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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Cantón R, Ruiz-Garbajosa P.

    Co-resistance: an opportunity for the bacteria and resistance genes

    CURRENT OPINION IN PHARMACOLOGY . 11(5): 477-485. Number of citations: 115

    [doi:10.1016/j.coph.2011.07.007]

  • Romero B, Morosini MI, Loza E, Rodríguez-Baños M, Navas E, Cantón R, Campo RD.

    Reidentification of Streptococcus bovis Isolates Causing Bacteremia According to the New Taxonomy Criteria: Still an Issue?

    JOURNAL OF CLINICAL MICROBIOLOGY . 49(9): 3228-3233. Number of citations: 63

    [doi:10.1128/JCM.00524-11]

  • Riera E, Cabot G, Mulet X, García-Castillo M, del Campo R, Juan C, Cantón R, Oliver A.

    Pseudomonas aeruginosa carbapenem resistance mechanisms in Spain: impact on the activity of imipenem, meropenem and doripenem

    The Journal of antimicrobial chemotherapy . 66(9): 2022-2027. Number of citations: 101

    [doi:10.1093/jac/dkr232]

  • Cantón R, Morosini MI.

    Emergence and spread of antibiotic resistance following exposure to antibiotics

    FEMS MICROBIOLOGY REVIEWS . 35(5, SI): 977-991. Number of citations: 177

    [doi:10.1111/j.1574-6976.2011.00295.x]

  • Navarro F, Calvo J, Cantón R, Fernández-Cuenca F, Mirelis B.

    Detection of resistance phenotypes in gram-negative bacteria

    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA . 29(7): 524-534. Number of citations: 16

    [doi:10.1016/j.eimc.2011.03.011]

  • García-Castillo M, Del Campo R, Morosini MI, Riera E, Cabot G, Willems R, van Mansfeld R, Oliver A, Cantón R.

    Wide dispersion of ST175 clone despite high genetic diversity of carbapenem-nonsusceptible Pseudomonas aeruginosa clinical strains in 16 Spanish hospitals.

    JOURNAL OF CLINICAL MICROBIOLOGY . 49(8): 2905-2910. Number of citations: 70

    [doi:10.1128/JCM.00753-11]

  • Freitas AR, Novais C, Correia R, Monteiro M, Coque TM, Peixe L.

    Non-susceptibility to tigecycline in enterococci from hospitalised patients, food products and community sources.

    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS . 38(2): 174-176. Number of citations: 18

    [doi:10.1016/j.ijantimicag.2011.04.014]

  • Baquero F.

    The 2010 Garrod Lecture: the dimensions of evolution in antibiotic resistance: ex unibus plurum et ex pluribus unum.

    The Journal of antimicrobial chemotherapy . 66(8): 1659-1672. Number of citations: 35

    [doi:10.1093/jac/dkr214]

  • Baquero F, Coque TM, de la Cruz F.

    Ecology and evolution as targets: the need for novel eco-evo drugs and strategies to fight antibiotic resistance.

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 55(8): 3649-3660. Number of citations: 129

    [doi:10.1128/AAC.00013-11]

  • Ledesma J, Vicente D, Pozo F, Cilla G, Castro SP, Fernández JS, Ruiz MP, Navarro JM, Galán JC, Fernández M, Reina J, Larrauri A, Cuevas MT, Casas I, Breña PP.

    Oseltamivir-resistant pandemic influenza a (H1N1) 2009 viruses in Spain

    JOURNAL OF CLINICAL VIROLOGY . 51(3): 205-208. Number of citations: 4

    [doi:10.1016/j.jcv.2011.04.008]

  • Delgado S, García P, Fernández L, Jiménez E, Rodríguez-Baños M, del Campo R, Rodríguez JM.

    Characterization of Staphylococcus aureus strains involved in human and bovine mastitis

    FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY . 62(2): 225-235. Number of citations: 50

    [doi:10.1111/j.1574-695X.2011.00806.x]

  • Andrade LN, Curiao T, Ferreira JC, Longo JM, Clímaco EC, Martinez R, Bellissimo-Rodrigues F, Basile-Filho A, Evaristo MA, Del Peloso PF, Ribeiro VB, Barth AL, Paula MC, Baquero F, Cantón R, Darini AL, Coque TM.

    Dissemination of blaKPC-2 by the spread of Klebsiella pneumoniae clonal complex 258 clones (ST258, ST11, ST437) and plasmids (IncFII, IncN, IncL/M) among Enterobacteriaceae species in Brazil.

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 55(7): 3579-3583. Number of citations: 145

    [doi:10.1128/AAC.01783-10]

  • Kechrid A, Pérez-Vázquez M, Smaoui H, Hariga D, Rodríguez-Baños M, Vindel A, Baquero F, Cantón R, Del Campo R.

    Molecular analysis of community-acquired methicillin-susceptible and resistant Staphylococcus aureus isolates recovered from bacteraemic and osteomyelitis infections in children from Tunisia.

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases . 17(7): 1020-1026. Number of citations: 31

    [doi:10.1111/j.1469-0691.2010.03367.x]

  • Read RC, Cornaglia G, Kahlmeter G.

    Professional challenges and opportunities in clinical microbiology and infectious diseases in Europe.

    LANCET INFECTIOUS DISEASES . 11(5): 408-415. Number of citations: 35

    [doi:10.1016/S1473-3099(10)70294-2]

  • Rodríguez-Avial I, Ramos B, Rios E.

    Clonal Spread of Levofloxacin-Resistant Streptococcus pneumoniae Invasive Isolates in Madrid, Spain, 2007 to 2009

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 55(5): 2469-2471. Number of citations: 23

    [doi:10.1128/AAC.01380-10]

  • Nordmann P, Picazo JJ, Mutters R.

    Comparative activity of carbapenem testing: the COMPACT study

    The Journal of antimicrobial chemotherapy . 66(5): 1070-1078. Number of citations: 30

    [doi:10.1093/jac/dkr056]

  • Ruiz SJ, Montealegre MC, Ruiz-Garbajosa P, Correa A, Briceño DF, Martinez E, Rosso F, Muñoz M, Quinn JP, Cantón R, Villegas MV.

    First Characterization of CTX-M-15-Producing Escherichia coli ST131 and ST405 Clones Causing Community-Onset Infections in South America

    JOURNAL OF CLINICAL MICROBIOLOGY . 49(5): 1993-1996. Number of citations: 39

    [doi:10.1128/JCM.00045-11]

  • Ledesma J, Pozo F, Pérez Ruiz M, Navarro JM, Piñeiro L, Montes M, Pérez Castro S, Suárez Fernández J, García Costa J, Fernández M, Galán JC, Cuevas MT, Casas I, Pérez Breña P.

    Substitutions in position 222 of haemagglutinin of pandemic influenza A (H1N1) 2009 viruses in Spain

    JOURNAL OF CLINICAL VIROLOGY . 51(1): 75-78. Number of citations: 26

    [doi:10.1016/j.jcv.2011.01.020]