1. Home
  2. Research
  3. Research Groups
  4. Multiple Sclerosis

Multiple Sclerosis

Search for publications

Only original articles, editorials, guidelines.

  • Alonso-Canovas A, Lopez-Sendon Moreno JL, Buisan J, Sainz de la Maza S, Costa-Frossard L, Garcia-Ribas G, de Felipe-Mimbrera A, Matute-Lozano MC, Zarza Sanz B, Toledano Delgado R, Corral I, Masjuan J, Martinez-Castrillo JC.

    Does normal substantia nigra echogenicity make a difference in Parkinson's disease diagnosis? A real clinical practice follow-up study.

    JOURNAL OF NEUROLOGY . 265(10): 2363-2369. Number of citations: 3

    [doi:10.1007/s00415-018-9006-5]

  • Malhotra S, Sorosina M, Río J, Peroni S, Midaglia L, Villar LM, Álvarez-Cermeño JC, Schroeder I, Esposito F, Clarelli F, Zettl UK, Lechner-Scott J, Spataro N, Navarro A, Comi G, Montalban X, Martinelli-Boneschi F, Comabella M.

    NLRP3 polymorphisms and response to interferon-beta in multiple sclerosis patients.

    MULTIPLE SCLEROSIS JOURNAL . 24(11): 1507-1510. Number of citations: 6

    [doi:10.1177/1352458517739137]

  • Gil-Varea E, Urcelay E, Vilariño-Güell C, Costa C, Midaglia L, Matesanz F, Rodríguez-Antigüedad A, Oksenberg J, Espino-Paisan L, Dessa Sadovnick A, Saiz A, Villar LM, García-Merino JA, Ramió-Torrentà L, Triviño JC, Quintana E, Robles R, Sánchez-López A, Arroyo R, Alvarez-Cermeño JC, Vidal-Jordana A, Malhotra S, Fissolo N, Montalban X, Comabella M.

    Exome sequencing study in patients with multiple sclerosis reveals variants associated with disease course.

    JOURNAL OF NEUROINFLAMMATION . 15(1): 265-265. Number of citations: 17

    [doi:10.1186/s12974-018-1307-1]

  • Quintana E, Coll C, Salavedra-Pont J, Muñoz-San Martín M, Robles-Cedeño R, Tomàs-Roig J, Buxó M, Matute-Blanch C, Villar LM, Montalban X, Comabella M, Perkal H, Gich J, Ramió-Torrentà LL.

    Cognitive impairment in early stages of multiple sclerosis is associated with high cerebrospinal fluid levels of chitinase 3-like 1 and neurofilament light chain.

    EUROPEAN JOURNAL OF NEUROLOGY . 25(9): 1189-1191. Number of citations: 36

    [doi:10.1111/ene.13687]

  • Medina S, Villarrubia N, Sainz de la Maza S, Lifante J, Costa-Frossard L, Roldán E, Picón C, Álvarez-Cermeño JC, Villar LM.

    Optimal response to dimethyl fumarate associates in MS with a shift from an inflammatory to a tolerogenic blood cell profile.

    MULTIPLE SCLEROSIS JOURNAL . 24(10): 1317-1327. Number of citations: 30

    [doi:10.1177/1352458517717088]

  • Szejko N, Picón C, García-Caldentey J, de Yebenes JG, Alvarez-Cermeño JC, Villar LM, López-Sendón Moreno JL.

    Quantification of the Light Subunit of Neurofilament Protein in Cerebrospinal Fluid of Huntington's Disease Patients.

    PLoS currents . 10: .

    [doi:10.1371/currents.hd.280c8f9f7d9fa4f7f0c883d9f8e807da]

  • Casanova B, Lacruz L, Villar ML, Domínguez JA, Gadea MC, Gascón F, Mallada J, Hervás D, Simó-Castelló M, Álvarez-Cermeño JC, Calles C, Olascoaga J, Ramió-Torrentà L, Alcalá C, Cervelló A, Boscá I, Pérez-Mirallles FC, Coret F.

    Different clinical response to interferon beta and glatiramer acetate related to the presence of oligoclonal IgM bands in CSF in multiple sclerosis patients.

    NEUROLOGICAL SCIENCES . 39(8): 1423-1430. Number of citations: 4

    [doi:10.1007/s10072-018-3442-y]

  • Alari-Pahissa E, Moreira A, Zabalza A, Alvarez-Lafuente R, Munteis E, Vera A, Arroyo R, Alvarez-Cermeño JC, Villar LM, López-Botet M, Martínez-Rodríguez JE.

    Low cytomegalovirus seroprevalence in early multiple sclerosis: a case for the 'hygiene hypothesis'?

    EUROPEAN JOURNAL OF NEUROLOGY . 25(7): 925-933. Number of citations: 12

    [doi:10.1111/ene.13622]

  • Corral Í, Sainz de la Maza S, Rodríguez M, Kawiorski MM, López-Martínez MJ, Galán JC.

    Molecular detection of human herpesvirus 7 DNA in cerebrospinal fluid from adult patients with neurological disorders.

    JOURNAL OF NEUROVIROLOGY . 24(3): 333-338. Number of citations: 5

    [doi:10.1007/s13365-018-0618-4]

  • Ramió-Torrentà L, Álvarez-Cermeño JC, Arroyo R, Casanova-Estruch B, Fernández O, García-Merino JA, Hernández MA, Izquierdo G, Martínez-Yélamos S, Meca J, Moral E, Olascoaga J, Prieto JM, Saiz A.

    A guide to treating gait impairment with prolonged-release fampridine (Fampyra (R)) in patients with multiple sclerosis

    NEUROLOGIA . 33(5): 327-337. Number of citations: 2

    [doi:10.1016/j.nrl.7015.11.013]

  • Bravo García-Morato M, Aracil Santos FJ, Briones AC, Blázquez Moreno A, Del Pozo Maté Á, Domínguez-Soto Á, Beato Merino MJ, Del Pino Molina L, Torres Canizales J, Marin AV, Vallespín García E, Feito Rodríguez M, Plaza López Sabando D, Jiménez-Reinoso A, Mozo Del Castillo Y, Sanz Santaeufemia FJ, de Lucas-Laguna R, Cárdenas PP, Casamayor Polo L, Coronel Díaz M, Valés-Gómez M, Roldán Santiago E, Ferreira Cerdán A, Nevado Blanco J, Corbí ÁL, Reyburn HT, Regueiro JR, López-Granados E, Rodríguez Pena R.

    New human combined immunodeficiency caused by interferon regulatory factor 4 (IRF4) deficiency inherited by uniparental isodisomy.

    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY . 141(5): 1924. Number of citations: 8

    [doi:10.1016/j.jaci.2017.12.995]

  • Matute-Blanch C, Villar LM, Álvarez-Cermeño JC, Rejdak K, Evdoshenko E, Makshakov G, Nazarov V, Lapin S, Midaglia L, Vidal-Jordana A, Drulovic J, García-Merino A, Sánchez-López AJ, Havrdova E, Saiz A, Llufriu S, Alvarez-Lafuente R, Schroeder I, Zettl UK, Galimberti D, Ramió-Torrentà L, Robles R, Quintana E, Hegen H, Deisenhammer F, Río J, Tintoré M, Sánchez A, Montalban X, Comabella M.

    Neurofilament light chain and oligoclonal bands are prognostic biomarkers in radiologically isolated syndrome.

    Brain . 141(4): 1085-1093. Number of citations: 71

    [doi:10.1093/brain/awy021]

  • Tejeda-Velarde A, Costa-Frossard L, de la Maza SS, Carrasco Á, Espiño M, Picón C, Toboso I, Walo PE, Lourido D, Muriel A, Álvarez-Cermeño JC, Villar LM.

    Clinical usefulness of prognostic biomarkers in optic neuritis.

    EUROPEAN JOURNAL OF NEUROLOGY . 25(4): 614-618. Number of citations: 10

    [doi:10.1111/ene.13553]

  • Frau J, Villar LM, Sardu C, Secci MA, Schirru L, Ferraro D, Coghe G, Lorefice L, Fenu G, Bedin R, Sola P, Marrosu MG, Cocco E.

    Intrathecal oligoclonal bands synthesis in multiple sclerosis: is it always a prognostic factor?

    JOURNAL OF NEUROLOGY . 265(2): 424-430. Number of citations: 13

    [doi:10.1007/s00415-017-8716-4]

  • Alenda R, Costa-Frossard L, Alvarez-Lafuente R, Espejo C, Rodríguez-Martín E, Sainz de la Maza S, Villarrubia N, Río J, Domínguez-Mozo MI, Montalban X, Álvarez-Cermeño JC, Villar LM.

    Correction to: Blood lymphocyte subsets identify optimal responders to IFN-beta in MS.

    JOURNAL OF NEUROLOGY . 265(1): 32-32.

    [doi:10.1007/s00415-017-8679-5]

  • Alenda R, Costa-Frossard L, Alvarez-Lafuente R, Espejo C, Rodríguez-Martín E, de la Maza SS, Villarrubia N, Río J, Domínguez-Mozo MI, Montalban X, Álvarez-Cermeño JC, Villar LM.

    Blood lymphocyte subsets identify optimal responders to IFN-beta in MS.

    JOURNAL OF NEUROLOGY . 265(1): 24-31. Number of citations: 10

    [doi:10.1007/s00415-017-8625-6]

  • Quintana E, Ortega FJ, Robles-Cedeño R, Villar ML, Buxó M, Mercader JM, Alvarez-Cermeño JC, Pueyo N, Perkal H, Fernández-Real JM, Ramió-Torrentà L.

    miRNAs in cerebrospinal fluid identify patients with MS and specifically those with lipid-specific oligoclonal IgM bands.

    MULTIPLE SCLEROSIS JOURNAL . 23(13): 1716-1726. Number of citations: 39

    [doi:10.1177/1352458516684213]

  • Fernández-Paredes L, Casrouge A, Decalf J, de Andrés C, Villar LM, Pérez de Diego R, Alonso B, Álvarez Cermeño JC, Arroyo R, Tejera-Alhambra M, Navarro J, Oreja-Guevara C, López Trascasa M, Seyfferth A, García Martínez MA, Álvarez Lafuente R, Albert ML, Sánchez-Ramón S.

    Multimarker risk stratification approach at multiple sclerosis onset.

    CLINICAL IMMUNOLOGY . 181: 43-50. Number of citations: 9

    [doi:10.1016/j.clim.2017.05.019]