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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Merino Sánchez-Cañete A, López Cárdenes CM, Vicente Santamaría S, Gutiérrez Martínez JR, Suárez González M, Álvarez Merino M, González Jiménez D.

    Increased fat mass and obesity risk after elexacaftor-tezacaftor-ivacaftor therapy in young adults with cystic fibrosis.

    Frontiers in Nutrition . 11: 1477674-1477674. Number of citations: 12

    [doi:10.3389/fnut.2024.1477674]

  • Bertagnolio S, Dobreva Z, Centner CM, Olaru ID, Donà D, Burzo S, Huttner BD, Chaillon A, Gebreselassie N, Wi T, Hasso-Agopsowicz M, Allegranzi B, Sati H, Ivanovska V, Kothari KU, Balkhy HH, Cassini A, Hamers RL, Weezenbeek KV.

    WHO global research priorities for antimicrobial resistance in human health.

    Lancet Microbe . 5(11): 100902-100902. Number of citations: 187

    [doi:10.1016/S2666-5247(24)00134-4]

  • Sastre-Dominguez J, DelaFuente J, Toribio-Celestino L, Herencias C, Herrador-Gómez P, Costas C, Hernández-García M, Cantón R, Rodríguez-Beltrán J, Santos-Lopez A, San Millan A.

    Plasmid-encoded insertion sequences promote rapid adaptation in clinical enterobacteria.

    Nature Ecology & Evolution . 8(11): 2097-2112. Number of citations: 19

    [doi:10.1038/s41559-024-02523-4]

  • Guinea J, Alcoceba E, Padilla E, Ramírez A, De Carolis E, Sanguinetti M, Muñoz-Algarra M, Durán-Valle T, Quiles-Melero I, Merino P, González-Romo F, Sánchez-García A, Gómez-García-de-la-Pedrosa E, Pérez-Ayala A, Mantecón-Vallejo MÁ, Pemán J, Cuétara MS, Zurita ND, García-Esteban C, Martínez-Jiménez MDC, Sánchez Castellano MÁ, Reigadas E, Muñoz P, Escribano P.

    Fluconazole-resistant Candida parapsilosis: fast detection of the Y132F ERG11p substitution, and a proposed microsatellite genotyping scheme.

    CLINICAL MICROBIOLOGY AND INFECTION . 30(11): 1447-1452. Number of citations: 9

    [doi:10.1016/j.cmi.2024.07.002]

  • Colomer Font C, Lillo Gonzalez MJ, Lopez de Munain Marques L, Formigo Couceiro J, Martínez Rodríguez ME, Alonso Álvarez B, Sanz Ayán MP, Santandreu Jimenez ME, Martin Mourelle R, Pujol Blaya V, De Miguel Benadiba C, Sanchez Tarifa P, Bascuñana Ambrós H.

    Recomendaciones de No hacer en rehabilitación y medicina física desde distintos ámbitos de intervención.

    Rehabilitacion . 58(4): 100870-100870. Number of citations: 1

    [doi:10.1016/j.rh.2024.100870]

  • Tedim AP, Almeida-Santos AC, Lanza VF, Novais C, Coque TM, Freitas AR, Peixe L.

    Bacteriocin distribution patterns in Enterococcus faecium and Enterococcus lactis: bioinformatic analysis using a tailored genomics framework.

    APPLIED AND ENVIRONMENTAL MICROBIOLOGY . 90(10): . Number of citations: 21

    [doi:10.1128/aem.01376-24]

  • Maruri-Aransolo A, Hernandez-García M, Barbero R, Michelena M, Pastor-Vivero MD, Mondejar-Lopez P, Solé A, Cantón R, Caballero-Pérez JD.

    Genomic characterization of MRSA recovered from people with cystic fibrosis during two Spanish multicentre studies (2013 and 2021).

    JAC-Antimicrobial Resistance . 6(5): . Number of citations: 2

    [doi:10.1093/jacamr/dlae160]

  • Fernandez-Gonzalez, Pablo, Garcia-Donoso, Carmen, Garcia-Mouronte, Emilio, Alejo Fernandez-Baillo, Jose Luis, De Nicolas-Ruanes, Belen, Berna-Rico, Emilio, Perez-Ayala, Ana, Gomez-Garcia de la Pedrosa, Elia.

    Trichophyton indotineae extensive tinea: Successful posaconazole treatment in four cases from Spain.

    CLINICAL AND EXPERIMENTAL DERMATOLOGY . : . Number of citations: 7

    [doi:10.1093/ced/llae417]

  • de Lorenzo V, Baquero F, Aguilar A.

    Carlos Asensio and the dawn of molecular microbial ecology.

    INTERNATIONAL MICROBIOLOGY . : .

    [doi:10.1007/s10123-024-00596-6]

  • Rodriguez-Mateos, Mariano, Carlos, Silvia, Jaso, Javier, Holguin, Africa, Reina, Gabriel.

    Influence of Hematocrit and Storage Temperature on the Stability of Dried Blood Samples in Serological Analyses of Tetanus, Diphtheria, and Pertussis

    Diagnostics . 14(19): . Number of citations: 2

    [doi:10.3390/diagnostics14192195]

  • Marín-Miret J, Pérez-Cobas AE, Domínguez-Santos R, Pérez-Rocher B, Latorre A, Moya A.

    Adaptability of the gut microbiota of the German cockroach Blattella germanica to a periodic antibiotic treatment.

    MICROBIOLOGICAL RESEARCH . 287: 127863-127863. Number of citations: 6

    [doi:10.1016/j.micres.2024.127863]

  • Cortes-Lara S, Medina-Reatiga P, Barrio-Tofiño ED, Gomis-Font MA, Cabot G, Gómez-Romano F, Ayestarán I, Colomar A, Palou-Rotger A, Oteo-Iglesias J, Campo RD, Cantón R, Horcajada JP, López-Causapé C, Oliver A.

    Monitoring of Pseudomonas aeruginosa mutational resistome dynamics using an enrichment panel for direct sequencing of clinical samples.

    EBioMedicine . 108: 105367-105367. Number of citations: 9

    [doi:10.1016/j.ebiom.2024.105367]

  • Sabença C, Romero-Rivera M, Barbero-Herranz R, Sargo R, Sousa L, Silva F, Lopes F, Abrantes AC, Vieira-Pinto M, Torres C, Igrejas G, Del Campo R, Poeta P.

    Molecular Characterization of Multidrug-Resistant Escherichia coli from Fecal Samples of Wild Animals.

    Veterinary Sciences . 11(10): . Number of citations: 11

    [doi:10.3390/vetsci11100469]

  • Liljegren, Mikkel M., Gama, Joao A., Johnsen, Pal J., Harms, Klaus.

    Plasmids affect microindel mutations in Acinetobacter baylyi ADP1

    PLASMID . 131: . Number of citations: 2

    [doi:10.1016/j.plasmid.2024.102733]

  • Gil-Gil T, Berryhill BA, Manuel JA, Smith AP, McCall IC, Baquero F, Levin BR.

    The evolution of heteroresistance via small colony variants in Escherichia coli following long term exposure to bacteriostatic antibiotics.

    Nature Communications . 15(1): 7936-7936. Number of citations: 20

    [doi:10.1038/s41467-024-52166-z]

  • Zhou H, Buetti N, Pérez-Galera S, Bravo-Ferrer J, Gutiérrez-Gutiérrez B, Paniagua-García M, Feifel J, Sauser J, Kostyanev T, Canton R, Tan LK, Basoulis D, Pintado V, Roilides E, Dragovac G, Torre-Cisneros J, Mediç D, Akova M, Goossens H, Bonten M, Harbarth S, Rodriguez-Baño J, De Kraker MEA.

    Risk factors for bloodstream infections due to carbapenem-resistant Enterobacterales: a nested case-control-control study.

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 79(9): 2132-2141. Number of citations: 19

    [doi:10.1093/jac/dkae157]

  • Cabello M, Hernández-García M, Maruri-Aransolo A, Michelena M, Pérez-Viso B, Ponce-Alonso M, Cantón R, Ruiz-Garbajosa P.

    Occurrence of multi-carbapenemase-producing Enterobacterales in a tertiary hospital in Madrid (Spain): A new epidemiologic scenario.

    Journal of Global Antimicrobial Resistance . 38: 281-291. Number of citations: 14

    [doi:10.1016/j.jgar.2024.06.012]

  • Cancio-Suarez, Marta Rosas, Martin-Jimenez, Esther, Rodriguez-Dominguez, Mario, Da Silva, Ana Maria Garcia, Fernandez-Felix, Borja M., Romero-Hernandez, Beatriz, Cardenas-Isasi, Maria Jose, Moreno, Santiago, Serrano-Villar, Sergio, Sanchez-Conde, Matilde.

    Chlamydia Trachomatis Prevalence in Asymptomatic Women in Madrid: Study Findings and Their Association with Risk Factors and Mental Health

    Biomedicines . 12(9): . Number of citations: 1

    [doi:10.3390/biomedicines12091999]