1. Home
  2. Research
  3. Research Groups
  4. Biology and Evolution of Microorganisms

Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Friaza V, la Horra Cd, Rodríguez-Domínguez MJ, Martín-Juan J, Cantón R, Calderón EJ, Del Campo R.

    Metagenomic analysis of bronchoalveolar lavage samples from patients with idiopathic interstitial pneumonia and its antagonic relation with Pneumocystis jirovecii colonization

    JOURNAL OF MICROBIOLOGICAL METHODS . 82(1): 98-101. Number of citations: 26

    [doi:10.1016/j.mimet.2010.03.026]

  • Pfaller MA, Diekema DJ, Gibbs DL, Newell VA, Barton R, Bijie H, Bille J, Chang SC, da Luz Martins M, Duse A, Dzierzanowska D, Ellis D, Finquelievich J, Gould I, Gur D, Hoosen A, Lee K, Mallatova N, Mallie M, Peng NG, Petrikos G, Santiago A, Trupl J, VanDen Abeele AM, Wadula J, Zaidi M.

    Geographic variation in the frequency of isolation and fluconazole and voriconazole susceptibilities of Candida glabrata: an assessment from the ARTEMIS DISK Global Antifungal Surveillance Program

    DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE . 67(2): 162-171. Number of citations: 62

    [doi:10.1016/j.diagmicrobio.2010.01.002]

  • Hegstad K, Mikalsen T, Coque TM, Werner G, Sundsfjord A.

    Mobile genetic elements and their contribution to the emergence of antimicrobial resistant Enterococcus faecalis and Enterococcus faecium.

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases . 16(6): 541-554. Number of citations: 206

    [doi:10.1111/j.1469-0691.2010.03226.x]

  • Freitas AR, Tedim AP, Novais C, Ruiz-Garbajosa P, Werner G, Laverde-Gomez JA, Cantón R, Peixe L, Baquero F, Coque TM.

    Global spread of the hyl(Efm) colonization-virulence gene in megaplasmids of the Enterococcus faecium CC17 polyclonal subcluster.

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 54(6): 2660-2665. Number of citations: 56

    [doi:10.1128/AAC.00134-10]

  • Cantón R, Ruiz-Garbajosa P, Chaves RL, Johnson AP.

    A potential role for daptomycin in enterococcal infections: what is the evidence?

    The Journal of antimicrobial chemotherapy . 65(6): 1126-1136. Number of citations: 65

    [doi:10.1093/jac/dkq087]

  • Lamas A, López-Herce J.

    Monitoring sedation in the critically ill child

    Anaesthesia . 65(5): 516-524. Number of citations: 10

    [doi:10.1111/j.1365-2044.2010.06263.x]

  • Turrientes MC, Baquero MR, Sánchez MB, Valdezate S, Escudero E, Berg G, Cantón R, Baquero F, Galán JC, Martínez JL.

    Polymorphic mutation frequencies of clinical and environmental Stenotrophomonas maltophilia populations.

    APPLIED AND ENVIRONMENTAL MICROBIOLOGY . 76(6): 1746-1758. Number of citations: 51

    [doi:10.1128/AEM.02817-09]

  • Miriagou V, Cornaglia G, Edelstein M, Galani I, Giske CG, Gniadkowski M, Malamou-Lada E, Martinez-Martinez L, Navarro F, Nordmann P, Peixe L, Pournaras S, Rossolini GM, Tsakris A, Vatopoulos A, Cantón R.

    Acquired carbapenemases in Gram-negative bacterial pathogens: detection and surveillance issues

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases . 16(2): 112-122. Number of citations: 241

    [doi:10.1111/j.1469-0691.2009.03116.x]

  • Novais A, Comas I, Baquero F, Cantón R, Coque TM, Moya A, González-Candelas F, Galán JC.

    Evolutionary trajectories of beta-lactamase CTX-M-1 cluster enzymes: predicting antibiotic resistance.

    PLOS PATHOGENS . 6(1): . Number of citations: 84

    [doi:10.1371/journal.ppat.1000735]

  • Bofarull AM, Royo AA, Fernández MH, Ortiz-Jaureguizar E, Morales J.

    Influence of continental history on the ecological specialization and macroevolutionary processes in the mammalian assemblage of South America: Differences between small and large mammals

    BMC EVOLUTIONARY BIOLOGY . 8: 97-97. Number of citations: 31

    [doi:10.1186/1471-2148-8-97]

  • Piñeiro Pérez R, Santiago García B, Fernández Llamazares CM, Baquero Artigao F, Noguera Julian A, Mellado Peña MJ, en representación de pTBred (Red Española de Estudio de Tuberculosis Pediátrica).

    [The challenge of administering anti-tuberculosis treatment in infants and pre-school children. pTBred Magistral Project].

    ANALES DE PEDIATRIA . : .

    [doi:10.1016/j.anpedi.2015.07.027]

  • De la Calle M, Baquero F, Rodriguez R, González M, Fernández A, Omeñaca F, Bartha JL.

    Successful treatment of intrauterine cytomegalovirus infection with an intraventricular cyst in a dichorionic diamniotic twin gestation using cytomegalovirus immunoglobulin.

    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians . : 1-4.

    [doi:10.1080/14767058.2017.1338259]

  • Braojos F, Fuentes I, Saugar JM, Martín O, López-Vélez R, Norman FF.

    Amebic abscess and sexual contact.

    JOURNAL OF TRAVEL MEDICINE . : .

    [doi:10.1093/jtm/taab089]

  • Zvezdanova ME, Arroyo MJ, Méndez G, Candela A, Mancera L, Rodríguez JG, Serra JL, Jiménez R, Lozano I, Castro C, López C, Muñoz P, Guinea J, Escribano P, Rodríguez-Sánchez B, ASPEIN group.

    Detection of azole resistance in Aspergillus fumigatus complex isolates using MALDI-TOF mass spectrometry.

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases . : .

    [doi:10.1016/j.cmi.2021.06.005]

  • Hernández-Aguado JJ, de La Fuente-Valero J, Ramírez Mena M, Ortega-Medina L, Vidart Aragón JA, Galán JC.

    Comparative pilot study about HPV test with partial genotyping in primary screening versus other strategies for cervical cancer population screening, CRYGEN 16/18 study.

    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA . : .

    [doi:10.1016/j.eimc.2021.07.010]

  • Escribano P, Gómez A, Reigadas E, Muñoz P, Guinea J.

    In vitro activity of olorofim against Aspergillus fumigatus sensu lato clinical isolates: activity is retained against isolates showing resistance to azoles and/or amphotericin B.

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases . : .

    [doi:10.1016/j.cmi.2022.05.013]

  • Mangas-Sánchez C, Garriga-García M, Serrano-Nieto MJ, Garcia-Romero R, Álvarez Beltrán M, Crehuá-Gaudiza E, Vicente-Santamaría S, Martínez-Costa C, Díaz-Martín JJ, Bousoño-García C, González-Jiménez D.

    Safety and efficacy of a new supplementation protocol in patients with cystic fibrosis and vitamin D deficiency.

    Anales De Pediatria . : .

    [doi:10.1016/j.anpede.2023.02.015]

  • Roca M, Masip E, Colombo C, Boon M, Hulst JM, Garriga M, de Koning BAE, Bulfamante A, de Boeck K, Ribes-Koninckx C, Calvo-Lerma J.

    Long-term evaluation of faecal calprotectin levels in a European cohort of children with cystic fibrosis.

    ARCHIVES OF DISEASE IN CHILDHOOD . : .

    [doi:10.1136/archdischild-2023-326221]