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Aptamers

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  • Boaru DL, Fraile-Martinez O, De Leon-Oliva D, Garcia-Montero C, De Castro-Martinez P, Miranda-Gonzalez A, Saez MA, Muñon-Zamarron L, Castillo-Ruiz E, Barrena-Blázquez S, Cañonez-Zafra R, Alvarez-Mon MÁ, Toledo-Lobo MV, Minaya-Bravo AM, Lopez-Gonzalez L, Diaz-Pedrero R, Saz JV, Albillos A, Alvarez-Mon M, Guijarro LG, Ortega MA.

    Harnessing the Anti-Inflammatory Properties of Polyphenols in the Treatment of Inflammatory Bowel Disease.

    INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES . 20(14): 5608-5672.

    [doi:10.7150/ijbs.98107]

  • Toledano-Macias, Elena, Martinez-Pascual, Maria Antonia, Cecilia-Matilla, Almudena, Bermejo-Martinez, Mariano, Perez-Gonzalez, Alfonso, Jara, Rosa Cristina, Sacristan, Silvia, Hernandez-Bule, Maria Luisa.

    Radiofrequency Currents Modulate Inflammatory Processes in Keratinocytes

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 25(19): .

    [doi:10.3390/ijms251910663]

  • Bargiela-Cuevas S, Marin M, Gabaldon-Ojeda M, Klett-Mingo JI, Granado P, Sacristan S, Esteban-Lasso A, Casas JG, Martin ME, González VMM, Royuela M, García-Tuñon I, Ortega Núñez MA, Lobo MDVT.

    Histone Acetyl Transferase 1 Is Overexpressed in Poor Prognosis, High-grade Meningeal and Glial Brain Cancers: Immunohistochemical and Aptahistochemical Study.

    JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY . 72(8-9): 585-599.

    [doi:10.1369/00221554241272341]

  • García-Montero C, Fraile-Martinez O, Cobo-Prieto D, De Leon-Oliva D, Boaru DL, De Castro-Martinez P, Pekarek L, Gragera R, Hernández-Fernández M, Guijarro LG, Toledo-Lobo MDV, López-González L, Díaz-Pedrero R, Monserrat J, Álvarez-Mon M, Saez MA, Ortega MA.

    Abnormal Histopathological Expression of Klotho, Ferroptosis, and Circadian Clock Regulators in Pancreatic Ductal Adenocarcinoma: Prognostic Implications and Correlation Analyses.

    Biomolecules . 14(8): .

    [doi:10.3390/biom14080947]

  • Martínez-Pascual MA, Sacristán S, Toledano-Macías E, Naranjo P, Hernández-Bule ML.

    Effects of RF Electric Currents on Hair Follicle Growth and Differentiation: A Possible Treatment for Alopecia.

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 25(14): . Number of citations: 1

    [doi:10.3390/ijms25147865]

  • Ortega MA, Jiménez-Álvarez L, Fraile-Martinez O, Garcia-Montero C, Guijarro LG, Pekarek L, Barrena-Blázquez S, Asúnsolo Á, López-González L, Toledo-Lobo MDV, Álvarez-Mon M, Saez MA, Gutiérrez-Calvo A, Díaz-Pedrero R.

    Prognostic Value of Histone Acetyl Transferase 1 (HAT-1) and Inflammatory Signatures in Pancreatic Cancer.

    CURRENT ISSUES IN MOLECULAR BIOLOGY . 46(5): 3839-3865.

    [doi:10.3390/cimb46050239]

  • Sánchez-Gil MA, Fraile-Martinez O, García-Montero C, Toledo MDV, Guijarro LG, De León-Luis JA, Bravo C, Díaz-Pedrero R, López-Gonzalez L, Saez MA, Álvarez-Mon M, García-Honduvilla N, Ortega MA.

    Histopathological Clues of Enhanced Inflammation in the Placental Tissue of Women with Chronic Venous Disease in Lower Limbs during Pregnancy.

    Journal of Personalized Medicine . 14(1): . Number of citations: 2

    [doi:10.3390/jpm14010087]

  • Cilleros-Rodríguez D, Toledo-Lobo MV, Martínez-Martínez D, Baquero P, Angulo JC, Chiloeches A, Iglesias T, Lasa M.

    Protein kinase D activity is a risk biomarker in prostate cancer that drives cell invasion by a Snail/ERK dependent mechanism.

    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE . 1870(1): 166851-166851.

    [doi:10.1016/j.bbadis.2023.166851]

  • García-Fernández J, Rivadulla Costa L, Pinto-Díez C, Elena Martín M, González VM, de la Fuente Freire M.

    Chemical conjugation of aptamer-sphingomyelin nanosystems and their potential as inhibitors of tumour cell proliferation in breast cancer cells.

    Nanoscale . 15(47): 19110-19127.

    [doi:10.1039/d3nr03022a]

  • Mulens-Arias, Vladimir, Portilla, Yadileiny, Perez-Yaguee, Sonia, Ferreras-Martin, Raquel, Martin, M. Elena, Gonzalez, Victor M., Barber, Domingo F..

    An electrostatically conjugated-functional MNK1 aptamer reverts the intrinsic antitumor effect of polyethyleneimine-coated iron oxide nanoparticles in vivo in a human triple-negative cancer xenograft

    Cancer Nanotechnology . 14(1): .

    [doi:10.1186/s12645-023-00204-8]

  • Guijarro LG, Justo Bermejo FJ, Boaru DL, De Castro-Martinez P, De Leon-Oliva D, Fraile-Martínez O, Garcia-Montero C, Alvarez-Mon M, Toledo-Lobo MDV, Ortega MA.

    Is Insulin Receptor Substrate4 (IRS4) a Platform Involved in the Activation of Several Oncogenes?

    Cancers . 15(18): .

    [doi:10.3390/cancers15184651]

  • Hernández-Jiménez M, Abad-Santos F, Cotgreave I, Gallego J, Jilma B, Flores A, Jovin TG, Vivancos J, Hernández-Pérez M, Molina CA, Montaner J, Casariego J, Dalsgaard M, Liebeskind DS, Cobo E, Castellanos M, Portela PC, Masjuán J, Moniche F, Tembl JI, Terceño Izaga M, Arenillas JF, Callejas P, Olivot JM, Calviere L, Henon H, Mazighi M, Piñeiro D, Pugliese M, González VM, Moro MA, Garcia-Tornel A, Lizasoain I, Ribo M.

    Safety and Efficacy of ApTOLL in Patients With Ischemic Stroke Undergoing Endovascular Treatment: A Phase 1/2 Randomized Clinical Trial.

    JAMA NEUROLOGY . 80(8): 779-788.

    [doi:10.1001/jamaneurol.2023.1660]

  • Robledo SM, Pérez-Silanes S, Fernández-Rubio C, Poveda A, Monzote L, González VM, Alonso-Collado P, Carrión J.

    Neglected Zoonotic Diseases: Advances in the Development of Cell-Penetrating and Antimicrobial Peptides against Leishmaniosis and Chagas Disease

    PATHOGENS . 12(7): .

    [doi:10.3390/pathogens12070939]

  • Babiy B, Ramos-Molina B, Ocaña L, Sacristán S, Burgos-Santamaría D, Martínez-Botas J, Busto R, Perna C, Frutos MD, Albillos A, Pastor Ó.

    Dihydrosphingolipids are associated with steatosis and increased fibrosis damage in non-alcoholic fatty liver disease.

    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS . 1868(7): 159318-159318.

    [doi:10.1016/j.bbalip.2023.159318]

  • Colmenares R, Carrión-Marchante R, Martín ME, Salinas Muñoz L, García-Bermejo ML, Oller JC, Muñoz A, Blanco F, Rosado J, Lozano AI, Álvarez S, García-Vicente F, García G.

    Dependence of Induced Biological Damage on the Energy Distribution and Intensity of Clinical Intra-Operative Radiotherapy Electron Beams.

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 24(13): .

    [doi:10.3390/ijms241310816]

  • Sánchez-Trujillo L, Fraile-Martinez O, García-Montero C, García-Puente LM, Guijarro LG, De Leon-Oliva D, Boaru DL, Gardón-Alburquerque D, Del Val Toledo Lobo M, Royuela M, García-Tuñón I, Rios-Parra A, De León-Luis JA, Bravo C, Álvarez-Mon M, Bujan J, Saez MA, García-Honduvilla N, Ortega MA.

    Chronic Venous Disease during Pregnancy Is Related to Inflammation of the Umbilical Cord: Role of Allograft Inflammatory Factor 1 (AIF-1) and Interleukins 10 (IL-10), IL-12 and IL-18.

    Journal of Personalized Medicine . 13(6): .

    [doi:10.3390/jpm13060956]

  • Carrión-Marchante R, Pinto-Díez C, Klett-Mingo JI, Palacios E, Barragán-Usero M, Pérez-Morgado MI, Pascual-Mellado M, Alcalá S, Ruiz-Cañas L, Sainz B Jr, González VM, Martín ME.

    An Aptamer against MNK1 for Non-Small Cell Lung Cancer Treatment.

    Pharmaceutics . 15(4): .

    [doi:10.3390/pharmaceutics15041273]

  • Ortega MA, De Leon-Oliva D, Garcia-Montero C, Fraile-Martinez O, Boaru DL, Del Val Toledo Lobo M, García-Tuñón I, Royuela M, García-Honduvilla N, Bujan J, Guijarro LG, Alvarez-Mon M, Alvarez-Mon MÁ.

    Understanding HAT1: A Comprehensive Review of Noncanonical Roles and Connection with Disease.

    GENES . 14(4): .

    [doi:10.3390/genes14040915]