At IRYCIS 6 Priority Research Areas are established, each one coordinated by 2 directors, with a basic mission to: i) ensure the achievement of the objectives set for their area overall; ii) guarantee communication and collaboration between the different research groups; iii) guide the emerging groups and the associate clinical researchers to achieve their progressive integration into the consolidated group level.

Chronic Pathologies and Surgery Research

Groups dedicated to different fields of biomedical research come together in Area 5 to address a broad spectrum of diseases with a high population impact and prevalence, increasingly due to sedentary lifestyles and population ageing; complex aspects of the disease, which cannot be characterised independently as they concur on most occasions in the same type of patient throughout the progression of the disease. All groups have a common denominator: the generation of clinical and translational projects with patient-centred objectives. In area 5, research is conducted on the physiopathology of cardiovascular, pneumological, multisystemic diseases, endocrine and metabolic disorders and digestive surgery.

Leaders

  • Dr. Federico Soria Gálvez

    Dr. Federico Soria Gálvez

    Chief of Experimental Surgery Department, Hospital Universitario Ramón y Cajal (Madrid). PhD in Translational Research (UEX, January 2023, Excellent Cum Laude). Research Lecturer at the University of Alcalá (Department of Surgery, Medical and Social Sciences) since 2023. Coordinator of the Endoscopic Surgery Unit (Research and Training) at the Fundación Centro de Cirugía de Mínima Invasión Jesús Usón (Cáceres, 1996-2022). President of the Animal Ethics Committee of the Ramón y Cajal University Hospital. Head of the Research Group "Surgical applications of drug delivery systems" of the IRYCIS.

    RESEARCH: 131 scientific articles in journals indexed with Impact factor; editor of 3 books on minimally invasive surgery; 8 chapters in books. Doctoral theses directed 6 (2013-2024), Master's theses directed 15; Principal investigator 20 national competitive projects; Collaborator in 18 national competitive projects; PI in 7 non-competitive projects with companies; Lecturer in more than 160 minimally invasive surgery activities; 5 medical device patents (national/European/international). Researcher in 3 European projects; Chairman of the European network ENIUS (European network of multidisciplinary Research to improve urinary stents. CA16217) 2017-2022 (European Cooperation in Science & Technology. Horizon Europe).

    Contact: federico.soria(ELIMINAR)@salud.madrid.org

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    Dr. Federico Soria Gálvez

    Head of Experimental Surgery Department

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  • Dr. Rosa Martín Mateos

    Dr. Rosa Martín Mateos

    Graduated in Medicine from the University of Alcalá in 2007 (extraordinary award) and specialized in Gastroenterology after completing her residency at the Ramón y Cajal Hospital in Madrid. In 2015, she earned a PhD in Medicine (Alcalá University), and complete a postdoctoral stay at Mayo Clinic (USA) in 2017. There, she led a basic science project investigating epigenetic modifications in liver fibrosis.

    Throughout her career, she has been awarded several research grants and distinctions, including the Juan Rodés Grant from the Spanish Association for the Study of the Liver (AEEH), the "Impulso" Grants, the Hepamad Group Research Award, and the Meda Grant in Gastroenterology. She has participated in numerous competitive projects funded by the Instituto de Salud Carlos III, contributing to both clinical and translational research. Additionally, she has complemented her academic training with master's degrees in Hepatology (Autonomous University of Madrid, 2015), Research Methodology (Autonomous University of Barcelona, 2014-2017), and Liver Transplantation (University of Seville, 2022-2023).

    In clinical practice, she has specialized in the diagnosis and comprehensive management of complex liver diseases, particularly those of alcoholic and metabolic origin, as well as liver transplantation. She is the first or co-author of over 60 scientific publications, including national consensus documents and clinical practice guidelines. She also serves as a reviewer for high-impact journals in her specialty and has been appointed as a Board Member of the AEEH since 2021 (2021-2025).

    Contact: rosam.martinma(ELIMINAR)@salud.madrid.org

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    Dr. Rosa Martín Mateos

    Digestive physician

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  • Martín Fabregate Fuente

    Martín Fabregate Fuente

    I am an Industrial Engineer from the Polytechnic University of Madrid. Since 2003, I have developed my professional career in the field of biomedical research, linked to the Ramón y Cajal University Hospital and the IRYCIS. I am currently Coordinator of the Research Support Unit of the Internal Medicine Service and researcher of the Multisystemic Diseases Group (area 5).

    Throughout my career I have participated in nearly 20 projects with competitive funding and more than 60 studies and clinical trials, both independently and in collaboration with companies in the pharmaceutical, technological and agri-food sectors. My experience in R&D&I management, research methodology and data science applied to the biomedical field have allowed me to contribute significantly to the design, execution and strategic planning of multidisciplinary projects aimed at improving healthcare and the quality of life of patients. In addition, I have experience as a teacher and pre- and postgraduate tutor, and evaluator in competitive calls for healthcare research and innovation.

    My scientific production includes more than 25 publications in indexed journals and 100 communications at national and international conferences. These works have allowed me to contribute to the advancement of clinical and translational research in areas as diverse as cardiovascular, autoimmune, rare or infectious diseases, as well as in the surgical field of vascular, neurological and spinal pathology.

    At IRYCIS, I am part of the Gender Equality Commission, collaborating in the promotion of the values ​​of respect, diversity, inclusion and equity in biomedical research. I also collaborate with the Innovation Unit, supporting the development of initiatives with potential for technological transfer and practical application of scientific results.

    Contact: martin.fabregate(ELIMINAR)@salud.madrid.org

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    Martín Fabregate Fuente

    Coordinator of the Research Support Unit, Internal Medicine Department

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Groups