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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Calvo-Lerma J, Hulst JM, Asseiceira I, Claes I, Garriga M, Colombo C, Fornés V, Woodcock S, Martins T, Boon M, Ruperto M, Walet S, Speziali C, Witters P, Masip E, Barreto C, de Boeck K, Ribes-Koninckx C, MyCyFAPP Project.

    Nutritional status, nutrient intake and use of enzyme supplements in paediatric patients with Cystic Fibrosis; a European multicentre study with reference to current guidelines.

    JOURNAL OF CYSTIC FIBROSIS . 16(4): 510-518. Number of citations: 24

    [doi:10.1016/j.jcf.2017.03.005]

  • Yao Y, Lazaro-Perona F, Falgenhauer L, Valverde A, Imirzalioglu C, Dominguez L, Cantón R, Mingorance J, Chakraborty T.

    Insights into a Novel blaKPC-2-Encoding IncP-6 Plasmid Reveal Carbapenem-Resistance Circulation in Several Enterobacteriaceae Species from Wastewater and a Hospital Source in Spain.

    FRONTIERS IN MICROBIOLOGY . 8: 1143-1143. Number of citations: 32

    [doi:10.3389/fmicb.2017.01143]

  • González-García A, Fortún J, Elorza Navas E, Martín-Dávila P, Tato M, Gómez-Mampaso E, Moreno S.

    The changing epidemiology of tuberculosis in a Spanish tertiary hospital (1995-2013).

    Medicine . 96(26): . Number of citations: 8

    [doi:10.1097/MD.0000000000007219]

  • Fernández de Larrea-Baz N, Michel A, Romero B, Pérez-Gómez B, Moreno V, Martín V, Dierssen-Sotos T, Jiménez-Moleón JJ, Castilla J, Tardón A, Ruiz I, Peiró R, Tejada A, Chirlaque MD, Butt JA, Olmedo-Requena R, Gómez-Acebo I, Linares P, Boldo E, Castells A, Pawlita M, Castaño-Vinyals G, Kogevinas M, de Sanjosé S, Pollán M, Del Campo R, Waterboer T, Aragonés N.

    Helicobacter pylori Antibody Reactivities and Colorectal Cancer Risk in a Case-control Study in Spain.

    FRONTIERS IN MICROBIOLOGY . 8: 888-888. Number of citations: 14

    [doi:10.3389/fmicb.2017.00888]

  • Arias M, COBO ÁLVAREZ, MARTA, Jaime-Sánchez P, Pasto J, Marijuan P, Pardo J, Rezusta A, CAMPO MORENO, ROSA MARÍA DEL.

    Gut microbiota and systemic inflammation changes after bread consumption: The ingredients and the processing influence

    JOURNAL OF FUNCTIONAL FOODS . 32: 98-105. Number of citations: 13

    [doi:10.1016/j.jff.2017.02.023]

  • Caballero JD, Girón R, Del Campo R, Prados C, Barrio MI, Salcedo A, Cantón R.

    Antibiotic prescription patterns in Spanish cystic fibrosis patients: results from a national multicenter study.

    FARMACIA HOSPITALARIA . 41(3): 391-400.

    [doi:10.7399/fh.2017.41.3.10746]

  • Tam VH, Chang KT, Zhou J, Ledesma KR, Phe K, Gao S, Van Bambeke F, Sánchez-Díaz AM, Zamorano L, Oliver A, Cantón R.

    Determining ß-lactam exposure threshold to suppress resistance development in Gram-negative bacteria.

    The Journal of antimicrobial chemotherapy . 72(5): 1421-1428. Number of citations: 44

    [doi:10.1093/jac/dkx001]

  • Delgado-Valverde M, Valiente-Mendez A, Torres E, Almirante B, Gómez-Zorrilla S, Borrell N, Aller-García AI, Gurgui M, Almela M, Sanz M, Bou G, Martínez-Martínez L, Cantón R, Antonio Lepe J, Causse M, Gutiérrez-Gutiérrez B, Pascual Á, Rodríguez-Baño J, REIPI/GEIH-SEIMC BACTERAEMIA-MIC Group.

    MIC of amoxicillin/clavulanate according to CLSI and EUCAST: discrepancies and clinical impact in patients with bloodstream infections due to Enterobacteriaceae.

    The Journal of antimicrobial chemotherapy . 72(5): 1478-1487. Number of citations: 16

    [doi:10.1093/jac/dkw562]

  • Moles L, Gómez M, Jiménez E, Bustos G, de Andrés J, Melgar A, Escuder D, Fernández L, Del Campo R, Rodríguez JM.

    Bacterial Diversity of the Gastric Content of Preterm Infants during Their First Month of Life at the Hospital.

    Frontiers in nutrition . 4: 12-12. Number of citations: 11

    [doi:10.3389/fnut.2017.00012]

  • Bordallo-Cardona MA, Marcos-Zambrano LJ, Gómez G de la Pedrosa E, Escribano P, Bouza E, Guinea J, Cantón R.

    Fluconazole-containing agar Sabouraud dextrose plates are not useful when screening for susceptibility in Candida albicans.

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 30(2): 127-130.

  • Freitas AR, Sousa C, Novais C, Silva L, Ramos H, Coque TM, Lopes J, Peixe L.

    Rapid detection of high-risk Enterococcus faecium clones by matrix-assisted laser desorption ionization time-of-flight mass spectrometry.

    DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE . 87(4): 299-307. Number of citations: 11

    [doi:10.1016/j.diagmicrobio.2016.12.007]

  • Tedim AP, Lanza VF, Manrique M, Pareja E, Ruiz-Garbajosa P, Cantón R, Baquero F, Coque TM, Tobes R.

    Complete Genome Sequences of Isolates of Enterococcus faecium Sequence Type 117, a Globally Disseminated Multidrug-Resistant Clone.

    Genome announcements . 5(13): .

    [doi:10.1128/genomeA.01553-16]

  • Rojas Sánchez P, Prieto L, Jiménez De Ory S, Fernández Cooke E, Navarro ML, Ramos JT, Holguín Á, Madrid Cohort of HIV-1 Infected Children and Adolescents Integrated in the Paedi.

    Impact of lopinavir-ritonavir exposure in HIV-1 infected children and adolescents in Madrid, Spain during 2000-2014.

    Plos One . 12(3): . Number of citations: 6

    [doi:10.1371/journal.pone.0173168]

  • Calvo-Lerma J, Martinez-Jimenez CP, Lázaro-Ramos JP, Andrés A, Crespo-Escobar P, Stav E, Schauber C, Pannese L, Hulst JM, Suárez L, Colombo C, Barreto C, de Boeck K, Ribes-Koninckx C, MyCyFAPP.

    Innovative approach for self-management and social welfare of children with cystic fibrosis in Europe: development, validation and implementation of an mHealth tool (MyCyFAPP).

    BMJ open . 7(3): . Number of citations: 22

    [doi:10.1136/bmjopen-2016-014931]

  • Carrillo-Salinas FJ, Mestre L, Mecha M, Feliú A, Del Campo R, Villarrubia N, Espejo C, Montalbán X, Álvarez-Cermeño JC, Villar LM, Guaza C.

    Gut dysbiosis and neuroimmune responses to brain infection with Theiler's murine encephalomyelitis virus.

    SCIENTIFIC REPORTS . 7: 44377-44377. Number of citations: 29

    [doi:10.1038/srep44377]

  • SANCHEZ VALENZUELA, ANTONIO JESUS, RIPOLL GONZALEZ, AIDA, TURRIENTES LÓPEZ, MARÍA CARMEN, MORALES BARTOLOMÉ, EVA, RODRIGUEZ BAÑOS, MERCEDES, Mariona Bustamante, LOPEZ ESPINOSA, MARÍA JOSÉ, Sabrina Llopd, Loreto Santa-Marina, Ana Jiménez-Zabalae, MORENO BOFARULL, ANA, CANTÓN MORENO, RAFAEL, Jordi Sunyerc,, COQUE GONZÁLEZ, MARÍA TERESA, BAQUERO MOCHALES, FERNANDO.

    Copper Resistance in Aerobic Intestinal Bacteria from Children with Different Levels of Copper-Exposure

    Journal of Environment and Health Science . 3(1): 1-13.

    [doi:10.15436/2378-6841.17.1219]

  • Carvalho I, Del Campo R, Sousa M, Silva N, Carrola J, Marinho C, Santos T, Carvalho S, Nóvoa M, Quaresma M, Pereira JE, Cobo M, Igrejas G, Poeta P.

    Antimicrobial-resistant Escherichia coli and Enterococcus spp. isolated from Miranda donkey (Equus asinus): an old problem from a new source with a different approach.

    JOURNAL OF MEDICAL MICROBIOLOGY . 66(2): 191-202.

    [doi:10.1099/jmm.0.000423]

  • García-Fernández S, Hernández-García M, Valverde A, Ruiz-Garbajosa P, Morosini MI, Cantón R.

    CHROMagar mSuperCARBA performance in carbapenem-resistant Enterobacteriaceae isolates characterized at molecular level and routine surveillance rectal swab specimens.

    DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE . 87(3): 207-209. Number of citations: 10

    [doi:10.1016/j.diagmicrobio.2016.11.014]