Multiple Sclerosis

Group leader

Luisa María Villar Guimerans

luisamaria.villar(ELIMINAR)@salud.madrid.org

Tlf.: 0034 913368029

Principal Investigator

  • Eulalia Rodríguez Martín

Collaborating Staff

  • María Mercedes Espiño Martínez
  • Ernesto Roldán Santiago
  • Lucienne Costa-Frossard França
  • Susana Sainz de la Maza Cantero
  • Enric Monreal Laguillo
  • José Ignacio Fernández Velasco
  • Noelia Villarrubia Migallón
  • Roberto Pariente Rodríguez
  • Alexander Rodero Romero
  • Juan Luis Chico Garcia
  • Fernando Rodríguez Jorge
  • Paula Batres Faba
  • Raquel Sainz Amo
  • José Luis Veiga González
  • María Eugenia Martín Villasevil
Imagen equipo

Group leader

Luisa María Villar Guimerans

luisamaria.villar(ELIMINAR)@salud.madrid.org

Tlf.: 0034 913368029

Principal Investigator

  • Eulalia Rodríguez Martín

Collaborating Staff

  • María Mercedes Espiño Martínez
  • Ernesto Roldán Santiago
  • Lucienne Costa-Frossard França
  • Susana Sainz de la Maza Cantero
  • Enric Monreal Laguillo
  • José Ignacio Fernández Velasco
  • Noelia Villarrubia Migallón
  • Roberto Pariente Rodríguez
  • Alexander Rodero Romero
  • Juan Luis Chico Garcia
  • Fernando Rodríguez Jorge
  • Paula Batres Faba
  • Raquel Sainz Amo
  • José Luis Veiga González
  • María Eugenia Martín Villasevil

Strategic Objectives

  • Deepen the study of the pathophysiological mechanisms of MS in order to identify new therapeutic targets for the disease and contribute to the personalized treatment of patients.
  • Study the mechanisms associated with progressive forms of the disease, for which there is only one currently approved treatment.
  • Identify immunological factors that early predict the risk of progression in MS in order to establish personalized therapy for this disease.
  • Evaluate biomarkers of response to treatment and identify patients at risk of serious side effects.
  • Study environmental factors that play a role in the course of the disease, to see if modifying them could have a beneficial effect on patients.

Research Lines

  • Search for biomarkers that identify the best benefit/risk profile for different biologic therapies in MS.
  • Search for biomarkers to identify the risk of progression in MS.
  • Immunological mechanisms that are associated with primarily progressive forms of MS.
  • Association of antibodies to Epstein-Barr virus and clinical and immunologic phenotype in MS.
  • Study of the response to vaccines against SARS-CoV-2 in MS.
  • Study of pathological mechanisms in MS.

Location

Laboratory:

Immunology Service. 1st floor left.

Clinical Unit:

Neurology Service: 2nd floor center.          
Ramón y Cajal University Hospital

Keywords

multiple sclerosis (MS), biomarkers, immunological mechanisms, B cells, antibodies.