Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Rodriguez-Beltran, Jeronimo, DelaFuente, Javier, Leon-Sampedro, Ricardo, MacLean, R. Craig, San Millan, Alvaro.

    Beyond horizontal gene transfer: the role of plasmids in bacterial evolution

    NATURE REVIEWS MICROBIOLOGY . 19(6): 347-359. Number of citations: 112

    [doi:10.1038/s41579-020-00497-1]

  • Calvo-Lerma J, Boon M, Hulst J, Colombo C, Asseiceira I, Garriga M, Masip E, Claes I, Bulfamante A, Janssens HM, Roca M, Vicente S, Fornés V, Zazzeron L, van Schijndel B, Woodcock S, Pereira L, de Boeck K, Ribes-Koninckx C.

    Change in Nutrient and Dietary Intake in European Children with Cystic Fibrosis after a 6-Month Intervention with a Self-Management mHealth Tool.

    Nutrients . 13(6): . Number of citations: 6

    [doi:10.3390/nu13061801]

  • Alonso-del Valle, Aida, Leon-Sampedro, Ricardo, Rodriguez-Beltran, Jeronimo, DelaFuente, Javier, Hernandez-Garcia, Marta, Ruiz-Garbajosa, Patricia, Canton, Rafael, Peña-Miller R, San Millan, Alvaro.

    Variability of plasmid fitness effects contributes to plasmid persistence in bacterial communities

    NATURE COMMUNICATIONS . 12(1): 2653-2653. Number of citations: 55

    [doi:10.1038/s41467-021-22849-y]

  • Martinez-Garcia, Laura, Rodriguez-Dominguez, Mario, Lejarraga, Clara, Rodríguez-Jiménez MC, Gonzalez-Alba, Jose Maria, Puerta, Teresa, Sanchez-Conde, Matilde, Hermida JM, Romero-Hernandez, Beatriz, Galan, Juan Carlos.

    The silent epidemic of lymphogranuloma venereum inside the COVID-19 pandemic in Madrid, Spain, March 2020 to February 2021

    Eurosurveillance . 26(18): . Number of citations: 5

    [doi:10.2807/1560-7917.ES.2021.26.18.2100422]

  • Alia-García E, Ponce-Alonso M, Saralegui C, Halperin A, Cortés MP, Baquero MR, Parra-Pecharromán D, Galeano J, del Campo R.

    Machine Learning Study in Caries Markers in Oral Microbiota from Monozygotic Twin Children

    DIAGNOSTICS . 11(5): . Number of citations: 1

    [doi:10.3390/diagnostics11050835]

  • Leon-Sampedro, Ricardo, DelaFuente, Javier, Diaz-Agero, Cristina, Crellen, Thomas, Musicha, Patrick, Rodriguez-Beltran, Jeronimo, de la Vega, Carmen, Hernandez-Garcia, Marta, Lopez-Fresnena, Nieves, Ruiz-Garbajosa, Patricia, Canton, Rafael, Cooper, Ben S., San Millan, Alvaro, R-GNOSIS WP5 Study Group.

    Pervasive transmission of a carbapenem resistance plasmid in the gut microbiota of hospitalized patients

    Nature Microbiology . 6(5): 606. Number of citations: 48

    [doi:10.1038/s41564-021-00879-y]

  • Merino P, Guinea J, Muñoz-Gallego I, González-Donapetry P, Galán JC, Antona N, Cilla G, Hernáez-Crespo S, Díaz-de Tuesta JL, Torrella AG, González-Romo F, Escribano P, Sánchez-Castellano MÁ, Sota-Busselo M, Delgado-Iribarren A, García J, Cantón R, Muñoz P, Folgueira MD, Cuenca-Estrella M, Oteo-Iglesias J, Medrano S, Pérez A, Galar A, Martínez-Expósito O, Alejo-Cancho I, Martín-Higuera MC, Rolo M, Estévez MJ, Bravo T, Vicente D, Montes M, Spanish Panbio™ COVID-19 validation group.

    Multicenter evaluation of the Panbio (TM) COVID-19 rapid antigen-detection test for the diagnosis of SARS-CoV-2 infection

    CLINICAL MICROBIOLOGY AND INFECTION . 27(5): 758-761. Number of citations: 48

    [doi:10.1016/j.cmi.2021.02.001]

  • Bou, German, Canton, Rafael, Martinez-Martinez, Luis, Navarro, David, Vila, Jordi.

    Fundamentals and implementation of Microbiological Diagnostic Stewardship Programs

    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA . 39(5): 248-251. Number of citations: 2

    [doi:10.1016/j.eimc.2020.02.019]

  • Rubio-Garrido, Marina, Reina, Gabriel, Ndarabu, Adolphe, Rodriguez-Galet, Ana, Valades-Alcaraz, Ana, Barquin, David, Carlos, Silvia, Holguin, Africa.

    High drug resistance levels could compromise the control of HIV infection in paediatric and adolescent population in Kinshasa, the Democratic Republic of Congo

    Plos One . 16(4): . Number of citations: 4

    [doi:10.1371/journal.pone.0248835]

  • Canton, Rafael.

    Current microbiological aspects of community respiratory infection beyond COVID-19

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 34(2): 81-92. Number of citations: 7

    [doi:10.37201/req/049.2021]

  • Ponce-Alonso, Manuel, Garcia-Fernandez, Sergio, del Campo, Rosa.

    Challenges of landscaping and modulation strategies in human intestinal microbiota

    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA . 39(4): 165-167. Number of citations: 1

    [doi:10.1016/j.eimc.2021.02.001]

  • Kragh, Kasper Norskov, Gijon, Desiree, Maruri, Ainhize, Antonelli, Alberto, Coppi, Marco, Kolpen, Mette, Crone, Stephanie, Tellapragada, Chaitanya, Hasan, Badrul, Radmer, Stine, de Vogel, Corne, van Wamel, Willem, Verbon, Annelies, Giske, Christian G., Rossolini, Gian Maria, Canton, Rafael, Frimodt-Moller, Niels.

    Effective antimicrobial combination in vivo treatment predicted with microcalorimetry screening

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 76(4): 1001-1009. Number of citations: 14

    [doi:10.1093/jac/dkaa543]

  • Diez-Aguilar, Maria, Hernandez-Garcia, Marta, Morosini, Maria-Isabel, Fluit, Ad, Tunney, Michael M., Huertas, Natalia, del Campo, Rosa, Obrecht, Daniel, Bernardini, Francesca, Ekkelenkamp, Miquel, Canton, Rafael.

    Murepavadin antimicrobial activity against and resistance development in cystic fibrosis Pseudomonas aeruginosa isolates

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 76(4): 984-992. Number of citations: 13

    [doi:10.1093/jac/dkaa529]

  • Ponce-Alonso, Manuel, Saez de la Fuente J, Rincon-Carlavilla, Angela, Moreno-Nunez, Paloma, Martinez-Garcia, Laura, Escudero-Sanchez, Rosa, Pintor, Rosario, Garcia-Fernandez, Sergio, Cobo, Javier.

    Impact of the coronavirus disease 2019 (COVID-19) pandemic on nosocomial Clostridioides difficile infection

    INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY . 42(4): 406-410. Number of citations: 56

    [doi:10.1017/ice.2020.454]

  • Canton, Rafael, Huarte, Rafael, Morata, Laura, Trillo-Mata, Jose Luis, Muñoz R, Gonzalez, Javier, Tort, Marina, Badia, Xavier.

    Determining the burden of infectious diseases caused by carbapenem-resistant gram-negative bacteria in Spain

    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA . 39(4): 179-183. Number of citations: 9

    [doi:10.1016/j.eimc.2020.04.009]

  • van Hal, Sebastiaan J., Willems, Rob J. L., Gouliouris, Theodore, Ballard, Susan A., Coque, Teresa M., Hammerum, Anette M., Hegstad, Kristin, Westh, Hendrik T., Howden, Benjamin P., Malhotra-Kumar, Surbhi, Werner, Guido, Yanagihara, Katsunori, Earl, Ashlee M., Raven, Katherine E., Corander, Jukka, Bowden, Rory, Enterococcal Group.

    The global dissemination of hospital clones of Enterococcus faecium

    GENOME MEDICINE . 13(1): 52-52. Number of citations: 20

    [doi:10.1186/s13073-021-00868-0]

  • Rodriguez-Bano, Jesus, Rossolini, Gian Maria, Schultsz, Constance, Tacconelli, Evelina, Murthy, Srinivas, Ohmagari, Norio, Holmes, Alison, Bachmann, Till, Goossens, Herman, Canton, Rafael, Roberts, Adam P, Henriques-Normark, Birgitta, Clancy, Cornelius J, Huttner, Benedikt, Fagerstedt, Patriq, Lahiri, Shawon, Kaushic, Charu, Hoffman, Steven J, Warren, Margo, Zoubiane, Ghada, Essack, Sabiha, Laxminarayan, Ramanan, Plant, Laura.

    Key considerations on the potential impacts of the COVID-19 pandemic on antimicrobial resistance research and surveillance.

    TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE . 115(10): 1122-1129. Number of citations: 48

    [doi:10.1093/trstmh/trab048]

  • Baquero, Fernando, Coque, Teresa M., Galan, Juan Carlos, Martinez, Jose L..

    The Origin of Niches and Species in the Bacterial World

    FRONTIERS IN MICROBIOLOGY . 12: 657986-657986. Number of citations: 31

    [doi:10.3389/fmicb.2021.657986]