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Neurodegenerative diseases: pathogenic mechanisms

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  • Sanchez D, Bajo-Grañeras R, Del Caño-Espinel M, Garcia-Centeno R, Garcia-Mateo N, Pascua-Maestro R, Ganfornina MD.

    Aging without Apolipoprotein D: Molecular and cellular modifications in the hippocampus and cortex

    EXPERIMENTAL GERONTOLOGY . 67: 19-47. Number of citations: 24

    [doi:10.1016/j.exger.2015.04.003]

  • Stern CA, Gazarini L, Vanvossen AC, Zuardi AW, Galve-Roperh I, Guimaraes FS, Takahashi RN, Bertoglio LJ.

    Delta(9)-Tetrahydrocannabinol alone and combined with cannabidiol mitigate fear memory through reconsolidation disruption

    EUROPEAN NEUROPSYCHOPHARMACOLOGY . 25(6): 958-965. Number of citations: 42

    [doi:10.1016/j.euroneuro.2015.02.001]

  • Abrams DI, Guzman M.

    Cannabis in Cancer Care

    CLINICAL PHARMACOLOGY & THERAPEUTICS . 97(6): 575-586. Number of citations: 111

    [doi:10.1002/cpt.108]

  • Pérez-Gómez E, Andradas C, Blasco-Benito S, Caffarel MM, García-Taboada E, Villa-Morales M, Moreno E, Hamann S, Martín-Villar E, Flores JM, Wenners A, Alkatout I, Klapper W, Röcken C, Bronsert P, Stickeler E, Staebler A, Bauer M, Arnold N, Soriano J, Pérez-Martínez M, Megías D, Moreno-Bueno G, Ortega-Gutiérrez S, Artola M, Vázquez-Villa H, Quintanilla M, Fernández-Piqueras J, Canela EI, McCormick PJ, Guzmán M, Sánchez C.

    Role of Cannabinoid Receptor CB2 in HER2 Pro-oncogenic Signaling in Breast Cancer

    JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE . 107(6): . Number of citations: 67

    [doi:10.1093/jnci/djv077]

  • Oddi D, Subashi E, Middei S, Bellocchio L, Lemaire-Mayo V, Guzmán M, Crusio WE, D'Amato FR, Pietropaolo S.

    Early Social Enrichment Rescues Adult Behavioral and Brain Abnormalities in a Mouse Model of Fragile X Syndrome

    NEUROPSYCHOPHARMACOLOGY . 40(5): 1113-1122. Number of citations: 62

    [doi:10.1038/npp.2014.291]

  • Garcez PP, Diaz-Alonso J, Crespo-Enriquez I, Castro D, Bell D, Guillemot F.

    Cenpj/CPAP regulates progenitor divisions and neuronal migration in the cerebral cortex downstream of Ascl1

    NATURE COMMUNICATIONS . 6: 6474-6474. Number of citations: 37

    [doi:10.1038/ncomms7474]

  • Cardinal P, Bellocchio L, Guzmán-Quevedo O, André C, Clark S, Elie M, Leste-Lasserre T, Gonzales D, Cannich A, Marsicano G, Cota D.

    Cannabinoid Type 1 (CB1) Receptors on Sim1-Expressing Neurons Regulate Energy Expenditure in Male Mice

    Endocrinology . 156(2): 411-418. Number of citations: 31

    [doi:10.1210/en.2014-1437]

  • Pietropaolo S, Bellocchio L, Ruiz-Calvo A, Cabanas M, Du Z, Guzmán M, Garret M, Cho YH.

    Chronic cannabinoid receptor stimulation selectively prevents motor impairments in a mouse model of Huntington's disease

    Neuropharmacology . 89: 368-374. Number of citations: 21

    [doi:10.1016/j.neuropharm.2014.07.021]

  • Velasco G, Sánchez C, Guzmán M.

    Endocannabinoids and Cancer.

    Handbook of experimental pharmacology . 231: 449-472.

    [doi:10.1007/978-3-319-20825-1_16]

  • Crespo-Sanjuán J, Calvo-Nieves MD, Aguirre-Gervás B, Herreros-Rodríguez J, Velayos-Jiménez B, Castro-Alija MJ, Muñoz-Moreno MF, Sánchez D, Zamora-González N, Bajo-Grañeras R, García-Centeno RM, Largo Cabrerizo ME, Bustamante MR, Garrote-Adrados JA.

    Early Detection of High Oxidative Activity in Patients With Adenomatous Intestinal Polyps and Colorectal Adenocarcinoma: Myeloperoxidase and Oxidized Low-Density Lipoprotein in Serum as New Markers of Oxidative Stress in Colorectal Cancer

    Labmedicine . 46(2): 123-135. Number of citations: 18

    [doi:10.1309/LMZJJU6BC86WUDHW]

  • Salazar M, Lorente M, García-Taboada E, Pérez Gómez E, Dávila D, Zúñiga-García P, María Flores J, Rodríguez A, Hegedus Z, Mosén-Ansorena D, Aransay AM, Hernández-Tiedra S, López-Valero I, Quintanilla M, Sánchez C, Iovanna JL, Dusetti N, Guzmán M, Francis SE, Carracedo A, Kiss-Toth E, Velasco G.

    Loss of Tribbles pseudokinase-3 promotes Akt-driven tumorigenesis via FOXO inactivation

    CELL DEATH AND DIFFERENTIATION . 22(1, SI): 131-144. Number of citations: 61

    [doi:10.1038/cdd.2014.133]

  • Vicario-de-la-Torre M, Benítez-del-Castillo JM, Vico E, Guzmán M, de-Las-Heras B, Herrero-Vanrell R, Molina-Martínez IT.

    Design and Characterization of an Ocular Topical Liposomal Preparation to Replenish the Lipids of the Tear Film

    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE . 55(12): 7839-7847. Number of citations: 38

    [doi:10.1167/iovs.14-14700]

  • Maccarrone M, Guzmán M, Mackie K, Doherty P, Harkany T.

    Programming of neural cells by (endo) cannabinoids: from physiological rules to emerging therapies

    NATURE REVIEWS NEUROSCIENCE . 15(12): 786-801. Number of citations: 180

    [doi:10.1038/nrn3846]

  • Soria-Gomez E, Bellocchio L, Marsicano G.

    New insights on food intake control by olfactory processes: The emerging role of the endocannabinoid system

    MOLECULAR AND CELLULAR ENDOCRINOLOGY . 397(1-2, SI): 59-66. Number of citations: 27

    [doi:10.1016/j.mce.2014.09.023]

  • Cardinal P, André C, Quarta C, Bellocchio L, Clark S, Elie M, Leste-Lasserre T, Maitre M, Gonzales D, Cannich A, Pagotto U, Marsicano G, Cota D.

    CB1 cannabinoid receptor in SF1-expressing neurons of the ventromedial hypothalamus determines metabolic responses to diet and leptin

    Molecular metabolism . 3(7): 705-716. Number of citations: 54

    [doi:10.1016/j.molmet.2014.07.004]

  • Guzmán M, Sabbione F, Gabelloni ML, Vanzulli S, Trevani AS, Giordano MN, Galletti JG.

    Restoring Conjunctival Tolerance by Topical Nuclear Factor-kappa B Inhibitors Reduces Preservative-Facilitated Allergic Conjunctivitis in Mice

    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE . 55(9): 6116-6126. Number of citations: 27

    [doi:10.1167/iovs.14-14075]

  • Moreno E, Andradas C, Medrano M, Caffarel MM, Pérez-Gómez E, Blasco-Benito S, Gómez-Cañas M, Pazos MR, Irving AJ, Lluís C, Canela EI, Fernández-Ruiz J, Guzmán M, McCormick PJ, Sánchez C.

    Targeting CB2-GPR55 Receptor Heteromers Modulates Cancer Cell Signaling

    JOURNAL OF BIOLOGICAL CHEMISTRY . 289(32): 21960-21972. Number of citations: 71

    [doi:10.1074/jbc.M114.561761]

  • Chiarlone A, Bellocchio L, Blázquez C, Resel E, Soria-Gómez E, Cannich A, Ferrero JJ, Sagredo O, Benito C, Romero J, Sánchez-Prieto J, Lutz B, Fernández-Ruiz J, Galve-Roperh I, Guzmán M.

    A restricted population of CB1 cannabinoid receptors with neuroprotective activity

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA . 111(22): 8257-8262. Number of citations: 109

    [doi:10.1073/pnas.1400988111]