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Biomarcadores y Abordaje Personalizado del Cáncer (BioPAC)

Buscador de publicaciones

Sólo se han incluido artículos originales, editoriales y revisiones.

  • Díaz-Alejo JF, April-Monn S, Cihova M, Buocikova V, Villalón López J, Urbanova M, Lechuga CG, Tomas M, Dubovan P, Sánchez BL, Páez SC, Sanjuanbenito A, Lobo E, Romio de la Heras E, Guerra C, de la Pinta C, Barreto Melian E, Rodríguez Garrote M, Carrato A, Ruiz-Cañas L, Sainz B Jr, Torres A, Smolkova B, Earl J.

    Establishment of Pancreatic Cancer-Derived Tumor Organoids and Fibroblasts From Fresh Tissue

    JOVE-JOURNAL OF VISUALIZED EXPERIMENTS . (195): . Nº de citas: 1

    [doi:10.3791/65229]

  • Carrión-Marchante R, Pinto-Díez C, Klett-Mingo JI, Palacios E, Barragán-Usero M, Pérez-Morgado MI, Pascual-Mellado M, Alcalá S, Ruiz-Cañas L, Sainz B Jr, González VM, Martín ME.

    An Aptamer against MNK1 for Non-Small Cell Lung Cancer Treatment.

    Pharmaceutics . 15(4): .

    [doi:10.3390/pharmaceutics15041273]

  • Frank KJ, Mulero-Sánchez A, Berninger A, Ruiz-Cañas L, Bosma A, Görgülü K, Wu N, Diakopoulos KN, Kaya-Aksoy E, Ruess DA, Kabacaoglu D, Schmidt F, Kohlmann L, van Tellingen O, Thijssen B, van de Ven M, Proost N, Kossatz S, Weber WA, Sainz B Jr, Bernards R, Algül H, Lesina M, Mainardi S.

    Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer.

    CELL REPORTS MEDICINE . 3(11): 100815-100815.

    [doi:10.1016/j.xcrm.2022.100815]

  • Cave DD, Buonaiuto S, Sainz B Jr, Fantuz M, Mangini M, Carrer A, Di Domenico A, Iavazzo TT, Andolfi G, Cortina C, Sevillano M, Heeschen C, Colonna V, Corona M, Cucciardi A, Di Guida M, Batlle E, De Luca A, Lonardo E.

    LAMC2 marks a tumor-initiating cell population with an aggressive signature in pancreatic cancer.

    Journal Of Experimental & Clinical Cancer Research . 41(1): 315-315. Nº de citas: 1

    [doi:10.1186/s13046-022-02516-w]

  • Alonso-Nocelo M, Ruiz-Cañas L, Sancho P, Görgülü K, Alcalá S, Pedrero C, Vallespinos M, López-Gil JC, Ochando M, García-García E, David Trabulo SM, Martinelli P, Sánchez-Tomero P, Sánchez-Palomo C, Gonzalez-Santamaría P, Yuste L, Wörmann SM, Kabacaoglu D, Earl J, Martin A, Salvador F, Valle S, Martin-Hijano L, Carrato A, Erkan M, García-Bermejo L, Hermann PC, Algül H, Moreno-Bueno G, Heeschen C, Portillo F, Cano A, Sainz B Jr.

    Macrophages direct cancer cells through a LOXL2-mediated metastatic cascade in pancreatic ductal adenocarcinoma.

    Gut . 72(2): 345-359. Nº de citas: 3

    [doi:10.1136/gutjnl-2021-325564]

  • Muñoz Velasco R, Jiménez Sánchez P, García García A, Blanco Martinez-Illescas R, Pastor Senovilla Á, Lozano Yagüe M, Trento A, García-Martin RM, Navarro D, Sainz B Jr, Rodríguez Peralto JL, Sánchez-Arévalo Lobo VJ.

    Targeting BPTF Sensitizes Pancreatic Ductal Adenocarcinoma to Chemotherapy by Repressing ABC-Transporters and Impairing Multidrug Resistance (MDR).

    Cancers . 14(6): .

    [doi:10.3390/cancers14061518]

  • Alors-Perez E, Blázquez-Encinas R, Alcalá S, Viyuela-García C, Pedraza-Arevalo S, Herrero-Aguayo V, Jiménez-Vacas JM, Mafficini A, Sánchez-Frías ME, Cano MT, Abollo-Jiménez F, Marín-Sanz JA, Cabezas-Sainz P, Lawlor RT, Luchini C, Sánchez L, Sánchez-Hidalgo JM, Ventura S, Martin-Hijano L, Gahete MD, Scarpa A, Arjona-Sánchez Á, Ibáñez-Costa A, Sainz B Jr, Luque RM, Castaño JP.

    Dysregulated splicing factor SF3B1 unveils a dual therapeutic vulnerability to target pancreatic cancer cells and cancer stem cells with an anti-splicing drug

    Journal Of Experimental & Clinical Cancer Research . 40(1): 382-382. Nº de citas: 5

    [doi:10.1186/s13046-021-02153-9]

  • Walter K, Rodriguez-Aznar E, Ferreira MSV, Frappart PO, Dittrich T, Tiwary K, Meessen S, Lerma L, Daiss N, Schulte LA, Najafova Z, Arnold F, Usachov V, Azoitei N, Erkan M, Lechel A, Brümmendorf TH, Seufferlein T, Kleger A, Tabarés E, Günes C, Johnsen SA, Beier F, Sainz B Jr, Hermann PC.

    Telomerase and Pluripotency Factors Jointly Regulate Stemness in Pancreatic Cancer Stem Cells

    Cancers . 13(13): . Nº de citas: 6

    [doi:10.3390/cancers13133145]

  • Ai, Jiaoyu, Wormann, Sonja M, Gorgulu, Kivanc, Vallespinos, Mireia, Zagorac, Sladjana, Alcala, Sonia, Wu, Nan, Kabacaoglu, Derya, Berninger, Alexandra, Navarro, Diego, Kaya-Aksoy, Ezgi, Ruess, Dietrich A, Ciecielski, Katrin J, Kowalska, Marlena, Demir, Ekin I, Ceyhan, Guralp O, Heid, Irina, Braren, Rickmer, Riemann, Marc, Schreiner, Sabrina, Hofmann, Samuel, Kutschke, Maria, Jastroch, Martin, Slotta-Huspenina, Julia, Muckenhuber, Alexander, Schlitter, Anna Melissa, Schmid, Roland M, Steiger, Katja, Diakopoulos, Kalliope N, Lesina, Marina, Sainz, Bruno Jr, Algul, Hana.

    BCL3 couples cancer stem cell enrichment with pancreatic cancer molecular subtypes.

    Gastroenterology . 161(1): 318. Nº de citas: 4

    [doi:10.1053/j.gastro.2021.03.051]

  • Conde, Elisa, Earl, Julie, Crespo-Toro, Lorena, Blanco-Agudo, Carolina, Ramos-Munoz, Edurne, Rodriguez-Serrano, E. Macarena, Martinez avila, Jose Carlos, Salinas-Munoz, Laura, Serrano-Huertas, Silvia, Ferreiro, Reyes, Rodriguez-Garrote, Mercedes, Sainz B Jr, Massuti, Bartomeu, Alfonso, Pilar Garcia, Benavides, Manuel, Aranda, Enrique, Garcia-Bermejo, Maria Laura, Carrato, Alfredo.

    Biomarkers Associated with Regorafenib First-Line Treatment Benefits in Metastatic Colorectal Cancer Patients: REFRAME Molecular Study

    Cancers . 13(7): . Nº de citas: 6

    [doi:10.3390/cancers13071710]

  • Earl, Julie, Barreto, Emma, Castillo, Maria E., Fuentes, Raquel, Rodriguez-Garrote, Mercedes, Ferreiro, Reyes, Reguera, Pablo, Munoz, Gloria, Garcia-Seisdedos, David, Lopez, Jorge Villalon, Sainz, Bruno, Malats, Nuria, Carrato, Alfredo.

    Somatic Mutation Profiling in the Liquid Biopsy and Clinical Analysis of Hereditary and Familial Pancreatic Cancer Cases Reveals KRAS Negativity and a Longer Overall Survival

    Cancers . 13(7): . Nº de citas: 4

    [doi:10.3390/cancers13071612]

  • Gout, Johann, Perkhofer, Lukas, Morawe, Mareen, Arnold, Frank, Ihle, Michaela, Biber, Stephanie, Lange, Sebastian, Roger, Elodie, Kraus, Johann M., Stifter, Katja, Hahn, Stephan A., Zamperone, Andrea, Engleitner, Thomas, Muller M, Walter, Karolin, Rodriguez-Aznar, Eva, Sainz B Jr, Hermann, Patrick C., Hessmann, Elisabeth, Muller S, Azoitei, Ninel, Lechel, Andre, Liebau, Stefan, Wagner, Martin, Simeone, Diane M., Kestler, Hans A., Seufferlein, Thomas, Wiesmuller L, Rad, Roland, Frappart, Pierre-Olivier, Kleger, Alexander.

    Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancer

    Gut . 70(4): 743-760. Nº de citas: 39

    [doi:10.1136/gutjnl-2019-319970]

  • Delle Cave, Donatella, Rizzo, Riccardo, Sainz B Jr, Gigli, Giuseppe, del Mercato, Loretta L., Lonardo, Enza.

    The Revolutionary Roads to Study Cell-Cell Interactions in 3D In Vitro Pancreatic Cancer Models

    Cancers . 13(4): . Nº de citas: 16

    [doi:10.3390/cancers13040930]

  • Courtois, Sarah, de Luxan-Delgado, Beatriz, Penin-Peyta, Laure, Royo-Garcia, Alba, Parejo-Alonso, Beatriz, Jagust, Petra, Alcala, Sonia, Rubiolo, Juan A., Sanchez, Laura, Sainz B Jr, Heeschen, Christopher, Sancho, Patricia.

    Inhibition of Mitochondrial Dynamics Preferentially Targets Pancreatic Cancer Cells with Enhanced Tumorigenic and Invasive Potential

    Cancers . 13(4): . Nº de citas: 22

    [doi:10.3390/cancers13040698]

  • López-Gil JC, Martin-Hijano, Laura, Hermann, Patrick C., Sainz B Jr.

    The CXCL12 Crossroads in Cancer Stem Cells and Their Niche

    Cancers . 13(3): . Nº de citas: 23

    [doi:10.3390/cancers13030469]

  • Alcala, Sonia, Mayoral-Varo, Victor, Ruiz-Canas, Laura, Lopez-Gil, Juan Carlos, Heeschen, Christopher, Martin-Perez, Jorge, Sainz B Jr.

    Targeting SRC Kinase Signaling in Pancreatic Cancer Stem Cells (vol 21, 7437, 2020)

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 21(23): .

    [doi:10.3390/ijms21239215]

  • Valle, Sandra, Alcala, Sonia, Martin-Hijano, Laura, Cabezas-Sainz, Pablo, Navarro, Diego, Munoz ER, Yuste, Lourdes, Tiwary, Kanishka, Walter, Karolin, Ruiz-Canas, Laura, Alonso-Nocelo, Marta, Rubiolo, Juan A., Gonzalez-Arnay, Emilio, Heeschen, Christopher, Garcia-Bermejo, Laura, Hermann, Patrick C., Sanchez, Laura, Sancho, Patricia, Fernandez-Moreno MA, Sainz B Jr.

    Exploiting oxidative phosphorylation to promote the stem and immunoevasive properties of pancreatic cancer stem cells

    NATURE COMMUNICATIONS . 11(1): 5265-5265. Nº de citas: 55

    [doi:10.1038/s41467-020-18954-z]

  • Alcala, Sonia, Mayoral-Varo, Victor, Ruiz-Canas, Laura, Lopez-Gil, Juan Carlos, Heeschen, Christopher, Martin-Perez, Jorge, Sainz B Jr.

    Targeting SRC Kinase Signaling in Pancreatic Cancer Stem Cells

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 21(20): . Nº de citas: 6

    [doi:10.3390/ijms21207437]