Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Freitas AR, Tedim AP, Novais C, Ruiz-Garbajosa P, Werner G, Laverde-Gomez JA, Cantón R, Peixe L, Baquero F, Coque TM.

    Global spread of the hyl(Efm) colonization-virulence gene in megaplasmids of the Enterococcus faecium CC17 polyclonal subcluster.

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 54(6): 2660-2665. Number of citations: 56

    [doi:10.1128/AAC.00134-10]

  • Cantón R, Ruiz-Garbajosa P, Chaves RL, Johnson AP.

    A potential role for daptomycin in enterococcal infections: what is the evidence?

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 65(6): 1126-1136. Number of citations: 65

    [doi:10.1093/jac/dkq087]

  • Lamas A, López-Herce J.

    Monitoring sedation in the critically ill child

    Anaesthesia . 65(5): 516-524. Number of citations: 10

    [doi:10.1111/j.1365-2044.2010.06263.x]

  • Turrientes MC, Baquero MR, Sánchez MB, Valdezate S, Escudero E, Berg G, Cantón R, Baquero F, Galán JC, Martínez JL.

    Polymorphic mutation frequencies of clinical and environmental Stenotrophomonas maltophilia populations.

    APPLIED AND ENVIRONMENTAL MICROBIOLOGY . 76(6): 1746-1758. Number of citations: 51

    [doi:10.1128/AEM.02817-09]

  • Miriagou V, Cornaglia G, Edelstein M, Galani I, Giske CG, Gniadkowski M, Malamou-Lada E, Martinez-Martinez L, Navarro F, Nordmann P, Peixe L, Pournaras S, Rossolini GM, Tsakris A, Vatopoulos A, Cantón R.

    Acquired carbapenemases in Gram-negative bacterial pathogens: detection and surveillance issues

    CLINICAL MICROBIOLOGY AND INFECTION . 16(2): 112-122. Number of citations: 241

    [doi:10.1111/j.1469-0691.2009.03116.x]

  • Novais A, Comas I, Baquero F, Cantón R, Coque TM, Moya A, González-Candelas F, Galán JC.

    Evolutionary trajectories of beta-lactamase CTX-M-1 cluster enzymes: predicting antibiotic resistance.

    PLOS PATHOGENS . 6(1): . Number of citations: 84

    [doi:10.1371/journal.ppat.1000735]

  • Bofarull AM, Royo AA, Fernández MH, Ortiz-Jaureguizar E, Morales J.

    Influence of continental history on the ecological specialization and macroevolutionary processes in the mammalian assemblage of South America: Differences between small and large mammals

    BMC EVOLUTIONARY BIOLOGY . 8: 97-97. Number of citations: 31

    [doi:10.1186/1471-2148-8-97]

  • Bertagnolio S, Dobreva Z, Centner CM, Olaru ID, Donà D, Burzo S, Huttner BD, Chaillon A, Gebreselassie N, Wi T, Hasso-Agopsowicz M, Allegranzi B, Sati H, Ivanovska V, Kothari KU, Balkhy HH, Cassini A, Hamers RL, Weezenbeek KV.

    WHO global research priorities for antimicrobial resistance in human health.

    The Lancet. Microbe . : 100902-100902.

    [doi:10.1016/S2666-5247(24)00134-4]

  • Sastre-Dominguez J, DelaFuente J, Toribio-Celestino L, Herencias C, Herrador-Gómez P, Costas C, Hernández-García M, Cantón R, Rodríguez-Beltrán J, Santos-Lopez A, San Millan A.

    Plasmid-encoded insertion sequences promote rapid adaptation in clinical enterobacteria.

    Nature Ecology & Evolution . : .

    [doi:10.1038/s41559-024-02523-4]

  • de Lorenzo V, Baquero F, Aguilar A.

    Carlos Asensio and the dawn of molecular microbial ecology.

    INTERNATIONAL MICROBIOLOGY . : .

    [doi:10.1007/s10123-024-00596-6]

  • De La Villa S, Escrihuela-Vidal F, Fernández-Hidalgo N, Escudero-Sánchez R, Cabezón I, Boix-Palop L, Díaz-Pollán B, Goikoetxea AJ, García-País MJ, Pérez-Rodríguez MT, Crespo Á, Buzón-Martín L, Sanz-Peláez O, Ramos-Merino L, Silvante F, Muñoz P.

    Ceftaroline for bloodstream infections caused by methicillin-resistant Staphylococcus aureus: a multicentre retrospective cohort study.

    CLINICAL MICROBIOLOGY AND INFECTION . : .

    [doi:10.1016/j.cmi.2024.11.022]

  • Vicente-Santamaría S, Torres-Guerrero ME, García-González M, Tabares-González A, Gascón-Galindo C, López-Cárdenes CM, Blitz-Castro E, Morales-Tirado A, Mota Goitia MI, Gutiérrez Martínez JR, Tutau Gómez C, García Romero R, Salcedo Lobato E, Peña Quintana L, Reyes Domínguez A, Torcuato Rubio E, Ortiz Pérez P, Fernández-Lorenzo AE, Moreno Álvarez A, Boga AS, Romero Rey H, Álvarez Beltrán M, Masip Simo E, González Jiménez D.

    Assessment of cystic fibrosis related liver disease in a pediatric cohort.

    GASTROENTEROLOGIA Y HEPATOLOGIA . : 502321-502321.

    [doi:10.1016/j.gastrohep.2024.502321]

  • Mangas-Sánchez C, Garriga-García M, Serrano-Nieto MJ, Garcia-Romero R, Álvarez Beltrán M, Crehuá-Gaudiza E, Vicente-Santamaría S, Martínez-Costa C, Díaz-Martín JJ, Bousoño-García C, González-Jiménez D.

    Safety and efficacy of a new supplementation protocol in patients with cystic fibrosis and vitamin D deficiency.

    Anales De Pediatria . : .

    [doi:10.1016/j.anpede.2023.02.015]

  • Roca M, Masip E, Colombo C, Boon M, Hulst JM, Garriga M, de Koning BAE, Bulfamante A, de Boeck K, Ribes-Koninckx C, Calvo-Lerma J.

    Long-term evaluation of faecal calprotectin levels in a European cohort of children with cystic fibrosis.

    ARCHIVES OF DISEASE IN CHILDHOOD . : .

    [doi:10.1136/archdischild-2023-326221]

  • Piñeiro Pérez R, Santiago García B, Fernández Llamazares CM, Baquero Artigao F, Noguera Julian A, Mellado Peña MJ, en representación de pTBred (Red Española de Estudio de Tuberculosis Pediátrica).

    [The challenge of administering anti-tuberculosis treatment in infants and pre-school children. pTBred Magistral Project].

    ANALES DE PEDIATRIA . : .

    [doi:10.1016/j.anpedi.2015.07.027]

  • De la Calle M, Baquero F, Rodriguez R, González M, Fernández A, Omeñaca F, Bartha JL.

    Successful treatment of intrauterine cytomegalovirus infection with an intraventricular cyst in a dichorionic diamniotic twin gestation using cytomegalovirus immunoglobulin.

    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians . : 1-4.

    [doi:10.1080/14767058.2017.1338259]

  • Braojos F, Fuentes I, Saugar JM, Martín O, López-Vélez R, Norman FF.

    Amebic abscess and sexual contact.

    JOURNAL OF TRAVEL MEDICINE . : .

    [doi:10.1093/jtm/taab089]

  • Zvezdanova ME, Arroyo MJ, Méndez G, Candela A, Mancera L, Rodríguez JG, Serra JL, Jiménez R, Lozano I, Castro C, López C, Muñoz P, Guinea J, Escribano P, Rodríguez-Sánchez B, ASPEIN group.

    Detection of azole resistance in Aspergillus fumigatus complex isolates using MALDI-TOF mass spectrometry.

    CLINICAL MICROBIOLOGY AND INFECTION . : .

    [doi:10.1016/j.cmi.2021.06.005]