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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • López-Sanromán A, Rodríguez de Santiago E, Cobo Reinoso J, Del Campo Moreno R, Foruny Olcina JR, García Fernández S, García García de Paredes A, Aguilera Castro L, Ferre Aracil C, Albillos Martínez A.

    Results of the implementation of a multidisciplinary programme of faecal microbiota transplantation by colonoscopy for the treatment of recurrent Clostridium difficile infection.

    GASTROENTEROLOGIA Y HEPATOLOGIA . 40(9): 605-614. Number of citations: 2

    [doi:10.1016/j.gastrohep.2017.03.004]

  • Rojas Sánchez P, Cobos A, Navaro M, Ramos JT, Pagán I, Holguín Á.

    Impact of Clinical Parameters in the Intrahost Evolution of HIV-1 Subtype B in Pediatric Patients: A Machine Learning Approach.

    GENOME BIOL EVOL . 9(10): 2715-2726. Number of citations: 3

    [doi:10.1093/gbe/evx193]

  • Fernández de Larrea-Baz N, Pérez-Gómez B, Michel A, Romero B, Lope V, Pawlita M, Fernández-Villa T, Moreno V, Martín V, Willhauck-Fleckenstein M, López-Abente G, Castilla J, Fernández-Tardón G, Dierssen-Sotos T, Santibáñez M, Peiró R, Jiménez-Moleón JJ, Navarro C, Castaño-Vinyals G, Kogevinas M, Pollán M, de Sanjosé S, Del Campo R, Waterboer T, Aragonés N.

    Helicobacter pylori serological biomarkers of gastric cancer risk in the MCC-Spain case-control Study.

    CANCER EPIDEMIOLOGY . 50(Pt A): 76-84. Number of citations: 10

    [doi:10.1016/j.canep.2017.08.002]

  • Rodríguez-Domínguez M, González-Alba JM, Puerta T, Martínez-García L, Menéndez B, Cantón R, Romero JD, Galán JC.

    Spread of a new Chlamydia trachomatis variant from men who have sex with men to the heterosexual population after replacement and recombination in ompA and pmpH genes.

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases . 23(10): 761-766. Number of citations: 1

    [doi:10.1016/j.cmi.2017.03.009]

  • de Dios Caballero J, Vida R, Cobo M, Máiz L, Suárez L, Galeano J, Baquero F, Cantón R, Del Campo R.

    Individual Patterns of Complexity in Cystic Fibrosis Lung Microbiota, Including Predator Bacteria, over a 1-Year Period.

    Mbio . 8(5): . Number of citations: 26

    [doi:10.1128/mBio.00959-17]

  • Ruiz-Garbajosa P, Cantón R.

    Epidemiology of antibiotic resistance in Pseudomonas aeruginosa. Implications for empiric and definitive therapy.

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 30 Suppl 1: 8-12. Number of citations: 26

  • Polverino E, Goeminne PC, McDonnell MJ, Aliberti S, Marshall SE, Loebinger MR, Murris M, Cantón R, Torres A, Dimakou K, De Soyza A, Hill AT, Haworth CS, Vendrell M, Ringshausen FC, Subotic D, Wilson R, Vilaró J, Stallberg B, Welte T, Rohde G, Blasi F, Elborn S, Almagro M, Timothy A, Ruddy T, Tonia T, Rigau D, Chalmers JD.

    European Respiratory Society guidelines for the management of adult bronchiectasis.

    The European respiratory journal . 50(3): . Number of citations: 499

    [doi:10.1183/13993003.00629-2017]

  • San Millan A, MacLean RC.

    Fitness Costs of Plasmids: a Limit to Plasmid Transmission.

    Microbiology spectrum . 5(5): . Number of citations: 153

    [doi:10.1128/microbiolspec.MTBP-0016-2017]

  • Arboledas JCA, Guerrero IP, Rodríguez MJB, Martos ET, Pérez AB, León CC, Sierra Sánchez JF, Prieto MDL, Porcuna NC, Mochón MDO, Macías J, de la Iglesia Salgado A, Granger JR, Fernández MD, Lozano IG, Ramírez ER, Rivero A, Del Carmen Lozano Domínguez M, Viciana I, Montemayor JCG, García FG.

    Hepatitis C virus core antigen in the management of patients treated with new direct-acting antivirals.

    DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE . 89(1): 29-34. Number of citations: 9

    [doi:10.1016/j.diagmicrobio.2017.06.006]

  • López-Causapé C, de Dios-Caballero J, Cobo M, Escribano A, Asensio Ó, Oliver A, Del Campo R, Cantón R, MAIZ CARRO, LUIS MARIA.

    Antibiotic resistance and population structure of cystic fibrosis Pseudomonas aeruginosa isolates from a Spanish multi-centre study.

    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS . 50(3): 334-341. Number of citations: 11

    [doi:10.1016/j.ijantimicag.2017.03.034]

  • Aguilera A, Navarro D, Rodríguez Frias F, Viciana I, Martínez-Sapiña AM, Rodríguez MJ, Martró E, Del Carmen Lozano M, Coletta E, Cardeñoso L, Suárez A, Trigo M, Rodríguez-Granjer J, Montiel N, de la Iglesia A, Alados JC, Vegas C, Bernal S, Fernández-Cuenca F, Pena MJ, Reina G, García-Bujalance S, Echevarria MJ, Benítez L, Pérez-Castro S, Ocete D, García-Arata I, Guerrero C, Rodríguez-Iglesias M, Casas P, García F.

    Prevalence and distribution of hepatitis C virus genotypes in Spain during the 2000-2015 period (the GEHEP 005 study).

    JOURNAL OF VIRAL HEPATITIS . 24(9): 725-732. Number of citations: 21

    [doi:10.1111/jvh.12700]

  • Prieto LM, Fernández McPhee C, Rojas P, Mazariegos D, Muñoz E, Mellado MJ, Holguín Á, Navarro ML, González-Tomé MI, Ramos JT, Madrid Cohort of HIV-Infected Mother-Infant Pairs.

    Pregnancy outcomes in perinatally HIV-infected young women in Madrid, Spain: 2000-2015.

    Plos One . 12(8): . Number of citations: 9

    [doi:10.1371/journal.pone.0183558]

  • Raoult D, Baquero F.

    Rewiring Microbiology and Infection.

    CLINICAL INFECTIOUS DISEASES . 65(suppl_1): . Number of citations: 3

    [doi:10.1093/cid/cix345]

  • Baquero F.

    Basic Sciences Fertilizing Clinical Microbiology and Infection Management.

    CLINICAL INFECTIOUS DISEASES . 65(suppl_1): . Number of citations: 2

    [doi:10.1093/cid/cix350]

  • López-Causapé C, Sommer LM, Cabot G, Rubio R, Ocampo-Sosa AA, Johansen HK, Figuerola J, Cantón R, Kidd TJ, Molin S, Oliver A.

    Evolution of the Pseudomonas aeruginosa mutational resistome in an international Cystic Fibrosis clone.

    SCIENTIFIC REPORTS . 7(1): 5555-5555. Number of citations: 82

    [doi:10.1038/s41598-017-05621-5]

  • Moore NM, Cantón R, Carretto E, Peterson LR, Sautter RL, Traczewski MM, Carba-R Study Team.

    Rapid Identification of Five Classes of Carbapenem Resistance Genes Directly from Rectal Swabs by Use of the Xpert Carba-R Assay.

    JOURNAL OF CLINICAL MICROBIOLOGY . 55(7): 2268-2275. Number of citations: 33

    [doi:10.1128/JCM.00137-17]

  • Chacón L, Mateos ML, Holguín Á.

    Relevance of cutoff on a 4th generation ELISA performance in the false positive rate during HIV diagnostic in a low HIV prevalence setting.

    JOURNAL OF CLINICAL VIROLOGY . 92: 11-13. Number of citations: 25

    [doi:10.1016/j.jcv.2017.04.014]

  • Gutiérrez-Gutiérrez B, Salamanca E, de Cueto M, Hsueh PR, Viale P, Paño-Pardo JR, Venditti M, Tumbarello M, Daikos G, Cantón R, Doi Y, Tuon FF, Karaiskos I, Pérez-Nadales E, Schwaber MJ, Azap ÖK, Souli M, Roilides E, Pournaras S, Akova M, Pérez F, Bermejo J, Oliver A, Almela M, Lowman W, Almirante B, Bonomo RA, Carmeli Y, Paterson DL, Pascual A, Rodríguez-Baño J, REIPI/ESGBIS/INCREMENT Investigators.

    Effect of appropriate combination therapy on mortality of patients with bloodstream infections due to carbapenemase-producing Enterobacteriaceae (INCREMENT): a retrospective cohort study.

    LANCET INFECTIOUS DISEASES . 17(7): 726-734. Number of citations: 275

    [doi:10.1016/S1473-3099(17)30228-1]