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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

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Only original articles, editorials, guidelines.

  • Costa-Alcalde JJ, Barbeito-Castiñeiras G, González-Alba JM, Aguilera A, Galán JC, Pérez-Del-Molino ML.

    Comparative evaluation of the identification of rapidly growing non-tuberculous mycobacteria by mass spectrometry (MALDI-TOF MS), GenoType Mycobacterium CM/AS assay and partial sequencing of the rpoß gene with phylogenetic analysis as a reference method.

    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA . 37(3): 160-166. Number of citations: 4

    [doi:10.1016/j.eimc.2018.04.012]

  • Filipovic, Sanja Kurecic, Visekruna-Vucina, Vesna, Novosel, Iva Pem, Lovric, Zvjezdana, Petrovic, Goranka, Drazenovic, Vladimir, Vince, Adriana, Topic, Antea, Mihalic, Jelena Budimir, Huljev, Eva, Luksic, Boris, Karabuva, Svjetlana, Cikes, Mihaela, Emborg, Hanne-Dorthe, Trebbien, Ramona, Helmuth, Ida Glode, Krause, Tyra Grove, Lina, Bruno, Falchi, Alessandra, Vilcu, Ana-Maria, Souty, Cecile, Blanchon, Thierry, Launay, Titouan, van der Werf, Sylvie, Enouf, Vincent, Behillil, Sylvie, Valette, Martine, Launay, Odile, Lachatre, Marie, Lenzi, Nezha, L'Honneur, Anne-Sophie, Galtier, Florence, Olivier, Gaget Olivier, Foulongne, Vincent, Merle, Corinne, Vanhems, Philippe, Laine, Fabrice, Lagathu, Gisele, Carrat, Fabrice, Valenciano, Marta, Kissling, Esther, Rose, Angela, Penttinen, Pasi, Buda, Silke, Preuss, Ute, Tolksdorf, Kristin, Biere, Barbara, Duerrwald, Ralf, Smallfield, Maria, Wedde, Marianne, Domegan, Lisa, Hunt, Meadhbh, O'Donnell, Joan, Joyce, Michael, Levis, Olga, Collins, Claire, Dunford, Linda, Moran, Joanne, Tuite, Grainne, Connell, Jeff, de Gascun, Cillian, Casado, Itziar, Fernandino, Leticia, Martinez-Baz, Ivan, Juanbeltz, Regna, Ibanez, Carlos Gomez, Aguinaga, Aitziber, Ezpeleta, Carmen, Meijer, Adam, van der Hoek, Wim, Bagheri, Mariam, van den Brink, Sharon, Dijkstra, Frederika, Goderski, Gabriel, de lange, Marit, Marzec, Ton, Overduin, Pieter, Poorter, Elsa, Reukers, Daphne, Teirlinck, Anne Carola, Wijsman, Lisa, Donker, Ge, Hooiveld, Mariette, Gomez, Veronica, Kislaya, Irina, Machado, Ausenda, Nunes, Baltazar, Paula Rodrigues, Ana, Conde, Patricia, Costa, Ines, Cristovao, Paula, Guiomar, Raquel, Pechirra, Pedro, Lazar, Mihaela, Cherciu, Carmen Maria, Mihai, Maria Elena, Stoian, Elena, Dragomirescu, Cerasella, Popa, Mircea Ioan, Juganariu, Gabriela, Gradinaru, Maria, Loghin, Izabela, Vlad, Liliana, Duca, Elena, Hurmuzache, Mihnea, Dorobat, Carmen, Tardei, Gratela, Melinte, Violeta, Zaharia, Mihaela, Popescu, Corneliu Petru, Ceausu, Emanoil, Florescu, Simin-Aysel, Gherasim, Alin, Garcia Comas, Luis, Insua Marisquerena, Maria Esther, Galan, Juan Carlos, Dolores Folgueira, Ma, Castilla, Jesus, Garcia Cenoz, Manuel, Navascues, Ana, Quinones Rubio, Carmen, Martinez Ochoa, Eva, Blasco, Miriam, Gimenez Duran, Jaume, Maria Vanrell, Juana, Reina, Jordi, Castrillejo, Daniel, Delgado, Concha, Oliva, Jesus, Larrauri, Amparo, Gherasim, Alin Manuel, Mazagatos, Clara, Pozo, Francisco, Casas, Inmaculada, Latorre, Miriam, Millan Lou, Maria Isabel, Maria Milagro, Ana, Aizpurua, Amaia, Cilla, Gustavo, Montes, Milagrosa, Brytting, Mia, Enkirch, Theresa, Carnahan, Annasara, Wiman, Asa, Pebody, Richard, Whitaker, Heather, Andrews, Nick, Ellis, Joanna, Marques, Diogo F. P., Cottrell, Simon, Reynolds, Arlene, Gunson, Rory, Shepherd, Samantha J., Thompson, Catherine, Galiano, Monica, Robertson, Chris, O'Doherty, Mark, Owens, Katie, Yonova, Ivelina, Moore, Catherine, Johnson, Jillian, de Lusignan, Simon, McMenamin, Jim, Zambon, Maria, European IVE Grp.

    Interim 2018/19 influenza vaccine effectiveness: six European studies, October 2018 to January 2019

    Eurosurveillance . 24(8): 2-14. Number of citations: 37

    [doi:10.2807/1560-7917.ES.2019.24.1900121]

  • Hemelaar J, Elangovan R, Yun J, Dickson-Tetteh L, Fleminger I, Kirtley S, Williams B, Gouws-Williams E, Ghys PD, WHO–UNAIDS Network for HIV Isolation Characterisation.

    Global and regional molecular epidemiology of HIV-1, 1990-2015: a systematic review, global survey, and trend analysis.

    LANCET INFECTIOUS DISEASES . 19(2): 143-155. Number of citations: 132

    [doi:10.1016/S1473-3099(18)30647-9]

  • Abodakpi H, Chang KT, Gao S, Sánchez-Díaz AM, Cantón R, Tam VH.

    Optimal Piperacillin-Tazobactam Dosing Strategies against Extended-Spectrum--Lactamase-Producing Enterobacteriaceae .

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 63(2): . Number of citations: 6

    [doi:10.1128/AAC.01906-18]

  • Barragán-Prada H, Ruiz-Hueso P, Tedim AP, González-Candelas F, Galán JC, Cantón R, Morosini MI.

    Emergence and dissemination of colistin-resistant Klebsiella pneumoniae isolates expressing OXA-48 plus CTX-M-15 in patients not previously treated with colistin in a Spanish university hospital.

    DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE . 93(2): 147-153. Number of citations: 3

    [doi:10.1016/j.diagmicrobio.2018.08.014]

  • Campos M, Capilla R, Naya F, Futami R, Coque T, Moya A, Fernandez-Lanza V, Cantón R, Sempere JM, Llorens C, Baquero F.

    Simulating Multilevel Dynamics of Antimicrobial Resistance in a Membrane Computing Model.

    Mbio . 10(1): . Number of citations: 17

    [doi:10.1128/mBio.02460-18]

  • Aravena C, Valencia B, Villegas A, Ortega M, Fernández R A, Araya R P, Saavedra A, del Campo R.

    Caracterización de cepas clínicas y ambientales de Salmonella enterica subsp. enterica serovar Heidelberg aisladas en Chile.

    REVISTA MEDICA DE CHILE . 147(1): 24-33. Number of citations: 3

    [doi:10.4067/S0034-98872019000100024]

  • Del Campo R, Martínez-García L, Sánchez-Díaz AM, Baquero F.

    Biology of Hand-to-Hand Bacterial Transmission.

    Microbiology spectrum . 7(1): . Number of citations: 4

    [doi:10.1128/microbiolspec.MTBP-0011-2016]

  • Ruppé E, Ghozlane A, Tap J, Pons N, Alvarez AS, Maziers N, Cuesta T, Hernando-Amado S, Clares I, Martínez JL, Coque TM, Baquero F, Lanza VF, Máiz L, Goulenok T, de Lastours V, Amor N, Fantin B, Wieder I, Andremont A, van Schaik W, Rogers M, Zhang X, Willems RJL, de Brevern AG, Batto JM, Blottière HM, Léonard P, Léjard V, Letur A, Levenez F, Weiszer K, Haimet F, Doré J, Kennedy SP, Ehrlich SD.

    Prediction of the intestinal resistome by a three-dimensional structure-based method.

    Nature Microbiology . 4(1): 112-123. Number of citations: 67

    [doi:10.1038/s41564-018-0292-6]

  • Pastor Ó, Guzmán-Lafuente P, Serna J, Muñoz-Hernández M, López Neyra A, García-Rozas P, García-Seisdedos D, Alcázar A, Lasunción MA, Busto R, Lamas Ferreiro A.

    A comprehensive evaluation of omega-3 fatty acid supplementation in cystic fibrosis patients using lipidomics.

    JOURNAL OF NUTRITIONAL BIOCHEMISTRY . 63: 197-205. Number of citations: 7

    [doi:10.1016/j.jnutbio.2018.09.026]

  • Díez-Aguilar M, Ekkelenkamp M, Morosini MI, Merino I, Caballero JD, Jones M, van Westreenen M, Tunney MM, Cantón R, Fluit AC.

    Antimicrobial susceptibility of non-fermenting Gram-negative pathogens isolated from cystic fibrosis patients.

    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS . 53(1): 84-88. Number of citations: 15

    [doi:10.1016/j.ijantimicag.2018.09.001]

  • García-Fernández S, García-Castillo M, Ruiz-Garbajosa P, Morosini MI, Bala Y, Zambardi G, Cantón R.

    Performance of CHROMID® Colistin R agar, a new chromogenic medium for screening of colistin-resistant Enterobacterales.

    DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE . 93(1): 1-4. Number of citations: 9

    [doi:10.1016/j.diagmicrobio.2018.07.008]

  • Botelho J, Roberts AP, León-Sampedro R, Grosso F, Peixe L.

    Carbapenemases on the move: it's good to be on ICEs.

    MOBILE DNA . 9: 37-37. Number of citations: 25

    [doi:10.1186/s13100-018-0141-4]

  • Diab-Cáceres L, Girón-Moreno RM, Pastor-Sanz MT, Quintana-Gallego E, Delgado-Pecellín I, Blanco-Aparicio M, Maiz L, García-Clemente MM, Luna-Paredes C, Mondéjar-López P, Ruiz-de-Valbuena M, Fernández O, Barrio M, González M, López-Neyra A, Cols-I-Roig M, Palou-Rotger A, Gómez-de-Terreros-Caro FJ.

    Compassionate Use of Lumacaftor/Ivacaftor in Cystic Fibrosis: Spanish Experience.

    ARCHIVOS DE BRONCONEUMOLOGIA . 54(12): 614-618. Number of citations: 5

    [doi:10.1016/j.arbres.2018.05.004]

  • Morte E, Tolmos M, Halperin A, Morosini MI, Cantón R, Hermida JM.

    Early prosthetic endocarditis caused by Stenotrophomonas maltophilia.

    Medecine et maladies infectieuses . 48(8): 543-546. Number of citations: 2

    [doi:10.1016/j.medmal.2018.09.004]

  • San Millan A, Toll-Riera M, Qi Q, Betts A, Hopkinson RJ, McCullagh J, MacLean RC.

    Integrative analysis of fitness and metabolic effects of plasmids in Pseudomonas aeruginosa PAO1.

    ISME JOURNAL . 12(12): 3014-3024. Number of citations: 44

    [doi:10.1038/s41396-018-0224-8]

  • San Millan A.

    Evolution of Plasmid-Mediated Antibiotic Resistance in the Clinical Context.

    TRENDS IN MICROBIOLOGY . 26(12): 978-985. Number of citations: 119

    [doi:10.1016/j.tim.2018.06.007]

  • Blázquez-Garrido RM, Cuchí-Burgos E, Martín-Salas C, Ruiz-Garbajosa P.

    Microbiological monitoring of medical devices after cleaning, disinfection and sterilisation.

    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA . 36(10): 657-661.

    [doi:10.1016/j.eimc.2017.09.012]