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Rheumatology

The group focuses its research projects on non-traumatic musculoskeletal diseases, mainly autoimmune diseases (Lupus, Scleroderma, Vasculitis, Inflammatory myopathies,...), and immune-mediated arthropathies (rheumatoid arthritis, psoriatic arthritis, spondyloarthritis,...). The group has mainly carried out clinical research studies (description of disease phenotypes, response to treatments) and, in recent years, basic research (histopathology, immunology, and genetics) has been added. Likewise, innovative projects have been developed (training of rheumatic patients, thermal imaging in arthritis, mobile devices for monitoring chronic diseases) for application to clinical practice. Four members of the group are doctors and 5 more are finishing their PhD. We have got updated records of disease groups, clinical situation and prescribed advanced (biological) treatments. We have got a collection of biological samples of all these autoimmune diseases in different stages of evolution and different treatments

Search for publications

Only original articles, editorials, guidelines.

  • Papa R, Rhee S, Delai P, Zhang K, Balcázar IB, Rethanavelu K, Fujiwara T, Mishima K, Tabarkiewicz J, Funck-Brentano T, Stander R, Bachiller-Corral J, Dahir KM, Eekhoff EMW, Hero M, Kuong E, Uemura N, Zhou M, Trotter DG, Gu J, Sanchez RJ, O'Donovan DÓ, Economides AN, Pordy R, Hirshberg B, Yancopoulos GD, Keen R.

    Efficacy and safety of garetosmab, an activin A-blocking antibody, in fibrodysplasia ossificans progressiva (OPTIMA): a randomised, double-blind, placebo-controlled, phase 3 trial.

    LANCET . 408(10564): 1583-1592.

    [doi:10.1016/S0140-6736(26)01599-0]

  • Loarce-Martos J, Tandaipan JL, Domínguez-Álvaro M, Carrión-Barberà I, Nuño-Nuño L, Martínez-Barrio J, Jovaní V, Romero-Bueno F, Ruiz-Lucea E, Tomero E, Trallero-Araguás E, Narváez J, Camins-Fàbregas J, Ruiz-Román A, de la Cámara-Fernández I, Riveros-Frutos A, Flores-Rodríguez VM, Sivera F, Merino-Argumanez C, Juan-Mas A, Altabás-González I, Martín-López M, Belzunegui-Otano JM, Carrasco-Cubero C, Freire-González M, Rúa-Figueroa I, Lozano-Rivas N, Suarez-Cuba JD, Turrión-Nieves AI, Ortega-Castro R, Alcocer P, Plasencia-Rodríguez C, Prado-Galbarro FJ, Cobo-Ibáñez T.

    Clinical characteristics of patients with antisynthetase syndrome and dermatomyositis-type skin involvement: Insights from the Myo-Spain registry.

    SEMINARS IN ARTHRITIS AND RHEUMATISM . 80: 153048-153048.

    [doi:10.1016/j.semarthrit.2026.153048]

  • Molina-Collada J, Plasencia-Rodriguez C, García-García V, Del Bosque I, Pavía-Pascual M, Villapún Burgoa B, Bourgeois-Avella C, Roig-Kim M, Narváez J, Hernández-Rodríguez I, Saez JC, Almeida C, García-Dorta A, Uriarte Itzazelaia E, Campos D, Dos-Santos R, Pérez-Pampín E, Jiménez Núñez FG, Fernández-Fernández E, Villalba A, Bou N, Pérez-García C, Rusinovich Lovgach O, Martínez Rodado A, González R, Cepas-Gutiérrez FJ, Olivas-Vergara O, Berrocal M, Molina N, González Mazón I, Toledano E, Tortosa-Cabañas M, Vellosillo González P, González Navarro P, Navarro-Compán V, Carmona L.

    Risk of new primary cancer, locoregional progression or metastasis associated with bDMARDs and tsDMARDs in patients with rheumatoid arthritis and prior cancer: insights from the ARCA registry.

    RMD Open . 12(3): .

    [doi:10.1136/rmdopen-2026-007113]

  • Macía-Villa C, Ferre-Sanfrancisco M, Huerta-Tajuelo I, Morell-Hita JL.

    Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Psoriatic Arthritis: A DAPSA-Based Validation Study.

    Mediterranean Journal of Rheumatology . 37(3): 514-518.

    [doi:10.31138/mjr.151205.ntl]

  • Molina-Collada J, Jiménez-Núñez FG, Ortiz-Márquez F, Rodríguez-Merlos P, Mayordomo L, Azabal-Perez C, Berrocal-Acedo M, Uson J, Garmendia E, Arostegui-Lavilla J, García-Vivar ML, Exposito-Molinero MR, Medina-Luezas J, Corral Bote A, Robustillo-Villarino M, Zúñiga-Vera A, Collado P, Alcalde-Villar M, Olivas-Vergara O, Estrada P, Navarro-Ángeles V, Blanco-Cáceres B, Ferre-Sanfrancisco M, Corrales-Martinez A, Corrales-Selaya C, Coronel L, de Agustin de Oro JJ, Miguelez-Sanchez JR, Peiteado D, Monjo-Henry I, Villalba A, Plasencia-Rodríguez C, Novella-Navarro M, Moragues C, Valencia Muntala L, Vicente-Rabaneda EF, Castañeda S, Bellón-Cano JM, Naredo E.

    Gender influence on ultrasound-assessed therapeutic response in rheumatoid arthritis: Insights from the GENder on UltraSound (GENUS) study.

    SEMINARS IN ARTHRITIS AND RHEUMATISM . 79: 152993-152993.

    [doi:10.1016/j.semarthrit.2026.152993]

  • Naredo E, Olivas-Vergara O, Borges PE, Recuero-Díaz S, Saraiva F, Martins-Martinho J, Costa F, Tenazinha C, Duarte-Monteiro AM, Melo AT, Guillén-Astete CA, Rodríguez-García A, Blanco-Cáceres B, Boteanu AL, Mera-Varela A, Pérez-Pampín E, Golán YL, Campos Fernández C, Fragío Gíl JJ, González Mazario R, Steiner M, Vergara-Dangond C, Paredes-Romero MB, Muñoz-Fernández S, Stoenoiu MS, Toukap AN, Durnez A, de Agustín de Oro JJ, Añez GA, Coronel L, Vicente-Rabaneda EF, Castañeda S, Llorente I, Padovano I, Gouze H, Leboime A, Breban M, Uson J, Villaverde-García V, Miguélez-Sánchez JR, Pérez García C, Meraz-Ostiz JA, Polino L, Finzel S, Kanne AM, Jandova I, Mediero A, Herencia C, Herrero-Beaumont G, Largo R.

    Response of ultrasound-assessed synovitis to baricitinib, in monotherapy and combined with methotrexate, compared with etanercept in rheumatoid arthritis: a randomised, international, multicentre trial.

    ANNALS OF THE RHEUMATIC DISEASES . 85(7): 1255-1267.

    [doi:10.1016/j.ard.2026.03.025]

  • Mohammad Reza Beigi D, Loarce-Martos J, Pellegrino G, Landini N, Panebianco V, de la Puente Bujidos C, García de Vicente A, Bisconti I, Di Ciommo FR, Cadar M, Arechavala Hita J, Truglia S, Bachiller-Corral J, Conti F, Riccieri V.

    Diagnostic performance of lung ultrasound for systemic sclerosis-associated interstitial lung disease: an international cross-sectional study from two tertiary care centers.

    CLINICAL RHEUMATOLOGY . 45(7): 4345-4353.

    [doi:10.1007/s10067-026-08191-y]

  • Macia-Villa C, Ferre-Sanfrancisco M, Ruiz-Bejerano AM, Morell-Hita JL.

    Distinct clinical profiles of methotrexate intolerance and hepatotoxicity in psoriatic arthritis.

    ARP Rheumatology . 5(3): 145-151.

  • Molina-Collada J, Cowley S, Kirby C, Kane D, Harkins P, Conway R, Castrejón I, Álvaro-Gracia JM, Ponte C, Monti S, Milanesi A, Conticini E, Placido F, El Miedany Y, Monjo-Henry I, Padoan R, Iorio L, Macchioni P, Salvarani C, Estrada P, Camacho Ó, Karalilova R, Blanco B, Moragues C, Bond M, Prieto Peña D, Sánchez J, de Agustín JJ, Santamaría PC, Mera Varela A, Calvo-Aranda E, Quick V, González Navarro P, Vellosillo González P, Dejaco C, de Miguel E.

    Prognostic value of quantifying vascular inflammation through ultrasound in patients with giant cell arteritis: the MAGiCUS study.

    RHEUMATOLOGY . 65(7): .

    [doi:10.1093/rheumatology/keag341]

  • Frade-Sosa B, Gómez-Puerta JA, Altabás-González I, Pego-Reigosa JM, Casafont-Solé I, Salman-Monte TC, Hernández-Martín A, Román-Ivorra JA, Piqueras-García M, Garrote-Corral S, Tomero E, de la Mata-Pinilla E, Calvo-Alén J, Martínez-Barrio J, Vidal-Montal P, Cortés-Hernández J, Ramos-Giráldez C, Novoa FJ, Torrente-Segarra V, Fragio-Gil J, Riancho-Zarrabeitia L, Rúa-Figueroa I.

    Does adding concomitant immunosuppressive therapy to belimumab provide additional benefits in SLE? Results From the BEL-Spain Registry.

    RHEUMATOLOGY . 65(6): .

    [doi:10.1093/rheumatology/keag076]

  • Martín-Gutiérrez A, Loricera J, Prieto-Peña D, Aldasoro V, Maiz O, de Miguel E, Galíndez-Agirregoikoa E, Ferraz-Amaro I, Castañeda S, Blanco R.

    Is there a window of opportunity in the treatment of giant cell arteritis with tocilizumab? Multicenter study of 471 patients.

    SEMINARS IN ARTHRITIS AND RHEUMATISM . 78: 152955-152955.

    [doi:10.1016/j.semarthrit.2026.152955]

  • Macia-Villa C, Fernandez-Velasco JI, Ferre-Sanfrancisco M, Mendoza-Bravo DA, Ruiz-Bejerano AM, Ferrez-Hernandez C, Morell-Hita JL.

    Exploring the phenotypic expression of HLA-B27 in psoriatic arthritis.

    CLINICAL RHEUMATOLOGY . 45(6): 3399-3404.

    [doi:10.1007/s10067-026-08144-5]

  • Harrison SR, Fragoulis GE, Michelena X, Macía-Villa C, Falzon L, Siebert S, Marzo-Ortega H, Sepriano A, Machado PM.

    Prevalence, outcomes, and predictive factors: a systematic literature review to inform the development of EULAR Points to Consider for the definition of Difficult-to-Manage and Treatment-Refractory psoriatic arthritis.

    Eular Rheumatology Open . 2(2): 100043-100043.

    [doi:10.1016/j.ero.2025.07.007]

  • Rusinovich-Lovgach O, Plaza Z, Andréu JL, Rosas J, Taboada VMM, Olive A, Almagro RM, Benavente BS, Font-Urgelles J, Garcia-Aparicio Á, Manrique-Arija S, Vadillo JAG, Lopez-Gonzalez R, Narváez J, Lozano MBR, Galisteo C, Martin JJG, Vela-Casasempere P, Bohorquez C, Erausquin C, Romero MBP, Riancho-Zarrabeitia L, Diaz SM, Altabás I, Heredia S, Moriano C, Cáceres BB, Estrada-Alarcón P, Judez E, Belzungui J, Loricera J, Ramos C, Alonso FS, Castro MF.

    Major adverse cardiovascular events in Sjögren's disease: incidence, associated factors, and impact on mortality in a prospective multicenter cohort.

    RHEUMATOLOGY INTERNATIONAL . 46(6): .

    [doi:10.1007/s00296-026-06138-9]

  • Villalobos-Sánchez L, Garrote-Corral S, Amil Casas I, Briones-Figueroa A, Morán-Alvarez P, García-Fernández A, Carrasco Sayalero Á, Tejada Velarde A, Lorente-Ros Á, Avendaño-Ortiz J, Camino López A, Jiménez Mena M, García-Villanueva MJ.

    Criterion and non-criteria antiphospholipid antibodies and acute coronary syndrome in the adult population under 55 years of age.

    MEDICINA CLINICA . 166(5): 107393-107393.

    [doi:10.1016/j.medcli.2026.107393]

  • Molina-Collada J, Bellón JM, Blanco-Cáceres B, Coronel L, de Agustín JJ, Estrada P, Garmendia Sánchez E, García Vivar ML, Olivas-Vergara O, Jiménez Núñez FG, Mayordomo L, Moragues C, Rebollo-Giménez AI, Uson J, Vicente-Rabaneda EF, Naredo E.

    Ultrasound evaluation of muscle quality in rheumatoid arthritis: a reliability study of the Spanish Ultrasound Muscle Assessment in Rheumatoid Arthritis (SpUMAR) score.

    ARTHRITIS RESEARCH & THERAPY . 28(1): .

    [doi:10.1186/s13075-026-03815-9]

  • Bachiller-Corral J, Martin-Martínez MA, Botello-Corzo D, Morell-Hita JL, Vázquez-Díaz M.

    Health literacy and control of inflammatory activity in patients with recent-onset rheumatoid arthritis.

    Rheumatology Advances in Practice . 10(2): .

    [doi:10.1093/rap/rkag049]

  • Macia-Villa C, Fernández-Velasco JI, Ferre-Sanfrancisco M, Mendoza-Bravo DA, Ruiz-Bejerano AM, Ferrez-Hernández C, Morell-Hita JL.

    HLA-Cw6 in Psoriatic Arthritis: Clinical Phenotype and Therapeutic Impact.

    JCR-JOURNAL OF CLINICAL RHEUMATOLOGY . 32(3): 79-84.

    [doi:10.1097/RHU.0000000000002322]