Dendrimers for biomedical applications

Group leaders

Francisco Javier de la Mata de la Mata

Sandra García Gallego

javier.delamata(ELIMINAR)@uah.es

Tlf.: +34 91 8854654

Principal Investigator

  • Rafael Gómez Ramírez
  • Matilde Alique Aguilar
  • Paula Ortega López

Collaborating Staff

  • Javier Sánchez-Nieves Fernández
  • Jesús Cano Sierra
  • Rafael Ramírez Chamond
  • Andrea Figuer Rubio
  • Laura Madrid González
  • Óscar Barrios Gumiel
  • Judith Recio Ruiz
  • Samuel Takvor Mena
  • Clara Gómez Serrano
  • Marcos Hernando Gozalo
  • Silvia Moreno Pinilla
  • Mercedes Gonzalez Rico
  • Natalia Sanz del Olmo
  • Inés Sobrino Gómez-Escalonilla
Imagen equipo

Group leaders

Francisco Javier de la Mata de la Mata

Sandra García Gallego

javier.delamata(ELIMINAR)@uah.es

Tlf.: +34 91 8854654

Principal Investigator

  • Rafael Gómez Ramírez
  • Matilde Alique Aguilar
  • Paula Ortega López

Collaborating Staff

  • Javier Sánchez-Nieves Fernández
  • Jesús Cano Sierra
  • Rafael Ramírez Chamond
  • Andrea Figuer Rubio
  • Laura Madrid González
  • Óscar Barrios Gumiel
  • Judith Recio Ruiz
  • Samuel Takvor Mena
  • Clara Gómez Serrano
  • Marcos Hernando Gozalo
  • Silvia Moreno Pinilla
  • Mercedes Gonzalez Rico
  • Natalia Sanz del Olmo
  • Inés Sobrino Gómez-Escalonilla

Strategic objectives

  • Synthesize a dendritic system platform capable of acting as a non-viral vector for drug and nucleic acid delivery.
  • Synthesize a dendritic system platform with intrinsic therapeutic activity against cancer and microbial diseases, or as an antiviral agent.
  • Establish collaborations with other groups within the Institute that may share common research interests.
  • Apply for European projects through and with IRYCIS.

Research lines

  • Synthesis of carbosilane-type dendritic systems for use as non-viral drug or nucleic acid vectors or as therapeutic agents.
  • Dendronization of molecules of pharmacological interest (drugs, peptides, antibodies, etc.).
  • Preparation of carbosilane metallodendritic systems for bioinorganic applications.
  • Dendronization of nanostructured materials for biomedical applications.
  • Synthesis of dendritic nanogels for drug encapsulation.
  • Application of dendritic systems against microbial resistance.
  • Application of dendritic systems against viruses, particularly HIV.
  • Applications of dendritic systems against cancer.
  • Applications of dendritic systems against neurodegenerative diseases.

Location

University of Alcalá

Department of Organic and Inorganic Chemistry
Faculty of Pharmacy

Link to UAH group

Keywords

Dendrimer, dendron, nanoparticle, hydrogels, carbosilane, biomedicine, cancer, HIV, microbial resistance