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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Pérez-Mies B, Caniego-Casas T, Bardi T, Carretero-Barrio I, Benito A, García-Cosío M, González-García I, Pizarro D, Rosas M, Cristóbal E, Ruano Y, Garrido MC, Rigual-Bobillo J, de Pablo R, Galán JC, Pestaña D, Palacios J.

    Progression to lung fibrosis in severe COVID-19 patients: A morphological and transcriptomic study in postmortem samples

    Frontiers In Medicine . 9: 976759-976759. Number of citations: 3

    [doi:10.3389/fmed.2022.976759]

  • Vivancos-Gallego MJ, Sánchez-Conde M, Rodríguez-Domínguez M, Fernandez-Gonzalez P, Martínez-García L, Garcia-Mouronte E, Martínez-Sanz J, Moreno-Zamora AM, Casado JL, Ron R, Galán JC, Pérez-Elías MJ, Moreno S.

    Human Monkeypox in People With HIV: Transmission, Clinical Features, and Outcome

    Open forum infectious diseases . 9(11): . Number of citations: 10

    [doi:10.1093/ofid/ofac557]

  • Díaz-García J, Gómez A, Machado M, Alcalá L, Reigadas E, Sánchez-Carrillo C, Pérez-Ayala A, de la Pedrosa EG, González-Romo F, Cuétara MS, García-Esteban C, Quiles-Melero I, Zurita ND, Algarra MM, Durán-Valle MT, Sánchez-García A, Muñoz P, Escribano P, Guinea J, On Behalf Of The Candimad Study Group.

    Candida Genotyping of Blood Culture Isolates from Patients Admitted to 16 Hospitals in Madrid: Genotype Spreading during the COVID-19 Pandemic Driven by Fluconazole-Resistant C. parapsilosis

    JOURNAL OF FUNGI . 8(11): . Number of citations: 6

    [doi:10.3390/jof8111228]

  • Drevinek P, Canton R, Johansen HK, Hoffman L, Coenye T, Burgel PR, Davies JC.

    New concepts in antimicrobial resistance in cystic fibrosis respiratory infections

    JOURNAL OF CYSTIC FIBROSIS . 21(6): 937-945. Number of citations: 6

    [doi:10.1016/j.jcf.2022.10.005]

  • Moraleda C, Domínguez-Rodríguez S, Mesa JM, García-Sánchez P, de la Serna M, Alonso-Cadenas JA, Bermejo A, Sabrido G, Martínez-Campos L, González-Posada AF, Illán-Ramos M, Cobos-Carrascosa E, Ballesteros Á, Galán JC, Llorente F, Aguilera-Alonso D, Jiménez AB, Catalán P, Dahdouh E, Navarro I, Fernández-Garoz B, Mendoza P, Pérez-Jorge C, Cabezas-Fernández T, Blázquez-Gamero D, Rivas G, Gonzalez-Donapetry P, Sáez E, Fernández-Pinero J, Lucas-Fernández J, Pérez-Ramírez E, Merino P, Miragaya S, Lorente J, Iglesias I, Tagarro A.

    Oral saliva swab reverse transcription PCR for Covid-19 in the paediatric population

    ARCHIVES OF DISEASE IN CHILDHOOD . 107(11): 1051-1058. Number of citations: 2

    [doi:10.1136/archdischild-2021-323712]

  • Hernández-García M, García-Castillo M, Melo-Cristino J, Pinto MF, Gonçalves E, Alves V, Vieira AR, Ramalheira E, Sancho L, Diogo J, Ferreira R, Cruz H, Chaves C, Bou G, Cercenado E, Delgado-Valverde M, Oliver A, Pitart C, Rodríguez-Lozano J, Tormo N, Díaz-Regañón J, Pássaro L, Duarte J, Cantón R.

    In vitro activity of imipenem/relebactam against Pseudomonas aeruginosa isolates recovered from ICU patients in Spain and Portugal (SUPERIOR and STEP studies)

    The Journal of antimicrobial chemotherapy . 77(11): 3163-3172. Number of citations: 5

    [doi:10.1093/jac/dkac298]

  • Díaz-García J, Gómez A, Machado M, Alcalá L, Reigadas E, Sánchez-Carrillo C, Pérez-Ayala A, Gómez-García de la Pedrosa E, González-Romo F, Cuétara MS, García-Esteban C, Quiles-Melero I, Zurita ND, Muñoz-Algarra M, Durán-Valle MT, Sánchez-García A, Muñoz P, Escribano P, Guinea J.

    Blood and intra-abdominal Candida spp. from a multicentre study conducted in Madrid using EUCAST: emergence of fluconazole resistance in Candida parapsilosis, low echinocandin resistance and absence of Candida auris

    The Journal of antimicrobial chemotherapy . 77(11): 3102-3109. Number of citations: 11

    [doi:10.1093/jac/dkac288]

  • Pedraza R, Kieffer N, Guzmán-Puche J, Artacho MJ, Pitart C, Hernández-García M, Vila J, Cantón R, Martinez-Martinez L.

    Hidden dissemination of carbapenem-susceptible OXA-48-producing Proteus mirabilis.

    The Journal of antimicrobial chemotherapy . 77(11): 3009-3015.

    [doi:10.1093/jac/dkac267]

  • Pina-Coronado C, Martínez-Sobrino Á, Gutiérrez-Gálvez L, Del Caño R, Martínez-Periñán E, García-Nieto D, Rodríguez-Peña M, Luna M, Milán-Rois P, Castellanos M, Abreu M, Cantón R, Galán JC, Pineda T, Pariente F, Somoza Á, García-Mendiola T, Miranda R, Lorenzo E.

    Methylene Blue functionalized carbon nanodots combined with different shape gold nanostructures for sensitive and selective SARS-CoV-2 sensing

    SENSORS AND ACTUATORS B-CHEMICAL . 369: 132217-132217. Number of citations: 8

    [doi:10.1016/j.snb.2022.132217]

  • Gijón Cordero D, Castillo-Polo JA, Ruiz-Garbajosa P, Cantón R.

    Antibacterial spectrum of cefiderocol.

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 35 Suppl 2: 20-27. Number of citations: 2

    [doi:10.37201/req/s02.03.2022]

  • Ferrer R, Soriano A, Cantón R, Del Pozo JL, García-Vidal C, Garnacho-Montero J, Larrosa N, Rascado P, Salavert M, Pintado V, Giró-Perafita N, Badia X.

    A systematic literature review and expert consensus on risk factors associated to infection progression in adult patients with respiratory tract or rectal colonisation by carbapenem-resistant Gram-negative bacteria.

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 35(5): 455-467. Number of citations: 3

    [doi:10.37201/req/062.2022]

  • Gómez-Pavón J, González Del Castillo J, Martín-Delgado MC, Martín Sánchez FJ, Martínez-Sellés M, Molero García JM, Moreno Guillén S, Rodríguez-Artalejo FJ, Ruiz-Galiana J, Cantón R, De Lucas Ramos P, García-Botella A, García-Lledó A, Hernández-Sampelayo T, Bouza E.

    COVID-19: Some unresolved issues.

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 35(5): 421-434.

    [doi:10.37201/req/028.2022]

  • González Del Castillo J, Martín-Delgado MC, Martín Sánchez FJ, Martínez-Sellés M, Molero García JM, Moreno Guillén S, Rodríguez-Artalejo FJ, Ruiz-Galiana J, Cantón R, De Lucas Ramos P, García-Botella A, García-Lledó A, Hernández-Sampelayo T, Gómez-Pavón J, Bouza E.

    Lessons from COVID-19 for future disasters: an opinion paper

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 35(5): 444-454. Number of citations: 1

    [doi:10.37201/req/058.2022]

  • Gómez-Pavón J, González Del Castillo J, Martín-Delgado MC, Martín Sánchez FJ, Martínez-Sellés M, Molero García JM, MORENO GUILLÉN, SANTIAGO, Rodríguez Artalejo FJ, Ruiz-Galiana J, CANTÓN MORENO, RAFAEL.

    COVID-19: Some unresolved issues

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 35(5): 421-434.

    [doi:10.37201/req/028.2022.]

  • Antonelli A, Coppi M, Tellapragada C, Hasan B, Maruri A, Gijón D, Morecchiato F, de Vogel C, Verbon A, van Wamel W, Kragh KN, Frimodt-Møller N, Cantón R, Giske CG, Rossolini GM.

    Isothermal microcalorimetry vs checkerboard assay to evaluate in-vitro synergism of meropenem-amikacin and meropenem-colistin combinations against multi-drug-resistant Gram-negative pathogens

    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS . 60(4): 106668-106668. Number of citations: 4

    [doi:10.1016/j.ijantimicag.2022.106668]

  • Del Valle-Pérez R, Ballesteros Á, Calvo C, Sainz T, Mendez A, Grasa C, Molina PR, Mellado MJ, Sanz-Santaeufemia FJ, Herrero B, Calleja L, Soriano-Arandes A, Melendo S, Rincón-López E, Hernánz A, Epalza C, García-Baeza C, Rupérez-García E, Berzosa A, Ocaña A, Villarroya-Villalba A, Barrios A, Otheo E, Galán JC, Rodríguez MJ, Mesa JM, Domínguez-Rodríguez S, Moraleda C, Tagarro A.

    Comparison of pneumonia features in children caused by SARS-CoV-2 and other viral respiratory pathogens

    PEDIATRIC PULMONOLOGY . 57(10): 2374-2382. Number of citations: 2

    [doi:10.1002/ppul.26042]

  • Ruz-Caracuel I, Pian-Arias H, Corral Í, Carretero-Barrio I, Bueno-Sacristán D, Pérez-Mies B, García-Cosío M, Caniego-Casas T, Pizarro D, García-Narros MI, Piris-Villaespesa M, Pestaña D, de Pablo R, Galán JC, Masjuan J, Palacios J.

    Neuropathological findings in fatal COVID-19 and their associated neurological clinical manifestations

    Pathology . 54(6): 738-745. Number of citations: 7

    [doi:10.1016/j.pathol.2022.03.006]

  • Torres-Fernandez D, Jiménez de Ory S, Fortuny C, Sainz T, Falcón D, Bernal E, Jiménez MC, Vilasaró MN, Epalza C, Navarro M, Ramos JT, Holguín Á, Prieto L.

    Integrase inhibitors in children and adolescents: clinical use and resistance

    The Journal of antimicrobial chemotherapy . 77(10): 2784-2792. Number of citations: 1

    [doi:10.1093/jac/dkac259]