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Aptamers

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  • Martins VT, Duarte MC, Lage DP, Costa LE, Carvalho AM, Mendes TA, Roatt BM, Menezes-Souza D, Soto M, Coelho EA.

    A recombinant chimeric protein composed of human and mice-specific CD4(+) and CD8(+) T-cell epitopes protects against visceral leishmaniasis.

    PARASITE IMMUNOLOGY . 39(1): . Number of citations: 30

    [doi:10.1111/pim.12359]

  • González VM, Martín ME, Fernández G, García-Sacristán A.

    Use of Aptamers as Diagnostics Tools and Antiviral Agents for Human Viruses.

    PHARMACEUTICALS . 9(4): . Number of citations: 45

    [doi:10.3390/ph9040078]

  • Iborra S, Martínez-López M, Cueto FJ, Conde-Garrosa R, Del Fresno C, Izquierdo HM, Abram CL, Mori D, Campos-Martín Y, Reguera RM, Kemp B, Yamasaki S, Robinson MJ, Soto M, Lowell CA, Sancho D.

    Leishmania Uses Mincle to Target an Inhibitory ITAM Signaling Pathway in Dendritic Cells that Dampens Adaptive Immunity to Infection

    Immunity . 45(4): 788-801. Number of citations: 58

    [doi:10.1016/j.immuni.2016.09.012]

  • Genes CM, de Lucio H, González VM, Sánchez-Murcia PA, Rico E, Gago F, Fasel N, Jiménez-Ruiz A.

    A functional BH3 domain in an aquaporin from Leishmania infantum.

    Cell death discovery . 2: 16043-16043.

    [doi:10.1038/cddiscovery.2016.43]

  • Duarte MC, Tavares GS, Valadares DG, Lage DP, Ribeiro TG, Lage LM, Rodrigues MR, Faraco AA, Soto M, da Silva ES, Chávez Fumagalli MA, Tavares CA, Leite JP, Oliveira JS, Castilho RO, Coelho EA.

    Antileishmanial activity and mechanism of action from a purified fraction of Zingiber officinalis Roscoe against Leishmania amazonensis

    EXPERIMENTAL PARASITOLOGY . 166: 21-28. Number of citations: 18

    [doi:10.1016/j.exppara.2016.03.026]

  • Duarte MC, Lage DP, Martins VT, Chávez-Fumagalli MA, Roatt BM, Menezes-Souza D, Goulart LR, Soto M, Tavares CA, Coelho EA.

    Recent updates and perspectives on approaches for the development of vaccines against visceral leishmaniasis

    REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL . 49(4): 398-407. Number of citations: 36

    [doi:10.1590/0037-8682-0120-2016]

  • Gutiérrez C, Serrano-Villar S, Madrid-Elena N, Pérez-Elías MJ, Martín ME, Barbas C, Ruipérez J, Muñoz E, Muñoz-Fernández MA, Castor T, Moreno S.

    Bryostatin-1 for latent virus reactivation in HIV-infected patients on antiretroviral therapy.

    AIDS . 30(9): 1385-1392. Number of citations: 111

    [doi:10.1097/QAD.0000000000001064]

  • Rodriguez P, Pérez-Morgado MI, Gonzalez VM, Martín ME, Nieto A.

    Inhibition of Influenza Virus Replication by DNA Aptamers Targeting a Cellular Component of Translation Initiation.

    MOLECULAR THERAPY-NUCLEIC ACIDS . 5: . Number of citations: 6

    [doi:10.1038/mtna.2016.20]

  • Lage DP, Martins VT, Duarte MC, Costa LE, Garde E, Dimer LM, Kursancew AC, Chávez-Fumagalli MA, de Magalhães-Soares DF, Menezes-Souza D, Roatt BM, Machado-de-Ávila RA, Soto M, Tavares CA, Coelho EA.

    A new Leishmania-specific hypothetical protein and its non-described specific B cell conformational epitope applied in the serodiagnosis of canine visceral leishmaniasis

    PARASITOLOGY RESEARCH . 115(4): 1649-1658. Number of citations: 24

    [doi:10.1007/s00436-016-4904-x]

  • Martins VT, Lage DP, Duarte MC, Costa LE, Garde E, Rodrigues MR, Chávez-Fumagalli MA, Menezes-Souza D, Roatt BM, Tavares CA, Soto M, Coelho EA.

    A new Leishmania-specific hypothetical protein, LiHyT, used as a vaccine antigen against visceral leishmaniasis

    ACTA TROPICA . 154: 73-81. Number of citations: 16

    [doi:10.1016/j.actatropica.2015.11.006]

  • Coelho EA, Costa LE, Lage DP, Martins VT, Garde E, de Jesus Pereira NC, Lopes EG, Borges LF, Duarte MC, Menezes-Souza D, de Magalhães-Soares DF, Chávez-Fumagalli MA, Soto M, Tavares CA.

    Evaluation of two recombinant Leishmania proteins identified by an immunoproteomic approach as tools for the serodiagnosis of canine visceral and human tegumentary leishmaniasis

    VETERINARY PARASITOLOGY . 215: 63-71. Number of citations: 24

    [doi:10.1016/j.vetpar.2015.11.006]

  • García-Recio EM, Pinto-Díez C, Pérez-Morgado MI, García-Hernández M, Fernández G, Martín ME, González VM.

    Characterization of MNK1b DNA Aptamers That Inhibit Proliferation in MDA-MB231 Breast Cancer Cells.

    MOLECULAR THERAPY-NUCLEIC ACIDS . 5: . Number of citations: 24

    [doi:10.1038/mtna.2015.50]

  • Lage PS, Chávez-Fumagalli MA, Mesquita JT, Mata LM, Fernandes SO, Cardoso VN, Soto M, Tavares CA, Leite JP, Tempone AG, Coelho EA.

    Antileishmanial activity and evaluation of the mechanism of action of strychnobiflavone flavonoid isolated from Strychnos pseudoquina against Leishmania infantum

    PARASITOLOGY RESEARCH . 114(12): 4625-4635. Number of citations: 24

    [doi:10.1007/s00436-015-4708-4]

  • Lage DP, Martins VT, Duarte MC, Garde E, Chávez-Fumagalli MA, Menezes-Souza D, Roatt BM, Tavares CA, Soto M, Coelho EA.

    Prophylactic properties of a Leishmania-specific hypothetical protein in a murine model of visceral leishmaniasis

    PARASITE IMMUNOLOGY . 37(12): 646-656. Number of citations: 29

    [doi:10.1111/pim.12287]

  • Perianes-Cachero A, Canelles S, Aguado-Llera D, Frago LM, Toledo-Lobo MV, Carrera I, Cacabelos R, Chowen JA, Argente J, Arilla-Ferreiro E, Barrios V.

    Reduction in A beta-induced cell death in the hippocampus of 17 beta-estradiol-treated female rats is associated with an increase in IGF-I signaling and somatostatinergic tone

    JOURNAL OF NEUROCHEMISTRY . 135(6): 1257-1271. Number of citations: 8

    [doi:10.1111/jnc.13381]

  • Duarte MC, Pimenta DC, Menezes-Souza D, Magalhães RD, Diniz JL, Costa LE, Chávez-Fumagalli MA, Lage PS, Bartholomeu DC, Alves MJ, Fernandes AP, Soto M, Tavares CA, Gonçalves DU, Rocha MO, Coelho EA.

    Proteins Selected in Leishmania (Viannia) braziliensis by an Immunoproteomic Approach with Potential Serodiagnosis Applications for Tegumentary Leishmaniasis

    CLINICAL AND VACCINE IMMUNOLOGY . 22(11): 1187-1196. Number of citations: 48

    [doi:10.1128/CVI.00465-15]

  • Guerra-Perez, Natalia, Ramos, Edurne, Garcia-Hernandez, Marta, Pinto, Celia, Soto, Manuel, Elena Martin, M., Gonzalez, Victor M..

    Molecular and Functional Characterization of ssDNA Aptamers that Specifically Bind Leishmania infantum PABP

    Plos One . 10(10): . Number of citations: 16

    [doi:10.1371/journal.pone.0140048]

  • Pineda MA, Cuervo H, Fresno M, Soto M, Bonay P.

    Lack of Galectin-3 Prevents Cardiac Fibrosis and Effective Immune Responses in a Murine Model of Trypanosoma cruzi Infection

    JOURNAL OF INFECTIOUS DISEASES . 212(7): 1160-1171. Number of citations: 28

    [doi:10.1093/infdis/jiv185]