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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Tacconelli E, Cataldo MA, Dancer SJ, De Angelis G, Falcone M, Frank U, Kahlmeter G, Pan A, Petrosillo N, Rodríguez-Baño J, Singh N, Venditti M, Yokoe DS, Cookson B, European Society of Clinical Microbiology.

    ESCMID guidelines for the management of the infection control measures to reduce transmission of multidrug-resistant Gram-negative bacteria in hospitalized patients

    CLINICAL MICROBIOLOGY AND INFECTION . 20(1, SI): 1-55. Number of citations: 457

    [doi:10.1111/1469-0691.12427]

  • López-Vicente J, Rodríguez-Alcalde D, Hernández-Villalba L, Moreno-Sánchez D, Lumbreras-Cabrera M, Barros-Aguado C, Galán JC.

    Proctitis as the clinical presentation of lymphogranuloma venereum, a re-emerging disease in developed countries.

    REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS . 106(1): 59-62. Number of citations: 17

    [doi:10.4321/S1130-01082014000100011]

  • Ripoll A, Galán JC, Rodríguez C, Tormo N, Gimeno C, Baquero F, Martínez-Martínez L, Cantón R.

    Detection of resistance to beta-lactamase inhibitors in strains with CTX-M beta-lactamases: a multicenter external proficiency study using a well-defined collection of Escherichia coli strains.

    JOURNAL OF CLINICAL MICROBIOLOGY . 52(1): 122-129. Number of citations: 12

    [doi:10.1128/JCM.02340-13]

  • Mateos-Lindemann ML, Diez-Aguilar M, Galdamez AL, Galán JC, Moreno A, Pérez-Gracia MT.

    Patients infected with HIV are at high-risk for hepatitis E virus infection in Spain

    JOURNAL OF MEDICAL VIROLOGY . 86(1): 71-74. Number of citations: 29

    [doi:10.1002/jmv.23804]

  • López Y, Tato M, Espinal P, Garcia-Alonso F, Gargallo-Viola D, Cantón R, Vila J.

    In Vitro Activity of Ozenoxacin against Quinolone-Susceptible and Quinolone-Resistant Gram-Positive Bacteria

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 57(12): 6389-6392. Number of citations: 25

    [doi:10.1128/AAC.01509-13]

  • Voets GM, Leverstein-van Hall MA, Kolbe-Busch S, van der Zanden A, Church D, Kaase M, Grisold A, Upton M, Cloutman-Green E, Cantón R, Friedrich AW, Fluit AC.

    International Multicenter Evaluation of the DiversiLab Bacterial Typing System for Escherichia coli and Klebsiella spp.

    JOURNAL OF CLINICAL MICROBIOLOGY . 51(12): 3944-3949. Number of citations: 10

    [doi:10.1128/JCM.01664-13]

  • Novais C, Freitas AR, Silveira E, Antunes P, Silva R, Coque TM, Peixe L.

    Spread of multidrug-resistant Enterococcus to animals and humans: an underestimated role for the pig farm environment

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 68(12): 2746-2754. Number of citations: 55

    [doi:10.1093/jac/dkt289]

  • Holguín Á, Yebra G, Martín L, de Pineda AT, Ruiz LE, Quezada AY, Nieto AI, Escobar G.

    Transmitted drug-resistance in human immunodeficiency virus-infected adult population in El Salvador, Central America.

    CLINICAL MICROBIOLOGY AND INFECTION . 19(12): 523-532. Number of citations: 10

    [doi:10.1111/1469-0691.12264]

  • Hernández-Jiménez E, Del Campo R, Toledano V, Vallejo-Cremades MT, Muñoz A, Largo C, Arnalich F, García-Rio F, Cubillos-Zapata C, López-Collazo E.

    Biofilm vs. planktonic bacterial mode of growth: Which do human macrophages prefer?

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS . 441(4): 947-952. Number of citations: 30

    [doi:10.1016/j.bbrc.2013.11.012]

  • Villa L, Capone A, Fortini D, Dolejska M, Rodríguez I, Taglietti F, De Paolis P, Petrosillo N, Carattoli A.

    Reversion to susceptibility of a carbapenem-resistant clinical isolate of Klebsiella pneumoniae producing KPC-3

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 68(11): 2482-2486. Number of citations: 37

    [doi:10.1093/jac/dkt235]

  • Delgado-Rodríguez M, Castilla J, Godoy P, Martín V, Soldevila N, Alonso J, Astray J, Baricot M, Galán JC, Castro A, Gónzález-Candelas F, Mayoral JM, Quintana JM, Pumarola T, Tamames S, Sáez M, Domínguez A, CIBERESP Cases and Controls in Pandemic Influenza Working Group, Spain.

    Different prognosis in hospitalized patients with influenza one season after the pandemic H1N1 influenza of 2009-2010 in Spain.

    INFLUENZA AND OTHER RESPIRATORY VIRUSES . 7(6): 1336-1342. Number of citations: 5

    [doi:10.1111/irv.12119]

  • Díez-Aguilar M, Morosini MI, del Campo R, García-Castillo M, Zamora J, Cantón R.

    In Vitro Activity of Fosfomycin against a Collection of Clinical Pseudomonas aeruginosa Isolates from 16 Spanish Hospitals: Establishing the Validity of Standard Broth Microdilution as Susceptibility Testing Method

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 57(11): 5701-5703. Number of citations: 28

    [doi:10.1128/AAC.00589-13]

  • Tenover FC, Canton R, Kop J, Chan R, Ryan J, Weir F, Ruiz-Garbajosa P, LaBombardi V, Persing DH.

    Detection of Colonization by Carbapenemase-Producing Gram-Negative Bacilli in Patients by Use of the Xpert MDRO Assay

    JOURNAL OF CLINICAL MICROBIOLOGY . 51(11): 3780-3787. Number of citations: 63

    [doi:10.1128/JCM.01092-13]

  • Ruiz-Garbajosa P, Curiao T, Tato M, Gijón D, Pintado V, Valverde A, Baquero F, Morosini MI, Coque TM, Cantón R.

    Multiclonal dispersal of KPC genes following the emergence of non-ST258 KPC-producing Klebsiella pneumoniae clones in Madrid, Spain.

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 68(11): 2487-2492. Number of citations: 42

    [doi:10.1093/jac/dkt237]

  • Reales-Calderón JA, Sylvester M, Strijbis K, Jensen ON, Nombela C, Molero G, Gil C.

    Candida albicans induces pro-inflammatory and anti-apoptotic signals in macrophages as revealed by quantitative proteomics and phosphoproteomics

    JOURNAL OF PROTEOMICS . 91: 106-135. Number of citations: 31

    [doi:10.1016/j.jprot.2013.06.026]

  • Morosini MI, Quereda C, Gil H, Anda P, Núñez-Murga M, Cantón R, López-Vélez R.

    Melioidosis in Traveler from Africa to Spain

    EMERGING INFECTIOUS DISEASES . 19(10): 1656-1659. Number of citations: 21

    [doi:10.3201/eid1910.121785]

  • Wu G, Day MJ, Mafura MT, Nunez-Garcia J, Fenner JJ, Sharma M, van Essen-Zandbergen A, Rodríguez I, Dierikx C, Kadlec K, Schink AK, Chattaway M, Wain J, Helmuth R, Guerra B, Schwarz S, Threlfall J, Woodward MJ, Woodford N, Coldham N, Mevius D.

    Comparative Analysis of ESBL-Positive Escherichia coli Isolates from Animals and Humans from the UK, The Netherlands and Germany

    Plos One . 8(9): . Number of citations: 107

    [doi:10.1371/journal.pone.0075392]

  • Turrientes MC, Baquero F, Levin BR, Martínez JL, Ripoll A, González-Alba JM, Tobes R, Manrique M, Baquero MR, Rodríguez-Domínguez MJ, Cantón R, Galán JC.

    Normal mutation rate variants arise in a Mutator (Mut S) Escherichia coli population.

    Plos One . 8(9): . Number of citations: 29

    [doi:10.1371/journal.pone.0072963]