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Neurodegenerative diseases: therapy development

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  • Sagredo O, González S, Aroyo I, Pazos MR, Benito C, Lastres-Becker I, Romero JP, Tolón RM, Mechoulam R, Brouillet E, Romero J, Fernández-Ruiz J.

    Cannabinoid CB2 Receptor Agonists Protect the Striatum Against Malonate Toxicity: Relevance for Huntington's Disease

    Glia . 57(11): 1154-1167. Number of citations: 124

    [doi:10.1002/glia.20838]

  • Tolón RM, Núñez E, Pazos MR, Benito C, Castillo AI, Martínez-Orgado JA, Romero J.

    The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages

    BRAIN RESEARCH . 1283: 148-154. Number of citations: 94

    [doi:10.1016/j.brainres.2009.05.098]

  • Pazos MR, Sagredo O, Fernández-Ruiz J.

    The endocannabinoid system in Huntington's disease

    CURRENT PHARMACEUTICAL DESIGN . 14(23): 2317-2325. Number of citations: 57

    [doi:10.2174/138161208785740108]

  • Pazos MR, Tolón RM, Benito C, Rodríguez CF, Gorgojo JJ, Nevado M, Alvarez M, Arias F, Almodóvar F, Fernández MT, Lledó JL, González S, Fernández-Ruiz JJ, Romero J.

    Cannabinoid CB1 receptors are expressed by parietal cells of the human gastric mucosa

    JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY . 56(5): 511-516. Number of citations: 19

    [doi:10.1369/jhc.2008.950741]

  • Fernández-Ruiz J, Pazos MR, García-Arencibia M, Sagredo O, Ramos JA.

    Role of CB2 receptors in neuroprotective effects of cannabinoids

    MOLECULAR AND CELLULAR ENDOCRINOLOGY . 286(1-2, 1): 91-96. Number of citations: 89

    [doi:10.1016/j.mce.2008.01.001]

  • Sagredo O, García-Arencibia M, de Lago E, Finetti S, Decio A, Fernández-Ruiz J.

    Cannabinoids and neuroprotection in basal ganglia disorders

    MOLECULAR NEUROBIOLOGY . 36(1): 82-91. Number of citations: 71

    [doi:10.1007/s12035-007-0004-3]

  • García-Arencibia M, González S, de Lago E, Ramos JA, Mechoulam R, Fernández-Ruiz J.

    Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: Importance of antioxidant and cannabinoid receptor-independent properties

    BRAIN RESEARCH . 1134(1): 162-170. Number of citations: 206

    [doi:10.1016/j.brainres.2006.11.063]

  • GÓMEZ CAÑAS, MARÍA, FERNÁNDEZ RUIZ, JOSÉ JAVIER.

    Synthesis and pharmacological evaluation of new (E)- and (Z)-3-aryl-4-styryl-1H-pyrazoles as potential cannabinoid ligands

    Arkivoc . 2010: 226-247.

    [doi:10.3998/ark.5550190.0011.a19]