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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Chevaliez, Stephane, Onelia, Francesco, Pacenti, Monia, Goldstein, Emily, Galan, Juan-Carlos, Martinez-Garcia, Laura, Vilas, Alba, Glass, Allison, Maree, Leana, Krugel, Maria, Ehret, Robert, Knechten, Heribert, Braun, Patrick, Naeth, Gudrun, Bonanzinga, Sara, Jackson, Kathy, Abravaya, Klara, Dhein, Jens, Huang, Shihai, Joseph, Ajith M., Lucic, Danijela, Marlowe, Natalia, Palm, Michael J., Pfeifer, Karin, Toolsie, Dan, Reinhardt, Birgit, Obermeier, Martin, Gunson, Rory.

    Multicenter clinical evaluation of alinity m HCV assay performance

    JOURNAL OF CLINICAL VIROLOGY . 129: 104531-104531. Number of citations: 10

    [doi:10.1016/j.jcv.2020.104531]

  • Frentrup, Martinique, Zhou, Zhemin, Steglich, Matthias, Meier-Kolthoff, Jan P., Göker M, Riedel, Thomas, Bunk, Boyke, Spröer C, Overmann, Jorg, Blaschitz, Marion, Indra, Alexander, von Müller L, Kohl, Thomas A., Niemann, Stefan, Seyboldt, Christian, Klawonn, Frank, Kumar, Nitin, Lawley, Trevor D., Garcia-Fernandez, Sergio, Canton, Rafael, Del Campo, Rosa, Zimmermann, Ortrud, Gross, Uwe, Achtman, Mark, Nübel U.

    A publicly accessible database for Clostridioides difficile genome sequences supports tracing of transmission chains and epidemics

    Microbial genomics . 6(8): . Number of citations: 17

    [doi:10.1099/mgen.0.000410]

  • Campos, Marcelino, San Millan, Alvaro, Sempere, Jose M., Lanza, Val F., Coque, Teresa M., Llorens, Carlos, Baquero, Fernando.

    Simulating the Influence of Conjugative-Plasmid Kinetic Values on the Multilevel Dynamics of Antimicrobial Resistance in a Membrane Computing Model

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 64(8): . Number of citations: 9

    [doi:10.1128/AAC.00593-20]

  • Turnidge, J., Kahlmeter, G., Canton, R., MacGowan, A., Giske, C. G., European Committee on Antimicrobial Susceptibility Testing.

    Daptomycin in the treatment of enterococcal bloodstream infections and endocarditis: a EUCAST position paper

    CLINICAL MICROBIOLOGY AND INFECTION . 26(8): 1039-1043. Number of citations: 26

    [doi:10.1016/j.cmi.2020.04.027]

  • Martinez-Sanz, Javier, Muriel, Alfonso, Vivancos-Gallego MJ, Galán JC, Romero, Beatriz, Rodríguez-Sagrado MÁ, Uranga, Almudena, Perez-Elias, Pilar, Barea, Rafael, Chamorro-Escobar, Clotilde, Herrero-Delgado, Margarita, Pérez-Elías MJ.

    Prevalence of HCV infection in a health area of Madrid (Spain): The first step towards microelimination

    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA . 38(7): 317-322. Number of citations: 1

    [doi:10.1016/j.eimc.2019.10.014]

  • Fortun, J., Buitrago, M. J., Gioia, F., Gómez-Gª de la Pedrosa E, Alvarez, M. E., Martin-Davila, P., Pintado, V, Cobeta, P., Martinez-Castro, N., Soriano, C., Moreno, I, Corral, S., Muñoz P, Moreno-Jimenez, G., Cuenca-Estrella, M., Moreno-Guillen, S..

    Roles of the multiplex real-time PCR assay and beta-D-glucan in a high-risk population for intra-abdominal candidiasis (IAC)

    Medical mycology . 58(6): 789-796. Number of citations: 6

    [doi:10.1093/mmy/myz123]

  • Ortiz-López FJ, Carretero-Molina, Daniel, Sanchez-Hidalgo, Marina, Martin, Jesus, Gonzalez, Ignacio, Roman-Hurtado, Fernando, de la Cruz, Mercedes, Garcia-Fernandez, Sergio, Reyes, Fernando, Deisinger JP, Müller A, Schneider, Tanja, Genilloud, Olga.

    Cacaoidin, First Member of the New Lanthidin RiPP Family

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION . 59(31): 12654-12658. Number of citations: 50

    [doi:10.1002/anie.202005187]

  • Santiago, Llipsy, Castro, Marta, Sanz-Pamplona, Rebeca, Garzon, Marcela, Ramirez-Labrada, Ariel, Tapia, Elena, Moreno, Victor, Layunta, Elena, Gil-Gomez, Gabriel, Garrido, Marta, Peña R, Lanuza, Pilar M., Comas, Laura, Jaime-Sanchez, Paula, Uranga-Murillo, Iratxe, del Campo, Rosa, Pelegrin, Pablo, Camerer, Eric, Martinez-Lostao, Luis, Muñoz G, Uranga, Jose A., Alcalde, Anabel, Galvez, Eva M., Ferrandez, Angel, Bird PI, Metkar, Sunil, Arias, Maykel A., Pardo, Julian.

    Extracellular Granzyme A Promotes Colorectal Cancer Development by Enhancing Gut Inflammation

    CELL REPORTS . 32(1): 107847-107847. Number of citations: 29

    [doi:10.1016/j.celrep.2020.107847]

  • Rodriguez-Beltran, Jeronimo, Sørum V, Toll-Riera, Macarena, de la Vega, Carmen, Peña-Miller R, San Millan, Alvaro.

    Genetic dominance governs the evolution and spread of mobile genetic elements in bacteria

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA . 117(27): 15755-15762. Number of citations: 31

    [doi:10.1073/pnas.2001240117]

  • Aranaz Andrés JM, Gea Velázquez de Castro MT, Vicente-Guijarro J, Beltrán Peribáñez J, García Haro M, Valencia-Martín JL, Bischofberger Valdés C, Grupo de Trabajo COVID-19 del Hospital Universitario Ramón y Cajal.

    [Masks as personal protective equipment in the COVID-19 pandemic: How, when and which should be used].

    Journal Of Healthcare Quality Research . 35(4): 245-252. Number of citations: 15

    [doi:10.1016/j.jhqr.2020.06.001]

  • Boon, M., Calvo-Lerma, J., Claes, I, Havermans, T., Asseiceira, I, Bulfamante, A., Garriga, M., Masip, E., van Schijndel BAM, Fornes, V, Barreto, C., Colombo, C., Crespo, P., Vicente, S., Janssens, H., Hulst, J., Witters, P., Nobili, R., Pereira, L., Ruperto, M., Van der Wiel, E., Mainz, J. G., De Boeck, K., Ribes-Koninckx, C..

    Use of a mobile application for self-management of pancreatic enzyme replacement therapy is associated with improved gastro-intestinal related quality of life in children with Cystic Fibrosis

    JOURNAL OF CYSTIC FIBROSIS . 19(4): 562-568. Number of citations: 17

    [doi:10.1016/j.jcf.2020.04.001]

  • Soldevila N, Toledo D, Ortiz de Lejarazu R, Tamames S, Castilla J, Astray J, Fernández MA, Martín V, Egurrola M, Morales Suárez-Varela M, Domínguez À.

    Effect of antiviral treatment in older patients hospitalized with confirmed influenza

    ANTIVIRAL RESEARCH . 178: 104785-104785. Number of citations: 2

    [doi:10.1016/j.antiviral.2020.104785]

  • Lopez-Campos, Jose Luis, Miravitlles, Marc, de la Rosa Carrillo, David, Canton, Rafael, Soler-Cataluna, Juan Jose, Martinez-Garcia, Miguel Angel.

    Current Challenges in Chronic Bronchial Infection in Patients with Chronic Obstructive Pulmonary Disease

    Journal Of Clinical Medicine . 9(6): . Number of citations: 17

    [doi:10.3390/jcm9061639]

  • Noumi, Emira, Merghni, Abderrahmen, Alreshidi, Mousa, Del Campo, Rosa, Adnan, Mohd, Haddad, Ons, De Feo, Vincenzo, Snoussi, Mejdi.

    Phenotypic and Genotypic Characterization with MALDI-TOF-MS Based Identification of Staphylococcus spp. Isolated from Mobile Phones with their Antibiotic Susceptibility, Biofilm Formation, and Adhesion Properties

    INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH . 17(11): . Number of citations: 12

    [doi:10.3390/ijerph17113761]

  • Perez-Losada, Marcos, Arenas, Miguel, Galán JC, Bracho MA, Hillung, Julia, Garcia-Gonzalez, Neris, Gonzalez-Candelas, Fernando.

    High-throughput sequencing (HTS) for the analysis of viral populations

    INFECTION GENETICS AND EVOLUTION . 80: 104208-104208. Number of citations: 26

    [doi:10.1016/j.meegid.2020.104208]

  • Lopez-Roa, P., Aznar, E., Cacho, J., Cogollos-Agruna, R., Domingo, D., García-Arata MI, Millan, R., Paez, M., Perez-Cecilia, E., Ruiz-Serrano, M. J., Simon, M., Tato, M., Toro, C., Valverde, J. F., Esteban, J..

    Epidemiology of Non-Tuberculous Mycobacteria isolated from clinical specimens in Madrid, Spain, from 2013 to 2017

    EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES . 39(6): 1089-1094. Number of citations: 10

    [doi:10.1007/s10096-020-03826-7]

  • Avendaño-Ortiz J, Rubio-Garrido, Marina, Lozano-Rodriguez, Roberto, del Romero, Jorge, Rodriguez, Carmen, Moreno, Santiago, Aguirre, Luis A., Holguin, Africa, Lopez-Collazo, Eduardo.

    Soluble PD-L1: a potential immune marker for HIV-1 infection and virological failure

    Medicine . 99(20): . Number of citations: 9

    [doi:10.1097/MD.0000000000020065]

  • Lopez-Alcalde, Jesus, Antequera Martin, Alba, Stallings, Elena, Muriel, Alfonso, Fernandez-Felix, Borja, Sola, Ivan, Del Campo, Rosa, Ponce-Alonso, Manuel, Gordo, Federico, Fidalgo, Pilar, Halperin, Ana Veronica, Alvarez-Diaz, Noelia, Madrid-Pascual, Olaya, Urrutia, Gerard, Zamora, Javier.

    Evaluation of the role of sex as a prognostic factor in critically ill adults with sepsis: systematic review protocol.

    BMJ open . 10(5): 35927-35927. Number of citations: 7

    [doi:10.1136/bmjopen-2019-035927]