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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

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Only original articles, editorials, guidelines.

  • Tiddens HA, De Boeck K, Clancy JP, Fayon M, H G M A, Bresnik M, Derchak A, Lewis SA, Oermann CM, ALPINE study investigators.

    Open label study of inhaled aztreonam for Pseudomonas eradication in children with cystic fibrosis: The ALPINE study

    JOURNAL OF CYSTIC FIBROSIS . 14(1): 111-119. Number of citations: 40

    [doi:10.1016/j.jcf.2014.06.003]

  • Megías MC, Albarrán OG, Vasco PG, Ferreiro AL, Carro LM.

    Influence of macrolides, nutritional support and respiratory therapies in diabetes and normal glucose tolerance in cystic fibrosis. A retrospective analysis of a cohort of adult and younger patients

    DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS . 9(1): 1-6. Number of citations: 3

    [doi:10.1016/j.dsx.2014.09.016]

  • Máiz L, Vendrell M, Olveira C, Girón R, Nieto R, Martínez-García MÁ.

    Prevalence and Factors Associated with Isolation of Aspergillus and Candida from Sputum in Patients with Non-Cystic Fibrosis Bronchiectasis

    Respiration . 89(5): 396-403. Number of citations: 36

    [doi:10.1159/000381289]

  • Lopez, Y., Tato, M., Espinal, P., Garcia-Alonso, F., Gargallo-Viola, D., Canton, R., Vila, J..

    In vitro selection of mutants resistant to ozenoxacin compared with levofloxacin and ciprofloxacin in Gram-positive cocci

    The Journal of antimicrobial chemotherapy . 70(1): 57-61. Number of citations: 11

    [doi:10.1093/jac/dku375]

  • Oggioni MR, Coelho JR, Furi L, Knight DR, Viti C, Orefici G, Martinez JL, Freitas AT, Coque TM, Morrissey I, BIOHYPO consortium.

    Significant Differences Characterise the Correlation Coefficients between Biocide and Antibiotic Susceptibility Profiles in Staphylococcus aureus

    CURRENT PHARMACEUTICAL DESIGN . 21(16): 2054-2057. Number of citations: 22

    [doi:10.2174/1381612821666150310103238]

  • Prieto LM, González-Tomé MI, Muñoz E, Fernández-Ibieta M, Soto B, Álvarez A, Navarro ML, Roa MÁ, Beceiro J, de José MI, Olabarrieta I, Lora D, Ramos JT, Madrid Cohort of HIV-Infected Mother-Infant Pairs.

    Birth defects in a cohort of infants born to HIV-infected women in Spain, 2000-2009.

    BMC INFECTIOUS DISEASES . 14: 700-700. Number of citations: 6

    [doi:10.1186/s12879-014-0700-3]

  • Caballero Jde D, Del Campo R, Tato M, Gómez G de la Pedrosa E, Cobo M, López-Causapé C, Gómez-Mampaso E, Oliver A, Cantón R.

    Microbiological diagnostic procedures for respiratory cystic fibrosis samples in Spain: towards standard of care practices

    BMC MICROBIOLOGY . 14(1): 335-335. Number of citations: 7

    [doi:10.1186/s12866-014-0335-y]

  • de Been M, Lanza VF, de Toro M, Scharringa J, Dohmen W, Du Y, Hu J, Lei Y, Li N, Tooming-Klunderud A, Heederik DJ, Fluit AC, Bonten MJ, Willems RJ, de la Cruz F, van Schaik W.

    Dissemination of Cephalosporin Resistance Genes between Escherichia coli Strains from Farm Animals and Humans by Specific Plasmid Lineages

    PLOS GENETICS . 10(12): . Number of citations: 208

    [doi:10.1371/journal.pgen.1004776]

  • Cantón R, Canut A, Morosini MI, Oliver A.

    Breakpoints for carbapenemase-producing Enterobacteriaceae: is the problem solved?

    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA . 32 Suppl 4: 33-40.

    [doi:10.1016/S0213-005X(14)70172-7]

  • Lanza VF, de Toro M, Garcillán-Barcia MP, Mora A, Blanco J, Coque TM, de la Cruz F.

    Plasmid Flux in Escherichia coli ST131 Sublineages, Analyzed by Plasmid Constellation Network (PLACNET), a New Method for Plasmid Reconstruction from Whole Genome Sequences

    PLOS GENETICS . 10(12): . Number of citations: 106

    [doi:10.1371/journal.pgen.1004766]

  • García-Descalzo L, García-López E, Alcázar A, Baquero F, Cid C.

    Proteomic analysis of the adaptation to warming in the Antarctic bacteria Shewanella frigidimarina.

    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS . 1844(12): 2229-2240. Number of citations: 14

    [doi:10.1016/j.bbapap.2014.08.006]

  • Vergara A, Zboromyrska Y, Mosqueda N, Morosini MI, García-Fernández S, Roca I, Cantón R, Marco F, Vila J.

    Evaluation of a Loop-Mediated Isothermal Amplification-Based Methodology To Detect Carbapenemase Carriage in Acinetobacter Clinical Isolates

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 58(12): 7538-7540. Number of citations: 19

    [doi:10.1128/AAC.03870-14]

  • del Campo R, Garriga M, Pérez-Aragón A, Guallarte P, Lamas A, Máiz L, Bayón C, Roy G, Cantón R, Zamora J, Baquero F, Suárez L.

    Improvement of digestive health and reduction in proteobacterial populations in the gut microbiota of cystic fibrosis patients using a Lactobacillus reuteri probiotic preparation: a double blind prospective study.

    JOURNAL OF CYSTIC FIBROSIS . 13(6): 716-722. Number of citations: 74

    [doi:10.1016/j.jcf.2014.02.007]

  • Fortún J, Meije Y, Buitrago MJ, Gago S, Bernal-Martinez L, Pemán J, Pérez M, Gómez-G Pedrosa E, Madrid N, Pintado V, Martín-Dávila P, Cobo J, Fresco G, Moreno S, Cuenca-Estrella M.

    Clinical validation of a multiplex real-time PCR assay for detection of invasive candidiasis in intensive care unit patients

    The Journal of antimicrobial chemotherapy . 69(11): 3134-3141. Number of citations: 44

    [doi:10.1093/jac/dku225]

  • Fischer J, Rodríguez I, Baumann B, Guiral E, Beutin L, Schroeter A, Kaesbohrer A, Pfeifer Y, Helmuth R, Guerra B.

    bla(CTX-M-15)-carrying Escherichia coli and Salmonella isolates from livestock and food in Germany

    The Journal of antimicrobial chemotherapy . 69(11): 2951-2958. Number of citations: 39

    [doi:10.1093/jac/dku270]

  • Lamas A, Máiz L, Ruiz de Valbuena M, González-Casbas JM, Suárez L.

    Subcutaneous implant with etonogestrel (Implanon (R)) for catamenial exacerbations in a patient with cystic fibrosis: a case report

    BMC PULMONARY MEDICINE . 14: 165-165. Number of citations: 3

    [doi:10.1186/1471-2466-14-165]

  • Stegger M, Wirth T, Andersen PS, Skov RL, De Grassi A, Simões PM, Tristan A, Petersen A, Aziz M, Kiil K, Cirkovic I, Udo EE, del Campo R, Vuopio-Varkila J, Ahmad N, Tokajian S, Peters G, Schaumburg F, Olsson-Liljequist B, Givskov M, Driebe EE, Vigh HE, Shittu A, Ramdani-Bougessa N, Rasigade JP, Price LB, Vandenesch F, Larsen AR, Laurent F.

    Origin and Evolution of European Community-Acquired Methicillin-Resistant Staphylococcus aureus

    Mbio . 5(5): . Number of citations: 70

    [doi:10.1128/mBio.01044-14]

  • Turrientes MC, González-Alba JM, del Campo R, Baquero MR, Cantón R, Baquero F, Galán JC.

    Recombination blurs phylogenetic groups routine assignment in Escherichia coli: setting the record straight.

    Plos One . 9(8): . Number of citations: 23

    [doi:10.1371/journal.pone.0105395]