1. Home
  2. Research
  3. Research Groups
  4. Dendrimers for biomedical applications

Dendrimers for biomedical applications

Search for publications

Only original articles, editorials, guidelines.

  • Ortega, Miguel A., Fraile-Martinez, Oscar, Garcia-Montero, Cielo, Garcia-Gallego, Sandra, Sanchez-Trujillo, Lara, Torres-Carranza, Diego, Alvarez-Mon, Miguel Angel, Pekarek, Leonel, Garcia-Honduvilla, Natalio, Bujan, Julia, alvarez-Mon, Melchor, Asunsolo, Angel, De la Torre, Basilio.

    An integrative look at SARS-CoV-2 (Review)

    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE . 47(2): 415-434. Number of citations: 14

    [doi:10.3892/ijmm.2020.4828]

  • Mencia, Gabriel, Lozano-Cruz, Tania, Valiente, Mercedes, Jimenez, Jose Luis, de la Mata, Fco. Javier, Muñoz-Fernández MÁ, Cano, Jesus, Gillies, Elizabeth, Gomez, Rafael.

    Evaluation of pH-dependent amphiphilic carbosilane dendrons in micelle formation, drug loading and HIV-1 infection

    ORGANIC & BIOMOLECULAR CHEMISTRY . 18(47): 9639-9652. Number of citations: 3

    [doi:10.1039/d0ob01867h]

  • Hernandez-Corroto, Ester, Sanchez-Milla, Maria, Sanchez-Nieves, Javier, de la Mata FJ, Marina ML, García MC.

    Immobilization of thermolysin enzyme on dendronized silica supports. Evaluation of its feasibility on multiple protein hydrolysis cycles

    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES . 165: 2338-2348. Number of citations: 9

    [doi:10.1016/j.ijbiomac.2020.10.138]

  • Ciepluch, Karol, Skrzyniarz, Kinga, Zdanska, Justyna, Barrios-Gumiel, Andrea, Sanchez-Nieves, Javier, Javier de la Mata, F., Maciejewska, Barbara, Drulis-Kawa, Zuzanna, Bryszewska, Maria, Arabski, Michal.

    PEGylation of dendronized silver nanoparticles increases the binding affinity of antimicrobial proteins

    JOURNAL OF MOLECULAR LIQUIDS . 319: . Number of citations: 7

    [doi:10.1016/j.molliq.2020.114339]

  • Rodriguez-Prieto, Tamara, Hernandez-Breijo, Borja, Ortega, Miguel A., Gomez, Rafael, Sanchez-Nieves, Javier, Guijarro, Luis G..

    Dendritic Nanotheranostic for the Delivery of Infliximab: A Potential Carrier in Rheumatoid Arthritis Therapy

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 21(23): . Number of citations: 4

    [doi:10.3390/ijms21239101]

  • Sanz del Olmo, Natalia, Maroto-Diaz, Marta, Quintana, Sara, Gomez, Rafael, Holota, Marcin, Ionov, Maksim, Bryszewska, Maria, Carmena MJ, Ortega, Paula, Javier de la Mata, F..

    Heterofunctional ruthenium(II) carbosilane dendrons, a new class of dendritic molecules to fight against prostate cancer

    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY . 207: 112695-112695. Number of citations: 5

    [doi:10.1016/j.ejmech.2020.112695]

  • Ambrosio, Leanne, Argenziano, Monica, Cucci, Marie Angele, Grattarola, Margherita, de Graaf IAM, Dianzani, Chiara, Barrera, Giuseppina, Sanchez Nieves, Javier, Gomez, Rafael, Cavalli, Roberta, Pizzimenti, Stefania.

    Carbosilane Dendrimers Loaded with siRNA Targeting Nrf2 as a Tool to Overcome Cisplatin Chemoresistance in Bladder Cancer Cells

    ANTIOXIDANTS . 9(10): . Number of citations: 20

    [doi:10.3390/antiox9100993]

  • Rodriguez-Prieto, Tamara, Popp, Philipp F., Copa-Patino, Jose Luis, de la Mata, F. Javier, Cano, Jesus, Mascher, Thorsten, Gomez, Rafael.

    Silver (I) N-Heterocyclic Carbenes Carbosilane Dendritic Systems and Their Imidazolium-Terminated Analogues as Antibacterial Agents: Study of Their Mode of Action

    Pharmaceutics . 12(10): . Number of citations: 7

    [doi:10.3390/pharmaceutics12100968]

  • Heredero-Bermejo, Irene, Gomez-Casanova, Natalia, Quintana, Sara, Soliveri, Juan, de la Mata FJ, Perez-Serrano, Jorge, Sanchez-Nieves, Javier, Copa-Patino JL.

    In Vitro Activity of Carbosilane Cationic Dendritic Molecules on Prevention and Treatment of Candida Albicans Biofilms

    Pharmaceutics . 12(10): . Number of citations: 14

    [doi:10.3390/pharmaceutics12100918]

  • Apartsin, Evgeny, Knauer, Nadezhda, Arkhipova, Valeria, Pashkina, Ekaterina, Aktanova, Alina, Poletaeva, Julia, Sanchez-Nieves, Javier, de la Mata, Francisco Javier, Gomez, Rafael.

    pH-Sensitive Dendrimersomes of Hybrid Triazine-Carbosilane Dendritic Amphiphiles-Smart Vehicles for Drug Delivery

    NANOMATERIALS . 10(10): . Number of citations: 12

    [doi:10.3390/nano10101899]

  • Ortega, Miguel Angel, Guzman Merino, Alberto, Fraile-Martinez, Oscar, Recio-Ruiz, Judith, Pekarek, Leonel, G. Guijarro, Luis, Garcia-Honduvilla, Natalio, Alvarez-Mon, Melchor, Bujan, Julia, Garcia-Gallego, Sandra.

    Dendrimers and Dendritic Materials: From Laboratory to Medical Practice in Infectious Diseases

    Pharmaceutics . 12(9): . Number of citations: 28

    [doi:10.3390/pharmaceutics12090874]

  • Sanz del Olmo, Natalia, Holota, Marcin, Michlewska, Sylwia, Gomez, Rafael, Ortega, Paula, Ionov, Maksim, de la Mata, Francisco Javier, Bryszewska, Maria.

    Copper (II) Metallodendrimers Combined with Pro-Apoptotic siRNAs as a Promising Strategy Against Breast Cancer Cells

    Pharmaceutics . 12(8): . Number of citations: 17

    [doi:10.3390/pharmaceutics12080727]

  • Sanz del Olmo, Natalia, Peña González CE, Rojas JD, Gomez, Rafael, Ortega, Paula, Escarpa, Alberto, de la Mata FJ.

    Antioxidant and Antibacterial Properties of Carbosilane Dendrimers Functionalized with Polyphenolic Moieties

    Pharmaceutics . 12(8): . Number of citations: 15

    [doi:10.3390/pharmaceutics12080698]

  • Sanz del Olmo, Natalia, Bajo, Ana M., Ionov, Maksim, Garcia-Gallego, Sandra, Bryszewska, Maria, Gomez, Rafael, Ortega, Paula, de la Mata FJ.

    Cyclopentadienyl ruthenium(II) carbosilane metallodendrimers as a promising treatment against advanced prostate cancer

    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY . 199: 112414-112414. Number of citations: 10

    [doi:10.1016/j.ejmech.2020.112414]

  • Canonico, Barbara, Carloni, Riccardo, Sanz del Olmo, Natalia, Papa, Stefano, Nasoni, Maria Gemma, Fattori, Alberto, Cangiotti, Michela, de la Mata FJ, Ottaviani, Maria Francesca, Garcia-Gallego, Sandra.

    Fine-Tuning the Interaction and Therapeutic Effect of Cu(II) Carbosilane Metallodendrimers in Cancer Cells: An In Vitro Electron Paramagnetic Resonance Study

    MOLECULAR PHARMACEUTICS . 17(7): 2691-2702. Number of citations: 8

    [doi:10.1021/acs.molpharmaceut.0c00396]

  • Pedziwiatr-Werbicka, Elzbieta, Gorzkiewicz, Michal, Horodecka, Katarzyna, Abashkin, Viktar, Klajnert-Maculewicz, Barbara, Peña-González CE, Sanchez-Nieves, Javier, Gomez, Rafael, de la Mata FJ, Bryszewska, Maria.

    Silver Nanoparticles Surface-Modified with Carbosilane Dendrons as Carriers of Anticancer siRNA

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 21(13): . Number of citations: 14

    [doi:10.3390/ijms21134647]

  • Fernandez-Millan, Maria, Ortega, Paula, Cuenca, Tomas, Cano, Jesus, Mosquera, Marta E. G..

    Alkali-Metal Compounds with Bio-Based Ligands as Catalysts for Isoselective Lactide Polymerization: Influence of the Catalyst Aggregation on the Polymerization Control

    Organometallics . 39(12): 2278-2286. Number of citations: 13

    [doi:10.1021/acs.organomet.0c00237]

  • Lozano-Cruz, Tania, Alcarraz-Vizan, Gema, de la Mata FJ, de Pablo, Sara, Ortega, Paula, Duarte, Yorley, Bravo-Moraga, Felipe, González-Nilo FD, Novials, Anna, Gomez, Rafael.

    Cationic Carbosilane Dendritic Systems as Promising Anti-Amyloid Agents in Type 2 Diabetes

    CHEMISTRY-A EUROPEAN JOURNAL . 26(34): 7609-7621. Number of citations: 10

    [doi:10.1002/chem.202000091]