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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

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Only original articles, editorials, guidelines.

  • Cueva C, Bartolomé B, Moreno-Arribas MV, Bustos I, Requena T, González-Manzano S, Santos-Buelga C, Turrientes MC, del Campo R.

    Susceptibility and Tolerance of Human Gut Culturable Aerobic Microbiota to Wine Polyphenols

    MICROBIAL DRUG RESISTANCE . 21(1): 17-24. Number of citations: 3

    [doi:10.1089/mdr.2014.0074]

  • Cano Megías M, González Albarrán O, Guisado Vasco P, Lamas Ferreiro A, Máiz Carro L.

    Insulin resistance, beta-cell dysfunction and differences in curves of plasma glucose and insulin in the intermediate points of the standard glucose tolerance test in adults with cystic fibrosis

    ENDOCRINOLOGIA Y NUTRICION . 62(2): 91-99. Number of citations: 14

    [doi:10.1016/j.endonu.2014.08.002]

  • Fernández McPhee C, Álvarez P, Prieto L, Obiang J, Avedillo P, Vargas A, Rojo P, Abad C, Ramos JT, Holguín A.

    HIV-1 infection using dried blood spots can be confirmed by Bio-Rad Geenius™ HIV 1/2 confirmatory assay.

    JOURNAL OF CLINICAL VIROLOGY . 63: 66-69. Number of citations: 9

    [doi:10.1016/j.jcv.2014.12.018]

  • Báez J, Hernández-García M, Guamparito C, Díaz S, Olave A, Guerrero K, Cantón R, Baquero F, Gahona J, Valenzuela N, Del Campo R, Silva J.

    Molecular characterization and genetic diversity of ESBL-producing Escherichia coli colonizing the migratory Franklin's gulls (Leucophaeus pipixcan) in Antofagasta, North of Chile.

    MICROBIAL DRUG RESISTANCE . 21(1): 111-116. Number of citations: 34

    [doi:10.1089/mdr.2014.0158]

  • Martínez JL, Coque TM, Baquero F.

    What is a resistance gene? Ranking risk in resistomes.

    NATURE REVIEWS MICROBIOLOGY . 13(2): 116-123. Number of citations: 443

    [doi:10.1038/nrmicro3399]

  • Brown D, Canton R, Dubreuil L, Gatermann S, Giske C, MacGowan A, Martinez-Martinez L, Mouton J, Skov R, Steinbakk M, Walton C, Heuer O, Struelens MJ, Diaz Hogberg L, Kahlmeter G.

    Widespread implementation of EUCAST breakpoints for antibacterial susceptibility testing in Europe

    Eurosurveillance . 20(2): 21-28. Number of citations: 23

    [doi:10.2807/1560-7917.ES2015.20.2.21008]

  • Tiddens HA, De Boeck K, Clancy JP, Fayon M, H G M A, Bresnik M, Derchak A, Lewis SA, Oermann CM, ALPINE study investigators.

    Open label study of inhaled aztreonam for Pseudomonas eradication in children with cystic fibrosis: The ALPINE study

    JOURNAL OF CYSTIC FIBROSIS . 14(1): 111-119. Number of citations: 40

    [doi:10.1016/j.jcf.2014.06.003]

  • Megías MC, Albarrán OG, Vasco PG, Ferreiro AL, Carro LM.

    Influence of macrolides, nutritional support and respiratory therapies in diabetes and normal glucose tolerance in cystic fibrosis. A retrospective analysis of a cohort of adult and younger patients

    DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS . 9(1): 1-6. Number of citations: 3

    [doi:10.1016/j.dsx.2014.09.016]

  • Máiz L, Vendrell M, Olveira C, Girón R, Nieto R, Martínez-García MÁ.

    Prevalence and Factors Associated with Isolation of Aspergillus and Candida from Sputum in Patients with Non-Cystic Fibrosis Bronchiectasis

    Respiration . 89(5): 396-403. Number of citations: 36

    [doi:10.1159/000381289]

  • Lopez, Y., Tato, M., Espinal, P., Garcia-Alonso, F., Gargallo-Viola, D., Canton, R., Vila, J..

    In vitro selection of mutants resistant to ozenoxacin compared with levofloxacin and ciprofloxacin in Gram-positive cocci

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 70(1): 57-61. Number of citations: 11

    [doi:10.1093/jac/dku375]

  • Oggioni MR, Coelho JR, Furi L, Knight DR, Viti C, Orefici G, Martinez JL, Freitas AT, Coque TM, Morrissey I, BIOHYPO consortium.

    Significant Differences Characterise the Correlation Coefficients between Biocide and Antibiotic Susceptibility Profiles in Staphylococcus aureus

    CURRENT PHARMACEUTICAL DESIGN . 21(16): 2054-2057. Number of citations: 22

    [doi:10.2174/1381612821666150310103238]

  • Prieto LM, González-Tomé MI, Muñoz E, Fernández-Ibieta M, Soto B, Álvarez A, Navarro ML, Roa MÁ, Beceiro J, de José MI, Olabarrieta I, Lora D, Ramos JT, Madrid Cohort of HIV-Infected Mother-Infant Pairs.

    Birth defects in a cohort of infants born to HIV-infected women in Spain, 2000-2009.

    BMC INFECTIOUS DISEASES . 14: 700-700. Number of citations: 6

    [doi:10.1186/s12879-014-0700-3]

  • Caballero Jde D, Del Campo R, Tato M, Gómez G de la Pedrosa E, Cobo M, López-Causapé C, Gómez-Mampaso E, Oliver A, Cantón R.

    Microbiological diagnostic procedures for respiratory cystic fibrosis samples in Spain: towards standard of care practices

    BMC MICROBIOLOGY . 14(1): 335-335. Number of citations: 7

    [doi:10.1186/s12866-014-0335-y]

  • de Been M, Lanza VF, de Toro M, Scharringa J, Dohmen W, Du Y, Hu J, Lei Y, Li N, Tooming-Klunderud A, Heederik DJ, Fluit AC, Bonten MJ, Willems RJ, de la Cruz F, van Schaik W.

    Dissemination of Cephalosporin Resistance Genes between Escherichia coli Strains from Farm Animals and Humans by Specific Plasmid Lineages

    PLOS GENETICS . 10(12): . Number of citations: 208

    [doi:10.1371/journal.pgen.1004776]

  • Cantón R, Canut A, Morosini MI, Oliver A.

    Breakpoints for carbapenemase-producing Enterobacteriaceae: is the problem solved?

    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA . 32 Suppl 4: 33-40.

    [doi:10.1016/S0213-005X(14)70172-7]

  • Lanza VF, de Toro M, Garcillán-Barcia MP, Mora A, Blanco J, Coque TM, de la Cruz F.

    Plasmid Flux in Escherichia coli ST131 Sublineages, Analyzed by Plasmid Constellation Network (PLACNET), a New Method for Plasmid Reconstruction from Whole Genome Sequences

    PLOS GENETICS . 10(12): . Number of citations: 106

    [doi:10.1371/journal.pgen.1004766]

  • García-Descalzo L, García-López E, Alcázar A, Baquero F, Cid C.

    Proteomic analysis of the adaptation to warming in the Antarctic bacteria Shewanella frigidimarina.

    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS . 1844(12): 2229-2240. Number of citations: 14

    [doi:10.1016/j.bbapap.2014.08.006]

  • Vergara A, Zboromyrska Y, Mosqueda N, Morosini MI, García-Fernández S, Roca I, Cantón R, Marco F, Vila J.

    Evaluation of a Loop-Mediated Isothermal Amplification-Based Methodology To Detect Carbapenemase Carriage in Acinetobacter Clinical Isolates

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 58(12): 7538-7540. Number of citations: 19

    [doi:10.1128/AAC.03870-14]