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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

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Only original articles, editorials, guidelines.

  • Martínez García MÁ, Máiz Carro L, Catalán Serra P.

    Treatment of Non-Cystic Fibrosis Bronchiectasis

    ARCHIVOS DE BRONCONEUMOLOGIA . 47(12): 599-609. Number of citations: 13

    [doi:10.1016/j.arbres.2011.06.003]

  • Cantón R, Loza E, Aznar J, Calvo J, Cercenado E, Cisterna R, Romo FG, Hontangas JL, Calvo CR, Barrenechea AI, Tubau F, Weber I, Yuste P, Cavanillas R.

    Antimicrobial susceptibility of Gram-negative organisms from intraabdominal infections and evolution of isolates with extended spectrum ß-lactamases in the SMART study in Spain (2002-2010).

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 24(4): 223-232. Number of citations: 27

  • D'Auria G, Galán JC, Rodríguez-Alcayna M, Moya A, Baquero F, Latorre A.

    Complete genome sequence of Acidaminococcus intestini RYC-MR95, a Gram-negative bacterium from the phylum Firmicutes.

    JOURNAL OF BACTERIOLOGY . 193(24): 7008-7009. Number of citations: 12

    [doi:10.1128/JB.06301-11]

  • Cantón E, Pemán J, Quindós G, Eraso E, Miranda-Zapico I, Álvarez M, Merino P, Campos-Herrero I, Marco F, de la Pedrosa EG, Yagüe G, Guna R, Rubio C, Miranda C, Pazos C, Velasco D.

    Prospective Multicenter Study of the Epidemiology, Molecular Identification, and Antifungal Susceptibility of Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis Isolated from Patients with Candidemia

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 55(12): 5590-5596. Number of citations: 97

    [doi:10.1128/AAC.00466-11]

  • Holguin A, Banda M, Willen EJ, Malama C, Chiyenu KO, Mudenda VC, Wood C.

    HIV-1 effects on neuropsychological performance in a resource-limited country, Zambia.

    AIDS AND BEHAVIOR . 15(8): 1895-1901. Number of citations: 36

    [doi:10.1007/s10461-011-9988-9]

  • Yebra G, de Mulder M, Pérez-Elías MJ, Pérez-Molina JA, Galán JC, Llenas-García J, Moreno S, Holguín Á.

    Increase of transmitted drug resistance among HIV-infected sub-Saharan Africans residing in Spain in contrast to the native population.

    Plos One . 6(10): . Number of citations: 27

    [doi:10.1371/journal.pone.0026757]

  • Bou G, Fernández-Olmos A, García C, Sáez-Nieto JA, Valdezate S.

    Bacterial identification methods in the microbiology laboratory

    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA . 29(8): 601-608. Number of citations: 23

    [doi:10.1016/j.eimc.2011.03.012]

  • Martín-Frías M, Máiz L, Carcavilla A, Barrio R.

    Long-term benefits in lung function and nutritional status of strict metabolic control of cystic fibrosis-related diabetes

    ARCHIVOS DE BRONCONEUMOLOGIA . 47(10): 531-534. Number of citations: 4

    [doi:10.1016/j.arbres.2011.06.004]

  • Ripoll A, Baquero F, Novais A, Rodríguez-Domínguez MJ, Turrientes MC, Cantón R, Galán JC.

    In vitro selection of variants resistant to beta-lactams plus beta-lactamase inhibitors in CTX-M beta-lactamases: predicting the in vivo scenario?

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 55(10): 4530-4536. Number of citations: 34

    [doi:10.1128/AAC.00178-11]

  • Martínez JL, Baquero F, Andersson DI.

    Beyond serial passages: new methods for predicting the emergence of resistance to novel antibiotics.

    CURRENT OPINION IN PHARMACOLOGY . 11(5): 439-445. Number of citations: 59

    [doi:10.1016/j.coph.2011.07.005]

  • González-Alba JM, Holguín A, Garcia R, García-Bujalance S, Alonso R, Suárez A, Delgado R, Cardeñoso L, González R, García-Bermejo I, Portero F, de Mendoza C, González-Candelas F, Galán JC.

    Molecular surveillance of HIV-1 in Madrid, Spain: a phylogeographic analysis.

    JOURNAL OF VIROLOGY . 85(20): 10755-10763. Number of citations: 33

    [doi:10.1128/JVI.00454-11]

  • de Mulder M, Yebra G, Martín L, Prieto L, Mellado MJ, Rojo P, Muñoz-Fernández MÁ, Jiménez de Ory S, Ramos JT, Holguín A.

    Drug resistance prevalence and HIV-1 variant characterization in the naive and pretreated HIV-1-infected paediatric population in Madrid, Spain.

    The Journal of antimicrobial chemotherapy . 66(10): 2362-2371. Number of citations: 17

    [doi:10.1093/jac/dkr305]

  • Cantón R, Ruiz-Garbajosa P.

    Co-resistance: an opportunity for the bacteria and resistance genes

    CURRENT OPINION IN PHARMACOLOGY . 11(5): 477-485. Number of citations: 115

    [doi:10.1016/j.coph.2011.07.007]

  • Romero B, Morosini MI, Loza E, Rodríguez-Baños M, Navas E, Cantón R, Campo RD.

    Reidentification of Streptococcus bovis Isolates Causing Bacteremia According to the New Taxonomy Criteria: Still an Issue?

    JOURNAL OF CLINICAL MICROBIOLOGY . 49(9): 3228-3233. Number of citations: 63

    [doi:10.1128/JCM.00524-11]

  • Riera E, Cabot G, Mulet X, García-Castillo M, del Campo R, Juan C, Cantón R, Oliver A.

    Pseudomonas aeruginosa carbapenem resistance mechanisms in Spain: impact on the activity of imipenem, meropenem and doripenem

    The Journal of antimicrobial chemotherapy . 66(9): 2022-2027. Number of citations: 101

    [doi:10.1093/jac/dkr232]

  • Cantón R, Morosini MI.

    Emergence and spread of antibiotic resistance following exposure to antibiotics

    FEMS MICROBIOLOGY REVIEWS . 35(5, SI): 977-991. Number of citations: 177

    [doi:10.1111/j.1574-6976.2011.00295.x]

  • Navarro F, Calvo J, Cantón R, Fernández-Cuenca F, Mirelis B.

    Detection of resistance phenotypes in gram-negative bacteria

    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA . 29(7): 524-534. Number of citations: 16

    [doi:10.1016/j.eimc.2011.03.011]

  • García-Castillo M, Del Campo R, Morosini MI, Riera E, Cabot G, Willems R, van Mansfeld R, Oliver A, Cantón R.

    Wide dispersion of ST175 clone despite high genetic diversity of carbapenem-nonsusceptible Pseudomonas aeruginosa clinical strains in 16 Spanish hospitals.

    JOURNAL OF CLINICAL MICROBIOLOGY . 49(8): 2905-2910. Number of citations: 70

    [doi:10.1128/JCM.00753-11]