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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Fernández-de-Bobadilla MD, Talavera-Rodríguez A, Chacón L, Baquero F, Coque TM, Lanza VF.

    PATO: Pangenome Analysis Toolkit

    Bioinformatics . 37(23): 4564-4566. Number of citations: 3

    [doi:10.1093/bioinformatics/btab697]

  • Gómez-Zorrilla S, Becerra-Aparicio F, López Montesinos I, Ruiz de Gopegui E, Grau I, Pintado V, Padilla B, Benito N, Boix-Palop L, Fariñas MC, Peñaranda M, Gamallo MR, Martinez JA, Morte-Romea E, Del Pozo JL, Durán-Jordá X, Díaz-Regañón J, López-Mendoza D, Cantón R, Oliver A, Ruiz-Garbajosa P, Horcajada JP, REIPI/GEIRAS-GEMARA SEIMC ITUBRAS-2 Group.

    A Large Multicenter Prospective Study of Community-Onset Healthcare Associated Bacteremic Urinary Tract Infections in the Era of Multidrug Resistance: Even Worse than Hospital Acquired Infections?

    Infectious diseases and therapy . 10(4): 2677-2699. Number of citations: 1

    [doi:10.1007/s40121-021-00537-0]

  • López-Pintor JM, García-Fernández S, Ponce-Alonso M, Sánchez-Díaz AM, Ruiz-Garbajosa P, Morosini MI, Cantón R.

    Etiology and antimicrobial susceptibility profiles of anaerobic bacteria isolated from clinical samples in a university hospital in Madrid, Spain

    Anaerobe . 72: 102446-102446. Number of citations: 1

    [doi:10.1016/j.anaerobe.2021.102446]

  • Pérez-Viso B, Aracil-Gisbert S, Coque TM, del Campo R, Ruiz-Garbajosa P, Cantón R.

    Evaluation of CHROMagar (TM)-Serratia agar, a new chromogenic medium for the detection and isolation of Serratia marcescens

    EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES . 40(12): 2593-2596.

    [doi:10.1007/s10096-021-04328-w]

  • Gill CM, Aktaþ E, Alfouzan W, Bourassa L, Brink A, Burnham CD, Canton R, Carmeli Y, Falcone M, Kiffer C, Marchese A, Martinez O, Pournaras S, Satlin M, Seifert H, Thabit AK, Thomson KS, Villegas MV, Nicolau DP, ERACE-PA Global Study Group.

    The ERACE-PA Global Surveillance Program: Ceftolozane/tazobactam and Ceftazidime/avibactam in vitro Activity against a Global Collection of Carbapenem-resistant Pseudomonas aeruginosa

    EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES . 40(12): 2533-2541. Number of citations: 16

    [doi:10.1007/s10096-021-04308-0]

  • Baquero F, Martínez JL, F Lanza V, Rodríguez-Beltrán J, Galán JC, San Millán A, Cantón R, Coque TM.

    Evolutionary Pathways and Trajectories in Antibiotic Resistance

    CLINICAL MICROBIOLOGY REVIEWS . 34(4): . Number of citations: 24

    [doi:10.1128/CMR.00050-19]

  • Bello S, Vengoechea JJ, Ponce-Alonso M, Figueredo AL, Mincholé E, Rezusta A, Gambó P, Pastor JM, Javier Galeano, del Campo R.

    Core Microbiota in Central Lung Cancer With Streptococcal Enrichment as a Possible Diagnostic Marker.

    ARCHIVOS DE BRONCONEUMOLOGIA . 57(11): 681-689.

    [doi:10.1016/j.arbr.2020.05.017]

  • Gómez M, Valverde A, del Campo R, Rodríguez JM, Maldonado-Barragán A.

    Phenotypic and Molecular Characterization of Commensal, Community-Acquired and Nosocomial Klebsiella spp.

    Microorganisms . 9(11): . Number of citations: 4

    [doi:10.3390/microorganisms9112344]

  • Hernández-García M, Díaz-Agero C, Pérez-Viso B, Sánchez AM, López-Fresneña N, Morosini MI, Ruiz-Garbajosa P, Cantón R.

    Implementation of contact isolation strategy for the containment of extended-spectrum ß-lactamase carriers in a University Hospital positively affects the epidemiology of carbapenemase-producing Enterobacterales.

    Enfermedades Infecciosas Y Microbiologia Clinica (english Ed.) . 39(9): 429-435.

    [doi:10.1016/j.eimce.2020.05.020]

  • Tedim AP, Lanza VF, Rodríguez CM, Freitas AR, Novais C, Peixe L, Baquero F, Coque TM.

    Fitness cost of vancomycin-resistant Enterococcus faecium plasmids associated with hospital infection outbreaks

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 76(11): 2757-2764. Number of citations: 1

    [doi:10.1093/jac/dkab249]

  • Baquero, Fernando.

    Threats of antibiotic resistance: an obliged reappraisal

    INTERNATIONAL MICROBIOLOGY . 24(4): 499-506. Number of citations: 27

    [doi:10.1007/s10123-021-00184-y]

  • Gioia, F, Filigheddu, M T, Corbella, L, Fernandez-Ruiz, M, Lopez-Medrano, F, Perez-Ayala, A, Aguado, J M, Fariñas C, Arnaiz, F, Calvo, J, Cifrian, J M, Gonzalez-Rico, C, Vidal, E, Torre-Cisneros, J, Ras, M, Perez, S, Sabe, N, Lopez-Soria, L, Rodriguez-Alvarez, R, Montejo, J M, Valerio, M, Machado, M, Munoz, P, Linares, L, Bodro, M, Moreno, A, Fernandez-Cruz, A, Canton, R, Moreno, S, Martin-Davila, P, Fortun, J.

    Invasive aspergillosis in solid organ transplantation: Diagnostic challenges and differences in outcome in a Spanish national cohort (Diaspersot study)

    Mycoses . 64(11): 1334-1345. Number of citations: 1

    [doi:10.1111/myc.13298]

  • Hernández-García M, Díaz-Agero C, Pérez-Viso B, Sánchez AM, López-Fresneña N, Morosini MI, Ruiz-Garbajosa P, Cantón R.

    Implementation of contact isolation strategy for the containment of extended-spectrum beta-lactamase carriers in a University Hospital positively affects the epidemiology of carbapenemase-producing Enterobacterales

    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA . 39(9): 429-435.

    [doi:10.1016/j.eimc.2020.05.013]

  • Bello, Salvador, Vengoechea, Jose J, Ponce-Alonso, Manuel, Figueredo, Ana L, Minchole, Elisa, Rezusta, Antonio, Gambo, Paula, Pastor, Juan Manuel, Javier Galeano, Del Campo, Rosa.

    Core Microbiota in Central Lung Cancer With Streptococcal Enrichment as a Possible Diagnostic Marker

    ARCHIVOS DE BRONCONEUMOLOGIA . 57(11): 681-689. Number of citations: 5

    [doi:10.1016/j.arbres.2020.05.034]

  • Baquero F, Martínez JL, Novais Â, Rodríguez-Beltrán J, Martínez-García L, Coque TM, Galán JC.

    Allogenous Selection of Mutational Collateral Resistance: Old Drugs Select for New Resistance Within Antibiotic Families

    FRONTIERS IN MICROBIOLOGY . 12: 757833-757833. Number of citations: 4

    [doi:10.3389/fmicb.2021.757833]

  • Gill CM, Aktaþ E, Alfouzan W, Bourassa L, Brink A, Burnham CA, Canton R, Carmeli Y, Falcone M, Kiffer C, Marchese A, Martinez O, Pournaras S, Seifert H, Thabit AK, Villegas MV, Westblade LF, Nicolau DP.

    Elevated MICs of Susceptible Anti-Pseudomonal Cephalosporins in Non-Carbapenemase-Producing, Carbapenem-Resistant Pseudomonas aeruginosa: Implications for Dose Optimization.

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 65(11): . Number of citations: 4

    [doi:10.1128/AAC.01204-21]

  • Ferrer-Gómez A, Pian-Arias H, Carretero-Barrio I, Navarro-Cantero A, Pestaña D, de Pablo R, Zamorano JL, Galán JC, Pérez-Mies B, Ruz-Caracuel I, Palacios J.

    Late Cardiac Pathology in Severe Covid-19. A Postmortem Series of 30 Patients

    Frontiers in Cardiovascular Medicine . 8: 748396-748396. Number of citations: 5

    [doi:10.3389/fcvm.2021.748396]

  • López MG, Chiner-Oms Á, García de Viedma D, Ruiz-Rodriguez P, Bracho MA, Cancino-Muñoz I, D'Auria G, de Marco G, García-González N, Goig GA, Gómez-Navarro I, Jiménez-Serrano S, Martinez-Priego L, Ruiz-Hueso P, Ruiz-Roldán L, Torres-Puente M, Alberola J, Albert E, Aranzamendi Zaldumbide M, Bea-Escudero MP, Boga JA, Bordoy AE, Canut-Blasco A, Carvajal A, Cilla Eguiluz G, Cordón Rodríguez ML, Costa-Alcalde JJ, de Toro M, de Toro Peinado I, Del Pozo JL, Duchêne S, Fernández-Pinero J, Fuster Escrivá B, Gimeno Cardona C, González Galán V, Gonzalo Jiménez N, Hernáez Crespo S, Herranz M, Lepe JA, López-Causapé C, López-Hontangas JL, Martín V, Martró E, Milagro Beamonte A, Montes Ros M, Moreno-Muñoz R, Navarro D, Navarro-Marí JM, Not A, Oliver A, Palop-Borrás B, Parra Grande M, Pedrosa-Corral I, Pérez González MC, Pérez-Lago L, Pérez-Ruiz M, Piñeiro Vázquez L, Rabella N, Rezusta A, Robles Fonseca L, Rodríguez-Villodres Á, Sanbonmatsu-Gámez S, Sicilia J, Soriano A, Tirado Balaguer MD, Torres I, Tristancho A, Marimón JM, SeqCOVID-Spain consortium, Coscolla M, González-Candelas F, Comas I.

    The first wave of the COVID-19 epidemic in Spain was associated with early introductions and fast spread of a dominating genetic variant.

    NATURE GENETICS . 53(10): 1405-1414. Number of citations: 20

    [doi:10.1038/s41588-021-00936-6]