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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Piñeiro L, Galán JC, Vall-Mayans M.

    Infections caused by Chlamydia trachomatis (including lymphogranuloma venereum) and Mycoplasma genitalium.

    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA . 37(8): 525-534. Number of citations: 2

    [doi:10.1016/j.eimc.2019.01.014]

  • Palacios-Baena ZR, Delgado-Valverde M, Valiente Méndez A, Almirante B, Gómez-Zorrilla S, Borrell N, Corzo JE, Gurguí M, de la Calle C, García-Álvarez L, Ramos L, Gozalo M, Morosini MI, Molina J, Causse M, Pascual Á, Rodríguez-Baño J, REIPI/GEIRAS-SEIMC BACTERIEMIA-MIC group.

    Impact of de-escalation on prognosis of patients with bacteraemia due to Enterobacteriaceae: a post-hoc analysis from a multicenter prospective cohort.

    CLINICAL INFECTIOUS DISEASES . 69(6): 956-962. Number of citations: 11

    [doi:10.1093/cid/ciy1032]

  • MacLean RC, San Millan A.

    The evolution of antibiotic resistance.

    Science . 365(6458): 1082-1083. Number of citations: 94

    [doi:10.1126/science.aax3879]

  • Gomez-Sala, Beatriz, Munoz-Atienza, Estefania, Diep, Dzung B., Feito, Javier, del Campo, Rosa, Nes, Ingolf F., Herranz, Carmen, Hernandez, Pablo E., Cintas, Luis M..

    Biotechnological potential and in vitro safety assessment of Lactobacillus curvatus BCS35, a multibacteriocinogenic strain isolated from dry-salted cod (Gadus morhua)

    LWT-FOOD SCIENCE AND TECHNOLOGY . 112: . Number of citations: 1

    [doi:10.1016/j.lwt.2019.05.117]

  • Sánchez-López J, Cantón R.

    Current status of ESKAPE microorganisms in Spain: Epidemiology and resistance phenotypes.

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 32 Suppl 2: 27-31. Number of citations: 7

  • Hernando-Amado S, Coque TM, Baquero F, Martínez JL.

    Defining and combating antibiotic resistance from One Health and Global Health perspectives.

    Nature Microbiology . 4(9): 1432-1442. Number of citations: 256

    [doi:10.1038/s41564-019-0503-9]

  • Morosini MI, Díez-Aguilar M, Cantón R.

    Mechanisms of action and antimicrobial activity of ceftobiprole.

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 32 Suppl 3: 3-10. Number of citations: 15

  • León-Sampedro R, Fernández-de-Bobadilla MD, San Millán Á, Baquero F, Coque TM.

    Transfer dynamics of Tn6648, a composite integrative conjugative element generated by tandem accretion of Tn5801 and Tn6647 in Enterococcus faecalis.

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 74(9): 2517-2523. Number of citations: 6

    [doi:10.1093/jac/dkz239]

  • Avendaño-Ortiz J, Llanos-González E, Toledano V, Del Campo R, Cubillos-Zapata C, Lozano-Rodríguez R, Ismail A, Prados C, Gómez-Campelo P, Aguirre LA, García-Río F, López-Collazo E.

    Pseudomonas aeruginosa colonization causes PD-L1 overexpression on monocytes, impairing the adaptive immune response in patients with cystic fibrosis.

    JOURNAL OF CYSTIC FIBROSIS . 18(5): 630-635. Number of citations: 9

    [doi:10.1016/j.jcf.2018.11.002]

  • Muñoz L, Borrero MJ, Úbeda M, Conde E, Del Campo R, Rodríguez-Serrano M, Lario M, Sánchez-Díaz AM, Pastor O, Díaz D, García-Bermejo L, Monserrat J, Álvarez-Mon M, Albillos A.

    Intestinal Immune Dysregulation Driven by Dysbiosis Promotes Barrier Disruption and Bacterial Translocation in Rats With Cirrhosis.

    HEPATOLOGY . 70(3): 925-938. Number of citations: 48

    [doi:10.1002/hep.30349]

  • Moles L, Gómez M, Moroder E, Jiménez E, Escuder D, Bustos G, Melgar A, Villa J, Del Campo R, Chaves F, Rodríguez JM.

    Serratia marcescens colonization in preterm neonates during their neonatal intensive care unit stay.

    Antimicrobial Resistance and Infection Control . 8(1): 135-135. Number of citations: 10

    [doi:10.1186/s13756-019-0584-5]

  • Nadal-Serrano JM, Gomez G de la Pedrosa E, Lopez-Vallejo M, de Guzmán Fernández González A, Lopez-Barrio C.

    Simple method to generate calibrated synthetic smoke-like atmospheres at microscopic scale.

    Plos One . 14(8): . Number of citations: 1

    [doi:10.1371/journal.pone.0220700]

  • Calvo-Lerma J, Hulst J, Boon M, Martins T, Ruperto M, Colombo C, Fornés-Ferrer V, Woodcock S, Claes I, Asseiceira I, Garriga M, Bulfamante A, Masip E, Walet S, Crespo P, Valmarana L, Martínez-Barona S, Pereira L, de Boeck K, Ribes-Koninckx C.

    The Relative Contribution of Food Groups to Macronutrient Intake in Children with Cystic Fibrosis: A European Multicenter Assessment.

    JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS . 119(8): 1305-1319. Number of citations: 15

    [doi:10.1016/j.jand.2019.01.003]

  • Aragonés N, Fernández de Larrea N, Pastor-Barriuso R, Michel A, Romero B, Pawlita M, Mayorgas-Torralba S, Martín V, Moreno V, Casabonne D, Castilla J, Fernandez-Tardón G, Dierssen-Sotos T, Capelo R, Salas D, Salcedo-Bellido I, Chirlaque MD, Brenner N, Pedraza M, Bessa X, Pérez-Gómez B, Butt J, Kogevinas M, Del Campo R, de Sanjosé S, Waterboer T, Pollán M.

    Epstein Barr virus antibody reactivity and gastric cancer: A population-based case-control study.

    CANCER EPIDEMIOLOGY . 61: 79-88. Number of citations: 3

    [doi:10.1016/j.canep.2019.05.008]

  • León-Sampedro R, Del Campo R, Rodriguez-Baños M, Lanza VF, Pozuelo MJ, Francés-Cuesta C, Tedim AP, Freitas AR, Novais C, Peixe L, Willems RJL, Corander J, González Candelas F, Baquero F, Coque TM.

    Phylogenomics of Enterococcus faecalis from wild birds: new insights into host-associated differences in core and accessory genomes of the species.

    ENVIRONMENTAL MICROBIOLOGY . 21(8): 3046-3062. Number of citations: 5

    [doi:10.1111/1462-2920.14702]

  • Hernández-García M, Pérez-Viso B, León-Sampedro R, Navarro-San Francisco C, López-Fresneña N, Díaz-Agero C, Morosini MI, Ruiz-Garbajosa P, Cantón R.

    Outbreak of NDM-1+CTX-M-15+DHA-1-producing Klebsiella pneumoniae high-risk clone in Spain owing to an undetectable colonised patient from Pakistan.

    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS . 54(2): 233-239. Number of citations: 10

    [doi:10.1016/j.ijantimicag.2019.05.021]

  • Alcaide F, Trastoy R, Moure R, González-Bardanca M, Ambroa A, López M, Bleriot I, Blasco L, Fernandez-García L, Tato M, Bou G, Tomás M.

    Multiplex Real time PCR-short TUB assay for detection of the Mycobacterium tuberculosis complex in smear-negative clinical samples with low mycobacterial loads.

    JOURNAL OF CLINICAL MICROBIOLOGY . 57(8): .

    [doi:10.1128/JCM.00733-19]

  • Butt J, Fernández de Larrea N, Tjalsma H, Roelofs R, Kato I, Martín V, Pérez-Gómez B, Moreno V, Dierssen-Sotos T, Castilla J, Fernández-Tardón G, Amiano P, Salas D, Alguacil J, Jiménez-Moleón JJ, Huerta JM, de Sanjosé S, Del Campo R, Kogevinas M, Pollán M, Pawlita M, Waterboer T, Boleij A, Aragonés N.

    Antibody responses to flagellin C and Streptococcus gallolyticus pilus proteins in colorectal cancer.

    SCIENTIFIC REPORTS . 9(1): 10847-10847. Number of citations: 1

    [doi:10.1038/s41598-019-47347-6]