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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Díez-Aguilar M, Morisini MI, Köksal E, Oliver A, Ekkelenkamp M, Cantón R.

    Use of Calgary and Microfluidic BioFlux Systems To Test the Activity of Fosfomycin and Tobramycin Alone and in Combination against Cystic Fibrosis Pseudomonas aeruginosa Biofilms.

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 62(1): . Number of citations: 30

    [doi:10.1128/AAC.01650-17]

  • Oliva J, Delgado-Sanz C, Larrauri A, Spanish Influenza Surveillance System.

    Estimating the burden of seasonal influenza in Spain from surveillance of mild and severe influenza disease, 2010-2016.

    Influenza and Other Respiratory Viruses . 12(1): 161-170. Number of citations: 45

    [doi:10.1111/irv.12499]

  • Costa-de-Oliveira S, Teixeira-Santos R, Silva AP, Pinho E, Mergulhão P, Silva-Dias A, Marques N, Martins-Oliveira I, Rodrigues AG, Paiva JA, Cantón R, Pina-Vaz C.

    Potential Impact of Flow Cytometry Antimicrobial Susceptibility Testing on the Clinical Management of Gram-Negative Bacteremia Using the FASTinov Kit.

    Frontiers in Microbiology . 8: 2455-2455. Number of citations: 27

    [doi:10.3389/fmicb.2017.02455]

  • Sánchez-Diener I, Zamorano L, López-Causapé C, Cabot G, Mulet X, Peña C, Del Campo R, Cantón R, Doménech-Sánchez A, Martínez-Martínez L, Arcos SC, Navas A, Oliver A.

    Interplay among Resistance Profiles, High-Risk Clones, and Virulence in the Caenorhabditis elegans Pseudomonas aeruginosa Infection Model.

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 61(12): . Number of citations: 44

    [doi:10.1128/AAC.01586-17]

  • Vielva L, de Toro M, Lanza VF, de la Cruz F.

    PLACNETw: a web-based tool for plasmid reconstruction from bacterial genomes.

    BIOINFORMATICS . 33(23): 3796-3798. Number of citations: 103

    [doi:10.1093/bioinformatics/btx462]

  • Cantón R, Gómez G de la Pedrosa E.

    Economic impact of rapid diagnostic methods in Clinical Microbiology: Price of the test or overall clinical impact.

    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA . 35(10): 659-666. Number of citations: 10

    [doi:10.1016/j.eimc.2017.09.005]

  • Freitas AR, Elghaieb H, León-Sampedro R, Abbassi MS, Novais C, Coque TM, Hassen A, Peixe L.

    Detection of optrA in the African continent (Tunisia) within a mosaic Enterococcus faecalis plasmid from urban wastewaters.

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 72(12): 3245-3251. Number of citations: 63

    [doi:10.1093/jac/dkx321]

  • Merino I, Porter SB, Johnston BD, Clabots C, Shaw E, Horcajada JP, Cantón R, Ruiz-Garbajosa P, Johnson JR, ITUBRAS-GEIH group.

    Virulence genes and subclone status as markers of experimental virulence in a murine sepsis model among Escherichia coli sequence type 131 clinical isolates from Spain.

    PLoS One . 12(11): . Number of citations: 7

    [doi:10.1371/journal.pone.0188838]

  • Baquero F, Martínez JL.

    Interventions on Metabolism: Making Antibiotic-Susceptible Bacteria.

    mBio . 8(6): . Number of citations: 27

    [doi:10.1128/mBio.01950-17]

  • López-Sanromán A, Rodríguez de Santiago E, Cobo Reinoso J, Del Campo Moreno R, Foruny Olcina JR, García Fernández S, García García de Paredes A, Aguilera Castro L, Ferre Aracil C, Albillos Martínez A.

    Results of the implementation of a multidisciplinary programme of faecal microbiota transplantation by colonoscopy for the treatment of recurrent Clostridium difficile infection.

    Gastroenterologia y Hepatologia . 40(9): 605-614. Number of citations: 4

    [doi:10.1016/j.gastrohep.2017.03.004]

  • Harris PNA, Pezzani MD, Gutiérrez-Gutiérrez B, Viale P, Hsueh PR, Ruiz-Garbajosa P, Venditti M, Tumbarello M, Navarro-Francisco C, Calbo E, Akova M, Giamarellou H, Oliver A, Almirante B, Gasch O, Martínez-Martínez L, Schwaber MJ, Daikos G, Pitout J, Peña C, Hernández-Torres A, Doi Y, Pérez F, Tuon FF, Tacconelli E, Carmeli Y, Bonomo RA, Pascual Á, Paterson DL, Rodríguez-Baño J, ESGBIS/REIPI/INCREMENT group.

    Geographical variation in therapy for bloodstream infections due to multidrug-resistant Enterobacteriaceae: a post-hoc analysis of the INCREMENT study.

    International Journal of Antimicrobial Agents . 50(5): 664-672. Number of citations: 7

    [doi:10.1016/j.ijantimicag.2017.08.005]

  • Levin BR, Baquero F, Ankomah PP, McCall IC.

    Phagocytes, Antibiotics, and Self-Limiting Bacterial Infections.

    TRENDS IN MICROBIOLOGY . 25(11): 878-892. Number of citations: 48

    [doi:10.1016/j.tim.2017.07.005]

  • Baquero F.

    Transmission as a basic process in microbial biology. Lwoff Award Prize Lecture.

    FEMS MICROBIOLOGY REVIEWS . 41(6): 816-827. Number of citations: 13

    [doi:10.1093/femsre/fux042]

  • Rodríguez-Domínguez M, González-Alba JM, Puerta T, Martínez-García L, Menéndez B, Cantón R, Romero JD, Galán JC.

    Spread of a new Chlamydia trachomatis variant from men who have sex with men to the heterosexual population after replacement and recombination in ompA and pmpH genes.

    CLINICAL MICROBIOLOGY AND INFECTION . 23(10): 761-766. Number of citations: 6

    [doi:10.1016/j.cmi.2017.03.009]

  • Fernández de Larrea-Baz N, Pérez-Gómez B, Michel A, Romero B, Lope V, Pawlita M, Fernández-Villa T, Moreno V, Martín V, Willhauck-Fleckenstein M, López-Abente G, Castilla J, Fernández-Tardón G, Dierssen-Sotos T, Santibáñez M, Peiró R, Jiménez-Moleón JJ, Navarro C, Castaño-Vinyals G, Kogevinas M, Pollán M, de Sanjosé S, Del Campo R, Waterboer T, Aragonés N.

    Helicobacter pylori serological biomarkers of gastric cancer risk in the MCC-Spain case-control Study.

    Cancer Epidemiology . 50(Pt A): 76-84. Number of citations: 14

    [doi:10.1016/j.canep.2017.08.002]

  • Rojas Sánchez P, Cobos A, Navaro M, Ramos JT, Pagán I, Holguín Á.

    Impact of Clinical Parameters in the Intrahost Evolution of HIV-1 Subtype B in Pediatric Patients: A Machine Learning Approach.

    Genome Biology and Evolution . 9(10): 2715-2726. Number of citations: 5

    [doi:10.1093/gbe/evx193]

  • de Dios Caballero J, Vida R, Cobo M, Máiz L, Suárez L, Galeano J, Baquero F, Cantón R, Del Campo R.

    Individual Patterns of Complexity in Cystic Fibrosis Lung Microbiota, Including Predator Bacteria, over a 1-Year Period.

    mBio . 8(5): . Number of citations: 46

    [doi:10.1128/mBio.00959-17]

  • Aguilera A, Navarro D, Rodríguez Frias F, Viciana I, Martínez-Sapiña AM, Rodríguez MJ, Martró E, Del Carmen Lozano M, Coletta E, Cardeñoso L, Suárez A, Trigo M, Rodríguez-Granjer J, Montiel N, de la Iglesia A, Alados JC, Vegas C, Bernal S, Fernández-Cuenca F, Pena MJ, Reina G, García-Bujalance S, Echevarria MJ, Benítez L, Pérez-Castro S, Ocete D, García-Arata I, Guerrero C, Rodríguez-Iglesias M, Casas P, García F.

    Prevalence and distribution of hepatitis C virus genotypes in Spain during the 2000-2015 period (the GEHEP 005 study).

    JOURNAL OF VIRAL HEPATITIS . 24(9): 725-732. Number of citations: 24

    [doi:10.1111/jvh.12700]