Neurodegenerative Diseases: pathogenic mechanisms
Search for publications
Only original articles, editorials, guidelines.
-
Pamplona FA, Ferreira J, Menezes de Lima O, Duarte FS, Bento AF, Forner S, Villarinho JG, Bellocchio L, Bellochio L, Wotjak CT, Lerner R, Monory K, Lutz B, Canetti C, Matias I, Calixto JB, Marsicano G, Guimarães MZ, Takahashi RN.
Anti-inflammatory lipoxin A(4) is an endogenous allosteric enhancer of CB1 cannabinoid receptor
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA . 109(51): 21134-21139. Number of citations: 128
-
Díaz-Alonso J, Guzmán M, Galve-Roperh I.
Endocannabinoids via CB1 receptors act as neurogenic niche cues during cortical development
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES . 367(1607, SI): 3229-3241. Number of citations: 56
-
Díaz-Alonso J, Aguado T, Wu CS, Palazuelos J, Hofmann C, Garcez P, Guillemot F, Lu HC, Lutz B, Guzmán M, Galve-Roperh I.
The CB1 Cannabinoid Receptor Drives Corticospinal Motor Neuron Differentiation through the Ctip2/Satb2 Transcriptional Regulation Axis
JOURNAL OF NEUROSCIENCE . 32(47): 16651-16665. Number of citations: 58
-
Caffarel MM, Andradas C, Pérez-Gómez E, Guzmán M, Sánchez C.
Cannabinoids: A new hope for breast cancer therapy?
CANCER TREATMENT REVIEWS . 38(7): 911-918. Number of citations: 69
-
Cardinal P, Bellocchio L, Clark S, Cannich A, Klugmann M, Lutz B, Marsicano G, Cota D.
Hypothalamic CB1 Cannabinoid Receptors Regulate Energy Balance in Mice
Endocrinology . 153(9): 4136-4143. Number of citations: 84
-
Velasco G, Sánchez C, Guzmán M.
Towards the use of cannabinoids as antitumour agents
NATURE REVIEWS CANCER . 12(6): 436-444. Number of citations: 228
-
Bénard G, Massa F, Puente N, Lourenço J, Bellocchio L, Soria-Gómez E, Matias I, Delamarre A, Metna-Laurent M, Cannich A, Hebert-Chatelain E, Mulle C, Ortega-Gutiérrez S, Martín-Fontecha M, Klugmann M, Guggenhuber S, Lutz B, Gertsch J, Chaouloff F, López-Rodríguez ML, Grandes P, Rossignol R, Marsicano G.
Mitochondrial CB1 receptors regulate neuronal energy metabolism
NATURE NEUROSCIENCE . 15(4): 558-564. Number of citations: 316
-
Bañez-Coronel M, Porta S, Kagerbauer B, Mateu-Huertas E, Pantano L, Ferrer I, Guzmán M, Estivill X, Martí E.
A Pathogenic Mechanism in Huntington's Disease Involves Small CAG-Repeated RNAs with Neurotoxic Activity
PLOS GENETICS . 8(2): . Number of citations: 126
-
Palazuelos J, Ortega Z, Díaz-Alonso J, Guzmán M, Galve-Roperh I.
CB2 Cannabinoid Receptors Promote Neural Progenitor Cell Proliferation via mTORC1 Signaling
JOURNAL OF BIOLOGICAL CHEMISTRY . 287(2): 1198-1209. Number of citations: 108
-
Lorente M, Torres S, Salazar M, Carracedo A, Hernández-Tiedra S, Rodríguez-Fornés F, García-Taboada E, Meléndez B, Mollejo M, Campos-Martín Y, Barcia JA, Guzmán M, Velasco G.
Stimulation of ALK by the growth factor midkine renders glioma cells resistant to autophagy-mediated cell death
Autophagy . 7(9): 1071-1073. Number of citations: 20
-
Fernández-Ruiz J, Moreno-Martet M, Rodríguez-Cueto C, Palomo-Garo C, Gómez-Cañas M, Valdeolivas S, Guaza C, Romero J, Guzmán M, Mechoulam R, Ramos JA.
Prospects for cannabinoid therapies in basal ganglia disorders
BRITISH JOURNAL OF PHARMACOLOGY . 163(7, SI): 1365-1378. Number of citations: 80
-
Vara D, Salazar M, Olea-Herrero N, Guzmán M, Velasco G, Díaz-Laviada I.
Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy
CELL DEATH AND DIFFERENTIATION . 18(7): 1099-1111. Number of citations: 187
-
Lorente M, Torres S, Salazar M, Carracedo A, Hernández-Tiedra S, Rodríguez-Fornés F, García-Taboada E, Meléndez B, Mollejo M, Campos-Martín Y, Lakatosh SA, Barcia J, Guzmán M, Velasco G.
Stimulation of the midkine/ALK axis renders glioma cells resistant to cannabinoid antitumoral action
CELL DEATH AND DIFFERENTIATION . 18(6): 959-973. Number of citations: 62
-
Andradas C, Caffarel MM, Pérez-Gómez E, Salazar M, Lorente M, Velasco G, Guzmán M, Sánchez C.
The orphan G protein-coupled receptor GPR55 promotes cancer cell proliferation via ERK
Oncogene . 30(2): 245-252. Number of citations: 134
-
Salazar M, Hernández-Tiedra S, Torres S, Lorente M, Guzmán M, Velasco G.
DETECTING AUTOPHAGY IN RESPONSE TO ER STRESS SIGNALS IN CANCER
METHOD ENZYMOL . 489: 297-317. Number of citations: 22
-
Torres S, Lorente M, Rodríguez-Fornés F, Hernández-Tiedra S, Salazar M, García-Taboada E, Barcia J, Guzmán M, Velasco G.
A Combined Preclinical Therapy of Cannabinoids and Temozolomide against Glioma
MOLECULAR CANCER THERAPEUTICS . 10(1): 90-103. Number of citations: 173
-
Blázquez C, Chiarlone A, Sagredo O, Aguado T, Pazos MR, Resel E, Palazuelos J, Julien B, Salazar M, Börner C, Benito C, Carrasco C, Diez-Zaera M, Paoletti P, Díaz-Hernández M, Ruiz C, Sendtner M, Lucas JJ, de Yébenes JG, Marsicano G, Monory K, Lutz B, Romero J, Alberch J, Ginés S, Kraus J, Fernández-Ruiz J, Galve-Roperh I, Guzmán M.
Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease
Brain . 134(1): 119-136. Number of citations: 135
-
Caffarel MM, Andradas C, Mira E, Pérez-Gómez E, Cerutti C, Moreno-Bueno G, Flores JM, García-Real I, Palacios J, Mañes S, Guzmán M, Sánchez C.
Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition
MOLECULAR CANCER . 9: 196-196. Number of citations: 105