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Biomarkers and Personalized Approach to Cancer Group (BioPAC)

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  • Delle Cave, Donatella, Rizzo, Riccardo, Sainz B Jr, Gigli, Giuseppe, del Mercato, Loretta L., Lonardo, Enza.

    The Revolutionary Roads to Study Cell-Cell Interactions in 3D In Vitro Pancreatic Cancer Models

    Cancers . 13(4): . Number of citations: 16

    [doi:10.3390/cancers13040930]

  • López-Gil JC, Martin-Hijano, Laura, Hermann, Patrick C., Sainz B Jr.

    The CXCL12 Crossroads in Cancer Stem Cells and Their Niche

    Cancers . 13(3): . Number of citations: 23

    [doi:10.3390/cancers13030469]

  • Alcala, Sonia, Mayoral-Varo, Victor, Ruiz-Canas, Laura, Lopez-Gil, Juan Carlos, Heeschen, Christopher, Martin-Perez, Jorge, Sainz B Jr.

    Targeting SRC Kinase Signaling in Pancreatic Cancer Stem Cells (vol 21, 7437, 2020)

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 21(23): .

    [doi:10.3390/ijms21239215]

  • Valle, Sandra, Alcala, Sonia, Martin-Hijano, Laura, Cabezas-Sainz, Pablo, Navarro, Diego, Munoz ER, Yuste, Lourdes, Tiwary, Kanishka, Walter, Karolin, Ruiz-Canas, Laura, Alonso-Nocelo, Marta, Rubiolo, Juan A., Gonzalez-Arnay, Emilio, Heeschen, Christopher, Garcia-Bermejo, Laura, Hermann, Patrick C., Sanchez, Laura, Sancho, Patricia, Fernandez-Moreno MA, Sainz B Jr.

    Exploiting oxidative phosphorylation to promote the stem and immunoevasive properties of pancreatic cancer stem cells

    NATURE COMMUNICATIONS . 11(1): 5265-5265. Number of citations: 55

    [doi:10.1038/s41467-020-18954-z]

  • Alcala, Sonia, Mayoral-Varo, Victor, Ruiz-Canas, Laura, Lopez-Gil, Juan Carlos, Heeschen, Christopher, Martin-Perez, Jorge, Sainz B Jr.

    Targeting SRC Kinase Signaling in Pancreatic Cancer Stem Cells

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 21(20): . Number of citations: 6

    [doi:10.3390/ijms21207437]

  • Cabezas-Sainz, Pablo, Pensado-Lopez, Alba, Sainz B Jr, Sanchez, Laura.

    Modeling Cancer Using Zebrafish Xenografts: Drawbacks for Mimicking the Human Microenvironment

    Cells . 9(9): . Number of citations: 22

    [doi:10.3390/cells9091978]

  • Cash, Timothy P., Alcala, Sonia, Rico-Ferreira MDR, Hernandez-Encinas, Elena, Garcia, Jennifer, Albarrán MI, Valle, Sandra, Muñoz J, Martinez-Gonzalez, Sonia, Blanco-Aparicio, Carmen, Pastor, Joaquin, Serrano, Manuel, Sainz B.

    Induction of Lysosome Membrane Permeabilization as a Therapeutic Strategy to Target Pancreatic Cancer Stem Cells

    Cancers . 12(7): . Number of citations: 6

    [doi:10.3390/cancers12071790]

  • Frappart, Pierre-Olivier, Walter, Karolin, Gout, Johann, Beutel, Alica K., Morawe, Mareen, Arnold, Frank, Breunig, Markus, Barth, Thomas F. E., Marienfeld, Ralf, Schulte, Lucas, Ettrich, Thomas, Hackert, Thilo, Svinarenko, Michael, Rösler R, Wiese, Sebastian, Wiese, Heike, Perkhofer, Lukas, Müller M, Lechel, Andre, Sainz B, Hermann, Patrick C., Seufferlein, Thomas, Kleger, Alexander.

    Pancreatic cancer-derived organoids - a disease modeling tool to predict drug response

    UNITED EUROPEAN GASTROENTEROLOGY JOURNAL . 8(5): 594-606. Number of citations: 45

    [doi:10.1177/2050640620905183]

  • Alcala, Sonia, Sancho, Patricia, Martinelli, Paola, Navarro, Diego, Pedrero, Coral, Martin-Hijano, Laura, Valle, Sandra, Earl, Julie, Rodriguez-Serrano, Macarena, Ruiz-Canas, Laura, Rojas, Katerin, Carrato, Alfredo, Garcia-Bermejo, Laura, Fernández-Moreno MÁ, Hermann, Patrick C., Sainz Jr, Bruno.

    ISG15 and ISGylation is required for pancreatic cancer stem cell mitophagy and metabolic plasticity

    NATURE COMMUNICATIONS . 11(1): 2682-2682. Number of citations: 45

    [doi:10.1038/s41467-020-16395-2]

  • Lerma, L., Muñoz AL, Garcia Utrilla, R., Sainz Jr, B., Lim, F., Tabares, E., Gomez-Sebastian, S..

    Partial complementation between the immediate early proteins ICP4 of herpes simplex virus type 1 and IE180 of pseudorabies virus

    VIRUS RESEARCH . 279: 197896-197896. Number of citations: 3

    [doi:10.1016/j.virusres.2020.197896]

  • Martin-Hijano, Laura, Sainz B.

    The Interactions Between Cancer Stem Cells and the Innate Interferon Signaling Pathway

    Frontiers in immunology . 11: 526-526. Number of citations: 26

    [doi:10.3389/fimmu.2020.00526]

  • Schulte, Lucas-Alexander, López-Gil JC, Sainz B, Hermann, Patrick C..

    The Cancer Stem Cell in Hepatocellular Carcinoma

    Cancers . 12(3): . Number of citations: 29

    [doi:10.3390/cancers12030684]

  • Pajuelo-Lozano, Natalia, Alcala, Sonia, Sainz B, Perona, Rosario, Sanchez-Perez, Isabel.

    Targeting MAD2 modulates stemness and in human Gastric Cancer cell lines

    THERANOSTICS . 10(21): 9601-9618. Number of citations: 24

    [doi:10.7150/thno.49270]

  • Rodriguez-Aznar E, Wiesmüller L, Sainz B, Hermann PC.

    EMT and Stemness-Key Players in Pancreatic Cancer Stem Cells.

    Cancers . 11(8): . Number of citations: 56

    [doi:10.3390/cancers11081136]

  • D'Errico G, Alonso-Nocelo M, Vallespinos M, Hermann PC, Alcalá S, García CP, Martin-Hijano L, Valle S, Earl J, Cassiano C, Lombardia L, Feliu J, Monti MC, Seufferlein T, García-Bermejo L, Martinelli P, Carrato A, Sainz B.

    Tumor-associated macrophage-secreted 14-3-3? signals via AXL to promote pancreatic cancer chemoresistance.

    Oncogene . 38(27): 5469-5485. Number of citations: 33

    [doi:10.1038/s41388-019-0803-9]

  • Walter K, Tiwary K, Trajkovic-Arsic M, Hidalgo-Sastre A, Dierichs L, Liffers ST, Gu J, Gout J, Schulte LA, Münch J, Seufferlein T, Sainz B, Siveke JT, Rodriguez-Aznar E, Hermann PC.

    MEK Inhibition Targets Cancer Stem Cells and Impedes Migration of Pancreatic Cancer Cells In Vitro and In Vivo .

    STEM CELLS INTERNATIONAL . 2019: 8475389-8475389. Number of citations: 8

    [doi:10.1155/2019/8475389]

  • Alcalá S, Martinelli P, Hermann PC, Heeschen C, Sainz B.

    The Anthrax Toxin Receptor 1 (ANTXR1) Is Enriched in Pancreatic Cancer Stem Cells Derived from Primary Tumor Cultures.

    STEM CELLS INTERNATIONAL . 2019: 1378639-1378639. Number of citations: 6

    [doi:10.1155/2019/1378639]

  • Blasco MT, Navas C, Martín-Serrano G, Graña-Castro O, Lechuga CG, Martín-Díaz L, Djurec M, Li J, Morales-Cacho L, Esteban-Burgos L, Perales-Patón J, Bousquet-Mur E, Castellano E, Jacob HKC, Cabras L, Musteanu M, Drosten M, Ortega S, Mulero F, Sainz B, Dusetti N, Iovanna J, Sánchez-Bueno F, Hidalgo M, Khiabanian H, Rabadán R, Al-Shahrour F, Guerra C, Barbacid M.

    Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF.

    Cancer Cell . 35(4): 573. Number of citations: 37

    [doi:10.1016/j.ccell.2019.03.002]