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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Bastón-Paz N, Moreno-Blanco A, Palacios E, Olavarrieta L, Galeano J, Garriga M, Máiz L, Vicente-Santamaría S, Oteo-Iglesias J, López-Causapé C, Fuentes I, Oliver A, Cantón R, del Campo R, de Dios-Caballero J.

    Exploring the complexities of intestinal and pulmonary microbiota in cystic fibrosis: A multi-omics approach

    RESPIRATORY MEDICINE . 248: 108331-108331. Number of citations: 1

    [doi:10.1016/j.rmed.2025.108331]

  • Gayoso Cantero D, Fernández-González P, Chamorro-Tojeiro S, Quereda C, Tato M, Berna-Rico E, Naharro-Rodríguez J, Perez-Molina JA.

    Clinical, therapeutic, and stigma-related challenges in leprosy and the emerging role of apremilast in managing leprosy reactions

    Travel Medicine and Infectious Disease . 68: 102918-102918.

    [doi:10.1016/j.tmaid.2025.102918]

  • Guadarrama-Orozco KD, Esquivel-Hernández DA, Islas-Tolentino MÁ, Husain FM, Quezada H, García-Reyes S, Franco B, Marroquin-Mendiola DL, Lucero-Gil MG, Olvera-Falfan LP, Estrada-Velasco ÁY, Fabián Del Olmo MJ, Cocotl-Yañez M, Tomas M, Peña-Ocaña BA, Maeda T, Khan A, Arshad M, Cantón R, Oliver A, Kidd TJ, Valdez A, Cadet F, Toya S, Fontaine N, Ceapa CD, Kirigo J, Wood TK, García-Contreras R.

    Challenging the paradigm: non-canonical exoprotease cheating in clinical Pseudomonas aeruginosa isolates

    FEMS MICROBIOLOGY ECOLOGY . 101(11): . Number of citations: 1

    [doi:10.1093/femsec/fiaf106]

  • Valadés-Alcaraz A, Medina-Sánchez C, Reinosa R, Ventosa-Cubillo J, Ventosa-Cubillo V, Holguín Á.

    Design and characterisation of high-affinity aptamers for detecting HIV integrase

    Analytica Chimica Acta . 1373: 344545-344545.

    [doi:10.1016/j.aca.2025.344545]

  • Labiod N, Sánchez-Seco MP, Goikoetxea J, Zurita ND, Norman FF, Martínez MM, Alonso PA, Hernández-Betancor A, Sempere-Alcocer MA, Moure Z, Ocete MD, Vicente MR, de la Calle-Prieto F, Gallego M, Domingo LC, Galán JC, Camprubí-Ferrer D, Meilán C, Perez-Hernandez I, Cabezón I, Hernández FJ, Bernal E, Vázquez A.

    Case series of Oropouche fever among travellers returning from Cuba to Spain, 2024

    Eurosurveillance . 30(41): . Number of citations: 6

    [doi:10.2807/1560-7917.ES.2025.30.41.2400719]

  • Asensi-Díaz E, Barbero Del Olmo L, Urrutia P, Lario A, Gómez-G de la Pedrosa E, García-Ruiz de Morales AG, Martín-Dávila P, Fortún J.

    When Fungal Prophylaxis Fails: A Rare Case of Rhodotorula mucilaginosa Fungemia with Suspected Abdominal Origin

    Journal of Fungi . 11(10): . Number of citations: 2

    [doi:10.3390/jof11100723]

  • Halperin AV, Escudero R, García-Castillo M, Cardenas-Isasi MJ, Gioia F, Cobo J, Sánchez-Díaz AM, Cantón R.

    Randomized controlled diagnostic trial to assess dRAST time to result and its utility for antimicrobial stewardship recommendation in bacteremic patients

    Microbiology Spectrum . 13(10): . Number of citations: 4

    [doi:10.1128/spectrum.00288-25]

  • Sastre-Femenia MÀ, Fernández-Muñoz A, Gomis-Font MA, Taltavull B, López-Causapé C, Arca-Suárez J, Martínez-Martínez L, Cantón R, Larrosa N, Oteo-Iglesias J, Oliver A.

    Spanish nationwide survey of Pseudomonas aeruginosa cefiderocol antimicrobial susceptibility and resistance genomics

    International Journal of Antimicrobial Agents . 66(4): 107563-107563. Number of citations: 9

    [doi:10.1016/j.ijantimicag.2025.107563]

  • Daneri L, Urbano A, Escudero-Sánchez R, Halperin AV, Moreno-Blanco A, Corbacho MD, Suárez-Carantoña C, Rodríguez-Jiménez C, Serrano-Villar S, Campo RD, Cobo J.

    Lyophilised fecal microbiota transfer in capsules for recurrent Clostridioides difficile infection

    International Journal of Antimicrobial Agents . 66(4): 107561-107561. Number of citations: 1

    [doi:10.1016/j.ijantimicag.2025.107561]

  • Rico-Caballero V, Romero-Rivera M, Moreno-Blanco A, Aira A, Casals-Pascual C, Rodríguez-Jiménez C, Quereda C, Soriano A, Del Campo R.

    Fecal microbiota transplant as treatment for recurrent urinary tract infections: a proof-of-concept study

    EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES . 44(10): 2549-2554. Number of citations: 5

    [doi:10.1007/s10096-025-05202-9]

  • Rodriguez-Tierno S, Sáez de la Fuente J, Fuertes Pina L, Escudero-Sánchez R, Ruiz-Garbajosa P, Guijarro Martínez P, Gioia F, Pintor Recuenco MDR, Álvarez-Díaz A.

    Real-life experience with use of cefiderocol in non-critically ill patients in a tertiary care hospital.

    Enfermedades Infecciosas Y Microbiologia Clinica (english Ed.) . 43(8): 510-514.

    [doi:10.1016/j.eimce.2025.05.009]

  • Canton R, Halperín AV.

    Diagnostic stewardship in sepsis: minding the gap from the microbiology lab to ward

    Revista Espanola de Quimioterapia . 38(Suppl 1): 11-20. Number of citations: 2

    [doi:10.37201/req/s01.02.2025]

  • Avendaño-Ortiz J, Tribaldo A, Ballestero L, Gómez LA, Gracia I, Rodríguez JF, Ramírez NB, Bodoque-Villar R, Vaz-Salgado MÁ, Del Campo R, Redondo-Calvo FJ.

    Antimicrobial Activity of Natural Extracts Against Catheter-Colonizing Methicillin-Resistant Staphylococcus aureus Clinical Isolates

    Biomedicines . 13(9): . Number of citations: 1

    [doi:10.3390/biomedicines13092150]

  • Pérez-Molina JA, Moreno E, Crespillo-Andújar C, Chamorro-Tojeiro S, Arsuaga M, Olavarrieta L, Martín O, Monge-Maillo B, Norman F, Lanza VF, Serrano-Villar S.

    Chagas disease induces gut microbial metabolic stress: Disruption of energy and nucleotide pathways and partial reversal by antiparasitic therapy (TRIPOBIOME-2 study)

    Travel Medicine and Infectious Disease . 67: 102881-102881. Number of citations: 1

    [doi:10.1016/j.tmaid.2025.102881]

  • Torumkuney D, Canton R, Pitart C, Sanguinetti M, Vismara C, Farina C, Sambri V, Hawser S, Manoharan A.

    Results from the Survey of Antibiotic Resistance (SOAR) 2018-21 in Italy and Spain: data based on CLSI, EUCAST (dose-specific) and pharmacokinetic/pharmacodynamic (PK/PD) breakpoints

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 80(Supplement_3): 2-18. Number of citations: 2

    [doi:10.1093/jac/dkaf283]

  • Boattini M, Aceti A, Bastos P, Mavromanolaki VE, Maraki S, Spiliopoulou A, Kakouris V, Kalchev Y, Budimir A, Bedenic B, Rubic Z, Licker M, Musuroi C, Juhász E, Kristóf K, Pirs M, Velimirovic I, Berktold M, Liptáková A, Krajcíková A, Drevinek P, Gryndlerova A, Brzychczy-Wloch M, Olechowska-Jarzab A, Bielec F, Brauncajs M, Podsiadly E, Nurzynska G, Zalas-Wiecek P, Michalska A, Riesbeck K, Andersson HS, Tønjum T, Berild JC, Leegaard TM, Rasmussen AN, Schønning K, Glöckner S, Rödel J, Badr MT, Häcker GA, Stark D, Hamprecht A, Dudakova A, Jantsch J, Mancini S, Quiblier C, Jacot D, Greub G, Ferniani T, Ambretti S, Calvo M, Stefani S, Schade R, Yusuf E, van Kleef-van Koeveringe S, Vandamme S, Verroken A, Rodriguez-Villalobos H, Duigou F, Corvec S, Floch P, Massip C, Chainier D, Barraud O, Louissaint MB, Mizrahi A, Ali S, Doyle M, Egan C, McNicholas S, Colomina-Rodriguez J, Torres I, Gillaranz Luengo R, Larrosa Escartín MN, Viñado Perez MB, Halperin AV, Fuente García S, Cantón R, Seruca M, Santos Mendes V, Carvalho D, Cavallo R, Melo Cristino J, Costa C, Bianco G.

    A European survey on anaerobes from paediatric blood cultures: a comparative analysis with adults

    EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES . 44(9): 2207-2217. Number of citations: 1

    [doi:10.1007/s10096-025-05185-7]

  • Cercenado E, Alcalá L, Irigoyen-von-Sierakowski Á, Rodríguez-Sánchez B, Marín M.

    Activity of imipenem-relebactam, ceftolozane-tazobactam and comparators against clinical isolates of Enterobacterales and Pseudomonas aeruginosa causing severe infections in hematological and oncological patients: A prospective multicenter study.

    International Journal of Antimicrobial Agents . 66(3): 107534-107534. Number of citations: 3

    [doi:10.1016/j.ijantimicag.2025.107534]

  • Alonso S, Salazar E, Gálvez N, Navas J, Quintana C, Orózco N, Prieto L, Navarro ML, Guillén S, Gómez-Alba JM, Medina-Sánchez C, Juarez J, Holguín A.

    Prevalence of acquired resistance to antiretrovirals in children and adolescents living with HIV under clinical follow-up at the Roosevelt Hospital in Guatemala

    Journal of Infection and Public Health . 18(9): 102827-102827. Number of citations: 3

    [doi:10.1016/j.jiph.2025.102827]