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Biomarkers and Personalized Approach to Cancer Group (BioPAC)

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  • Cabezas-Sainz, Pablo, Pensado-Lopez, Alba, Sainz B Jr, Sanchez, Laura.

    Modeling Cancer Using Zebrafish Xenografts: Drawbacks for Mimicking the Human Microenvironment

    Cells . 9(9): . Number of citations: 22

    [doi:10.3390/cells9091978]

  • Cash, Timothy P., Alcala, Sonia, Rico-Ferreira MDR, Hernandez-Encinas, Elena, Garcia, Jennifer, Albarrán MI, Valle, Sandra, Muñoz J, Martinez-Gonzalez, Sonia, Blanco-Aparicio, Carmen, Pastor, Joaquin, Serrano, Manuel, Sainz B.

    Induction of Lysosome Membrane Permeabilization as a Therapeutic Strategy to Target Pancreatic Cancer Stem Cells

    Cancers . 12(7): . Number of citations: 6

    [doi:10.3390/cancers12071790]

  • Frappart, Pierre-Olivier, Walter, Karolin, Gout, Johann, Beutel, Alica K., Morawe, Mareen, Arnold, Frank, Breunig, Markus, Barth, Thomas F. E., Marienfeld, Ralf, Schulte, Lucas, Ettrich, Thomas, Hackert, Thilo, Svinarenko, Michael, Rösler R, Wiese, Sebastian, Wiese, Heike, Perkhofer, Lukas, Müller M, Lechel, Andre, Sainz B, Hermann, Patrick C., Seufferlein, Thomas, Kleger, Alexander.

    Pancreatic cancer-derived organoids - a disease modeling tool to predict drug response

    UNITED EUROPEAN GASTROENTEROLOGY JOURNAL . 8(5): 594-606. Number of citations: 45

    [doi:10.1177/2050640620905183]

  • Alcala, Sonia, Sancho, Patricia, Martinelli, Paola, Navarro, Diego, Pedrero, Coral, Martin-Hijano, Laura, Valle, Sandra, Earl, Julie, Rodriguez-Serrano, Macarena, Ruiz-Canas, Laura, Rojas, Katerin, Carrato, Alfredo, Garcia-Bermejo, Laura, Fernández-Moreno MÁ, Hermann, Patrick C., Sainz Jr, Bruno.

    ISG15 and ISGylation is required for pancreatic cancer stem cell mitophagy and metabolic plasticity

    NATURE COMMUNICATIONS . 11(1): 2682-2682. Number of citations: 45

    [doi:10.1038/s41467-020-16395-2]

  • Lerma, L., Muñoz AL, Garcia Utrilla, R., Sainz Jr, B., Lim, F., Tabares, E., Gomez-Sebastian, S..

    Partial complementation between the immediate early proteins ICP4 of herpes simplex virus type 1 and IE180 of pseudorabies virus

    VIRUS RESEARCH . 279: 197896-197896. Number of citations: 3

    [doi:10.1016/j.virusres.2020.197896]

  • Martin-Hijano, Laura, Sainz B.

    The Interactions Between Cancer Stem Cells and the Innate Interferon Signaling Pathway

    Frontiers in immunology . 11: 526-526. Number of citations: 26

    [doi:10.3389/fimmu.2020.00526]

  • Schulte, Lucas-Alexander, López-Gil JC, Sainz B, Hermann, Patrick C..

    The Cancer Stem Cell in Hepatocellular Carcinoma

    Cancers . 12(3): . Number of citations: 29

    [doi:10.3390/cancers12030684]

  • Pajuelo-Lozano, Natalia, Alcala, Sonia, Sainz B, Perona, Rosario, Sanchez-Perez, Isabel.

    Targeting MAD2 modulates stemness and in human Gastric Cancer cell lines

    THERANOSTICS . 10(21): 9601-9618. Number of citations: 24

    [doi:10.7150/thno.49270]

  • Rodriguez-Aznar E, Wiesmüller L, Sainz B, Hermann PC.

    EMT and Stemness-Key Players in Pancreatic Cancer Stem Cells.

    Cancers . 11(8): . Number of citations: 56

    [doi:10.3390/cancers11081136]

  • D'Errico G, Alonso-Nocelo M, Vallespinos M, Hermann PC, Alcalá S, García CP, Martin-Hijano L, Valle S, Earl J, Cassiano C, Lombardia L, Feliu J, Monti MC, Seufferlein T, García-Bermejo L, Martinelli P, Carrato A, Sainz B.

    Tumor-associated macrophage-secreted 14-3-3? signals via AXL to promote pancreatic cancer chemoresistance.

    Oncogene . 38(27): 5469-5485. Number of citations: 33

    [doi:10.1038/s41388-019-0803-9]

  • Walter K, Tiwary K, Trajkovic-Arsic M, Hidalgo-Sastre A, Dierichs L, Liffers ST, Gu J, Gout J, Schulte LA, Münch J, Seufferlein T, Sainz B, Siveke JT, Rodriguez-Aznar E, Hermann PC.

    MEK Inhibition Targets Cancer Stem Cells and Impedes Migration of Pancreatic Cancer Cells In Vitro and In Vivo .

    STEM CELLS INTERNATIONAL . 2019: 8475389-8475389. Number of citations: 8

    [doi:10.1155/2019/8475389]

  • Alcalá S, Martinelli P, Hermann PC, Heeschen C, Sainz B.

    The Anthrax Toxin Receptor 1 (ANTXR1) Is Enriched in Pancreatic Cancer Stem Cells Derived from Primary Tumor Cultures.

    STEM CELLS INTERNATIONAL . 2019: 1378639-1378639. Number of citations: 6

    [doi:10.1155/2019/1378639]

  • Blasco MT, Navas C, Martín-Serrano G, Graña-Castro O, Lechuga CG, Martín-Díaz L, Djurec M, Li J, Morales-Cacho L, Esteban-Burgos L, Perales-Patón J, Bousquet-Mur E, Castellano E, Jacob HKC, Cabras L, Musteanu M, Drosten M, Ortega S, Mulero F, Sainz B, Dusetti N, Iovanna J, Sánchez-Bueno F, Hidalgo M, Khiabanian H, Rabadán R, Al-Shahrour F, Guerra C, Barbacid M.

    Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF.

    Cancer Cell . 35(4): 573. Number of citations: 37

    [doi:10.1016/j.ccell.2019.03.002]

  • Alcalá S, Sainz B.

    The dark side of radiotherapy-induced cell death in cancer.

    EBioMedicine . 40: 7-8. Number of citations: 2

    [doi:10.1016/j.ebiom.2019.01.047]

  • Hermann PC, Sainz B.

    Pancreatic cancer stem cells: A state or an entity?

    Seminars in cancer biology . 53: 223-231. Number of citations: 43

    [doi:10.1016/j.semcancer.2018.08.007]

  • Friederich MW, Timal S, Powell CA, Dallabona C, Kurolap A, Palacios-Zambrano S, Bratkovic D, Derks TGJ, Bick D, Bouman K, Chatfield KC, Damouny-Naoum N, Dishop MK, Falik-Zaccai TC, Fares F, Fedida A, Ferrero I, Gallagher RC, Garesse R, Gilberti M, González C, Gowan K, Habib C, Halligan RK, Kalfon L, Knight K, Lefeber D, Mamblona L, Mandel H, Mory A, Ottoson J, Paperna T, Pruijn GJM, Rebelo-Guiomar PF, Saada A, Sainz B, Salvemini H, Schoots MH, Smeitink JA, Szukszto MJ, Ter Horst HJ, van den Brandt F, van Spronsen FJ, Veltman JA, Wartchow E, Wintjes LT, Zohar Y, Fernández-Moreno MA, Baris HN, Donnini C, Minczuk M, Rodenburg RJ, Van Hove JLK.

    Pathogenic variants in glutamyl-tRNA Gln amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorder.

    NATURE COMMUNICATIONS . 9(1): 4065-4065. Number of citations: 20

    [doi:10.1038/s41467-018-06250-w]

  • Zagorac, Sladjana, Garcia-Bermejo, Laura, Sainz, Bruno, Jr..

    The Epigenetic Landscape of Pancreatic Cancer Stem Cells

    Epigenomes . 2(2): . Number of citations: 5

    [doi:10.3390/epigenomes2020010]

  • Alguacil-Núñez C, Ferrer-Ortiz I, García-Verdú E, López-Pirez P, Llorente-Cortijo IM, Sainz B.

    Current perspectives on the crosstalk between lung cancer stem cells and cancer-associated fibroblasts.

    CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY . 125: 102-110. Number of citations: 17

    [doi:10.1016/j.critrevonc.2018.02.015]