Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Tedim AP, Lanza VF, Manrique M, Pareja E, Ruiz-Garbajosa P, Cantón R, Baquero F, Coque TM, Tobes R.

    Complete Genome Sequences of Isolates of Enterococcus faecium Sequence Type 117, a Globally Disseminated Multidrug-Resistant Clone.

    Genome announcements . 5(13): .

    [doi:10.1128/genomeA.01553-16]

  • Rojas Sánchez P, Prieto L, Jiménez De Ory S, Fernández Cooke E, Navarro ML, Ramos JT, Holguín Á, Madrid Cohort of HIV-1 Infected Children and Adolescents Integrated in the Paedi.

    Impact of lopinavir-ritonavir exposure in HIV-1 infected children and adolescents in Madrid, Spain during 2000-2014.

    Plos One . 12(3): . Number of citations: 6

    [doi:10.1371/journal.pone.0173168]

  • Calvo-Lerma J, Martinez-Jimenez CP, Lázaro-Ramos JP, Andrés A, Crespo-Escobar P, Stav E, Schauber C, Pannese L, Hulst JM, Suárez L, Colombo C, Barreto C, de Boeck K, Ribes-Koninckx C, MyCyFAPP.

    Innovative approach for self-management and social welfare of children with cystic fibrosis in Europe: development, validation and implementation of an mHealth tool (MyCyFAPP).

    BMJ open . 7(3): . Number of citations: 22

    [doi:10.1136/bmjopen-2016-014931]

  • Carrillo-Salinas FJ, Mestre L, Mecha M, Feliú A, Del Campo R, Villarrubia N, Espejo C, Montalbán X, Álvarez-Cermeño JC, Villar LM, Guaza C.

    Gut dysbiosis and neuroimmune responses to brain infection with Theiler's murine encephalomyelitis virus.

    SCIENTIFIC REPORTS . 7: 44377-44377. Number of citations: 29

    [doi:10.1038/srep44377]

  • SANCHEZ VALENZUELA, ANTONIO JESUS, RIPOLL GONZALEZ, AIDA, TURRIENTES LÓPEZ, MARÍA CARMEN, MORALES BARTOLOMÉ, EVA, RODRIGUEZ BAÑOS, MERCEDES, Mariona Bustamante, LOPEZ ESPINOSA, MARÍA JOSÉ, Sabrina Llopd, Loreto Santa-Marina, Ana Jiménez-Zabalae, MORENO BOFARULL, ANA, CANTÓN MORENO, RAFAEL, Jordi Sunyerc,, COQUE GONZÁLEZ, MARÍA TERESA, BAQUERO MOCHALES, FERNANDO.

    Copper Resistance in Aerobic Intestinal Bacteria from Children with Different Levels of Copper-Exposure

    Journal of Environment and Health Science . 3(1): 1-13.

    [doi:10.15436/2378-6841.17.1219]

  • Carvalho I, Del Campo R, Sousa M, Silva N, Carrola J, Marinho C, Santos T, Carvalho S, Nóvoa M, Quaresma M, Pereira JE, Cobo M, Igrejas G, Poeta P.

    Antimicrobial-resistant Escherichia coli and Enterococcus spp. isolated from Miranda donkey (Equus asinus): an old problem from a new source with a different approach.

    JOURNAL OF MEDICAL MICROBIOLOGY . 66(2): 191-202.

    [doi:10.1099/jmm.0.000423]

  • García-Fernández S, Hernández-García M, Valverde A, Ruiz-Garbajosa P, Morosini MI, Cantón R.

    CHROMagar mSuperCARBA performance in carbapenem-resistant Enterobacteriaceae isolates characterized at molecular level and routine surveillance rectal swab specimens.

    DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE . 87(3): 207-209. Number of citations: 10

    [doi:10.1016/j.diagmicrobio.2016.11.014]

  • Levin BR, McCall IC, Perrot V, Weiss H, Ovesepian A, Baquero F.

    A Numbers Game: Ribosome Densities, Bacterial Growth, and Antibiotic-Mediated Stasis and Death.

    Mbio . 8(1): . Number of citations: 30

    [doi:10.1128/mBio.02253-16]

  • Grundmann H, Glasner C, Albiger B, Aanensen DM, Tomlinson CT, Andrasevic AT, Cantón R, Carmeli Y, Friedrich AW, Giske CG, Glupczynski Y, Gniadkowski M, Livermore DM, Nordmann P, Poirel L, Rossolini GM, Seifert H, Vatopoulos A, Walsh T, Woodford N, Monnet DL, European Survey of Carbapenemase-Producing Enterobacteriaceae (EuSCAPE) Working.

    Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study.

    The Lancet. Infectious diseases . 17(2): 153-163.

    [doi:10.1016/S1473-3099(16)30257-2]

  • Bordallo-Cardona MÁ, Escribano P, Gómez G de la Pedrosa E, Marcos-Zambrano LJ, Cantón R, Bouza E, Guinea J.

    In Vitro Exposure to Increasing Micafungin Concentrations Easily Promotes Echinocandin Resistance in Candida glabrata Isolates.

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 61(2): . Number of citations: 26

    [doi:10.1128/AAC.01542-16]

  • Cantón R, Livermore DM, Morosini MI, Díaz-Regañón J, Rossolini GM, PREMIUM Study Group.

    Etest® versus broth microdilution for ceftaroline MIC determination with Staphylococcus aureus: results from PREMIUM, a European multicentre study.

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 72(2): 431-436. Number of citations: 14

    [doi:10.1093/jac/dkw442]

  • Rodrigues C, Novais Â, Sousa C, Ramos H, Coque TM, Cantón R, Lopes JA, Peixe L.

    Elucidating constraints for differentiation of major human Klebsiella pneumoniae clones using MALDI-TOF MS.

    EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES . 36(2): 379-386. Number of citations: 12

    [doi:10.1007/s10096-016-2812-8]

  • Ponce-Alonso M, Del Campo R, Fortun J, Canton R, Morosini MI.

    First description of late recurrence of catheter-associated bacteraemia due to Cellulosimicrobium cellulans.

    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA . 35(2): 131-133. Number of citations: 3

    [doi:10.1016/j.eimc.2016.05.003]

  • Lanza VF, Baquero F, de la Cruz F, Coque TM.

    AcCNET (Accessory Genome Constellation Network): comparative genomics software for accessory genome analysis using bipartite networks.

    Bioinformatics . 33(2): 283-285. Number of citations: 31

    [doi:10.1093/bioinformatics/btw601]

  • Cantón R, Díez-Aguilar M, Morosini MI.

    Puntos de corte de dalbavancina y recomendaciones para el estudio de su actividad in vitro.

    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA . 35 Suppl 1: 15-21.

    [doi:10.1016/S0213-005X(17)30030-7]

  • Ellington MJ, Ekelund O, Aarestrup FM, Canton R, Doumith M, Giske C, Grundman H, Hasman H, Holden M, Hopkins KL, Iredell J, Kahlmeter G, Köser CU, MacGowan A, Mevius D, Mulvey M, Naas T, Peto T, Rolain JM, Samuelsen Ø, Woodford N.

    The role of whole genome sequencing in antimicrobial susceptibility testing of bacteria: report from the EUCAST Subcommittee.

    CLINICAL MICROBIOLOGY AND INFECTION . 23(1): 2-22. Number of citations: 245

    [doi:10.1016/j.cmi.2016.11.012]

  • Martínez JL, Coque TM, Lanza VF, de la Cruz F, Baquero F.

    Genomic and metagenomic technologies to explore the antibiotic resistance mobilome.

    Annals of the New York Academy of Sciences . 1388(1): 26-41. Number of citations: 24

    [doi:10.1111/nyas.13282]

  • Alvarez P, Prieto L, Martín L, Obiang J, Avedillo P, Vargas A, Rojo P, Fernández McPhee C, Sanz Canalejas L, Benito A, Tomás Ramos J, Holguín Á.

    Evaluation of four commercial virological assays for early infant HIV-1 diagnosis using dried blood specimens.

    PEDIATRIC RESEARCH . 81(1-1): 80-87. Number of citations: 11

    [doi:10.1038/pr.2016.183]