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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Rodríguez Díaz C, Lafuente-Gómez N, Coutinho C, Pardo D, Alarcón-Iniesta H, López-Valls M, Coloma R, Milán-Rois P, Domenech M, Abreu M, Cantón R, Galán JC, Bocanegra R, Campos LA, Miranda R, Castellanos M, Somoza Á.

    Development of colorimetric sensors based on gold nanoparticles for SARS-CoV-2 RdRp, E and S genes detection.

    Talanta . 243: 123393-123393. Number of citations: 6

    [doi:10.1016/j.talanta.2022.123393]

  • Alshammari, N, Alazmi, M, Alanazi, NA, Sulieman, AME, Veettil, VN, Ponce-Alonso, M.

    A Comparative Study on the Microbial Communities of Rhynchophorus ferrugineus (Red Palm Weevil)-Infected and Healthy Palm Trees

    ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING . 47(6): 6735-6746.

    [doi:10.1007/s13369-021-05979-9]

  • Valadés-Alcaraz A, Reinosa R, Holguín Á.

    HIV Transmembrane Glycoprotein Conserved Domains and Genetic Markers Across HIV-1 and HIV-2 Variants.

    FRONTIERS IN MICROBIOLOGY . 13: 855232-855232. Number of citations: 1

    [doi:10.3389/fmicb.2022.855232]

  • Rodríguez-Galet A, Rubio-Garrido M, Valadés-Alcaraz A, Rodríguez-Domínguez M, Galán JC, Ndarabu A, Reina G, Holguín A.

    Immune surveillance for six vaccinable pathogens using paired plasma and dried blood spots in HIV infected and uninfected children in Kinshasa.

    SCIENTIFIC REPORTS . 12(1): 7920-7920.

    [doi:10.1038/s41598-022-12052-4]

  • Fluit AC, Bayjanov JR, Aguilar MD, Cantón R, Elborn S, Tunney MM, Scharringa J, Benaissa-Trouw BJ, Ekkelenkamp MB.

    Taxonomic position, antibiotic resistance and virulence factor production by Stenotrophomonas isolates from patients with cystic fibrosis and other chronic respiratory infections.

    BMC MICROBIOLOGY . 22(1): 129-129. Number of citations: 1

    [doi:10.1186/s12866-022-02466-5]

  • López-Valls M, Escalona-Noguero C, Rodríguez-Díaz C, Pardo D, Castellanos M, Milán-Rois P, Martínez-Garay C, Coloma R, Abreu M, Cantón R, Galán JC, Miranda R, Somoza Á, Sot B.

    CASCADE: Naked eye-detection of SARS-CoV-2 using Cas13a and gold nanoparticles.

    ANALYTICA CHIMICA ACTA . 1205: 339749-339749. Number of citations: 8

    [doi:10.1016/j.aca.2022.339749]

  • Cortés A, Casado JL, Longo F, Serrano JJ, Saavedra C, Velasco H, Martin A, Chamorro J, Rosero D, Fernández M, Gion M, Martínez Jáñez N, Soria Rivas A, Alonso Gordoa T, Martínez Delfrade Í, Lage Y, López Miranda E, Olmedo ME, Reguera Puertas P, Gajate P, Molina Cerrillo J, Guerra Alia E, Fuentes Mateos R, Romero B, Rodríguez-Domínguez MJ, Vallejo A, Carrato A.

    Limited T cell response to SARS-CoV-2 mRNA vaccine among patients with cancer receiving different cancer treatments

    EUROPEAN JOURNAL OF CANCER . 166: 229-239. Number of citations: 12

    [doi:10.1016/j.ejca.2022.02.017]

  • Abichabki N, Zacharias LV, Moreira NC, Bellissimo-Rodrigues F, Moreira FL, Benzi JRL, Ogasawara TMC, Ferreira JC, Ribeiro CM, Pavan FR, Pereira LRL, Brancini GTP, Braga GÚL, Zuardi AW, Hallak JEC, Crippa JAS, Lanchote VL, Cantón R, Darini ALC, Andrade LN.

    Potential cannabidiol (CBD) repurposing as antibacterial and promising therapy of CBD plus polymyxin B (PB) against PB-resistant gram-negative bacilli

    SCIENTIFIC REPORTS . 12(1): 6454-6454. Number of citations: 11

    [doi:10.1038/s41598-022-10393-8]

  • Troyano-Hernáez P, Reinosa R, Holguín Á.

    HIV Capsid Protein Genetic Diversity Across HIV-1 Variants and Impact on New Capsid-Inhibitor Lenacapavir.

    FRONTIERS IN MICROBIOLOGY . 13: 854974-854974. Number of citations: 4

    [doi:10.3389/fmicb.2022.854974]

  • Do TT, Rodríguez-Beltran J, Cebrián-Sastre E, Rodríguez-Rojas A, Castañeda-García A, Blázquez J.

    Inactivation of a New Potassium Channel Increases Rifampicin Resistance and Induces Collateral Sensitivity to Hydrophilic Antibiotics in Mycobacterium smegmatis.

    ANTIBIOTICS-BASEL . 11(4): .

    [doi:10.3390/antibiotics11040509]

  • de Dios Caballero J, Cantón R, Ponce-Alonso M, García-Clemente MM, Gómez G de la Pedrosa E, López-Campos JL, Máiz L, Del Campo R, Martínez-García MÁ.

    The Human Mycobiome in Chronic Respiratory Diseases: Current Situation and Future Perspectives

    Microorganisms . 10(4): . Number of citations: 7

    [doi:10.3390/microorganisms10040810]

  • Martínez-Sanz J, Vivancos-Gallego MJ, Fernández-Felix BM, Muriel A, Pérez-Elías P, Uranga A, Romero B, Galán JC, Moreno S, Pérez-Elías MJ.

    An Easy-to-Implement Risk Score for Targeted Hepatitis C Virus Testing in the General Population.

    Microbiology spectrum . 10(2): . Number of citations: 1

    [doi:10.1128/spectrum.02286-21]

  • Del Caño R, García-Mendiola T, García-Nieto D, Álvaro R, Luna M, Iniesta HA, Coloma R, Diaz CR, Milán-Rois P, Castellanos M, Abreu M, Cantón R, Galán JC, Pineda T, Pariente F, Miranda R, Somoza Á, Lorenzo E.

    Amplification-free detection of SARS-CoV-2 using gold nanotriangles functionalized with oligonucleotides

    Microchimica Acta . 189(4): 171-171. Number of citations: 11

    [doi:10.1007/s00604-022-05272-y]

  • Canton R, Hamed K, Wiktorowicz T, Redder N, Jemmely N, Quevedo J, Santerre Henriksen A.

    In vitro activity of ceftobiprole and comparator antibiotics against contemporary European isolates (2016-19).

    Jac-Antimicrobial Resistance . 4(2): .

    [doi:10.1093/jacamr/dlac030]

  • Ekkelenkamp MB, Díez-Aguilar M, Tunney MM, Elborn JS, Fluit AC, Cantón R.

    Establishing Antimicrobial Susceptibility Testing Methods and Clinical Breakpoints for Inhaled Antibiotic Therapy

    Open forum infectious diseases . 9(4): . Number of citations: 3

    [doi:10.1093/ofid/ofac082]

  • García-Botella A, García-Lledó A, Gómez-Pavón J, González Del Castillo J, Hernández-Sampelayo T, Martín-Delgado MC, Martín Sánchez FJ, Martínez-Sellés M, Molero García JM, Moreno Guillén S, Rodríguez-Artalejo FJ, Ruiz-Galiana J, Cantón R, De Lucas Ramos P, Bouza E.

    Booster or additional vaccination doses in patients vaccinated against COVID-19.

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 35(2): 105-114. Number of citations: 6

    [doi:10.37201/req/149.2021]

  • García-Lledó A, Gómez-Pavón J, González Del Castillo J, Hernández-Sampelayo T, Martín-Delgado MC, Martín Sánchez FJ, Martínez-Sellés M, Molero García JM, Moreno Guillén S, Rodríguez-Artalejo FJ, Ruiz-Galiana J, Cantón R, De Lucas Ramos P, García-Botella A, Bouza E.

    Pharmacological treatment of COVID-19: an opinion paper.

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 35(2): 115-130. Number of citations: 30

    [doi:10.37201/req/158.2021]

  • Aguilera-Alonso D, Cantón R, Giske CG, Kahlmeter G, Kohns Vasconcelos M, Papan C, Turnidge J, ESPID-EUCAST Joint Task Force.

    Searching High and Low: Call for a Joint European Society for Paediatric Infectious Diseases-European Committee on Antimicrobial Susceptibility Testing Survey on Dosage of Antibacterial Agents in Children-Part One.

    PEDIATRIC INFECTIOUS DISEASE JOURNAL . 41(4): .

    [doi:10.1097/INF.0000000000003457]