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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

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Only original articles, editorials, guidelines.

  • Freitas AR, Novais C, Correia R, Monteiro M, Coque TM, Peixe L.

    Non-susceptibility to tigecycline in enterococci from hospitalised patients, food products and community sources.

    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS . 38(2): 174-176. Number of citations: 18

    [doi:10.1016/j.ijantimicag.2011.04.014]

  • Baquero F.

    The 2010 Garrod Lecture: the dimensions of evolution in antibiotic resistance: ex unibus plurum et ex pluribus unum.

    The Journal of antimicrobial chemotherapy . 66(8): 1659-1672. Number of citations: 35

    [doi:10.1093/jac/dkr214]

  • Baquero F, Coque TM, de la Cruz F.

    Ecology and evolution as targets: the need for novel eco-evo drugs and strategies to fight antibiotic resistance.

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 55(8): 3649-3660. Number of citations: 129

    [doi:10.1128/AAC.00013-11]

  • Ledesma J, Vicente D, Pozo F, Cilla G, Castro SP, Fernández JS, Ruiz MP, Navarro JM, Galán JC, Fernández M, Reina J, Larrauri A, Cuevas MT, Casas I, Breña PP.

    Oseltamivir-resistant pandemic influenza a (H1N1) 2009 viruses in Spain

    JOURNAL OF CLINICAL VIROLOGY . 51(3): 205-208. Number of citations: 4

    [doi:10.1016/j.jcv.2011.04.008]

  • Delgado S, García P, Fernández L, Jiménez E, Rodríguez-Baños M, del Campo R, Rodríguez JM.

    Characterization of Staphylococcus aureus strains involved in human and bovine mastitis

    FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY . 62(2): 225-235. Number of citations: 50

    [doi:10.1111/j.1574-695X.2011.00806.x]

  • Andrade LN, Curiao T, Ferreira JC, Longo JM, Clímaco EC, Martinez R, Bellissimo-Rodrigues F, Basile-Filho A, Evaristo MA, Del Peloso PF, Ribeiro VB, Barth AL, Paula MC, Baquero F, Cantón R, Darini AL, Coque TM.

    Dissemination of blaKPC-2 by the spread of Klebsiella pneumoniae clonal complex 258 clones (ST258, ST11, ST437) and plasmids (IncFII, IncN, IncL/M) among Enterobacteriaceae species in Brazil.

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 55(7): 3579-3583. Number of citations: 145

    [doi:10.1128/AAC.01783-10]

  • Kechrid A, Pérez-Vázquez M, Smaoui H, Hariga D, Rodríguez-Baños M, Vindel A, Baquero F, Cantón R, Del Campo R.

    Molecular analysis of community-acquired methicillin-susceptible and resistant Staphylococcus aureus isolates recovered from bacteraemic and osteomyelitis infections in children from Tunisia.

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases . 17(7): 1020-1026. Number of citations: 31

    [doi:10.1111/j.1469-0691.2010.03367.x]

  • Read RC, Cornaglia G, Kahlmeter G.

    Professional challenges and opportunities in clinical microbiology and infectious diseases in Europe.

    LANCET INFECTIOUS DISEASES . 11(5): 408-415. Number of citations: 35

    [doi:10.1016/S1473-3099(10)70294-2]

  • Rodríguez-Avial I, Ramos B, Rios E.

    Clonal Spread of Levofloxacin-Resistant Streptococcus pneumoniae Invasive Isolates in Madrid, Spain, 2007 to 2009

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 55(5): 2469-2471. Number of citations: 23

    [doi:10.1128/AAC.01380-10]

  • Nordmann P, Picazo JJ, Mutters R.

    Comparative activity of carbapenem testing: the COMPACT study

    The Journal of antimicrobial chemotherapy . 66(5): 1070-1078. Number of citations: 30

    [doi:10.1093/jac/dkr056]

  • Ruiz SJ, Montealegre MC, Ruiz-Garbajosa P, Correa A, Briceño DF, Martinez E, Rosso F, Muñoz M, Quinn JP, Cantón R, Villegas MV.

    First Characterization of CTX-M-15-Producing Escherichia coli ST131 and ST405 Clones Causing Community-Onset Infections in South America

    JOURNAL OF CLINICAL MICROBIOLOGY . 49(5): 1993-1996. Number of citations: 39

    [doi:10.1128/JCM.00045-11]

  • Ledesma J, Pozo F, Pérez Ruiz M, Navarro JM, Piñeiro L, Montes M, Pérez Castro S, Suárez Fernández J, García Costa J, Fernández M, Galán JC, Cuevas MT, Casas I, Pérez Breña P.

    Substitutions in position 222 of haemagglutinin of pandemic influenza A (H1N1) 2009 viruses in Spain

    JOURNAL OF CLINICAL VIROLOGY . 51(1): 75-78. Number of citations: 26

    [doi:10.1016/j.jcv.2011.01.020]

  • Holguín A, Erazo K, Escobar G, de Mulder M, Yebra G, Martín L, Jovel LE, Castaneda L, Pérez E.

    Drug resistance prevalence in human immunodeficiency virus type 1 infected pediatric populations in Honduras and El Salvador during 1989-2009.

    PEDIATRIC INFECTIOUS DISEASE JOURNAL . 30(5): 82-87. Number of citations: 10

    [doi:10.1097/INF.0b013e3182117289]

  • Curiao T, Cantón R, Garcillán-Barcia MP, de la Cruz F, Baquero F, Coque TM.

    Association of composite IS26-sul3 elements with highly transmissible IncI1 plasmids in extended-spectrum-beta-lactamase-producing Escherichia coli clones from humans.

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 55(5): 2451-2457. Number of citations: 35

    [doi:10.1128/AAC.01448-10]

  • García-Castillo M, del Campo R, Baquero F, Morosini MI, Turrientes MC, Zamora J, Cantón R.

    Stationary biofilm growth normalizes mutation frequencies and mutant prevention concentrations in Pseudomonas aeruginosa from cystic fibrosis patients.

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases . 17(5): 704-711. Number of citations: 6

    [doi:10.1111/j.1469-0691.2010.03317.x]

  • Mouton JW, Ambrose PG, Canton R, Drusano GL, Harbarth S, MacGowan A, Theuretzbacher U, Turnidge J.

    Conserving antibiotics for the future: New ways to use old and new drugs from a pharmacokinetic and pharmacodynamic perspective

    DRUG RESISTANCE UPDATES . 14(2): 107-117. Number of citations: 144

    [doi:10.1016/j.drup.2011.02.005]

  • López M, Tenorio C, Del Campo R, Zarazaga M, Torres C.

    Characterization of the mechanisms of fluoroquinolone resistance in vancomycin-resistant enterococci of different origins.

    JOURNAL OF CHEMOTHERAPY . 23(2): 87-91. Number of citations: 15

    [doi:10.1179/joc.2011.23.2.87]

  • Gagliotti C, Balode A, Baquero F, Degener J, Grundmann H, Gür D, Jarlier V, Kahlmeter G, Monen J, Monnet DL, Rossolini GM, Suetens C, Weist K, Heuer O.

    Escherichia coli and Staphylococcus aureus: bad news and good news from the European Antimicrobial Resistance Surveillance Network (EARS-Net, formerly EARSS), 2002 to 2009.

    Eurosurveillance . 16(11): .