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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Rojo-Molinero E, Macià MD, Rubio R, Moyà B, Cabot G, López-Causapé C, Pérez JL, Cantón R, Oliver A.

    Sequential Treatment of Biofilms with Aztreonam and Tobramycin Is a Novel Strategy for Combating Pseudomonas aeruginosa Chronic Respiratory Infections.

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 60(5): 2912-2922. Number of citations: 13

    [doi:10.1128/AAC.00196-16]

  • Úbeda M, Lario M, Muñoz L, Borrero MJ, Rodríguez-Serrano M, Sánchez-Díaz AM, Del Campo R, Lledó L, Pastor Ó, García-Bermejo L, Díaz D, Álvarez-Mon M, Albillos A.

    Obeticholic acid reduces bacterial translocation and inhibits intestinal inflammation in cirrhotic rats.

    JOURNAL OF HEPATOLOGY . 64(5): 1049-1057. Number of citations: 85

    [doi:10.1016/j.jhep.2015.12.010]

  • de Dios Caballero J, Del Campo R, Royuela A, Solé A, Máiz L, Olveira C, Quintana-Gallego E, de Gracia J, Cobo M, de la Pedrosa EG, Oliver A, Cantón R, GEIFQ (Grupo Español para el Estudio de la Colonización/Infección Broncopulmonar.

    Bronchopulmonary infection-colonization patterns in Spanish cystic fibrosis patients: Results from a national multicenter study

    JOURNAL OF CYSTIC FIBROSIS . 15(3): 357-365. Number of citations: 12

    [doi:10.1016/j.jcf.2015.09.004]

  • Carrasco G, de Dios Caballero J, Garrido N, Valdezate S, Cantón R, Sáez-Nieto JA.

    Shortcomings of the Commercial MALDI-TOF MS Database and Use of MLSA as an Arbiter in the Identification of Nocardia Species.

    FRONTIERS IN MICROBIOLOGY . 7: 542-542.

    [doi:10.3389/fmicb.2016.00542]

  • Chueca N, Rivadulla I, Lovatti R, Reina G, Blanco A, Fernandez-Caballero JA, Cardeñoso L, Rodriguez-Granjer J, Fernandez-Alonso M, Aguilera A, Alvarez M, Galán JC, García F.

    Using NS5B Sequencing for Hepatitis C Virus Genotyping Reveals Discordances with Commercial Platforms.

    Plos One . 11(4): . Number of citations: 28

    [doi:10.1371/journal.pone.0153754]

  • Morales-Suárez-Varela M, Llopis-González A, González-Candela F, Astray J, Alonso J, Garin O, Castro A, Galan JC, Soldevila N, Castilla J, Godoy P, Delgado-Rodríguez M, Martin V, Mayoral JM, Pumarola T, Quintana JM, Tamames S, Rubio-López N, Dominguez A.

    Economic Evaluation of Health Services Costs During Pandemic Influenza A (H1N1) Pdm09 Infection in Pregnant and Non-Pregnant Women in Spain.

    IRANIAN JOURNAL OF PUBLIC HEALTH . 45(4): 423-434. Number of citations: 2

  • Escobar-Villalba A, Sainz de la Maza S, Pérez Torre P, Galán JC, Rodríguez-Domínguez M, Monreal Laguillo E, Martínez Ulloa PL, Buisán Catevilla J, Corral I.

    Acute myelitis by human herpes virus 7 in an HIV-infected patient.

    JOURNAL OF CLINICAL VIROLOGY . 77: 63-65. Number of citations: 8

    [doi:10.1016/j.jcv.2016.02.001]

  • María DA, María-Isabel M, María-Carmen C, Álvaro P, Jorge C, Luis MM, Francesc M, Jordi V, Adriana O, Jesús O, Rafael C.

    Establishing the validity of different susceptibility testing methods to evaluate the in vitro activity of amoxicillin-clavulanate against Escherichia coli.

    DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE . 84(4): 334-336. Number of citations: 3

    [doi:10.1016/j.diagmicrobio.2015.12.012]

  • Butt J, Romero-Hernández B, Pérez-Gómez B, Willhauck-Fleckenstein M, Holzinger D, Martin V, Moreno V, Linares C, Dierssen-Sotos T, Barricarte A, Tardón A, Altzibar JM, Moreno-Osset E, Franco F, Olmedo Requena R, María Huerta J, Michel A, Waterboer T, Castaño-Vinyals G, Kogevinas M, Pollán M, Boleij A, de Sanjosé S, Del Campo R, Tjalsma H, Aragonés N, Pawlita M.

    Association of Streptococcus gallolyticus subspecies gallolyticus with colorectal cancer: Serological evidence

    INTERNATIONAL JOURNAL OF CANCER . 138(7): 1670-1679. Number of citations: 30

    [doi:10.1002/ijc.29914]

  • Pujol J, Godoy P, Soldevila N, Castilla J, González-Candelas F, Mayoral JM, Astray J, Garcia S, Martin V, Tamames S, Delgado M, Domínguez A.

    Social class based on occupation is associated with hospitalization for A(H1N1)pdm09 infection. Comparison between hospitalized and ambulatory cases.

    EPIDEMIOLOGY AND INFECTION . 144(4): 732-740. Number of citations: 5

    [doi:10.1017/S0950268815001892]

  • Ponce-Alonso M, Rodríguez-Rojas L, Campo RD, Cantón R, Morosini MI.

    Comparison of different methods for identification of species of the genus Raoultella: report of 11 cases of Raoultella causing bacteraemia and literature review

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases . 22(3): 252-257. Number of citations: 28

    [doi:10.1016/j.cmi.2015.10.035]

  • Clutter DS, Sánchez PR, Rhee SY, Shafer RW.

    Genetic Variability of HIV-1 for Drug Resistance Assay Development.

    VIRUSES-BASEL . 8(2): . Number of citations: 12

    [doi:10.3390/v8020048]

  • Gil-Bona A, Reales-Calderon JA, Parra-Giraldo CM, Martinez-Lopez R, Monteoliva L, Gil C.

    The Cell Wall Protein Ecm33 of Candida albicans is Involved in Chronological Life Span, Morphogenesis, Cell Wall Regeneration, Stress Tolerance, and Host-Cell Interaction.

    FRONTIERS IN MICROBIOLOGY . 7: 64-64. Number of citations: 24

    [doi:10.3389/fmicb.2016.00064]

  • Díez-Aguilar M, Martínez-García L, Cantón R, Morosini MI.

    Is a New Standard Needed for Diffusion Methods for In Vitro Susceptibility Testing of Fosfomycin against Pseudomonas aeruginosa?

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 60(2): 1158-1161. Number of citations: 7

    [doi:10.1128/AAC.02237-15]

  • García-Fernández S, Morosini MI, Gijón D, Beatobe L, Ruiz-Garbajosa P, Domínguez L, Cantón R, Valverde A.

    Detection of Carbapenemase Production in a Collection of Enterobacteriaceae with Characterized Resistance Mechanisms from Clinical and Environmental Origins by Use of Both Carba NP and Blue-Carba Tests

    JOURNAL OF CLINICAL MICROBIOLOGY . 54(2): 464-466. Number of citations: 16

    [doi:10.1128/JCM.02580-15]

  • Llácer Delicado T, Torrecilla E, Holguín Á.

    Deep analysis of HIV-1 natural variability across HIV-1 variants at residues associated with integrase inhibitor (INI) resistance in INI-naive individuals.

    The Journal of antimicrobial chemotherapy . 71(2): 362-366. Number of citations: 13

    [doi:10.1093/jac/dkv333]

  • Delgado-Valverde M, Torres E, Valiente-Mendez A, Almirante B, Gómez-Zorrilla S, Borrell N, Corzo JE, Gurgui M, Almela M, García-Álvarez L, Fontecoba-Sánchez MC, Martínez-Martínez L, Cantón R, Praena J, Causse M, Gutiérrez-Gutiérrez B, Roberts JA, Farkas A, Pascual Á, Rodríguez-Baño J, REIPI/GEIH-SEIMC BACTERAEMIA-MIC group.

    Impact of the MIC of piperacillin/tazobactam on the outcome for patients with bacteraemia due to Enterobacteriaceae: the Bacteraemia-MIC project

    The Journal of antimicrobial chemotherapy . 71(2): 521-530. Number of citations: 17

    [doi:10.1093/jac/dkv362]

  • Palacios-Baena ZR, Oteo J, Conejo C, Larrosa MN, Bou G, Fernández-Martínez M, González-López JJ, Pintado V, Martínez-Martínez L, Merino M, Pomar V, Mora-Rillo M, Rivera MA, Oliver A, Ruiz-Carrascoso G, Ruiz-Garbajosa P, Zamorano L, Bautista V, Ortega A, Morales I, Pascual Á, Campos J, Rodríguez-Baño J.

    Comprehensive clinical and epidemiological assessment of colonisation and infection due to carbapenemase-producing Enterobacteriaceae in Spain

    JOURNAL OF INFECTION . 72(2): 152-160. Number of citations: 53

    [doi:10.1016/j.jinf.2015.10.008]