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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

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Only original articles, editorials, guidelines.

  • Budia-Silva M, Kostyanev T, Ayala-Montaño S, Bravo-Ferrer Acosta J, Garcia-Castillo M, Cantón R, Goossens H, Rodriguez-Baño J, Grundmann H, Reuter S.

    International and regional spread of carbapenem-resistant Klebsiella pneumoniae in Europe.

    NATURE COMMUNICATIONS . 15(1): 5092-5092.

    [doi:10.1038/s41467-024-49349-z]

  • García-Castillo M, Hernández-García M, Correa A, Coppi M, Griener T, Fritsche T, Pitart C, Sampaio J, Seifert H, Wake K, Wootton M, Vila J, Cantón R.

    In vitro activity of ozenoxacin against Staphylococcus aureus and Streptococcus pyogenes clinical isolates recovered in a worldwide multicentre study (2020-2022).

    Jac-Antimicrobial Resistance . 6(3): .

    [doi:10.1093/jacamr/dlae088]

  • Rodríguez-Villodres Á, Lepe-Balsalobre E, Ortiz De La Rosa JM, Giner Almaraz S, González De Herrero E, Cercenado E, García-Fernández S, Benito R, Ponz Mir R, Cantón R, Lepe JA.

    Activity of cefepime, carbapenems and new ß-lactam/ß-lactamase inhibitor combinations on Enterobacter cloacae complex and Klebsiella aerogenes in Spain (SMART 2016-2022).

    Jac-Antimicrobial Resistance . 6(3): .

    [doi:10.1093/jacamr/dlae087]

  • Corbacho-Loarte MD, Martín O, Chamorro-Tojeiro S, Crespillo-Andújar C, Norman FF, Pérez-Molina JA, Sanz MG, Cancio-Suárez MR, Ruiz-Calvo G, López AR, Rubio JM, López-Vélez R, Monge-Maillo B.

    Screening blood donors for malaria, can we increase the number of eligible donors? An observational retrospective study.

    MALARIA JOURNAL . 23(1): 179-179.

    [doi:10.1186/s12936-024-04966-3]

  • Maruri-Aransolo A, López-Causapé C, Hernández-García M, García-Castillo M, Caballero-Pérez JD, Oliver A, Cantón R.

    In vitro activity of cefiderocol in Pseudomonas aeruginosa isolates from people with cystic fibrosis recovered during three multicentre studies in Spain.

    The Journal of antimicrobial chemotherapy . 79(6): 1432-1440.

    [doi:10.1093/jac/dkae126]

  • Herencias C, Álvaro-Llorente L, Ramiro-Martínez P, Fernández-Calvet A, Muñoz-Cazalla A, DelaFuente J, Graf FE, Jaraba-Soto L, Castillo-Polo JA, Cantón R, San Millán Á, Rodríguez-Beltrán J.

    ß-lactamase expression induces collateral sensitivity in Escherichia coli.

    NATURE COMMUNICATIONS . 15(1): 4731-4731.

    [doi:10.1038/s41467-024-49122-2]

  • Santerre Henriksen A, Arena F, Attwood M, Canton R, Gatermann S, Naas T, Morrissey I, Longshaw C.

    In vitro activity of cefiderocol against European Enterobacterales, including isolates resistant to meropenem and recentß-lactam/ß-lactamase inhibitor combinations.

    Microbiology spectrum . 12(8): .

    [doi:10.1128/spectrum.04181-23]

  • Muñoz-Cazalla A, de Quinto I, Álvaro-Llorente L, Rodríguez-Beltrán J, Herencias C.

    The role of bacterial metabolism in human gut colonization.

    INTERNATIONAL MICROBIOLOGY . : .

    [doi:10.1007/s10123-024-00550-6]

  • Pina-Vaz C, Silva-Dias A, Martins-Oliveira I, Gomes R, Perez-Viso B, Cruz S, Rodrigues AG, Sarmento A, Cantón R.

    A multisite validation of a two hours antibiotic susceptibility flow cytometry assay directly from positive blood cultures.

    BMC MICROBIOLOGY . 24(1): 187-187.

    [doi:10.1186/s12866-024-03341-1]

  • Fernández-Ruiz M, Gioia F, Bodro M, Gutiérrez Martín I, Sabé N, Rodriguez-Álvarez R, Corbella L, López-Viñau T, Valerio M, Illaro A, Salto-Alejandre S, Cordero E, Arnaiz de Las Revillas F, Fariñas MC, Muñoz P, Vidal E, Carratalà J, Goikoetxea J, Ramos-Martínez A, Moreno A, Martín-Dávila P, Fortún J, Aguado JM.

    Isavuconazole Versus Voriconazole as the First-line Therapy for Solid Organ Transplant Recipients With Invasive Aspergillosis: Comparative Analysis of 2 Multicenter Cohort Studies.

    Transplantation . 108(11): 2260-2269.

    [doi:10.1097/TP.0000000000005082]

  • Aracil-Gisbert S, Fernández-de-Bobadilla MD, Guerra-Pinto N, Serrano-Calleja S, Pérez-Cobas AE, Soriano C, de Pablo R, Lanza VF, Pérez-Viso B, Reuters S, Hasman H, Cantón R, Baquero F, Coque TM.

    The ICU environment contributes to the endemicity of the "Serratia marcescens complex" in the hospital setting.

    Mbio . 15(5): . Number of citations: 1

    [doi:10.1128/mbio.03054-23]

  • Salamanca-Rivera E, Palacios-Baena ZR, Cañada JE, Moure Z, Pérez-Vázquez M, Calvo-Montes J, Martínez-Martínez L, Cantón R, Ruiz Carrascoso G, Pitart C, Navarro F, Bou G, Mulet X, González-López JJ, Sivianes F, Delgado-Valverde M, Pascual Á, Oteo-Iglesias J, Rodríguez-Baño J.

    Epidemiological and clinical characterization of community, healthcare-associated and nosocomial colonization and infection due to carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in Spain.

    Infection . 52(6): 2231-2240.

    [doi:10.1007/s15010-024-02267-0]

  • Maruri-Aransolo A, de Dios Caballero J, Michelena M, Medina-Pascual MJ, Carrasco G, Asensio O, Cols M, Cantón R.

    Evaluation of CHROMagar™ B. cepacia agar for the detection of Burkholderia cepacia complex species from sputum samples of patients with cystic fibrosis.

    EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES . 43(7): 1349-1353.

    [doi:10.1007/s10096-024-04845-4]

  • Pujol-Muncunill G, Navas-López VM, Ledder O, Cohen S, Lekar M, Turner D, Kolho KL, Levine A, Croft NM, Bronsky J, Shouval DS, Assa A, Harris R, Kiparissi F, Aloi M, Afzal NA, Tzivinikos C, Barrio J, Norden C, Vega MJB, Buderus S, de Valderrama AF, de Ridder L, García-Romero R, Medina E, Sánchez C, Velasco M, Vicente S, Wilson DC, Naik S, Hradsky O, Cococcioni L, Martin-de-Carpi J.

    STEP-CD study: ustekinumab use in paediatric Crohn's disease-a multicentre retrospective study from paediatric IBD Porto group of ESPGHAN.

    EUROPEAN JOURNAL OF PEDIATRICS . 183(8): 3253-3262.

    [doi:10.1007/s00431-024-05588-2]

  • Liljegren MM, Gama JA, Johnsen PJ, Harms K.

    The recombination initiation functions DprA and RecFOR suppress microindel mutations in Acinetobacter baylyi ADP1.

    MOLECULAR MICROBIOLOGY . 122(1): 1-10.

    [doi:10.1111/mmi.15277]

  • Asensio-Grau A, Ferriz-Jordán M, Hervás D, Heredia A, García-Hernández J, Garriga M, Masip E, Carmen Collado M, Andrés A, Ribes-Koninckx C, Calvo-Lerma J.

    Faecal lipid profile as a new marker of fat maldigestion, malabsorption and microbiota.

    PEDIATRIC RESEARCH . : .

    [doi:10.1038/s41390-024-03209-0]

  • Boattini M, Bianco G, Llorente LI, Acero LA, Nunes D, Seruca M, Mendes VS, Almeida A, Bastos P, Rodríguez-Villodres Á, Gascón AG, Halperin AV, Cantón R, Escartín MNL, González-López JJ, Floch P, Massip C, Chainier D, Barraud O, Dortet L, Cuzon G, Zancanaro C, Mizrahi A, Schade R, Rasmussen AN, Schønning K, Hamprecht A, Schaffarczyk L, Glöckner S, Rödel J, Kristóf K, Balonyi Á, Mancini S, Quiblier C, Fasciana T, Giammanco A, Paglietti B, Rubino S, Budimir A, Bedenic B, Rubic Z, Marinovic J, Gartzonika K, Christaki E, Mavromanolaki VE, Maraki S, Yalçin TY, Azap ÖK, Licker M, Musuroi C, Talapan D, Ovidiu VC, Comini S, Zalas-Wiecek P, Michalska A, Cavallo R, Cristino JM, Costa C.

    Enterobacterales carrying chromosomal AmpC ß-lactamases in Europe (EuESCPM): epidemiology and antimicrobial resistance burden from a cohort of 27 hospitals, 2020-2022.

    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS . 63(5): 107115-107115. Number of citations: 2

    [doi:10.1016/j.ijantimicag.2024.107115]

  • Taylor-Salmon E, Hill V, Paul LM, Koch RT, Breban MI, Chaguza C, Sodeinde A, Warren JL, Bunch S, Cano N, Cone M, Eysoldt S, Garcia A, Gilles N, Hagy A, Heberlein L, Jaber R, Kassens E, Colarusso P, Davis A, Baudin S, Rico E, Mejía-Echeverri Á, Scott B, Stanek D, Zimler R, Muñoz-Jordán JL, Santiago GA, Adams LE, Paz-Bailey G, Spillane M, Katebi V, Paulino-Ramírez R, Mueses S, Peguero A, Sánchez N, Norman FF, Galán JC, Huits R, Hamer DH, Vogels CBF, Morrison A, Michael SF, Grubaugh ND.

    Travel surveillance uncovers dengue virus dynamics and introductions in the Caribbean.

    NATURE COMMUNICATIONS . 15(1): 3508-3508.

    [doi:10.1038/s41467-024-47774-8]