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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Santiago, Llipsy, Castro, Marta, Sanz-Pamplona, Rebeca, Garzon, Marcela, Ramirez-Labrada, Ariel, Tapia, Elena, Moreno, Victor, Layunta, Elena, Gil-Gomez, Gabriel, Garrido, Marta, Peña R, Lanuza, Pilar M., Comas, Laura, Jaime-Sanchez, Paula, Uranga-Murillo, Iratxe, del Campo, Rosa, Pelegrin, Pablo, Camerer, Eric, Martinez-Lostao, Luis, Muñoz G, Uranga, Jose A., Alcalde, Anabel, Galvez, Eva M., Ferrandez, Angel, Bird PI, Metkar, Sunil, Arias, Maykel A., Pardo, Julian.

    Extracellular Granzyme A Promotes Colorectal Cancer Development by Enhancing Gut Inflammation

    CELL REPORTS . 32(1): 107847-107847. Number of citations: 29

    [doi:10.1016/j.celrep.2020.107847]

  • Rodriguez-Beltran, Jeronimo, Sørum V, Toll-Riera, Macarena, de la Vega, Carmen, Peña-Miller R, San Millan, Alvaro.

    Genetic dominance governs the evolution and spread of mobile genetic elements in bacteria

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA . 117(27): 15755-15762. Number of citations: 31

    [doi:10.1073/pnas.2001240117]

  • Aranaz Andrés JM, Gea Velázquez de Castro MT, Vicente-Guijarro J, Beltrán Peribáñez J, García Haro M, Valencia-Martín JL, Bischofberger Valdés C, Grupo de Trabajo COVID-19 del Hospital Universitario Ramón y Cajal.

    [Masks as personal protective equipment in the COVID-19 pandemic: How, when and which should be used].

    Journal Of Healthcare Quality Research . 35(4): 245-252. Number of citations: 15

    [doi:10.1016/j.jhqr.2020.06.001]

  • Boon, M., Calvo-Lerma, J., Claes, I, Havermans, T., Asseiceira, I, Bulfamante, A., Garriga, M., Masip, E., van Schijndel BAM, Fornes, V, Barreto, C., Colombo, C., Crespo, P., Vicente, S., Janssens, H., Hulst, J., Witters, P., Nobili, R., Pereira, L., Ruperto, M., Van der Wiel, E., Mainz, J. G., De Boeck, K., Ribes-Koninckx, C..

    Use of a mobile application for self-management of pancreatic enzyme replacement therapy is associated with improved gastro-intestinal related quality of life in children with Cystic Fibrosis

    JOURNAL OF CYSTIC FIBROSIS . 19(4): 562-568. Number of citations: 17

    [doi:10.1016/j.jcf.2020.04.001]

  • Soldevila N, Toledo D, Ortiz de Lejarazu R, Tamames S, Castilla J, Astray J, Fernández MA, Martín V, Egurrola M, Morales Suárez-Varela M, Domínguez À.

    Effect of antiviral treatment in older patients hospitalized with confirmed influenza

    ANTIVIRAL RESEARCH . 178: 104785-104785. Number of citations: 2

    [doi:10.1016/j.antiviral.2020.104785]

  • Lopez-Campos, Jose Luis, Miravitlles, Marc, de la Rosa Carrillo, David, Canton, Rafael, Soler-Cataluna, Juan Jose, Martinez-Garcia, Miguel Angel.

    Current Challenges in Chronic Bronchial Infection in Patients with Chronic Obstructive Pulmonary Disease

    Journal Of Clinical Medicine . 9(6): . Number of citations: 17

    [doi:10.3390/jcm9061639]

  • Noumi, Emira, Merghni, Abderrahmen, Alreshidi, Mousa, Del Campo, Rosa, Adnan, Mohd, Haddad, Ons, De Feo, Vincenzo, Snoussi, Mejdi.

    Phenotypic and Genotypic Characterization with MALDI-TOF-MS Based Identification of Staphylococcus spp. Isolated from Mobile Phones with their Antibiotic Susceptibility, Biofilm Formation, and Adhesion Properties

    INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH . 17(11): . Number of citations: 12

    [doi:10.3390/ijerph17113761]

  • Perez-Losada, Marcos, Arenas, Miguel, Galán JC, Bracho MA, Hillung, Julia, Garcia-Gonzalez, Neris, Gonzalez-Candelas, Fernando.

    High-throughput sequencing (HTS) for the analysis of viral populations

    INFECTION GENETICS AND EVOLUTION . 80: 104208-104208. Number of citations: 26

    [doi:10.1016/j.meegid.2020.104208]

  • Lopez-Roa, P., Aznar, E., Cacho, J., Cogollos-Agruna, R., Domingo, D., García-Arata MI, Millan, R., Paez, M., Perez-Cecilia, E., Ruiz-Serrano, M. J., Simon, M., Tato, M., Toro, C., Valverde, J. F., Esteban, J..

    Epidemiology of Non-Tuberculous Mycobacteria isolated from clinical specimens in Madrid, Spain, from 2013 to 2017

    EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES . 39(6): 1089-1094. Number of citations: 10

    [doi:10.1007/s10096-020-03826-7]

  • Avendaño-Ortiz J, Rubio-Garrido, Marina, Lozano-Rodriguez, Roberto, del Romero, Jorge, Rodriguez, Carmen, Moreno, Santiago, Aguirre, Luis A., Holguin, Africa, Lopez-Collazo, Eduardo.

    Soluble PD-L1: a potential immune marker for HIV-1 infection and virological failure

    Medicine . 99(20): . Number of citations: 9

    [doi:10.1097/MD.0000000000020065]

  • Lopez-Alcalde, Jesus, Antequera Martin, Alba, Stallings, Elena, Muriel, Alfonso, Fernandez-Felix, Borja, Sola, Ivan, Del Campo, Rosa, Ponce-Alonso, Manuel, Gordo, Federico, Fidalgo, Pilar, Halperin, Ana Veronica, Alvarez-Diaz, Noelia, Madrid-Pascual, Olaya, Urrutia, Gerard, Zamora, Javier.

    Evaluation of the role of sex as a prognostic factor in critically ill adults with sepsis: systematic review protocol.

    BMJ open . 10(5): 35927-35927. Number of citations: 7

    [doi:10.1136/bmjopen-2019-035927]

  • Guinea, Jesus, Arendrup, Maiken C., Canton, Rafael, Canton, Emilia, Garcia-Rodriguez, Julio, Gomez, Ana, de la Pedrosa EGG, Hare, Rasmus K., Orden, Beatriz, Sanguinetti, Maurizio, Peman, Javier, Posteraro, Brunella, Ruiz-Gaitan, Alba, Parisi, Gabriella, Da Matta, Daniel Archimedes, Colombo, Arnaldo L., Sanchez-Carrillo, Carlos, Reigadas, Elena, Muñoz P, Escribano, Pilar.

    Genotyping Reveals High Clonal Diversity and Widespread Genotypes of Candida Causing Candidemia at Distant Geographical Areas

    FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY . 10: 166-166. Number of citations: 17

    [doi:10.3389/fcimb.2020.00166]

  • Castanheira, Sonia, Lopez-Escarpa, David, Pucciarelli MG, Cestero, Juan J., Baquero, Fernando, Garcia-del Portillo, Francisco.

    An alternative penicillin-binding protein involved in Salmonella relapses following ceftriaxone therapy

    EBioMedicine . 55: 102771-102771. Number of citations: 11

    [doi:10.1016/j.ebiom.2020.102771]

  • Lorenzo, Irene, Fernandez-de-Larrea, Nerea, Michel, Angelika, Romero, Beatriz, Lope, Virginia, Bessa, Xavier, Moreno, Victor, Martin, Vicente, Amiano, Pilar, Castilla, Jesus, Tardon, Adonina, Dierssen-Sotos, Trinidad, Peiro, Rosana, Diaz-Santos, Marian, Navarro, Carmen, Jimenez-Moleon, Jose J., Butt, Julia, Barricarte, Aurelio, Ruiz, Irune, Molina-de-la-Torre, Antonio J., Casabonne, Delphine, Perez-Gomez, Beatriz, Kogevinas, Manolis, del Campo, Rosa, de Sanjose, Silvia, Pollan, Marina, Waterboer, Tim, Aragones, Nuria.

    Reply to: Comment to: Helicobacter pylori seroprevalence in Spain: influence of adult and childhood sociodemographic factors

    EUROPEAN JOURNAL OF CANCER PREVENTION . 29(3): 279-280.

    [doi:10.1097/CEJ.0000000000000518]

  • Maechler, Friederike, Schwab, Frank, Hansen, Sonja, Fankhauser, Carolina, Harbarth, Stephan, Huttner, Benedikt D., Diaz-Agero, Cristina, Lopez, Nieves, Canton, Rafael, Ruiz-Garbajosa, Patricia, Blok, Hetty, Bonten, Marc J., Kloosterman, Fieke, Schotsman, Joost, Cooper, Ben S., Behnke, Michael, Golembus, Jennifer, Kola, Axel, Gastmeier, Petra, R-GNOSIS WP5 study group.

    Contact isolation versus standard precautions to decrease acquisition of extended-spectrum beta-lactamase-producing Enterobacterales in non-critical care wards: a cluster-randomised crossover trial

    LANCET INFECTIOUS DISEASES . 20(5): 575-584. Number of citations: 25

    [doi:10.1016/S1473-3099(19)30626-7]

  • Chamorro-Tojeiro, Sandra, Gonzalez-Sarria, Ander, Pedrosa EGG, Buitrago, Maria J., Lopez-Velez, Rogelio.

    Acute pulmonary paracoccidioidomycosis in a traveler to Mexico

    JOURNAL OF TRAVEL MEDICINE . 27(4): . Number of citations: 1

    [doi:10.1093/jtm/taaa018]

  • Freitas, Ana R., Novais, Carla, Coque, Teresa M., Peixe, Luisa.

    Comment on: Emergence of plasmid-mediated oxazolidinone resistance gene poxtA from CC17 Enterococcus faecium of pig origin

    The Journal of antimicrobial chemotherapy . 75(5): 1358-1359. Number of citations: 1

    [doi:10.1093/jac/dkz432]

  • Blasco, Lucia, Ambroa, Anton, Trastoy, Rocio, Bleriot, Ines, Moscoso, Miriam, Fernandez-Garcia, Laura, Perez-Nadales, Elena, Fernandez-Cuenca, Felipe, Torre-Cisneros, Julian, Oteo-Iglesias, Jesus, Oliver, Antonio, Canton, Rafael, Kidd, Tim, Navarro, Ferran, Miro, Elisenda, Pascual, Alvaro, Bou, German, Martinez-Martinez, Luis, Tomas, Maria.

    In vitro and in vivo efficacy of combinations of colistin and different endolysins against clinical strains of multi-drug resistant pathogens

    SCIENTIFIC REPORTS . 10(1): 7163-7163. Number of citations: 44

    [doi:10.1038/s41598-020-64145-7]