIRONMENT . 979: 179523-179523.

    [doi:10.1016/j.scitotenv.2025.179523]

  • Maruri-Aransolo A, Quintana E, Michelena-González M, Pastor-Vivero MD, Álvarez A, Girón R, Alarcón T, Luna-Paredes C, Máiz L, Vicente S, de Valbuena MR, Prados MC, Castillo-Corullón S, Selma MJ, Solé A, Cols-Roig M, Mondéjar-López P, Ruiz EP, Olveira C, Aguilera PC, Ruiz PB, Causapé CL, Figuerola J, Asensio O, Caballero-Pérez JD, Cantón R.

    Bronchopulmonary colonization patterns in Spanish people with cystic fibrosis: Results of a national multicentre study.

    Enfermedades Infecciosas Y Microbiologia Clinica (english Ed.) . 43(6): 309-316.

    [doi:10.1016/j.eimce.2024.08.008]

  • Gayoso-Cantero D, Corbacho-Loarte MD, Crespillo-Andújar C, Chamorro-Tojeiro S, Norman F, Perez-Molina JA, González-Sanz M, Martín O, Rubio JM, Gullón-Peña B, Del Campo Albendea L, López-Vélez R, Monge-Maillo B.

    Changes in Lipid Profile Secondary to Asymptomatic Malaria in Migrants from Sub-Saharan Africa: A Retrospective Analysis of a 2010-2022 Cohort.

    Tropical Medicine and Infectious Disease . 10(5): .

    [doi:10.3390/tropicalmed10050134]

  • García Romero R, López Cárdenes C, Crehuá Gaudiza E, Álvarez Beltrán M, Murray Hurtado M, Tutau Gómez C, Loverdos Eseverri I, Torcuato Rubio E, García Volpe C, Salcedo Lobato E, Medina Martínez M, Martin Fernández C, Moreno Álvarez A, Reyes Domínguez A, González Jiménez D.

    Improvement of intestinal inflammation after treatment with CFTR modulators in cystic fibrosis patients.

    Anales De Pediatria . 102(5): 503836-503836.

    [doi:10.1016/j.anpede.2025.503836]

  • Pastor-Vivero MD, Costa I Colomer J, Martín de Vicente C, Vicente-Santamaria S, Garcia Romero R, González Jiménez D, Luna Paredes C.

    Advances in the treatment of cystic fibrosis: CFTR modulators.

    Anales De Pediatria . 102(5): 503857-503857.

    [doi:10.1016/j.anpede.2025.503857]

  • Rodriguez-Temporal D, Adrados D, Alastruey-Izquierdo A, Alkorta M, Candela A, Canut A, Castro C, Cilla CG, de Dios Caballero J, Ercibengoa M, Fernández M, Fradejas I, Fraile O, Goyanes MJ, Gutiérrez A, López JI, López C, López-Calleja AI, López-Medrano R, Muñoz P, Ortega AM, Oviaño M, Peman J, Rodríguez-Mayo M, Ruiz A, Tristancho A, Rodríguez-Sánchez B.

    Current Performance of MALDI-TOF Mass Spectrometry Databases for the Identification of Dermatophyte Species.

    JOURNAL OF FUNGI . 11(5): .

    [doi:10.3390/jof11050356]

  • Crehuá-Gaudiza E, Vicente Santamaría S, Álvarez Beltrán M, Martín Fernández C, Tutau Gómez C, Loverdos Eseverri I, García Romero R, Torcuato Rubio E, Del Brío Castillo R, Garriga García M, Gascón Galindo C, Gutiérrez Martínez JR, Castro Millán AM, Sierra San Nicolás S, Ortiz Pérez P, García Volpe C, Salcedo Lobato E, De La Mano Hernández A, Fernández González SM, Reyes Domínguez A, Peña-Quintana L, González Jiménez D.

    Effect of cystic fibrosis modulator therapies on serum levels of fat-soluble vitamins.

    Jpgn Reports . 6(2): 146-152.

    [doi:10.1002/jpr3.70007]

  • de Córdoba-Ansón PF, Linares-Ambohades I, Baquero F, Coque TM, Pérez-Cobas AE.

    The Respiratory Tract Microbiome and Human Health.

    Microbial Biotechnology . 18(5): .

    [doi:10.1111/1751-7915.70147]

  • Arredondo-Alonso S, Pöntinen AK, Gama JA, Gladstone RA, Harms K, Tonkin-Hill G, Thorpe HA, Simonsen GS, Samuelsen Ø, Johnsen PJ, Corander J.

    Plasmid-driven strategies for clone success in Escherichia coli.

    NATURE COMMUNICATIONS . 16(1): 2921-2921.

    [doi:10.1038/s41467-025-57940-1]

  • Becerra-Aparicio F, Gómez-Zorrilla S, Hernández-García M, Xanthopoulou K, Gijón D, Siverio A, Berbel D, Cercenado E, Rivera A, De Malet A, Xercavins M, Ruiz De Gopegui E, Canoura-Fernández L, Martínez JA, Seral C, Del Pozo JL, Cotarelo M, Ponz R, Higgins PG, Durán-Jordà X, Cantón R, Oliver A, Horcajada JP, Ruiz-Garbajosa P.

    Whole Genome Sequencing Analysis of Klebsiella pneumoniae Isolates from Health Care-Associated Bacteremia of Urinary Origin in Spain: Findings from the Multicenter ITUBRAS-2 Cohort Study.

    Open forum infectious diseases . 12(4): .

    [doi:10.1093/ofid/ofaf164]

  • Ismail AS, Berryhill BA, Gil-Gil T, Manuel JA, Smith AP, Baquero F, Levin BR.

    The tradeoffs between persistence and mutation rates at sub-inhibitory antibiotic concentrations in Staphylococcus aureus.

    Microbiology spectrum . 13(4): .

    [doi:10.1128/spectrum.02479-24]

  • Serrano-Tomás MI, Cabello M, Moreno-Nuñez P, Sanz JC, Cantón R, Sánchez-Díaz AM.

    Invasive pneumococcal disease in a tertiary hospital in Madrid: are we using pneumococcal vaccine correctly?

    Enfermedades Infecciosas Y Microbiologia Clinica (english Ed.) . 43(4): 210-214.

    [doi:10.1016/j.eimce.2025.03.009]

  • Peñalva G, Cantón R, Pérez-Rodríguez MT, González-López JJ, Rodríguez-Baño J, Barrio-Tofiño ED, Kirkegaard-Biosca C, Sánchez-Romero I, Gutiérrez-Villanueva A, Marrodán-Ciordia T, Guerra-Laso JM, Rosario-Quintana CD, Suárez-Hormiga L, Cámara J, Puig-Asensio M, Heredero E, Sepúlveda MA, Rodríguez-Díaz JC, Merino E, Cercenado E, Villa S, Siller M, Arnaiz F, Seral C, Lepe JA, Cisneros JM, Paño-Pardo JR.

    Burden of bacterial antimicrobial resistance among hospitalised patients in Spain: findings from three nationwide prospective studies.

    LANCET REGIONAL HEALTH-EUROPE . 51: 101220-101220.

    [doi:10.1016/j.lanepe.2025.101220]

  • Vicente-Santamaría S, Tabares-González A, Gascón-Galindo C, Tutau-Gómez C, Álvarez-Beltrán M, Muñoz-Codoceo RA, Rubio-Murillo M, De-Los-Santos M, Salcedo-Lobato E, Masip-Simó E, García-Romero R, Fernández-Lorenzo AE, Moreno-Álvarez A, Serrano-Nieto J, Hierro-Llanillo L, Loverdos-Eseverri I, Crehuá-Gaudiza E, Juste-Ruiz M, Blitz-Castro E, Morales-Tirado A, López-Cárdenes CM, Bousoño-García C, González-Jiménez D.

    Current situation of pediatric cystic fibrosis-related liver disease: results of a Spanish nationwide study.

    EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY . 37(4): 505-509.

    [doi:10.1097/MEG.0000000000002917]

  • Ruedas-López A, Tato M, Lerma L, Esteban J, Muñoz-Egea MC, Toro C, Domingo D, Prados-Rosales R, López-Roa P.

    Infection model of THP-1 cells, growth dynamics, and antimicrobial susceptibility of clinical Mycobacterium abscessus isolates from cystic fibrosis patients: Results from a multicentre study.

    Plos One . 20(3): .

    [doi:10.1371/journal.pone.0319710]

  • Monge-Maillo B, Roger-Zapata D, Dronda F, Carrillo E, Moreno J, Corbacho-Loarte MD, Gayoso Cantero D, Martín O, Chamorro-Tojeiro S, Perez-Molina JA, Norman F, González-Sanz M, López-Vélez R.

    Case Report: Long-Term Follow-Up of Visceral Leishmaniasis and HIV Coinfected Patients Without Relapse: Lymphoproliferative Response After Stimulation with Soluble Leishmania Antigen.

    Microorganisms . 13(3): .

    [doi:10.3390/microorganisms13030686]

  • Meyer R, Arpe L, Kansu A, Kelly V, Lindley K, O'Meara M, Del Carmen Rivero M, van Zundert S, Vicente-Santamaría S, Žaja O, Oliveros E, Olivier L, Joosten K.

    Gastrointestinal changes in paediatric malnutrition that may impact on nutrition choice.

    Frontiers in Pediatrics . 13: 1523613-1523613.

    [doi:10.3389/fped.2025.1523613]