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Multiple Sclerosis

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  • Escobar-Villalba A, Sainz de la Maza S, Pérez Torre P, Galán JC, Rodríguez-Domínguez M, Monreal Laguillo E, Martínez Ulloa PL, Buisán Catevilla J, Corral I.

    Acute myelitis by human herpes virus 7 in an HIV-infected patient.

    JOURNAL OF CLINICAL VIROLOGY . 77: 63-65. Number of citations: 8

    [doi:10.1016/j.jcv.2016.02.001]

  • de Bock L, Fraussen J, Villar LM, Álvarez-Cermeño JC, Van Wijmeersch B, van Pesch V, Stinissen P, Somers V.

    Anti-SPAG16 antibodies in primary progressive multiple sclerosis are associated with an elevated progression index

    EUROPEAN JOURNAL OF NEUROLOGY . 23(4): 722-728. Number of citations: 8

    [doi:10.1111/ene.12925]

  • Bravo García-Morato M, Padilla-Merlano B, Nozal P, Espiño M, Juárez C, Villar LM, López-Trascasa M.

    Laboratory guidelines for the diagnosis and follow-up of patients with monoclonal gammopathies

    REVISTA CLINICA ESPANOLA . 216(3): 128-134.

    [doi:10.1016/j.rce.2015.09.002]

  • Álvarez-Cermeño JC, Muñoz-Negrete FJ, Costa-Frossard L, de la Maza SS, Villar LM, Rebolleda G.

    Intrathecal lipid-specific oligoclonal IgM synthesis associates with retinal axonal loss in multiple sclerosis.

    JOURNAL OF THE NEUROLOGICAL SCIENCES . 360: 41-44. Number of citations: 10

    [doi:10.1016/j.jns.2015.11.030]

  • Comabella M, Cantó E, Nurtdinov R, Río J, Villar LM, Picón C, Castilló J, Fissolo N, Aymerich X, Auger C, Rovira A, Montalban X.

    MRI phenotypes with high neurodegeneration are associated with peripheral blood B-cell changes

    HUMAN MOLECULAR GENETICS . 25(2): 308-316. Number of citations: 23

    [doi:10.1093/hmg/ddv473]

  • Sellebjerg F, Cadavid D, Steiner D, Villar LM, Reynolds R, Mikol D.

    Exploring potential mechanisms of action of natalizumab in secondary progressive multiple sclerosis.

    THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS . 9(1): 31-43. Number of citations: 22

    [doi:10.1177/1756285615615257]

  • Borràs E, Cantó E, Choi M, Villar LM, Álvarez-Cermeño JC, Chiva C, Montalban X, Vitek O, Comabella M, Sabidó E.

    Protein-Based Classifier to Predict Conversion from Clinically Isolated Syndrome to Multiple Sclerosis

    MOLECULAR & CELLULAR PROTEOMICS . 15(1): 318-328. Number of citations: 20

    [doi:10.1074/mcp.M115.053256]

  • Bustamante MF, Morcillo-Suárez C, Malhotra S, Rio J, Leyva L, Fernández O, Zettl UK, Killestein J, Brassat D, García-Merino JA, Sánchez AJ, Urcelay E, Alvarez-Lafuente R, Villar LM, Alvarez-Cermeño JC, Farré X, Lechner-Scott J, Vandenbroeck K, Rodríguez-Antigüedad A, Drulovic JS, Martinelli Boneschi F, Chan A, Oksenberg J, Navarro A, Montalban X, Comabella M.

    Pharmacogenomic study in patients with multiple sclerosis: Responders and nonresponders to IFN-ß.

    NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION . 2(5): . Number of citations: 16

    [doi:10.1212/NXI.0000000000000154]

  • Matesanz, Fuencisla, Potenciano, Victor, Fedetz, Maria, Ramos-Mozo, Priscila, del Mar Abad-Grau, Maria, Karaky, Mohamad, Barrionuevo, Cristina, Izquierdo, Guillermo, Luis Ruiz-Pena, Juan, Isabel Garcia-Sanchez, Maria, Lucas, Miguel, Fernandez, Oscar, Leyva, Laura, Otaegui, David, Munoz-Culla, Maider, Olascoaga, Javier, Vandenbroeck, Koen, Alloza, Iraide, Astobiza, Ianire, Antigueedad, Alfredo, Maria Villar, Luisa, Carlos Alvarez-Cermeno, Jose, Malhotra, Sunny, Comabella, Manuel, Montalban, Xavier, Saiz, Albert, Blanco, Yolanda, Arroyo, Rafael, Varade, Jezabel, Urcelay, Elena, Alcina, Antonio.

    A functional variant that affects exon-skipping and protein expression of SP140 as genetic mechanism predisposing to multiple sclerosis

    HUMAN MOLECULAR GENETICS . 24(19): 5619-5627. Number of citations: 25

    [doi:10.1093/hmg/ddv256]

  • Ortiz, Miguel A., Nunez, Concepcion, Ordonez, David, Alvarez-Cermeno, Jose C., Martinez-Rodriguez, Jose E., Sanchez, Antonio J., Arroyo, Rafael, Izquierdo, Guillermo, Malhotra, Sunny, Montalban, Xavier, Garcia-Merino, Antonio, Munteis, Elvira, Alcina, Antonio, Comabella, Manuel, Matesanz, Fuencisla, Villar, Luisa M., Urcelay, Elena.

    Influence of the LILRA3 Deletion on Multiple Sclerosis Risk: Original Data and Meta-Analysis

    Plos One . 10(8): . Number of citations: 5

    [doi:10.1371/journal.pone.0134414]

  • Delgado-Garcia, Mercedes, Matesanz, Fuencisla, Alcina, Antonio, Fedetz, Maria, Isabel Garcia-Sanchez, Maria, Luis Ruiz-Pena, Juan, Fernandez, Oscar, Pinto Medel, Maria Jesus, Leyva, Laura, Arnal, Carmen, Delgado, Concepcion, Lopez Guerrero, Jose Antonio, Gonzalez-Perez, Antonio, Saez, Maria E., Maria Villar, Luisa, Alvarez-Cermeno, Jose Carlos, Picon, Carmen, Arroyo, Rafael, Varade, Jezabel, Urcelay, Elena, Izquierdo, Guillermo, Lucas, Miguel.

    A new risk variant for multiple sclerosis at the immunoglobulin heavy chain locus associates with intrathecal IgG, IgM index and oligoclonal bands

    MULTIPLE SCLEROSIS JOURNAL . 21(9): 1104-1111. Number of citations: 9

    [doi:10.1177/1352458514556302]

  • Villar LM, Picón C, Costa-Frossard L, Alenda R, García-Caldentey J, Espiño M, Muriel A, Álvarez-Cermeño JC.

    Cerebrospinal fluid immunological biomarkers associated with axonal damage in multiple sclerosis

    EUROPEAN JOURNAL OF NEUROLOGY . 22(8): 1169-1175. Number of citations: 40

    [doi:10.1111/ene.12579]

  • Kuhle, J., Disanto, G., Dobson, R., Adiutori, R., Bianchi, L., Topping, J., Bestwick, J. P., Meier, U-C, Marta, M., Dalla Costa, G., Runia, T., Evdoshenko, E., Lazareva, N., Thouvenot, E., Iaffaldano, P., Direnzo, V., Khademi, M., Piehl, F., Comabella, M., Sombekke, M., Killestein, J., Hegen, H., Rauch, S., D'Alfonso, S., Alvarez-Cermeno, J. C., Kleinova, P., Horakova, D., Roesler, R., Lauda, F., Llufriu, S., Avsar, T., Uygunoglu, U., Altintas, A., Saip, S., Menge, T., Rajda, C., Bergamaschi, R., Moll, N., Khalil, M., Marignier, R., Dujmovic, I., Larsson, H., Malmestrom, C., Scarpini, E., Fenoglio, C., Wergeland, S., Laroni, A., Annibali, V., Romano, S., Martinez, A. D., Carra, A., Salvetti, M., Uccelli, A., Torkildsen, O., Myhr, K. M., Galimberti, D., Rejdak, K., Lycke, J., Frederiksen, J. L., Drulovic, J., Confavreux, C., Brassat, D., Enzinger, C., Fuchs, S., Bosca, I., Pelletier, J., Picard, C., Colombo, E., Franciotta, D., Derfuss, T., Lindberg, R. L. P., Yaldizli, Oe, Vecsei, L., Kieseier, B. C., Hartung, H. P., Villoslada, P., Siva, A., Saiz, A., Tumani, H., Havrdova, E., Villar, L. M., Leone, M., Barizzone, N., Deisenhammer, F., Teunissen, C., Montalban, X., Tintore, M., Olsson, T., Trojano, M., Lehmann, S., Castelnovo, G., Lapin, S., Hintzen, R., Kappos, L., Furlan, R., Martinelli, V., Comi, G., Ramagopalan, S. V., Giovannoni, G..

    Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study

    MULTIPLE SCLEROSIS JOURNAL . 21(8): 1013-1024. Number of citations: 170

    [doi:10.1177/1352458514568827]

  • Fernández O, García-Merino JA, Arroyo R, Álvarez-Cermeño JC, Izquierdo G, Saiz A, Olascoaga J, Rodríguez-Antigüedad A, Prieto JM, Oreja-Guevara C, Hernández MA, Moral E, Meca J, Montalbán X.

    Spanish consensus on the use of natalizumab (Tysabri (R))-2013

    NEUROLOGIA . 30(5): 302-314. Number of citations: 7

    [doi:10.1016/j.nrl.2013.10.004]

  • Rodríguez-Martín E, Picón C, Costa-Frossard L, Alenda R, Sainz de la Maza S, Roldán E, Espiño M, Villar LM, Álvarez-Cermeño JC.

    Natural killer cell subsets in cerebrospinal fluid of patients with multiple sclerosis

    CLINICAL AND EXPERIMENTAL IMMUNOLOGY . 180(2): 243-249. Number of citations: 38

    [doi:10.1111/cei.12580]

  • Cantó E, Tintoré M, Villar LM, Costa C, Nurtdinov R, Álvarez-Cermeño JC, Arrambide G, Reverter F, Deisenhammer F, Hegen H, Khademi M, Olsson T, Tumani H, Rodríguez-Martín E, Piehl F, Bartos A, Zimova D, Kotoucova J, Kuhle J, Kappos L, García-Merino JA, Sánchez AJ, Saiz A, Blanco Y, Hintzen R, Jafari N, Brassat D, Lauda F, Roesler R, Rejdak K, Papuc E, de Andrés C, Rauch S, Khalil M, Enzinger C, Galimberti D, Scarpini E, Teunissen C, Sánchez A, Rovira A, Montalban X, Comabella M.

    Chitinase 3-like 1: prognostic biomarker in clinically isolated syndromes

    Brain . 138(4): 918-931. Number of citations: 103

    [doi:10.1093/brain/awv017]

  • Villar LM, Costa-Frossard L, Masterman T, Fernandez O, Montalban X, Casanova B, Izquierdo G, Coret F, Tumani H, Saiz A, Arroyo R, Fink K, Leyva L, Espejo C, Simó-Castelló M, García-Sánchez MI, Lauda F, Llufriú S, Álvarez-Lafuente R, Olascoaga J, Prada A, Oterino A, de Andrés C, Tintoré M, Ramió-Torrentà L, Rodríguez-Martín E, Picón C, Comabella M, Quintana E, Agüera E, Díaz S, Fernandez-Bolaños R, García-Merino JA, Landete L, Menéndez-González M, Navarro L, Pérez D, Sánchez-López F, Serrano-Castro PJ, Tuñón A, Espiño M, Muriel A, Bar-Or A, Álvarez-Cermeño JC.

    Lipid-Specific Immunoglobulin M Bands in Cerebrospinal Fluid Are Associated with a Reduced Risk of Developing Progressive Multifocal Leukoencephalopathy during Treatment with Natalizumab

    ANNALS OF NEUROLOGY . 77(3): 447-457. Number of citations: 46

    [doi:10.1002/ana.24345]

  • Espino, M., Abraira, V., Arroyo, R., Bau, L., Camara, C., Campos-Ruiz, L., Casanova, B., Espejo, C., Fernandez, O., Garcia-Merino, A., Garcia-Sanchez, M. I., Gomez, M., Gosis, A., Izquierdo, G., Meca, J., Montalban, X., Morandeira, F., Olascoaga, J., Prada, A., Quintana, E., Ramio-Torrenta, Ll., Rodriguez-Antigueedad, A., Salgado, G., Santiago, J. L., Sarasola, E., Simo-Castello, M., Alvarez-Cermeno, J. C., Villar, L. M..

    Assessment of the reproducibility of oligoclonal IgM band detection for its application in daily clinical practice

    CLINICA CHIMICA ACTA . 438: 67-69. Number of citations: 13

    [doi:10.1016/j.cca.2014.08.004]