Surgical applications of drug delivery systems

The current research group is a multidisciplinary team that allows it to address different areas of interest focused on experimental and translational surgery. The research group is focused on the development of biodegradable drug-eluting devices through polymeric matrices, which allow local drug instillation, allowing greater precision and reduction in the dose of the active ingredient. Another important research activity is focused on the development of cardiac devices, mainly on the design of a definitive artificial implantable ventricle. The group's activity is focused on the research projects they are implementing in these two research activities.

Group leader

Federico Soria Gálvez

Collaborating Staff

  • Jorge Rodríguez-Roda Stuart
  • Javier Miguelena Hycka
  • Irene María Pelayo Delgado
  • Gonzalo Mezquita Gómez
  • Carolina Berenice Torres Terreros
  • Rafael Muñoz Pérez
  • Miren Martín García
  • Luis Gajate Martín
  • Beatriz Barrocal López
  • Mercedes Liliana Castro Pinto
  • Mariangélica Chiquinquira González Aranguren
Imagen equipo

Group leader

Federico Soria Gálvez

Collaborating Staff

  • Jorge Rodríguez-Roda Stuart
  • Javier Miguelena Hycka
  • Irene María Pelayo Delgado
  • Gonzalo Mezquita Gómez
  • Carolina Berenice Torres Terreros
  • Rafael Muñoz Pérez
  • Miren Martín García
  • Luis Gajate Martín
  • Beatriz Barrocal López
  • Mercedes Liliana Castro Pinto
  • Mariangélica Chiquinquira González Aranguren

Strategic objectives 

  • To develop a biodegradable polymeric matrix capable of controlled and programmed topical drug release.
  • To advance the design of novel biodegradable ureteral stents with antireflux capabilities.
  • To develop a new questionnaire for assessing symptoms associated with ureteral catheters in urological patients.
  • To identify factors related to biofilm formation on double-J ureteral catheters and their relationship with bacteriuria and urinary tract infection in patients.
  • To develop new intracavitary instillation systems for the adjuvant treatment of upper urinary tract urothelial tumors. Coated biodegradable ureteral stents that release different chemotherapy cycles.
  • To evaluate new approaches using gynecological interventional ultrasound.
  • To evaluate new intracardiac implantable devices for the treatment of advanced heart failure.

Research lines

  • Evaluation and development of biodegradable ureteral stents.
  • Evaluation and development of drug-eluting ureteral stents.
  • Evaluation and development of cardiac devices.
  • Research into interventional ultrasound techniques in gynecology.

Location

Experimental Surgery Department

-3ª floor right

Ramón y Cajal University Hospital

+34 91 336 84 47

federico.soria@salud.madrid.org

Keywords

experimental surgery, endourology, ureteral stents, drug-eluting stents, biodegradable stents, permanently implantable artificial ventricle, interventional ultrasound, upper urinary tract urothelial carcinoma