Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Dionisio F, Baquero F, Fuertes M.

    Psychological and cultural factors influencing antibiotic prescription.

    TRENDS IN MICROBIOLOGY . 31(6): 559-570. Number of citations: 7

    [doi:10.1016/j.tim.2022.12.010]

  • Pintado V, Ruiz-Garbajosa P, Aguilera-Alonso D, Baquero-Artigao F, Bou G, Cantón R, Grau S, Gutiérrez-Gutiérrez B, Larrosa N, Machuca I, Martínez Martínez L, Montero MM, Morte-Romea E, Oliver A, Paño-Pardo JR, Sorlí L.

    Executive summary of the consensus document of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) on the diagnosis and antimicrobial treatment of infections due to carbapenem-resistant Gram-negative bacteria.

    Enfermedades Infecciosas Y Microbiologia Clinica (english Ed.) . 41(6): 360-370.

    [doi:10.1016/j.eimce.2022.06.014]

  • Vázquez-Morón S, Iglesias-Caballero M, Lepe JA, Garcia F, Melón S, Marimon JM, García de Viedma D, Folgueira MD, Galán JC, López-Causapé C, Benito-Ruesca R, Alcoba-Florez J, Gonzalez Candelas F, Toro M, Fajardo M, Ezpeleta C, Lázaro F, Pérez Castro S, Cuesta I, Zaballos A, Pozo F, Casas I, On Behalf Of Relecov Network Members.

    Enhancing SARS-CoV-2 Surveillance through Regular Genomic Sequencing in Spain: The RELECOV Network.

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 24(10): .

    [doi:10.3390/ijms24108573]

  • Castillo-Polo JA, Hernández-García M, Morosini MI, Pérez-Viso B, Soriano C, de Pablo R, Cantón R, Ruiz-Garbajosa P.

    Outbreak by KPC-62-producing ST307 Klebsiella pneumoniae isolates resistant to ceftazidime/avibactam and cefiderocol in a university hospital in Madrid, Spain.

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 78(5): 1259-1264. Number of citations: 1

    [doi:10.1093/jac/dkad086]

  • Rodrigues C, Lanza VF, Peixe L, Coque TM, Novais Â.

    Phylogenomics of Globally Spread Clonal Groups 14 and 15 of Klebsiella pneumoniae.

    Microbiology spectrum . 11(3): .

    [doi:10.1128/spectrum.03395-22]

  • Baquero F, Martínez JL, Sánchez A, Fernández-de-Bobadilla MD, San-Millán A, Rodríguez-Beltrán J.

    Bacterial Subcellular Architecture, Structural Epistasis, and Antibiotic Resistance

    BIOLOGY-BASEL . 12(5): . Number of citations: 3

    [doi:10.3390/biology12050640]

  • Candela A, Guerrero-López A, Mateos M, Gómez-Asenjo A, Arroyo MJ, Hernandez-García M, Del Campo R, Cercenado E, Cuénod A, Méndez G, Mancera L, Caballero JD, Martínez-García L, Gijón D, Morosini MI, Ruiz-Garbajosa P, Egli A, Cantón R, Muñoz P, Rodríguez-Temporal D, Rodríguez-Sánchez B.

    Automatic Discrimination of Species within the Enterobacter cloacae Complex Using Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry and Supervised Algorithms

    JOURNAL OF CLINICAL MICROBIOLOGY . 61(4): .

    [doi:10.1128/jcm.01049-22]

  • Broncano-Lavado A, Barrado L, Lopez-Roa P, Cacho J, Domingo D, Hernandez S, Garcia-Martinez J, Millan MR, Perez-Cecilia E, Ruiz-Serrano MJ, Salso S, Simon M, Tato M, Toro C, Valverde-Canovas JF, Esteban J.

    Clinical Evaluation of Nontuberculous Mycobacteria (NTM) Elite Agar, a New Medium for the Isolation of NTM: a Multicenter Study

    JOURNAL OF CLINICAL MICROBIOLOGY . 61(4): .

    [doi:10.1128/jcm.00036-23]

  • Blanco-Martín T, Guzmán-Puche J, Riazzo C, Gasca-Santiyán M, Hernández-García M, Cantón R, Torre-Cisneros J, Herrera C, Martínez-Martínez L.

    Phenotypic and Molecular Characterization of an Enterobacter ludwigii Clinical Isolate Carrying a Plasmid-Mediated bla(IMI-6) Gene.

    Microbiology spectrum . 11(3): .

    [doi:10.1128/spectrum.04620-22]

  • Coque TM, Cantón R, Pérez-Cobas AE, Fernández-de-Bobadilla MD, Baquero F.

    Antimicrobial Resistance in the Global Health Network: Known Unknowns and Challenges for Efficient Responses in the 21st Century.

    Microorganisms . 11(4): . Number of citations: 2

    [doi:10.3390/microorganisms11041050]

  • García-González N, Beamud B, Fuster B, Giner S, Domínguez MV, Sánchez A, Sevilla J, Coque TM, Gimeno C, González-Candelas F.

    Tracking the Emergence and Dissemination of a bla(NDM-23) Gene in a Multidrug Resistance Plasmid of Klebsiella pneumoniae.

    Microbiology spectrum . 11(2): . Number of citations: 1

    [doi:10.1128/spectrum.02585-22]

  • Sainz de la Maza S, Walo-Delgado PE, Rodríguez-Domínguez M, Monreal E, Rodero-Romero A, Chico-García JL, Pariente R, Rodríguez-Jorge F, Ballester-González R, Villarrubia N, Romero-Hernández B, Masjuan J, Costa-Frossard L, Villar LM.

    Short- and Long-Term Humoral and Cellular Immune Responses to SARS-CoV-2 Vaccination in Patients with Multiple Sclerosis Treated with Disease-Modifying Therapies.

    Vaccines . 11(4): . Number of citations: 1

    [doi:10.3390/vaccines11040786]

  • Martín Sánchez FJ, Martínez-Sellés M, Molero García JM, Moreno Guillén S, Rodríguez-Artalejo FJ, Ruiz-Galiana J, Cantón R, De Lucas Ramos P, García-Botella A, García-Lledó A, Hernández-Sampelayo T, Gómez-Pavón J, González Del Castillo J, Martín-Delgado MC, Bouza E.

    Insights for COVID-19 in 2023.

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 36(2): 114-124. Number of citations: 4

    [doi:10.37201/req/122.2022]

  • Avendaño-Ortiz J, Redondo-Calvo FJ, Lozano-Rodríguez R, Terrón-Arcos V, Bergón-Gutiérrez M, Rodríguez-Jiménez C, Rodríguez JF, Del Campo R, Gómez LA, Bejarano-Ramírez N, Pérez-Ortiz JM, López-Collazo E.

    Thiosulfinate-Enriched Allium sativum Extract Exhibits Differential Effects between Healthy and Sepsis Patients: The Implication of HIF-1a.

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 24(7): .

    [doi:10.3390/ijms24076234]

  • Escudero-Sánchez R, Rubio Martín E, Vizcarra P, Braojos Sánchez F, Diaz Gago Á, Del Campo Albendea L, Muriel A, Halperin A, Ponce Alonso M, Moreno Guillén S, Cobo J.

    Conventional versus extended-pulsed fidaxomicin dosing in patients at high risk of recurrence of Clostridioides difficile infection: a propensity score analysis.

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 78(3): 823-827.

    [doi:10.1093/jac/dkad019]

  • Pérez-Galera S, Bravo-Ferrer JM, Paniagua M, Kostyanev T, de Kraker MEA, Feifel J, Sojo-Dorado J, Schotsman J, Cantón R, Daikos GL, Carevic B, Dragovac G, Tan LK, Raka L, Hristea A, Viale P, Akova M, Reguera JM, Valiente de Santis L, Torre-Cisneros J, Cano Á, Roilides E, Radulovic L, Kirakli C, Shaw E, Falagas ME, Pintado V, Goossens H, Bonten MJ, Gutiérrez-Gutiérrez B, Rodriguez-Baño J.

    Risk factors for infections caused by carbapenem-resistant Enterobacterales: an international matched case-control- control study (EURECA)

    Eclinicalmedicine . 57: 101871-101871. Number of citations: 8

    [doi:10.1016/j.eclinm.2023.101871]

  • Cerrudo V, Cortés-Cuevas JL, García-Fernández S, Morosini MI, Cantón R, Sánchez-Díaz AM.

    Usefulness of EUCAST rapid antibiotic susceptibility breakpoints and screening cut-off values directly from blood cultures for the inference of ß-lactam resistance mechanisms in Enterobacterales.

    Jac-Antimicrobial Resistance . 5(1): . Number of citations: 1

    [doi:10.1093/jacamr/dlad017]

  • Avendaño-Ortiz J, Ponce-Alonso M, Llanos-González E, Barragán-Prada H, Barbero-Herranz R, Lozano-Rodríguez R, Márquez-Garrido FJ, Hernández-Pérez JM, Morosini MI, Cantón R, Del Campo R, López-Collazo E.

    The Impact of Colistin Resistance on the Activation of Innate Immunity by Lipopolysaccharide Modification

    INFECTION AND IMMUNITY . 91(2): . Number of citations: 1

    [doi:10.1128/iai.00012-23]