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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Prieto LM, Fernández McPhee C, Rojas P, Mazariegos D, Muñoz E, Mellado MJ, Holguín Á, Navarro ML, González-Tomé MI, Ramos JT, Madrid Cohort of HIV-Infected Mother-Infant Pairs.

    Pregnancy outcomes in perinatally HIV-infected young women in Madrid, Spain: 2000-2015.

    Plos One . 12(8): . Number of citations: 9

    [doi:10.1371/journal.pone.0183558]

  • Raoult D, Baquero F.

    Rewiring Microbiology and Infection.

    CLINICAL INFECTIOUS DISEASES . 65(suppl_1): . Number of citations: 3

    [doi:10.1093/cid/cix345]

  • Baquero F.

    Basic Sciences Fertilizing Clinical Microbiology and Infection Management.

    CLINICAL INFECTIOUS DISEASES . 65(suppl_1): . Number of citations: 2

    [doi:10.1093/cid/cix350]

  • López-Causapé C, Sommer LM, Cabot G, Rubio R, Ocampo-Sosa AA, Johansen HK, Figuerola J, Cantón R, Kidd TJ, Molin S, Oliver A.

    Evolution of the Pseudomonas aeruginosa mutational resistome in an international Cystic Fibrosis clone.

    SCIENTIFIC REPORTS . 7(1): 5555-5555. Number of citations: 82

    [doi:10.1038/s41598-017-05621-5]

  • Moore NM, Cantón R, Carretto E, Peterson LR, Sautter RL, Traczewski MM, Carba-R Study Team.

    Rapid Identification of Five Classes of Carbapenem Resistance Genes Directly from Rectal Swabs by Use of the Xpert Carba-R Assay.

    JOURNAL OF CLINICAL MICROBIOLOGY . 55(7): 2268-2275. Number of citations: 33

    [doi:10.1128/JCM.00137-17]

  • Chacón L, Mateos ML, Holguín Á.

    Relevance of cutoff on a 4th generation ELISA performance in the false positive rate during HIV diagnostic in a low HIV prevalence setting.

    JOURNAL OF CLINICAL VIROLOGY . 92: 11-13. Number of citations: 25

    [doi:10.1016/j.jcv.2017.04.014]

  • Gutiérrez-Gutiérrez B, Salamanca E, de Cueto M, Hsueh PR, Viale P, Paño-Pardo JR, Venditti M, Tumbarello M, Daikos G, Cantón R, Doi Y, Tuon FF, Karaiskos I, Pérez-Nadales E, Schwaber MJ, Azap ÖK, Souli M, Roilides E, Pournaras S, Akova M, Pérez F, Bermejo J, Oliver A, Almela M, Lowman W, Almirante B, Bonomo RA, Carmeli Y, Paterson DL, Pascual A, Rodríguez-Baño J, REIPI/ESGBIS/INCREMENT Investigators.

    Effect of appropriate combination therapy on mortality of patients with bloodstream infections due to carbapenemase-producing Enterobacteriaceae (INCREMENT): a retrospective cohort study.

    The Lancet. Infectious diseases . 17(7): 726-734. Number of citations: 275

    [doi:10.1016/S1473-3099(17)30228-1]

  • Calvo-Lerma J, Hulst JM, Asseiceira I, Claes I, Garriga M, Colombo C, Fornés V, Woodcock S, Martins T, Boon M, Ruperto M, Walet S, Speziali C, Witters P, Masip E, Barreto C, de Boeck K, Ribes-Koninckx C, MyCyFAPP Project.

    Nutritional status, nutrient intake and use of enzyme supplements in paediatric patients with Cystic Fibrosis; a European multicentre study with reference to current guidelines.

    JOURNAL OF CYSTIC FIBROSIS . 16(4): 510-518. Number of citations: 24

    [doi:10.1016/j.jcf.2017.03.005]

  • Yao Y, Lazaro-Perona F, Falgenhauer L, Valverde A, Imirzalioglu C, Dominguez L, Cantón R, Mingorance J, Chakraborty T.

    Insights into a Novel blaKPC-2-Encoding IncP-6 Plasmid Reveal Carbapenem-Resistance Circulation in Several Enterobacteriaceae Species from Wastewater and a Hospital Source in Spain.

    FRONTIERS IN MICROBIOLOGY . 8: 1143-1143. Number of citations: 32

    [doi:10.3389/fmicb.2017.01143]

  • González-García A, Fortún J, Elorza Navas E, Martín-Dávila P, Tato M, Gómez-Mampaso E, Moreno S.

    The changing epidemiology of tuberculosis in a Spanish tertiary hospital (1995-2013).

    Medicine . 96(26): . Number of citations: 8

    [doi:10.1097/MD.0000000000007219]

  • Fernández de Larrea-Baz N, Michel A, Romero B, Pérez-Gómez B, Moreno V, Martín V, Dierssen-Sotos T, Jiménez-Moleón JJ, Castilla J, Tardón A, Ruiz I, Peiró R, Tejada A, Chirlaque MD, Butt JA, Olmedo-Requena R, Gómez-Acebo I, Linares P, Boldo E, Castells A, Pawlita M, Castaño-Vinyals G, Kogevinas M, de Sanjosé S, Pollán M, Del Campo R, Waterboer T, Aragonés N.

    Helicobacter pylori Antibody Reactivities and Colorectal Cancer Risk in a Case-control Study in Spain.

    FRONTIERS IN MICROBIOLOGY . 8: 888-888. Number of citations: 14

    [doi:10.3389/fmicb.2017.00888]

  • Arias M, COBO ÁLVAREZ, MARTA, Jaime-Sánchez P, Pasto J, Marijuan P, Pardo J, Rezusta A, CAMPO MORENO, ROSA MARÍA DEL.

    Gut microbiota and systemic inflammation changes after bread consumption: The ingredients and the processing influence

    JOURNAL OF FUNCTIONAL FOODS . 32: 98-105. Number of citations: 13

    [doi:10.1016/j.jff.2017.02.023]

  • Caballero JD, Girón R, Del Campo R, Prados C, Barrio MI, Salcedo A, Cantón R.

    Antibiotic prescription patterns in Spanish cystic fibrosis patients: results from a national multicenter study.

    FARMACIA HOSPITALARIA . 41(3): 391-400.

    [doi:10.7399/fh.2017.41.3.10746]

  • Tam VH, Chang KT, Zhou J, Ledesma KR, Phe K, Gao S, Van Bambeke F, Sánchez-Díaz AM, Zamorano L, Oliver A, Cantón R.

    Determining ß-lactam exposure threshold to suppress resistance development in Gram-negative bacteria.

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 72(5): 1421-1428. Number of citations: 44

    [doi:10.1093/jac/dkx001]

  • Delgado-Valverde M, Valiente-Mendez A, Torres E, Almirante B, Gómez-Zorrilla S, Borrell N, Aller-García AI, Gurgui M, Almela M, Sanz M, Bou G, Martínez-Martínez L, Cantón R, Antonio Lepe J, Causse M, Gutiérrez-Gutiérrez B, Pascual Á, Rodríguez-Baño J, REIPI/GEIH-SEIMC BACTERAEMIA-MIC Group.

    MIC of amoxicillin/clavulanate according to CLSI and EUCAST: discrepancies and clinical impact in patients with bloodstream infections due to Enterobacteriaceae.

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 72(5): 1478-1487. Number of citations: 16

    [doi:10.1093/jac/dkw562]

  • Moles L, Gómez M, Jiménez E, Bustos G, de Andrés J, Melgar A, Escuder D, Fernández L, Del Campo R, Rodríguez JM.

    Bacterial Diversity of the Gastric Content of Preterm Infants during Their First Month of Life at the Hospital.

    Frontiers in nutrition . 4: 12-12. Number of citations: 11

    [doi:10.3389/fnut.2017.00012]

  • Bordallo-Cardona MA, Marcos-Zambrano LJ, Gómez G de la Pedrosa E, Escribano P, Bouza E, Guinea J, Cantón R.

    Fluconazole-containing agar Sabouraud dextrose plates are not useful when screening for susceptibility in Candida albicans.

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 30(2): 127-130.

  • Freitas AR, Sousa C, Novais C, Silva L, Ramos H, Coque TM, Lopes J, Peixe L.

    Rapid detection of high-risk Enterococcus faecium clones by matrix-assisted laser desorption ionization time-of-flight mass spectrometry.

    DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE . 87(4): 299-307. Number of citations: 11

    [doi:10.1016/j.diagmicrobio.2016.12.007]