Multiple Sclerosis

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  • Sellebjerg F, Cadavid D, Steiner D, Villar LM, Reynolds R, Mikol D.

    Exploring potential mechanisms of action of natalizumab in secondary progressive multiple sclerosis.

    THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS . 9(1): 31-43. Number of citations: 22

    [doi:10.1177/1756285615615257]

  • Borràs E, Cantó E, Choi M, Villar LM, Álvarez-Cermeño JC, Chiva C, Montalban X, Vitek O, Comabella M, Sabidó E.

    Protein-Based Classifier to Predict Conversion from Clinically Isolated Syndrome to Multiple Sclerosis

    MOLECULAR & CELLULAR PROTEOMICS . 15(1): 318-328. Number of citations: 20

    [doi:10.1074/mcp.M115.053256]

  • Bustamante MF, Morcillo-Suárez C, Malhotra S, Rio J, Leyva L, Fernández O, Zettl UK, Killestein J, Brassat D, García-Merino JA, Sánchez AJ, Urcelay E, Alvarez-Lafuente R, Villar LM, Alvarez-Cermeño JC, Farré X, Lechner-Scott J, Vandenbroeck K, Rodríguez-Antigüedad A, Drulovic JS, Martinelli Boneschi F, Chan A, Oksenberg J, Navarro A, Montalban X, Comabella M.

    Pharmacogenomic study in patients with multiple sclerosis: Responders and nonresponders to IFN-ß.

    Neurology(R) neuroimmunology & neuroinflammation . 2(5): . Number of citations: 16

    [doi:10.1212/NXI.0000000000000154]

  • Matesanz, Fuencisla, Potenciano, Victor, Fedetz, Maria, Ramos-Mozo, Priscila, del Mar Abad-Grau, Maria, Karaky, Mohamad, Barrionuevo, Cristina, Izquierdo, Guillermo, Luis Ruiz-Pena, Juan, Isabel Garcia-Sanchez, Maria, Lucas, Miguel, Fernandez, Oscar, Leyva, Laura, Otaegui, David, Munoz-Culla, Maider, Olascoaga, Javier, Vandenbroeck, Koen, Alloza, Iraide, Astobiza, Ianire, Antigueedad, Alfredo, Maria Villar, Luisa, Carlos Alvarez-Cermeno, Jose, Malhotra, Sunny, Comabella, Manuel, Montalban, Xavier, Saiz, Albert, Blanco, Yolanda, Arroyo, Rafael, Varade, Jezabel, Urcelay, Elena, Alcina, Antonio.

    A functional variant that affects exon-skipping and protein expression of SP140 as genetic mechanism predisposing to multiple sclerosis

    HUMAN MOLECULAR GENETICS . 24(19): 5619-5627. Number of citations: 25

    [doi:10.1093/hmg/ddv256]

  • Ortiz, Miguel A., Nunez, Concepcion, Ordonez, David, Alvarez-Cermeno, Jose C., Martinez-Rodriguez, Jose E., Sanchez, Antonio J., Arroyo, Rafael, Izquierdo, Guillermo, Malhotra, Sunny, Montalban, Xavier, Garcia-Merino, Antonio, Munteis, Elvira, Alcina, Antonio, Comabella, Manuel, Matesanz, Fuencisla, Villar, Luisa M., Urcelay, Elena.

    Influence of the LILRA3 Deletion on Multiple Sclerosis Risk: Original Data and Meta-Analysis

    Plos One . 10(8): . Number of citations: 5

    [doi:10.1371/journal.pone.0134414]

  • Delgado-Garcia, Mercedes, Matesanz, Fuencisla, Alcina, Antonio, Fedetz, Maria, Isabel Garcia-Sanchez, Maria, Luis Ruiz-Pena, Juan, Fernandez, Oscar, Pinto Medel, Maria Jesus, Leyva, Laura, Arnal, Carmen, Delgado, Concepcion, Lopez Guerrero, Jose Antonio, Gonzalez-Perez, Antonio, Saez, Maria E., Maria Villar, Luisa, Alvarez-Cermeno, Jose Carlos, Picon, Carmen, Arroyo, Rafael, Varade, Jezabel, Urcelay, Elena, Izquierdo, Guillermo, Lucas, Miguel.

    A new risk variant for multiple sclerosis at the immunoglobulin heavy chain locus associates with intrathecal IgG, IgM index and oligoclonal bands

    MULTIPLE SCLEROSIS JOURNAL . 21(9): 1104-1111. Number of citations: 9

    [doi:10.1177/1352458514556302]

  • Villar LM, Picón C, Costa-Frossard L, Alenda R, García-Caldentey J, Espiño M, Muriel A, Álvarez-Cermeño JC.

    Cerebrospinal fluid immunological biomarkers associated with axonal damage in multiple sclerosis

    EUROPEAN JOURNAL OF NEUROLOGY . 22(8): 1169-1175. Number of citations: 40

    [doi:10.1111/ene.12579]

  • Kuhle, J., Disanto, G., Dobson, R., Adiutori, R., Bianchi, L., Topping, J., Bestwick, J. P., Meier, U-C, Marta, M., Dalla Costa, G., Runia, T., Evdoshenko, E., Lazareva, N., Thouvenot, E., Iaffaldano, P., Direnzo, V., Khademi, M., Piehl, F., Comabella, M., Sombekke, M., Killestein, J., Hegen, H., Rauch, S., D'Alfonso, S., Alvarez-Cermeno, J. C., Kleinova, P., Horakova, D., Roesler, R., Lauda, F., Llufriu, S., Avsar, T., Uygunoglu, U., Altintas, A., Saip, S., Menge, T., Rajda, C., Bergamaschi, R., Moll, N., Khalil, M., Marignier, R., Dujmovic, I., Larsson, H., Malmestrom, C., Scarpini, E., Fenoglio, C., Wergeland, S., Laroni, A., Annibali, V., Romano, S., Martinez, A. D., Carra, A., Salvetti, M., Uccelli, A., Torkildsen, O., Myhr, K. M., Galimberti, D., Rejdak, K., Lycke, J., Frederiksen, J. L., Drulovic, J., Confavreux, C., Brassat, D., Enzinger, C., Fuchs, S., Bosca, I., Pelletier, J., Picard, C., Colombo, E., Franciotta, D., Derfuss, T., Lindberg, R. L. P., Yaldizli, Oe, Vecsei, L., Kieseier, B. C., Hartung, H. P., Villoslada, P., Siva, A., Saiz, A., Tumani, H., Havrdova, E., Villar, L. M., Leone, M., Barizzone, N., Deisenhammer, F., Teunissen, C., Montalban, X., Tintore, M., Olsson, T., Trojano, M., Lehmann, S., Castelnovo, G., Lapin, S., Hintzen, R., Kappos, L., Furlan, R., Martinelli, V., Comi, G., Ramagopalan, S. V., Giovannoni, G..

    Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study

    MULTIPLE SCLEROSIS JOURNAL . 21(8): 1013-1024. Number of citations: 170

    [doi:10.1177/1352458514568827]

  • Fernández O, García-Merino JA, Arroyo R, Álvarez-Cermeño JC, Izquierdo G, Saiz A, Olascoaga J, Rodríguez-Antigüedad A, Prieto JM, Oreja-Guevara C, Hernández MA, Moral E, Meca J, Montalbán X.

    Spanish consensus on the use of natalizumab (Tysabri (R))-2013

    NEUROLOGIA . 30(5): 302-314. Number of citations: 7

    [doi:10.1016/j.nrl.2013.10.004]

  • Rodríguez-Martín E, Picón C, Costa-Frossard L, Alenda R, Sainz de la Maza S, Roldán E, Espiño M, Villar LM, Álvarez-Cermeño JC.

    Natural killer cell subsets in cerebrospinal fluid of patients with multiple sclerosis

    CLINICAL AND EXPERIMENTAL IMMUNOLOGY . 180(2): 243-249. Number of citations: 38

    [doi:10.1111/cei.12580]

  • Cantó E, Tintoré M, Villar LM, Costa C, Nurtdinov R, Álvarez-Cermeño JC, Arrambide G, Reverter F, Deisenhammer F, Hegen H, Khademi M, Olsson T, Tumani H, Rodríguez-Martín E, Piehl F, Bartos A, Zimova D, Kotoucova J, Kuhle J, Kappos L, García-Merino JA, Sánchez AJ, Saiz A, Blanco Y, Hintzen R, Jafari N, Brassat D, Lauda F, Roesler R, Rejdak K, Papuc E, de Andrés C, Rauch S, Khalil M, Enzinger C, Galimberti D, Scarpini E, Teunissen C, Sánchez A, Rovira A, Montalban X, Comabella M.

    Chitinase 3-like 1: prognostic biomarker in clinically isolated syndromes

    Brain . 138(4): 918-931. Number of citations: 103

    [doi:10.1093/brain/awv017]

  • Villar LM, Costa-Frossard L, Masterman T, Fernandez O, Montalban X, Casanova B, Izquierdo G, Coret F, Tumani H, Saiz A, Arroyo R, Fink K, Leyva L, Espejo C, Simó-Castelló M, García-Sánchez MI, Lauda F, Llufriú S, Álvarez-Lafuente R, Olascoaga J, Prada A, Oterino A, de Andrés C, Tintoré M, Ramió-Torrentà L, Rodríguez-Martín E, Picón C, Comabella M, Quintana E, Agüera E, Díaz S, Fernandez-Bolaños R, García-Merino JA, Landete L, Menéndez-González M, Navarro L, Pérez D, Sánchez-López F, Serrano-Castro PJ, Tuñón A, Espiño M, Muriel A, Bar-Or A, Álvarez-Cermeño JC.

    Lipid-Specific Immunoglobulin M Bands in Cerebrospinal Fluid Are Associated with a Reduced Risk of Developing Progressive Multifocal Leukoencephalopathy during Treatment with Natalizumab

    ANNALS OF NEUROLOGY . 77(3): 447-457. Number of citations: 46

    [doi:10.1002/ana.24345]

  • Espino, M., Abraira, V., Arroyo, R., Bau, L., Camara, C., Campos-Ruiz, L., Casanova, B., Espejo, C., Fernandez, O., Garcia-Merino, A., Garcia-Sanchez, M. I., Gomez, M., Gosis, A., Izquierdo, G., Meca, J., Montalban, X., Morandeira, F., Olascoaga, J., Prada, A., Quintana, E., Ramio-Torrenta, Ll., Rodriguez-Antigueedad, A., Salgado, G., Santiago, J. L., Sarasola, E., Simo-Castello, M., Alvarez-Cermeno, J. C., Villar, L. M..

    Assessment of the reproducibility of oligoclonal IgM band detection for its application in daily clinical practice

    CLINICA CHIMICA ACTA . 438: 67-69. Number of citations: 13

    [doi:10.1016/j.cca.2014.08.004]

  • de la Hera B, Urcelay E, Brassat D, Chan A, Vidal-Jordana A, Salmen A, Villar LM, Alvarez-Cermeño JC, Izquierdo G, Fernández O, Oliver B, Saiz A, Ara JR, Vigo AG, Arroyo R, Meca V, Malhotra S, Fissolo N, Horga A, Montalban X, Comabella M.

    Natalizumab-related anaphylactoid reactions in MS patients are associated with HLA class II alleles.

    Neurology(R) neuroimmunology & neuroinflammation . 1(4): .

    [doi:10.1212/NXI.0000000000000047]

  • Cantó E, Tintoré M, Villar LM, Borrás E, Alvarez-Cermeño JC, Chiva C, Sabidó E, Rovira A, Montalban X, Comabella M.

    Validation of semaphorin 7A and ala-beta-his-dipeptidase as biomarkers associated with the conversion from clinically isolated syndrome to multiple sclerosis

    JOURNAL OF NEUROINFLAMMATION . 11: 181-181. Number of citations: 19

    [doi:10.1186/s12974-014-0181-8]

  • Fernández Ó, Álvarez-Cermeño JC, Arnal-García C, Arroyo-González R, Brieva L, Calles-Hernández MC, Casanova-Estruch B, Comabella M, García-Merino JA, Izquierdo G, Meca-Lallana J, Mendibe-Bilbao Mdel M, Muñoz-García D, Olascoaga J, Oliva-Nacarino P, Oreja-Guevara C, Prieto J, Ramió-Torrentà L, Romero-Pinel L, Saiz A, Rodríguez-Antigüedad A, Grupo Post-ECTRIMS.

    Review of the novelties presented at the 29th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) (III)

    REVISTA DE NEUROLOGIA . 59(8): 371-379. Number of citations: 4

    [doi:10.33588/rn.5908.2014335]

  • Fernández Ó, Álvarez-Cermeño JC, Arnal-García C, Arroyo-González R, Brieva L, Calles-Hernández MC, Casanova-Estruch B, Comabella M, García-Merino JA, Izquierdo G, Meca-Lallana JE, Mendibe-Bilbao Mdel M, Muñoz-García D, Olascoaga J, Oliva-Nacarino P, Oreja-Guevara C, Prieto J, Ramió-Torrentà L, Romero-Pinel L, Saiz A, Rodríguez-Antigüedad A.

    [Review of the novelties presented at the 29th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) (II)].

    REVISTA DE NEUROLOGIA . 59(7): 307-316. Number of citations: 1

    [doi:10.33588/rn.5907.2014334]

  • Beltrán E, Obermeier B, Moser M, Coret F, Simó-Castelló M, Boscá I, Pérez-Miralles F, Villar LM, Senel M, Tumani H, Hohlfeld R, Casanova B, Dornmair K.

    Intrathecal somatic hypermutation of IgM in multiple sclerosis and neuroinflammation

    Brain . 137(10): 2703-2714. Number of citations: 50

    [doi:10.1093/brain/awu205]