Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • López-Pintor JM, Martínez-García L, Maruri A, Menéndez B, Puerta T, Rodríguez C, González-Alba JM, Rodríguez-Domínguez M, Galán JC.

    Quantification of plasmid copy number as surrogate marker of virulence among different invasive and non-invasive genotypes of Chlamydia trachomatis

    DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE . 102(4): 115610-115610. Number of citations: 1

    [doi:10.1016/j.diagmicrobio.2021.115610]

  • Vargas JM, Moreno Mochi MP, López CG, Alarcón JA, Acosta N, Soria K, Nuñez JM, Villafañe S, Ramacciotti J, del Campo R, Jure MA.

    Impacto de un programa de vigilancia activa y medidas de control de infecciones sobre la incidencia de bacilos gram negativos resistentes a carbapenems en una unidad de cuidados intensivos.

    REV ARGENT MICROBIOL . 54(2): 134-142.

    [doi:10.1016/j.ram.2021.03.003]

  • Fluit AC, Bayjanov JR, Aguilar MD, Benaissa-Trouw B, Tunney MM, Westreenen MV, Meis JF, Elborn JS, Cantón R, Ekkelenkamp MB.

    Taxonomic position, antibiotic resistance and virulence factors of clinical Achromobacter isolates.

    Frontiers in Bioscience - Scholar . 14(2): 9-9.

    [doi:10.31083/j.fbs1402009]

  • Hernández-García M, Castillo-Polo JA, Cordero DG, Pérez-Viso B, García-Castillo M, Fuente JS, Morosini MI, Cantón R, Ruiz-Garbajosa P.

    Impact of ceftazidime-avibactam treatment in the emergence of novel KPC variants in ST307-Klebsiella pneumoniae high-risk clone and consequences for their routine detection.

    JOURNAL OF CLINICAL MICROBIOLOGY . 60(3): . Number of citations: 2

    [doi:10.1128/jcm.02245-21]

  • Giske CG, Turnidge J, Cantón R, Kahlmeter G.

    Update From The European Committee On Antimicrobial Suseptibility Testing (EUCAST).

    JOURNAL OF CLINICAL MICROBIOLOGY . 60(3): . Number of citations: 15

    [doi:10.1128/JCM.00276-21]

  • Hernández-García M, García-Castillo M, Ruiz-Garbajosa P, Bou G, Siller-Ruiz M, Pitart C, Gracia-Ahufinger I, Mulet X, Pascual Á, Tormo N, Cantón R.

    In vitro activity of cefepime-taniborbactam against carbapenemase producing Enterobacterales and Pseudomonas aeruginosa isolates recovered in Spain.

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 66(3): . Number of citations: 8

    [doi:10.1128/aac.02161-21]

  • Baquero F, del Campo R, Martínez JL.

    Interventions in Nicotinamide Adenine Dinucleotide Metabolism, the Intestinal Microbiota and Microcin Peptide Antimicrobials

    Frontiers in Molecular Biosciences . 9: 861603-861603. Number of citations: 1

    [doi:10.3389/fmolb.2022.861603]

  • Feito J, Contente D, Ponce-Alonso M, Díaz-Formoso L, Araújo C, Peña N, Borrero J, Gómez-Sala B, Del Campo R, Muñoz-Atienza E, Hernández PE, Cintas LM.

    Draft Genome Sequence of Lactococcus lactis Subsp. cremoris WA2-67: A Promising Nisin-Producing Probiotic Strain Isolated from the Rearing Environment of a Spanish Rainbow Trout (Oncorhynchus mykiss, Walbaum) Farm

    Microorganisms . 10(3): . Number of citations: 5

    [doi:10.3390/microorganisms10030521]

  • Pérez-Cobas AE, Baquero F, de Pablo R, Soriano MC, Coque TM.

    Altered Ecology of the Respiratory Tract Microbiome and Nosocomial Pneumonia

    FRONTIERS IN MICROBIOLOGY . 12: 709421-709421. Number of citations: 9

    [doi:10.3389/fmicb.2021.709421]

  • Ruiz-Galiana, Julian, de Lucas Ramos, Pilar, Garcia-Botella, Alejandra, Garcia-Lledo, Alberto, Gomez-Pavon, Javier, Gonzalez del Castillo, Juan, Hernandez-Sampelayo, Teresa, Cruz Martin-Delgado, Mari, Martin Sanchez, Francisco Javier, Martinez-Selles, Manuel, Molero Garcia, Jose Maria, Moreno Guillen, Santiago, Rodriguez-Artalejo, Fernando, Canton, Rafael, Bouza, Emilio.

    Persistence and viability of SARS-CoV-2 in primary infection and reinfections

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 35(1): 1-6. Number of citations: 3

    [doi:10.37201/req/129.2021]

  • de Lucas Ramos, Pilar, Garcia-Botella, Alejandra, Garcia-Lledo, Alberto, Gomez-Pavon, Javier, Gonzalez del Castillo, Juan, Hernandez-Sampelayo, Teresa, Cruz Martin-Delgado, Mari, Martin Sanchez, Francisco Javier, Martinez-Selles, Manuel, Molero Garcia, Jose Maria, Moreno Guillen, Santiago, Rodriguez-Artalejo, Fernando, Ruiz-Galiana, Julian, Canton, Rafael, Bouza, Emilio.

    Actions and attitudes on the immunized patients against SARS-CoV-2

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 35(1): 7-15. Number of citations: 1

    [doi:10.37201/req/131.2021]

  • van Hal SJ, Willems RJL, Gouliouris T, Ballard SA, Coque TM, Hammerum AM, Hegstad K, Pinholt M, Howden BP, Malhotra-Kumar S, Werner G, Yanagihara K, Earl AM, Raven KE, Corander J, Bowden R, Enterococcal Study Group.

    The interplay between community and hospital Enterococcus faecium clones within health-care settings: a genomic analysis.

    The Lancet. Microbe . 3(2): .

    [doi:10.1016/S2666-5247(21)00236-6]

  • Gill CM, Aktaþ E, Alfouzan W, Bourassa L, Brink A, Burnham CD, Canton R, Carmeli Y, Falcone M, Kiffer C, Marchese A, Martinez O, Pournaras S, Satlin MJ, Seifert H, Thabit AK, Thomson KS, Villegas MV, Nicolau DP.

    Multicenter, Prospective Validation of a Phenotypic Algorithm to Guide Carbapenemase Testing in Carbapenem-Resistant Pseudomonas aeruginosa Using the ERACE-PA Global Surveillance Program

    Open forum infectious diseases . 9(2): . Number of citations: 3

    [doi:10.1093/ofid/ofab617]

  • Cantón R, Barberán J, Linares M, Molero JM, Rodríguez-González-Moro JM, Salavert M, González Del Castillo J.

    Decalogue for the selection of oral antibiotics for lower respiratory tract infections.

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 35(1): 16-29. Number of citations: 1

    [doi:10.37201/req/172.2021]

  • Aranaz-Andrés JM, Chávez ACF, Laso AM, Abreu M, Núñez PM, Galán JC, Moreno RC.

    Analysis of the diagnostic accuracy of rapid antigenic tests for detection of SARS-CoV-2 in hospital outbreak situation

    EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES . 41(2): 1-8. Number of citations: 2

    [doi:10.1007/s10096-021-04346-8]

  • Caniego-Casas T, Martínez-García L, Alonso-Riaño M, Pizarro D, Carretero-Barrio I, Martínez-de-Castro N, Ruz-Caracuel I, de Pablo R, Saiz A, Royo RN, Santiago A, Rosas M, Rodríguez-Peralto JL, Pérez-Mies B, Galán JC, Palacios J.

    RNA SARS-CoV-2 Persistence in the Lung of Severe COVID-19 Patients: A Case Series of Autopsies.

    FRONTIERS IN MICROBIOLOGY . 13: 824967-824967. Number of citations: 4

    [doi:10.3389/fmicb.2022.824967]

  • Gato E, Anantharajah A, Arroyo MJ, Artacho MJ, Caballero JD, Candela A, Chudejová K, Constanso IP, Elías C, Fernández J, Jiménez J, Lumbreras P, Méndez G, Mulet X, Pérez-Palacios P, Rodríguez-Sánchez B, Cantón R, Hrabák J, Mancera L, Martínez-Martínez L, Oliver A, Pascual Á, Verroken A, Bou G, Oviaño M.

    Multicenter Performance Evaluation of MALDI-TOF MS for Rapid Detection of Carbapenemase Activity in Enterobacterales: The Future of Networking Data Analysis With Online Software

    FRONTIERS IN MICROBIOLOGY . 12: 789731-789731. Number of citations: 5

    [doi:10.3389/fmicb.2021.789731]

  • Rodríguez-Beltrán J, León-Sampedro R, Ramiro-Martínez P, de la Vega C, Baquero F, Levin BR, San Millán Á.

    Translational demand is not a major source of plasmid-associated fitness costs.

    PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES . 377(1842): 20200463-20200463. Number of citations: 4

    [doi:10.1098/rstb.2020.0463]