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Biomarkers and Personalized Approach to Cancer Group (BioPAC)

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  • Soler G, Grávalos C, Rivera F, Safont MJ, Virgili AC, Valladares-Ayerbes M, Ferreiro-Monteagudo R, Ortiz-Morales MJ, Polo-Marques E, Kornusova-Bersheva I, Soustre E, Yao W, Élez E.

    Predictive factors of efficacy for FTD/TPI plus bevacizumab in refractory metastatic colorectal cancer patients: a subanalysis of the Spanish cohort from the SUNLIGHT phase III trial.

    Clinical & Translational Oncology . 27(11): 4203-4213. Number of citations: 1

    [doi:10.1007/s12094-025-03907-z]

  • Van Laethem JL, Geboes K, Borbath I, Macarulla Mercade T, Lambert A, Cassier P, Prenen H, Mitry E, Blanc JF, Pilla L, Feliu J, Rodriguez Garrote M, Pazo-Cid RA, Gallego I, Smith KE, Nordbladh K, Jimenez DG, Ellmark P, Pico de Coaña Y, Ambarkhane SV, Beatty GL, O'Reilly EM.

    CD40 agonist mitazalimab with mFOLFIRINOX in untreated metastatic pancreatic cancer: Biomarkers associated with outcomes from OPTIMIZE-1

    Cell Reports Medicine . 6(10): 102407-102407. Number of citations: 5

    [doi:10.1016/j.xcrm.2025.102407]

  • Palmerini E, Meazza C, Tamburini A, Márquez-Vega C, Bisogno G, Fagioli F, Ferraresi V, Milano GM, Coccoli L, Rubio-San-Simón A, Gallego O, Llinares Riestra ME, Manzitti C, Mora J, Vaz-Salgado MÁ, Luksch R, Mata C, Pierini M, Carretta E, Cesari M, Paioli A, Marrari A, Scotlandi K, Serra M, Asaftei SD, Gambarotti M, Picci P, Ferrari S, Valverde C, Ibrahim T, Broto JM.

    Is There a Role for Mifamurtide in Nonmetastatic High-Grade Osteosarcoma? Results From the Italian Sarcoma Group (ISG/OS-2) and Spanish Sarcoma Group (GEIS-33) Trials

    JOURNAL OF CLINICAL ONCOLOGY . 43(28): 3113-3122. Number of citations: 9

    [doi:10.1200/JCO-25-00210]

  • Vaz-Salgado MA, Valverde-Morales C, Alvarez R, Asencio JM, Collado E, de Alava E, Diaz Beveridge R, Gómez-Mateo MC, Gracia Alegria I, Marquina G, Martin Broto J, Martínez-Trufero J, Narváez JA, Redondo A, Sebio A, Verges R, Viñals JM, García Del Muro X.

    Diagnosis and Therapy of Soft Tissue Sarcomas: Spanish Group for Research in Sarcomas (GEIS) Guidelines

    Cancers . 17(19): . Number of citations: 4

    [doi:10.3390/cancers17193158]

  • Abal-Sanisidro M, Palencia-Campos A, Ruiz-Cañas L, García-Fernández J, Cañada-García L, Batres-Ramos S, López-López R, Moreno R, Martín-Pastor M, Sainz B Jr, de la Fuente M.

    Biocompatible self-illuminating sphingomyelin nanosystems for photodynamic-based cancer therapy

    JOURNAL OF CONTROLLED RELEASE . 385: 113982-113982. Number of citations: 3

    [doi:10.1016/j.jconrel.2025.113982]

  • Avendaño-Ortiz J, Tribaldo A, Ballestero L, Gómez LA, Gracia I, Rodríguez JF, Ramírez NB, Bodoque-Villar R, Vaz-Salgado MÁ, Del Campo R, Redondo-Calvo FJ.

    Antimicrobial Activity of Natural Extracts Against Catheter-Colonizing Methicillin-Resistant Staphylococcus aureus Clinical Isolates

    Biomedicines . 13(9): . Number of citations: 1

    [doi:10.3390/biomedicines13092150]

  • Parejo-Alonso B, Barneda D, Trabulo SMD, Courtois S, Compte-Sancerni S, Zurkovic J, Ruiz-Cañas L, Zheng Q, Tang J, Gaida MM, Schmitz U, Irun P, Penin-Peyta L, Crusz SM, Jagušt P, Espiau-Romera P, Royo-García A, Gordo-Ortiz A, Yuneva M, Lin ML, Huang S, Yang MH, Lanas A, Sainz B Jr, Thiele C, Heeschen C, Sancho P.

    PPARd Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer

    CANCER RESEARCH . 85(17): 3275-3291. Number of citations: 5

    [doi:10.1158/0008-5472.CAN-24-3475]

  • Melones-Herrero J, Aguilar-Rico F, Matesanz AI, Calés C, Sánchez-Pérez I, Quiroga AG.

    Antiproliferative activity in breast cancer cells of PtL2: A steroid-thiosemicarbazone platinum(II) complex

    JOURNAL OF INORGANIC BIOCHEMISTRY . 270: 112923-112923. Number of citations: 4

    [doi:10.1016/j.jinorgbio.2025.112923]

  • Martelli V, Vidal J, Gibert J, Fernández-Rodríguez MC, Linares J, García-Alfonso P, Páez D, Alonso V, Gomez-España MA, Guix M, Santos C, Duran G, Élez E, Garcia-Carbonero R, Ferreiro R, Pineda E, Sastre J, Cano MT, Manzano JL, Losa F, Aranda E, Rivera F, Sibilio A, Toledo R, Tabernero J, Salazar R, Bellosillo B, Montagut C.

    Clinical validation of liquid biopsy-RECIST (LB-RECIST) in metastatic colorectal cancer (mCRC) patients: findings from the PLATFORM-B study

    ESMO Open . 10(9): 105760-105760. Number of citations: 6

    [doi:10.1016/j.esmoop.2025.105760]

  • Panaitescu-Damian A, Gürcinar I, Stoica V, Paiella S, Hollenbach M, Regel I, Swibold D, Capurso G, Carrato A, Michl P, Arnes L.

    Addressing Pancreatic Exocrine Insufficiency and the Impact of Pancreatic Enzyme Replacement Therapy Shortages in Europe

    United European Gastroenterology Journal . 13(10): 2090-2092. Number of citations: 2

    [doi:10.1002/ueg2.70113]

  • Cave DD, Di Domenico A, Fantuz M, Ciotola M, Mangini M, Buonaiuto S, Corrado B, Corona M, Saracino F, Andolfi G, Di Biase I, Cucciardi A, Carrer A, Sainz B Jr, Pirozzi T, Re DL, Colonna V, Minchiotti G, De Luca AC, Lonardo E.

    TGF-ß1-mediated downregulation of L1CAM in pancreatic ductal adenocarcinoma drives upregulation of collagen 17A1 and MMP2, facilitating tumor invasiveness and metastasis

    Cell Death & Disease . 16(1): 592-592. Number of citations: 1

    [doi:10.1038/s41419-025-07859-8]

  • Earl J, Kataki A, Canzian F, Costello E, Campa D, Greenhalf W.

    Targeting pancreatic cancer screening by identification of pathogenic variants of BRCA2/ BRCA1 in healthy individuals who have no known family history of pancreatic cancer: The arguments for and against

    SEMINARS IN CANCER BIOLOGY . 113: 1-8.

    [doi:10.1016/j.semcancer.2025.05.001]

  • López-López C, de Castro EM, Montes AF, Orozco EJ, Peraita SL, Vera R, Cerdá P, Calvo M, Paredes BG, de Mena ML, La Casta A, Gallego J, Adeva J, Cano JMC, Ruiz-Casado A, Vidal-Tocino R, García-García T, Pazo-Cid R, Garrote MR, Sastre J.

    Real-world management and outcomes of patients with hepatocellular carcinoma treated with systemic therapy in Spain: a patient cohort from the RETUD gastrointestinal registry

    Clinical & Translational Oncology . 28(2): 589-600. Number of citations: 2

    [doi:10.1007/s12094-025-04010-z]

  • He J, Alhamwe BA, Sabroso S, Carrato A, Hidalgo M, Molero X, Iglesias M, Perea J, Farré A, Tardón A, Dominguez-Muñoz E, Barberà V, Muñoz-Bellvís L, Löhr M, Greenhalf W, O'Rorke M, Gress T, Crnogorac-Jurcevic T, Gayà A, Langtry A, Kleeff J, Lawlor R, Real FX, Renz H, Malats N.

    Low type-2 immune effectors modulate atopic diseases' protective role in pancreatic cancer risk

    INTERNATIONAL JOURNAL OF CANCER . 157(3): 468-479. Number of citations: 2

    [doi:10.1002/ijc.35397]

  • Alsina M, Villacampa G, de Andrea C, Vivancos A, Ponz-Sarvise M, Arrazubi V, Jimenez-Fonseca P, Diez M, Sanz-Garcia E, Martínez E, Guardeño R, Calvo M, Bugés C, Longo F, Navarro V, García-Galea E, Gros A, Ochoa MC, Lopez-Janeiro A, Sanchez-Gregorio S, Herrero C, Labiano I, Vila-Casadesús M, López D, Alexandru R, Muñoz S, Tabernero J, Melero I.

    A Phase II Study of Perioperative Avelumab plus Chemotherapy for Patients with Resectable Gastric Cancer or Gastroesophageal Junction Cancer - The MONEO Study

    CLINICAL CANCER RESEARCH . 31(14): 2890-2898. Number of citations: 4

    [doi:10.1158/1078-0432.CCR-25-0369]

  • Villacampa A, Shamoon L, Valencia I, Morales C, Figueiras S, de la Cuesta F, Sánchez-Niño D, Díaz-Araya G, Sánchez-Pérez I, Lorenzo Ó, Sánchez-Ferrer CF, Peiró C.

    SARS-CoV-2 S Protein Reduces Cytoprotective Defenses and Promotes Human Endothelial Cell Senescence

    Aging and Disease . 16(3): 1626-1638. Number of citations: 10

    [doi:10.14336/AD.2024.0405]

  • Raposeiras-Roubin S, Amat-Santos IJ, Rossello X, González Ferreiro R, González Bermúdez I, Lopez Otero D, Nombela-Franco L, Gheorghe L, Diez JL, Baladrón Zorita C, Baz JA, Muñoz García AJ, Vilalta V, Ojeda-Pineda S, de la Torre Hernández JM, Cordoba Soriano JG, Regueiro A, Bordes Siscar P, Salgado Fernández J, Garcia Del Blanco B, Martín-Reyes R, Romaguera R, Moris C, García Blas S, Franco-Peláez JA, Cruz-González I, Arzamendi D, Romero Rodríguez N, Díez-Del Hoyo F, Camacho Freire S, Bosa Ojeda F, Astorga Burgo JC, Molina Navarro E, Caballero Borrego J, Ruiz Quevedo V, Sánchez-Recalde Á, Peral Disdier V, Alegría-Barrero E, Torres-Llergo J, Feltes G, Fernández Díaz JA, Cuellas C, Jiménez Britez G, Sánchez-Rubio Lezcano J, Barreiro-Pardal C, Núñez-Gil I, Abu-Assi E, Iñiguez-Romo A, Fuster V, Ibáñez B.

    Dapagliflozin in Patients Undergoing Transcatheter Aortic-Valve Implantation

    NEW ENGLAND JOURNAL OF MEDICINE . 392(14): 1396-1405. Number of citations: 95

    [doi:10.1056/NEJMoa2500366]

  • Macarulla, T., Munoz, A., de Castro, E. Martinez, Castillo, A., Cano, M. T., Castet, F., Vidal, R., Ferrandez, A., Ghanem, I., Ales, I., Vera, R., Lobo, M., Adeva, J., Melian, M., Gallego, I., Laquente, B., Montes, A. Fernandez, Peinado, P., Paredes, B. Garcia, Pazo, R., Escobar, I. Garcia, de Mena, I. Ruiz, Carrato, A., Aranda, E..

    Real-world management and outcome of patients with pancreatic adenocarcinoma. Results of the Spanish RETUD gastrointestinal registry

    ESMO Real World Data and Digital Oncology . 7: 100116-100116. Number of citations: 2

    [doi:10.1016/j.esmorw.2025.100116]