Neurodegenerative diseases: therapy development
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Valdeolivas S, Navarrete C, Cantarero I, Bellido ML, Muñoz E, Sagredo O.
Neuroprotective Properties of Cannabigerol in Huntington's Disease: Studies in R6/2 Mice and 3-Nitropropionate-lesioned Mice
Neurotherapeutics . 12(1): 185-199. Number of citations: 67
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Ooms M, Rietjens R, Rangarajan JR, Vunckx K, Valdeolivas S, Maes F, Himmelreich U, Fernandez-Ruiz J, Bormans G, Van Laere K, Casteels C.
Early decrease of type 1 cannabinoid receptor binding and phosphodiesterase 10A activity in vivo in R6/2 Huntington mice
NEUROBIOLOGY OF AGING . 35(12): 2858-2869. Number of citations: 24
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Fernandes VS, Ribeiro AS, Martínez P, López-Oliva ME, Barahona MV, Orensanz LM, Martínez-Sáenz A, Recio P, Benedito S, Bustamante S, García-Sacristán A, Prieto D, Hernández M.
Hydrogen Sulfide Plays a Key Role in the Inhibitory Neurotransmission to the Pig Intravesical Ureter
Plos One . 9(11): . Number of citations: 19
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Calatrava-Ferreras L, Gonzalo-Gobernado R, Reimers D, Herranz AS, Jiménez-Escrig A, Díaz-Gil JJ, Casarejos MJ, Montero-Vega MT, Bazán E.
Neuroprotective Role of Liver Growth Factor ``LGF'' in an Experimental Model of Cerebellar Ataxia
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 15(10): 19056-19073. Number of citations: 4
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Casarejos MJ, Perucho J, López-Sendón JL, García de Yébenes J, Bettencourt C, Gómez A, Ruiz C, Heutink P, Rizzu P, Mena MA.
Trehalose Improves Human Fibroblast Deficits in a New CHIP-Mutation Related Ataxia
Plos One . 9(9): . Number of citations: 21
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Moreno-Martet M, Espejo-Porras F, Fernández-Ruiz J, de Lago E.
Changes in Endocannabinoid Receptors and Enzymes in the Spinal Cord of SOD1(G93A) Transgenic Mice and Evaluation of a Sativex (R)-like Combination of Phytocannabinoids: Interest for Future Therapies in Amyotrophic Lateral Sclerosis
CNS NEUROSCIENCE & THERAPEUTICS . 20(9): 809-815. Number of citations: 37
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Moreno E, Andradas C, Medrano M, Caffarel MM, Pérez-Gómez E, Blasco-Benito S, Gómez-Cañas M, Pazos MR, Irving AJ, Lluís C, Canela EI, Fernández-Ruiz J, Guzmán M, McCormick PJ, Sánchez C.
Targeting CB2-GPR55 Receptor Heteromers Modulates Cancer Cell Signaling
JOURNAL OF BIOLOGICAL CHEMISTRY . 289(32): 21960-21972. Number of citations: 71
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Chiarlone A, Bellocchio L, Blázquez C, Resel E, Soria-Gómez E, Cannich A, Ferrero JJ, Sagredo O, Benito C, Romero J, Sánchez-Prieto J, Lutz B, Fernández-Ruiz J, Galve-Roperh I, Guzmán M.
A restricted population of CB1 cannabinoid receptors with neuroprotective activity
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA . 111(22): 8257-8262. Number of citations: 109
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Ribeiro AS, Fernandes VS, Martínez MP, Martínez-Sáenz A, Pazos MR, Orensanz LM, Recio P, Bustamante S, Carballido J, García-Sacristán A, Prieto D, Hernández M.
Neuronal and non-neuronal bradykinin receptors are involved in the contraction and/or relaxation to the pig bladder neck smooth muscle
NEUROUROLOGY AND URODYNAMICS . 33(5): 558-565. Number of citations: 3
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Devinsky O, Cilio MR, Cross H, Fernandez-Ruiz J, French J, Hill C, Katz R, Di Marzo V, Jutras-Aswad D, Notcutt WG, Martinez-Orgado J, Robson PJ, Rohrback BG, Thiele E, Whalley B, Friedman D.
Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders
Epilepsia . 55(6): 791-802. Number of citations: 502
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Rodríguez-Cueto C, Benito C, Fernández-Ruiz J, Romero J, Hernández-Gálvez M, Gómez-Ruiz M.
Changes in CB1 and CB2 receptors in the post- mortem cerebellum of humans affected by spinocerebellar ataxias
BRITISH JOURNAL OF PHARMACOLOGY . 171(6, SI): 1472-1489. Number of citations: 39
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Fernandez-Estevez MA, Casarejos MJ, López Sendon J, Garcia Caldentey J, Ruiz C, Gomez A, Perucho J, de Yebenes JG, Mena MA.
Trehalose Reverses Cell Malfunction in Fibroblasts from Normal and Huntington's Disease Patients Caused by Proteosome Inhibition
Plos One . 9(2): . Number of citations: 43
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González-Naranjo P, Pérez-Macias N, Campillo NE, Pérez C, Arán VJ, Girón R, Sánchez-Robles E, Martín MI, Gómez-Cañas M, García-Arencibia M, Fernández-Ruiz J, Páez JA.
Cannabinoid agonists showing BuChE inhibition as potential therapeutic agents for Alzheimer's disease
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY . 73: 56-72. Number of citations: 36
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Gonzalo-Gobernado R, Calatrava-Ferreras L, Perucho J, Reimers D, Casarejos MJ, Herranz AS, Jimenez-Escrig A, Diaz-Gil JJ, Bazan E.
Liver growth factor as a tissue regenerating factor in neurodegenerative diseases.
Recent patents on CNS drug discovery . 9(3): 173-180.
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Rodríguez-Cueto C, Benito C, Romero J, Hernández-Gálvez M, Gómez-Ruiz M, Fernández-Ruiz J.
Endocannabinoid-Hydrolysing Enzymes in the Post-Mortem Cerebellum of Humans Affected by Hereditary Autosomal Dominant Ataxias
Pathobiology . 81(3): 149-159. Number of citations: 9
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Fernández-Fernández C, Callado LF, Girón R, Sánchez E, Erdozain AM, López-Moreno JA, Morales P, Rodríguez de Fonseca F, Fernández-Ruiz J, Goya P, Meana JJ, Martín MI, Jagerovic N.
Combining rimonabant and fentanyl in a single entity: preparation and pharmacological results
DRUG DESIGN DEVELOPMENT AND THERAPY . 8: 263-277. Number of citations: 14
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Morales P, Vara D, Goméz-Cañas M, Zúñiga MC, Olea-Azar C, Goya P, Fernández-Ruiz J, Díaz-Laviada I, Jagerovic N.
Synthetic cannabinoid quinones: Preparation, in vitro antiproliferative effects and in vivo prostate antitumor activity
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY . 70: 111-119. Number of citations: 28
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Espejo-Porras F, Fernández-Ruiz J, Pertwee RG, Mechoulam R, García C.
Motor effects of the non-psychotropic phytocannabinoid cannabidiol that are mediated by 5-HT1A receptors
Neuropharmacology . 75(SI): 155-163. Number of citations: 43