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Biomarkers and Personalized Approach to Cancer Group (BioPAC)

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  • Márquez-Rodas I, Álvarez A, Arance A, Valduvieco I, Berciano-Guerrero MÁ, Delgado R, Soria A, López Campos F, Sánchez P, Luis Romero J, Martin-Liberal J, Lucas A, Díaz-Beveridge R, Conde-Moreno AJ, Álamo de la Gala MDC, García-Castaño A, José Prada P, González Cao M, Puertas E, Vidal J, Foro P, Aguado de la Rosa C, Corona JA, Cerezuela-Fuentes P, López P, Luna P, Aymar N, Puértolas T, Sanagustín P, Berrocal A.

    Encorafenib and binimetinib followed by radiotherapy for patients with BRAFV600-mutant melanoma and brain metastases (E-BRAIN/GEM1802 phase II study).

    NEURO-ONCOLOGY . 26(11): 2074-2083. Number of citations: 16

    [doi:10.1093/neuonc/noae116]

  • Mondaza-Hernandez JL, Hindi N, Fernandez-Serra A, Ramos R, Gonzalez-Cámpora R, Gómez-Mateo MC, Martinez-Trufero J, Lavernia J, Lopez-Pousa A, Laínez N, Martinez-Garcia J, Valverde C, Vaz-Salgado MÁ, Garcia-Plaza G, Marin-Borrero I, Carrillo-Garcia J, Martin-Ruiz M, Romero P, Gutierrez A, López-Guerrero JA, Moura DS, Martin-Broto J.

    Exploratory analysis of immunomodulatory factors identifies L1CAM as a prognostic marker in alveolar soft-part sarcoma.

    Therapeutic Advances in Medical Oncology . 16: . Number of citations: 2

    [doi:10.1177/17588359241293951]

  • Rivera F, Longo F, Martín Richard M, Richart P, Alsina M, Carmona A, Custodio AB, Fernández Montes A, Gallego J, Fleitas Kanonnikoff T.

    SEOM-GEMCAD-TTD clinical guideline for the diagnosis and treatment of gastric cancer (2023).

    Clinical & Translational Oncology . 26(11): 2826-2840. Number of citations: 6

    [doi:10.1007/s12094-024-03600-7]

  • Rivas AS, Álvarez YE, Cordellat AB, Tarruella MM, Mata KM, de la Cámara MM, Del Mar Muñoz Sánchez M, Poves MZ, Zambrano CB, Gutierrez LC.

    SEOM clinical guidelines for cancer anorexia-cachexia syndrome (2023).

    Clinical & Translational Oncology . 26(11): 2866-2876. Number of citations: 17

    [doi:10.1007/s12094-024-03502-8]

  • Buchholz M, Lausser L, Schenk M, Earl J, Lawlor RT, Scarpa A, Sanjuanbenito A, Carrato A, Malats N, Tjaden C, Giese NA, Büchler M, Hackert T, Kestler HA, Gress TM.

    Combined analysis of a serum mRNA/miRNA marker signature and CA 19-9 for timely and accurate diagnosis of recurrence after resection of pancreatic ductal adenocarcinoma: A prospective multicenter cohort study.

    United European Gastroenterology Journal . : . Number of citations: 4

    [doi:10.1002/ueg2.12676]

  • Chung HC, Saada-Bouzid E, Longo F, Yanez E, Im SA, Castanon E, Desautels DN, Graham DM, Garcia-Corbacho J, Lopez J, Dutcus C, Okpara CE, Ghori R, Jin F, Groisberg R, Korakis I.

    Lenvatinib plus pembrolizumab for patients with previously treated, advanced, triple-negative breast cancer: Results from the triple-negative breast cancer cohort of the phase 2 LEAP-005 Study.

    CANCER . 130(19): 3278-3288. Number of citations: 11

    [doi:10.1002/cncr.35387]

  • Alcala S, Serralta San Martin G, Muñoz-Fernández de Legaria M, Moreno-Rubio J, Salinas S, López-Gil JC, Rojo López JA, Martínez Alegre J, Cortes Bandy DA, Zambrana F, Jiménez-Gordo AM, Casado E, López-Gómez M, Sainz B.

    Autofluorescent Cancer Stem Cells: Potential Biomarker to Predict Recurrence in Resected Colorectal Tumors.

    Cancer Research Communications . 4(10): 2575-2588.

    [doi:10.1158/2767-9764.CRC-24-0188]

  • Budillon A, Leone A, Passaro E, Silvestro L, Foschini F, Iannelli F, Roca MS, Macchini M, Bruzzese F, Garcia Bermejo ML, Rodriguez Garrote M, Tortora G, Milella M, Reni M, Fuchs C, Hewitt E, Kubiak C, Di Gennaro E, Giannarelli D, Avallone A.

    Randomized phase 2 study of valproic acid combined with simvastatin and gemcitabine/nab-paclitaxel-based regimens in untreated metastatic pancreatic adenocarcinoma patients: the VESPA trial study protocol.

    BMC CANCER . 24(1): 1167-1167. Number of citations: 9

    [doi:10.1186/s12885-024-12936-w]

  • Niedra, Helvijs, Peculis, Raitis, Saksis, Rihards, Mandrika, Ilona, Vilisova, Sofija, Nazarovs, Jurijs, Breiksa, Austra, Gerina, Aija, Earl, Julie, Ruz-Caracuel, Ignacio, Rosas, Marta Gabriela, Pukitis, Aldis, Senterjakova, Natalja, Rovite, Vita.

    Tumor and a-SMA-expressing stromal cells in pancreatic neuroendocrine tumors have a distinct RNA profile depending on tumor grade

    Molecular Oncology . : . Number of citations: 7

    [doi:10.1002/1878-0261.13727]

  • Mirasierra M, Fernández-Pérez A, Lizarbe B, Keiran N, Ruiz-Cañas L, Casarejos MJ, Cerdán S, Vendrell J, Fernández-Veledo S, Vallejo M.

    Alx3 deficiency disrupts energy homeostasis, alters body composition, and impairs hypothalamic regulation of food intake.

    CELLULAR AND MOLECULAR LIFE SCIENCES . 81(1): 343-343.

    [doi:10.1007/s00018-024-05384-z]

  • Albarrán V, Guerrero P, de Quevedo CG, González C, Chamorro J, Rosero DI, Moreno J, Calvo JC, de Aguado PP, Alía V, Sotoca P, Barrill AM, Román MS, Álvarez-Ballesteros P, Serrano JJ, Soria A, Olmedo ME, Saavedra C, Cortés A, Gómez A, Lage Y, Ruiz Á, Ferreiro MR, Longo F, Garrido P, Gajate P.

    Negative association of steroids with immunotherapy efficacy in a multi-tumor cohort: time and dose-dependent.

    CANCER IMMUNOLOGY IMMUNOTHERAPY . 73(10): 186-186. Number of citations: 26

    [doi:10.1007/s00262-024-03772-9]

  • Melones-Herrero J, Delgado-Aliseda P, Figueiras S, Velázquez-Gutiérrez J, Quiroga AG, Calés C, Sánchez-Pérez I.

    Trans-[Pt(amine)Cl(2)(PPh(3))] Complexes Target Mitochondria and Endoplasmic Reticulum in Gastric Cancer Cells.

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 25(14): . Number of citations: 8

    [doi:10.3390/ijms25147739]

  • Moreno-Cabrera JM, Feliubadaló L, Pineda M, Prada-Dacasa P, Ramos-Muntada M, Del Valle J, Brunet J, Gel B, Currás-Freixes M, Calsina B, Salazar-Hidalgo ME, Rodríguez-Balada M, Roig B, Fernández-Castillejo S, Durán Domínguez M, Arranz Ledo M, Infante Sanz M, Castillejo A, Dámaso E, Soto JL, de Miguel M, Hidalgo Calero B, Sánchez-Zapardiel JM, Ramon Y Cajal T, Lasa A, Gisbert-Beamud A, López-Novo A, Ruiz-Ponte C, Potrony M, Álvarez-Mora MI, Osorio A, Lorda-Sánchez I, Robledo M, Cascón A, Ruiz A, Spataro N, Hernan I, Borràs E, Moles-Fernández A, Earl J, Cadiñanos J, Sánchez-Heras AB, Bigas A, Capellá G, Lázaro C.

    SpadaHC: a database to improve the classification of variants in hereditary cancer genes in the Spanish population.

    Database-The Journal of Biological Databases and Curation . 2024: . Number of citations: 1

    [doi:10.1093/database/baae055]

  • Van Laethem JL, Borbath I, Prenen H, Geboes KP, Lambert A, Mitry E, Cassier PA, Blanc JF, Pilla L, Batlle JF, Garrote MR, Pazo-Cid RA, Gallego I, Smith KE, Ellmark P, Pico de Coaña Y, Ambarkhane SV, Macarulla T.

    Combining CD40 agonist mitazalimab with mFOLFIRINOX in previously untreated metastatic pancreatic ductal adenocarcinoma (OPTIMIZE-1): a single-arm, multicentre phase 1b/2 study.

    LANCET ONCOLOGY . 25(7): 853-864. Number of citations: 47

    [doi:10.1016/S1470-2045(24)00263-8]

  • Cerezuela-Fuentes P, Gonzalez-Cao M, Puertolas T, Manzano JL, Maldonado C, Yelamos O, Berciano-Guerrero MA, Martin-Liberal J, Muñoz-Couselo E, Espinosa E, Drozdowskyj A, Berrocal A, Soria A, Marquez-Rodas I, Martin-Algarra S, Quindos M, Puig S.

    Access to systemic treatment of non-melanoma skin cancer in Spain: a survey analysis.

    Clinical & Translational Oncology . : . Number of citations: 1

    [doi:10.1007/s12094-024-03583-5]

  • Juez LD, Priego P, Cuadrado M, Blázquez LA, Sánchez-Picot S, Gil P, Longo F, Galindo J, Fernández-Cebrián JM, Botella-Carretero JI.

    Impact of Neoadjuvant Treatment on Body Composition in Patients with Locally Advanced Gastric Cancer.

    Cancers . 16(13): . Number of citations: 11

    [doi:10.3390/cancers16132408]

  • Ibello E, Saracino F, Delle Cave D, Buonaiuto S, Amoroso F, Andolfi G, Corona M, Guardiola O, Colonna V, Sainz B Jr, Altucci L, De Cesare D, Cobellis G, Lonardo E, Patriarca EJ, D'Aniello C, Minchiotti G.

    Three-dimensional environment sensitizes pancreatic cancer cells to the anti-proliferative effect of budesonide by reprogramming energy metabolism.

    JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH . 43(1): 165-165. Number of citations: 8

    [doi:10.1186/s13046-024-03072-1]

  • Gately L, Mesía C, Sepúlveda JM, Del Barco S, Pineda E, Gironés R, Fuster J, Dumas M, Gill S, Navarro LM, Herrero A, Dowling A, de Las Peñas R, Vaz MA, Alonso M, Lwin Z, Harrup R, Peralta S, Long A, Perez-Segura P, Ahern E, Garate CO, Wong M, Campbell R, Cuff K, Jennens R, Gallego O, Underhill C, Martinez-Garcia M, Covela M, Cooper A, Brown S, Rosenthal M, Torres J, Collins IM, Gibbs P, Balana C.

    Exploring management and outcomes of elderly patients with glioblastoma using data from two randomised trials (GEINO1401/EX-TEM).

    JOURNAL OF NEURO-ONCOLOGY . 168(2): 299-306. Number of citations: 2

    [doi:10.1007/s11060-024-04668-5]