Neurodegenerative diseases: therapy development
Search for publications
Only original articles, editorials, guidelines.
-
Burgaz S, García C, Gómez-Cañas M, Rolland A, Muñoz E, Fernández-Ruiz J.
Neuroprotection with the Cannabidiol Quinone Derivative VCE-004.8 (EHP-101) against 6-Hydroxydopamine in Cell and Murine Models of Parkinson's Disease
Molecules . 26(11): . Number of citations: 6
-
Galan-Ganga, M., Rodriguez-Cueto, C., Merchan-Rubira, J., Hernandez, F., avila, J., Posada-Ayala, M., Lanciego, J. L., Luengo, E., Lopez, M. G., Rabano, A., Fernandez-Ruiz, J., Lastres-Becker, I..
Cannabinoid receptor CB2 ablation protects against TAU induced neurodegeneration
Acta neuropathologica communications . 9(1): 90-90. Number of citations: 14
-
Sanchez Montero, Jose Maria, Agis-Torres, Angel, Solano, David, Söllhuber M, Fernandez, Maria, Villaro, Wilma, Gomez-Canas, Maria, Garcia-Arencibia, Moises, Fernandez-Ruiz, Javier, Egea, Javier, Martín MI, Giron, Rocio.
Analogues of cannabinoids as multitarget drugs in the treatment of Alzheimer's disease
EUROPEAN JOURNAL OF PHARMACOLOGY . 895: 173875-173875. Number of citations: 7
-
Rodríguez-Cueto C, García-Toscano L, Santos-García I, Gómez-Almería M, Gonzalo-Consuegra C, Espejo-Porras F, Fernández-Ruiz J, de Lago E.
Targeting the CB2 receptor and other endocannabinoid elements to delay disease progression in amyotrophic lateral sclerosis
BRITISH JOURNAL OF PHARMACOLOGY . 178(6): 1373-1387. Number of citations: 11
-
Rojas, Pilar, Ramirez, Ana I., Cadena, Manuel, Fernandez-Albarral, Jose A., Salobrar-Garcia, Elena, Lopez-Cuenca, Ines, Santos-Garcia, Irene, de Lago, Eva, Urcelay-Segura, Jose L., Ramirez, Jose M., de Hoz, Rosa, Salazar, Juan J..
Retinal Ganglion Cell Loss and Microglial Activation in a SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 22(4): . Number of citations: 6
-
Satta, Valentina, Alonso, Cristina, Diez, Paula, Martin-Suarez, Soraya, Rubio, Marta, Encinas, Juan M., Fernandez-Ruiz, Javier, Sagredo, Onintza.
Neuropathological Characterization of a Dravet Syndrome Knock-In Mouse Model Useful for Investigating Cannabinoid Treatments
FRONTIERS IN MOLECULAR NEUROSCIENCE . 13: 602801-602801. Number of citations: 12
-
Burgaz, Sonia, Garcia, Concepcion, Gomez-Canas, Maria, Navarrete, Carmen, Garcia-Martin, Adela, Rolland, Alain, del Rio, Carmen, Casarejos, Maria J., Muñoz E, Gonzalo-Consuegra, Claudia, Muñoz E, Fernandez-Ruiz, Javier.
Neuroprotection with the cannabigerol quinone derivative VCE-003.2 and its analogs CBGA-Q and CBGA-Q-Salt in Parkinson's disease using 6-hydroxydopamine-lesioned mice
MOLECULAR AND CELLULAR NEUROSCIENCE . 110: 103583-103583. Number of citations: 11
-
Morales, Paula, Navarro, Gemma, Gomez-Autet, Marc, Redondo, Laura, Fernandez-Ruiz, Javier, Perez-Benito, Laura, Cordomi, Arnau, Pardo, Leonardo, Franco, Rafael, Jagerovic, Nadine.
Discovery of Homobivalent Bitopic Ligands of the Cannabinoid CB2 Receptor**
CHEMISTRY-A EUROPEAN JOURNAL . 26(68): 15839-15842. Number of citations: 15
-
Palomares, Belen, Garrido-Rodriguez, Martin, Gonzalo-Consuegra, Claudia, Gomez-Canas, Maria, Saen-oon, Suwipa, Soliva, Robert, Collado, Juan A., Fernandez-Ruiz, Javier, Morello, Gaetano, Calzado, Marco A., Appendino, Giovanni, Muñoz E.
Delta(9)-Tetrahydrocannabinolic acid alleviates collagen-induced arthritis: Role of PPAR gamma and CB(1)receptors
BRITISH JOURNAL OF PHARMACOLOGY . 177(17): 4034-4054. Number of citations: 9
-
Espadas, Isabel, Keifman, Ettel, Palomo-Garo, Cristina, Burgaz, Sonia, Garcia, Concepcion, Fernandez-Ruiz, Javier, Moratalla, Rosario.
Beneficial effects of the phytocannabinoid Delta(9)-THCV in L-DOPA-induced dyskinesia in Parkinson's disease
NEUROBIOLOGY OF DISEASE . 141: 104892-104892. Number of citations: 15
-
Fernandez-Ruiz, Javier, Galve-Roperh, Ismael, Sagredo, Onintza, Guzman, Manuel.
Possible therapeutic applications of cannabis in the neuropsychopharmacology field
EUROPEAN NEUROPSYCHOPHARMACOLOGY . 36: 217-234. Number of citations: 19
-
Martinez-Gonzalez, Loreto, Rodriguez-Cueto, Carmen, Cabezudo, Diego, Bartolome, Fernando, Andres-Benito, Pol, Ferrer, Isidro, Gil, Carmen, Martin-Requero, Angeles, Fernandez-Ruiz, Javier, Martinez, Ana, de Lago, Eva.
Motor neuron preservation and decrease of in vivo TDP-43 phosphorylation by protein CK-1 delta kinase inhibitor treatment
SCIENTIFIC REPORTS . 10(1): 4449-4449. Number of citations: 35
-
Fernandez-Trapero, Maria, Perez-Diaz, Carmen, Espejo-Porras, Francisco, de Lago, Eva, Fernandez-Ruiz, Javier.
Pharmacokinetics of Sativex (R) in Dogs: Towards a Potential Cannabinoid-Based Therapy for Canine Disorders
Biomolecules . 10(2): . Number of citations: 17
-
Götz MR, Collado JA, Fernández-Ruiz J, Fiebich BL, García-Toscano L, Gómez-Cañas M, Koch O, Leha A, Muñoz E, Navarrete C, Pazos MR, Holzgrabe U.
Structure-Effect Relationships of Novel Semi-Synthetic Cannabinoid Derivatives.
FRONTIERS IN PHARMACOLOGY . 10: 1284-1284. Number of citations: 5
-
Ceprián M, Vargas C, García-Toscano L, Penna F, Jiménez-Sánchez L, Achicallende S, Elezgarai I, Grandes P, Hind W, Pazos MR, Martínez-Orgado J.
Cannabidiol Administration Prevents Hypoxia-Ischemia-Induced Hypomyelination in Newborn Rats.
FRONTIERS IN PHARMACOLOGY . 10: 1131-1131. Number of citations: 16
-
Burgaz S, García C, Gómez-Cañas M, Muñoz E, Fernández-Ruiz J.
Development of An Oral Treatment with the PPAR-?-Acting Cannabinoid VCE-003.2 Against the Inflammation-Driven Neuronal Deterioration in Experimental Parkinson's Disease.
Molecules . 24(15): . Number of citations: 17
-
Ucha M, Coria SM, Núñez AE, Santos-Toscano R, Roura-Martínez D, Fernández-Ruiz J, Higuera-Matas A, Ambrosio E.
Morphine self-administration alters the expression of translational machinery genes in the amygdala of male Lewis rats.
JOURNAL OF PSYCHOPHARMACOLOGY . 33(7): 882-893. Number of citations: 6
-
Fernández-Ruiz J.
The biomedical challenge of neurodegenerative disorders: an opportunity for cannabinoid-based therapies to improve on the poor current therapeutic outcomes.
BRITISH JOURNAL OF PHARMACOLOGY . 176(10): 1370-1383. Number of citations: 31