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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • García-Fernández S, García-Castillo M, Ruiz-Garbajosa P, Morosini MI, Bala Y, Zambardi G, Cantón R.

    Performance of CHROMID® Colistin R agar, a new chromogenic medium for screening of colistin-resistant Enterobacterales.

    DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE . 93(1): 1-4. Number of citations: 9

    [doi:10.1016/j.diagmicrobio.2018.07.008]

  • Botelho J, Roberts AP, León-Sampedro R, Grosso F, Peixe L.

    Carbapenemases on the move: it's good to be on ICEs.

    MOBILE DNA . 9: 37-37. Number of citations: 25

    [doi:10.1186/s13100-018-0141-4]

  • Diab-Cáceres L, Girón-Moreno RM, Pastor-Sanz MT, Quintana-Gallego E, Delgado-Pecellín I, Blanco-Aparicio M, Maiz L, García-Clemente MM, Luna-Paredes C, Mondéjar-López P, Ruiz-de-Valbuena M, Fernández O, Barrio M, González M, López-Neyra A, Cols-I-Roig M, Palou-Rotger A, Gómez-de-Terreros-Caro FJ.

    Compassionate Use of Lumacaftor/Ivacaftor in Cystic Fibrosis: Spanish Experience.

    ARCHIVOS DE BRONCONEUMOLOGIA . 54(12): 614-618. Number of citations: 5

    [doi:10.1016/j.arbres.2018.05.004]

  • Morte E, Tolmos M, Halperin A, Morosini MI, Cantón R, Hermida JM.

    Early prosthetic endocarditis caused by Stenotrophomonas maltophilia.

    Medecine et maladies infectieuses . 48(8): 543-546. Number of citations: 2

    [doi:10.1016/j.medmal.2018.09.004]

  • San Millan A, Toll-Riera M, Qi Q, Betts A, Hopkinson RJ, McCullagh J, MacLean RC.

    Integrative analysis of fitness and metabolic effects of plasmids in Pseudomonas aeruginosa PAO1.

    ISME JOURNAL . 12(12): 3014-3024. Number of citations: 44

    [doi:10.1038/s41396-018-0224-8]

  • San Millan A.

    Evolution of Plasmid-Mediated Antibiotic Resistance in the Clinical Context.

    TRENDS IN MICROBIOLOGY . 26(12): 978-985. Number of citations: 119

    [doi:10.1016/j.tim.2018.06.007]

  • Blázquez-Garrido RM, Cuchí-Burgos E, Martín-Salas C, Ruiz-Garbajosa P.

    Microbiological monitoring of medical devices after cleaning, disinfection and sterilisation.

    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA . 36(10): 657-661.

    [doi:10.1016/j.eimc.2017.09.012]

  • Tagarro A, Martín MD, Del-Amo N, Sanz-Rosa D, Rodríguez Md PhD M, Galán Md PhD JC, Otheo E.

    Hyponatremia in children with pneumonia rarely means SIADH.

    PAEDIATRICS & CHILD HEALTH . 23(7): 126-133. Number of citations: 8

    [doi:10.1093/pch/pxy003]

  • Kidd TJ, Canton R, Ekkelenkamp M, Johansen HK, Gilligan P, LiPuma JJ, Bell SC, Elborn JS, Flume PA, VanDevanter DR, Waters VJ, Antimicrobial Resistance in Cystic Fibrosis International Working Group.

    Defining antimicrobial resistance in cystic fibrosis.

    JOURNAL OF CYSTIC FIBROSIS . 17(6): 696-704. Number of citations: 44

    [doi:10.1016/j.jcf.2018.08.014]

  • Hernández-García M, León-Sampedro R, Pérez-Viso B, Morosini MI, López-Fresneña N, Diaz-Agero C, Coque TM, Ruiz-Garbajosa P, Cantón R.

    First Report of an OXA-48- and CTX-M-213-Producing Kluyvera Species Clone Recovered from Patients Admitted in a University Hospital in Madrid, Spain.

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 62(11): . Number of citations: 15

    [doi:10.1128/AAC.01238-18]

  • Merino I, Hernández-García M, Turrientes MC, Pérez-Viso B, López-Fresneña N, Diaz-Agero C, Maechler F, Fankhauser-Rodriguez C, Kola A, Schrenzel J, Harbarth S, Bonten M, Gastmeier P, Canton R, Ruiz-Garbajosa P, R-GNOSIS Study Group.

    Emergence of ESBL-producing Escherichia coli ST131-C1-M27 clade colonizing patients in Europe.

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 73(11): 2973-2980. Number of citations: 34

    [doi:10.1093/jac/dky296]

  • Hernández-García M, Pérez-Viso B, Carmen Turrientes M, Díaz-Agero C, López-Fresneña N, Bonten M, Malhotra-Kumar S, Ruiz-Garbajosa P, Cantón R.

    Characterization of carbapenemase-producing Enterobacteriaceae from colonized patients in a university hospital in Madrid, Spain, during the R-GNOSIS project depicts increased clonal diversity over time with maintenance of high-risk clones.

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 73(11): 3039-3043. Number of citations: 27

    [doi:10.1093/jac/dky284]

  • Russo A, Falcone M, Gutiérrez-Gutiérrez B, Calbo E, Almirante B, Viale PL, Oliver A, Ruiz-Garbajosa P, Gasch O, Gozalo M, Pitout J, Akova M, Peña C, Cisneros JM, Hernández-Torres A, Farcomeni A, Prim N, Origüen J, Bou G, Tacconelli E, Tumbarello M, Hamprecht A, Karaiskos I, de la Calle C, Pérez F, Schwaber MJ, Bermejo J, Lowman W, Hsueh PR, Mora-Rillo M, Rodriguez-Gomez J, Souli M, Bonomo RA, Paterson DL, Carmeli Y, Pascual A, Rodríguez-Baño J, Venditti M, REIPI/ESGBIS/INCREMENT investigators.

    Predictors of outcome in patients with severe sepsis or septic shock due to extended-spectrum ß-lactamase-producing Enterobacteriaceae.

    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS . 52(5): 577-585. Number of citations: 23

    [doi:10.1016/j.ijantimicag.2018.06.018]

  • Russo N, Caggia C, Pino A, Coque TM, Arioli S, Randazzo CL.

    Enterococcus spp. in Ragusano PDO and Pecorino Siciliano cheese types: A snapshot of their antibiotic resistance distribution.

    FOOD AND CHEMICAL TOXICOLOGY . 120: 277-286. Number of citations: 19

    [doi:10.1016/j.fct.2018.07.023]

  • Graells T, Hernández-García M, Pérez-Jové J, Guy L, Padilla E.

    Legionella pneumophila recurrently isolated in a Spanish hospital: Two years of antimicrobial resistance surveillance.

    ENVIRONMENTAL RESEARCH . 166: 638-646. Number of citations: 12

    [doi:10.1016/j.envres.2018.06.045]

  • Bordallo-Cardona MÁ, Escribano P, Marcos-Zambrano LJ, Díaz-García J, de la Pedrosa EG, Cantón R, Bouza E, Guinea J.

    Low and constant micafungin concentrations may be sufficient to lead to resistance mutations in FKS2 gene of Candida glabrata.

    Medical mycology . 56(7): 903-906. Number of citations: 10

    [doi:10.1093/mmy/myx124]

  • Blázquez J, Rodríguez-Beltrán J, Matic I.

    Antibiotic-Induced Genetic Variation: How It Arises and How It Can Be Prevented.

    ANNU REV MICROBIOL . 72: 209-230. Number of citations: 44

    [doi:10.1146/annurev-micro-090817-062139]

  • Bender JK, Cattoir V, Hegstad K, Sadowy E, Coque TM, Westh H, Hammerum AM, Schaffer K, Burns K, Murchan S, Novais C, Freitas AR, Peixe L, Del Grosso M, Pantosti A, Werner G.

    Update on prevalence and mechanisms of resistance to linezolid, tigecycline and daptomycin in enterococci in Europe: Towards a common nomenclature.

    DRUG RESISTANCE UPDATES . 40: 25-39. Number of citations: 93

    [doi:10.1016/j.drup.2018.10.002]