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Biomarkers and Personalized Approach to Cancer Group (BioPAC)

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  • González I, Earl J, Fernández LJ, Sainz B, Pinto A, Monge R, Alcalá S, Castillejo A, Soto JL, Carrato A.

    A Label Free Disposable Device for Rapid Isolation of Rare Tumor Cells from Blood by Ultrasounds.

    MICROMACHINES . 9(3): . Number of citations: 13

    [doi:10.3390/mi9030129]

  • Djurec M, Graña O, Lee A, Troulé K, Espinet E, Cabras L, Navas C, Blasco MT, Martín-Díaz L, Burdiel M, Li J, Liu Z, Vallespinós M, Sanchez-Bueno F, Sprick MR, Trumpp A, Sainz B, Al-Shahrour F, Rabadan R, Guerra C, Barbacid M.

    Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors.

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA . 115(6): 1147-1156. Number of citations: 79

    [doi:10.1073/pnas.1717802115]

  • Valle S, Martin-Hijano L, Alcalá S, Alonso-Nocelo M, Sainz B.

    The Ever-Evolving Concept of the Cancer Stem Cell in Pancreatic Cancer.

    Cancers . 10(2): . Number of citations: 65

    [doi:10.3390/cancers10020033]

  • D'Errico G, Machado HL, Sainz B.

    A current perspective on cancer immune therapy: step-by-step approach to constructing the magic bullet.

    Clinical And Translational Medicine . 6(1): 3-3. Number of citations: 44

    [doi:10.1186/s40169-016-0130-5]

  • da Silva IL, Montero-Montero L, Martín-Villar E, Martin-Pérez J, Sainz B, Renart J, Toscano Simões R, Soares Veloso É, Salviano Teixeira C, de Oliveira MC, Ferreira E, Quintanilla M.

    Reduced expression of the murine HLA-G homolog Qa-2 is associated with malignancy, epithelial-mesenchymal transition and stemness in breast cancer cells.

    SCIENTIFIC REPORTS . 7(1): 6276-6276. Number of citations: 8

    [doi:10.1038/s41598-017-06528-x]

  • López-Gómez M, Casado E, Muñoz M, Alcalá S, Moreno-Rubio J, D'Errico G, Jiménez-Gordo AM, Salinas S, Sainz B.

    Current evidence for cancer stem cells in gastrointestinal tumors and future research perspectives.

    CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY . 107: 54-71. Number of citations: 3

    [doi:10.1016/j.critrevonc.2016.08.006]

  • Zagorac S, Alcala S, Fernandez Bayon G, Bou Kheir T, Schoenhals M, González-Neira A, Fernandez Fraga M, Aicher A, Heeschen C, Sainz B.

    DNMT1 Inhibition Reprograms Pancreatic Cancer Stem Cells via Upregulation of the miR-17-92 Cluster

    CANCER RESEARCH . 76(15): 4546-4558. Number of citations: 71

    [doi:10.1158/0008-5472.CAN-15-3268]

  • Sancho P, Alcala S, Usachov V, Hermann PC, Sainz B.

    The ever-changing landscape of pancreatic cancer stem cells.

    Pancreatology . 16(4): 489-496. Number of citations: 19

    [doi:10.1016/j.pan.2016.04.004]

  • Sainz B, Carron E, Vallespinós M, Machado HL.

    Cancer Stem Cells and Macrophages: Implications in Tumor Biology and Therapeutic Strategies

    MEDIATORS OF INFLAMMATION . 2016: 9012369-9012369. Number of citations: 66

    [doi:10.1155/2016/9012369]

  • Cioffi M, Vallespinos-Serrano M, Trabulo SM, Fernandez-Marcos PJ, Firment AN, Vazquez BN, Vieira CR, Mulero F, Camara JA, Cronin UP, Perez M, Soriano J, G Galvez B, Castells-Garcia A, Haage V, Raj D, Megias D, Hahn S, Serrano L, Moon A, Aicher A, Heeschen C.

    MiR-93 Controls Adiposity via Inhibition of Sirt7 and Tbx3

    CELL REPORTS . 12(10): 1594-1605. Number of citations: 79

    [doi:10.1016/j.celrep.2015.08.006]

  • Hohwieler M, Illing A, Hermann PC, Mayer T, Stockmann M, Perkhofer L, Eiseler T, Antony JS, Müller M, Renz S, Kuo CC, Lin Q, Sendler M, Breunig M, Kleiderman SM, Lechel A, Zenker M, Leichsenring M, Rosendahl J, Zenke M, Sainz B, Mayerle J, Costa IG, Seufferlein T, Kormann M, Wagner M, Liebau S, Kleger A.

    Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling.

    Gut . : .

    [doi:10.1136/gutjnl-2016-312423]

  • Martinelli P, Carrillo-de Santa Pau E, Cox T, Sainz B, Dusetti N, Greenhalf W, Rinaldi L, Costello E, Ghaneh P, Malats N, Büchler M, Pajic M, Biankin AV, Iovanna J, Neoptolemos J, Real FX.

    GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer.

    Gut . : .

    [doi:10.1136/gutjnl-2015-311256]

  • Rivas AS, Álvarez YE, Cordellat AB, Tarruella MM, Mata KM, de la Cámara MM, Del Mar Muñoz Sánchez M, Poves MZ, Zambrano CB, Gutierrez LC.

    SEOM clinical guidelines for cancer anorexia-cachexia syndrome (2023).

    CLINICAL & TRANSLATIONAL ONCOLOGY . : .

    [doi:10.1007/s12094-024-03502-8]

  • Villacampa A, Shamoon L, Valencia I, Morales C, Figueiras S, de la Cuesta F, Sánchez-Niño D, Díaz-Araya G, Sánchez-Pérez I, Lorenzo Ó, Sánchez-Ferrer CF, Peiró C.

    SARS-CoV-2 S Protein Reduces Cytoprotective Defenses and Promotes Human Endothelial Cell Senescence.

    AGING AND DISEASE . : .

    [doi:10.14336/AD.2024.0405]

  • Hughes BGM, Guminski A, Bowyer S, Migden MR, Schmults CD, Khushalani NI, Chang ALS, Grob JJ, Lewis KD, Ansstas G, Day F, Ladwa R, Stein BN, Muñoz Couselo E, Meier F, Hauschild A, Schadendorf D, Basset-Seguin N, Modi B, Dalac-Rat S, Dunn LA, Flatz L, Mortier L, Guégan S, Heinzerling LM, Mehnert JM, Trabelsi S, Soria-Rivas A, Stratigos AJ, Ulrich C, Wong DJ, Beylot-Barry M, Bossi P, Bugés Sánchez C, Chandra S, Robert C, Russell JS, Silk AW, Booth J, Yoo SY, Seebach F, Lowy I, Fury MG, Rischin D.

    A phase 2 open-label study of cemiplimab in patients with advanced cutaneous squamous cell carcinoma (EMPOWER-CSCC-1): Final long-term analysis of Groups 1, 2, and 3, and primary analysis of fixed-dose treatment Group 6.

    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY . : .

    [doi:10.1016/j.jaad.2024.06.108]

  • Márquez-Rodas I, Álvarez A, Arance A, Valduvieco I, Berciano-Guerrero MÁ, Delgado R, Soria A, López Campos F, Sánchez P, Luis Romero J, Martin-Liberal J, Lucas A, Díaz-Beveridge R, Conde-Moreno AJ, Álamo de la Gala MDC, García-Castaño A, José Prada P, González Cao M, Puertas E, Vidal J, Foro P, Aguado de la Rosa C, Corona JA, Cerezuela-Fuentes P, López P, Luna P, Aymar N, Puértolas T, Sanagustín P, Berrocal A.

    Encorafenib and binimetinib followed by radiotherapy for patients with BRAFV600-mutant melanoma and brain metastases (E-BRAIN/GEM1802 phase II study).

    Neuro-Oncology . : .

    [doi:10.1093/neuonc/noae116]

  • Rivera F, Longo F, Martín Richard M, Richart P, Alsina M, Carmona A, Custodio AB, Fernández Montes A, Gallego J, Fleitas Kanonnikoff T.

    SEOM-GEMCAD-TTD clinical guideline for the diagnosis and treatment of gastric cancer (2023).

    CLINICAL & TRANSLATIONAL ONCOLOGY . : .

    [doi:10.1007/s12094-024-03600-7]

  • Cerezuela-Fuentes P, Gonzalez-Cao M, Puertolas T, Manzano JL, Maldonado C, Yelamos O, Berciano-Guerrero MA, Martin-Liberal J, Muñoz-Couselo E, Espinosa E, Drozdowskyj A, Berrocal A, Soria A, Marquez-Rodas I, Martin-Algarra S, Quindos M, Puig S.

    Access to systemic treatment of non-melanoma skin cancer in Spain: a survey analysis.

    CLINICAL & TRANSLATIONAL ONCOLOGY . : .

    [doi:10.1007/s12094-024-03583-5]