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Molecular Pathology of Cancer Group

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Only original articles, editorials, guidelines.

  • Bastien RR, Rodríguez-Lescure Á, Ebbert MT, Prat A, Munárriz B, Rowe L, Miller P, Ruiz-Borrego M, Anderson D, Lyons B, Álvarez I, Dowell T, Wall D, Seguí MÁ, Barley L, Boucher KM, Alba E, Pappas L, Davis CA, Aranda I, Fauron C, Stijleman IJ, Palacios J, Antón A, Carrasco E, Caballero R, Ellis MJ, Nielsen TO, Perou CM, Astill M, Bernard PS, Martín M.

    PAM50 Breast Cancer Subtyping by RT-qPCR and Concordance with Standard Clinical Molecular Markers

    BMC MEDICAL GENOMICS . 5: 44-44. Number of citations: 196

    [doi:10.1186/1755-8794-5-44]

  • Colas E, Pedrola N, Devis L, Ertekin T, Campoy I, Martínez E, Llauradó M, Rigau M, Olivan M, Garcia M, Cabrera S, Gil-Moreno A, Xercavins J, Castellvi J, Garcia A, Ramon y Cajal S, Moreno-Bueno G, Dolcet X, Alameda F, Palacios J, Prat J, Doll A, Matias-Guiu X, Abal M, Reventos J.

    The EMT signaling pathways in endometrial carcinoma

    CLINICAL & TRANSLATIONAL ONCOLOGY . 14(10): 715-720. Number of citations: 77

    [doi:10.1007/s12094-012-0866-3]

  • Leandro-García LJ, Leskelä S, Inglada-Pérez L, Landa I, de Cubas AA, Maliszewska A, Comino-Méndez I, Letón R, Gómez-Graña Á, Torres R, Ramírez JC, Álvarez S, Rivera J, Martínez C, Lozano ML, Cascón A, Robledo M, Rodríguez-Antona C.

    Hematologic beta-Tubulin VI Isoform Exhibits Genetic Variability That Influences Paclitaxel Toxicity

    CANCER RESEARCH . 72(18): 4744-4752. Number of citations: 22

    [doi:10.1158/0008-5472.CAN-11-2861]

  • Leandro-García LJ, Leskelä S, Jara C, Gréen H, Avall-Lundqvist E, Wheeler HE, Dolan ME, Inglada-Perez L, Maliszewska A, de Cubas AA, Comino-Méndez I, Mancikova V, Cascón A, Robledo M, Rodríguez-Antona C.

    Regulatory Polymorphisms in beta-Tubulin IIa Are Associated with Paclitaxel-Induced Peripheral Neuropathy

    CLINICAL CANCER RESEARCH . 18(16): 4441-4448. Number of citations: 53

    [doi:10.1158/1078-0432.CCR-12-1221]

  • Llauradó M, Ruiz A, Majem B, Ertekin T, Colás E, Pedrola N, Devis L, Rigau M, Sequeiros T, Montes M, Garcia M, Cabrera S, Gil-Moreno A, Xercavins J, Castellví J, Garcia A, Ramón y Cajal S, Moreno G, Alameda F, Vázquez-Levin M, Palacios J, Prat J, Doll A, Matías-Guiu X, Abal M, Reventós J.

    Molecular bases of endometrial cancer: New roles for new actors in the diagnosis and the therapy of the disease

    MOLECULAR AND CELLULAR ENDOCRINOLOGY . 358(2, SI): 244-255. Number of citations: 40

    [doi:10.1016/j.mce.2011.10.003]

  • Sánchez-Rovira P, Antón A, Barnadas A, Velasco A, Lomas M, Rodríguez-Pinilla M, Ramírez JL, Ramírez C, Ríos MJ, Castellá E, García-Andrade C, San Antonio B, Carrasco E, Palacios JL.

    Classical markers like ER and ki-67, but also survivin and pERK, could be involved in the pathological response to gemcitabine, adriamycin and paclitaxel (GAT) in locally advanced breast cancer patients: results from the GEICAM/2002-01 phase II study

    CLINICAL & TRANSLATIONAL ONCOLOGY . 14(6): 430-436. Number of citations: 10

    [doi:10.1007/s12094-012-0820-4]

  • Hernandez L, Wilkerson PM, Lambros MB, Campion-Flora A, Rodrigues DN, Gauthier A, Cabral C, Pawar V, Mackay A, A'hern R, Marchiò C, Palacios J, Natrajan R, Weigelt B, Reis-Filho JS.

    Genomic and mutational profiling of ductal carcinomas in situ and matched adjacent invasive breast cancers reveals intra-tumour genetic heterogeneity and clonal selection

    JOURNAL OF PATHOLOGY . 227(1): 42-52. Number of citations: 111

    [doi:10.1002/path.3990]

  • Durán-Prado M, Gahete MD, Hergueta-Redondo M, Martínez-Fuentes AJ, Córdoba-Chacón J, Palacios J, Gracia-Navarro F, Moreno-Bueno G, Malagón MM, Luque RM, Castaño JP.

    The new truncated somatostatin receptor variant sst5TMD4 is associated to poor prognosis in breast cancer and increases malignancy in MCF-7 cells

    Oncogene . 31(16): 2049-2061. Number of citations: 54

    [doi:10.1038/onc.2011.389]

  • Albanell J, González A, Ruiz-Borrego M, Alba E, García-Saenz JA, Corominas JM, Burgues O, Furio V, Rojo A, Palacios J, Bermejo B, Martínez-García M, Limon ML, Muñoz AS, Martín M, Tusquets I, Rojo F, Colomer R, Faull I, Lluch A.

    Prospective transGEICAM study of the impact of the 21-gene Recurrence Score assay and traditional clinicopathological factors on adjuvant clinical decision making in women with estrogen receptor-positive (ER plus ) node-negative breast cancer

    Annals of oncology : official journal of the European Society for Medical Oncology . 23(3): 625-631. Number of citations: 93

    [doi:10.1093/annonc/mdr278]

  • Santacana M, Yeramian A, Velasco A, Bergada L, Gatius S, García V, Azueta A, Palacios J, Dolcet X, Oliva E, Matias-Guiu X.

    Immunohistochemical features of post-radiation vaginal recurrences of endometrioid carcinomas of the endometrium: role for proteins involved in resistance to apoptosis and hypoxia

    Histopathology . 60(3): 460-471. Number of citations: 12

    [doi:10.1111/j.1365-2559.2011.04106.x]

  • Moch H, Blank PR, Dietel M, Elmberger G, Kerr KM, Palacios J, Penault-Llorca F, Rossi G, Szucs TD.

    Personalized cancer medicine and the future of pathology

    VIRCHOWS ARCHIV . 460(1): 3-8. Number of citations: 27

    [doi:10.1007/s00428-011-1179-6]

  • Natrajan R, Mackay A, Wilkerson PM, Lambros MB, Wetterskog D, Arnedos M, Shiu KK, Geyer FC, Langerød A, Kreike B, Reyal F, Horlings HM, van de Vijver MJ, Palacios J, Weigelt B, Reis-Filho JS.

    Functional characterization of the 19q12 amplicon in grade III breast cancers

    BREAST CANCER RESEARCH . 14(2): . Number of citations: 51

    [doi:10.1186/bcr3154]

  • Wetterskog D, Lopez-Garcia MA, Lambros MB, A'Hern R, Geyer FC, Milanezi F, Cabral MC, Natrajan R, Gauthier A, Shiu KK, Orr N, Shousha S, Gatalica Z, Mackay A, Palacios J, Reis-Filho JS, Weigelt B.

    Adenoid cystic carcinomas constitute a genomically distinct subgroup of triple-negative and basal-like breast cancers

    JOURNAL OF PATHOLOGY . 226(1): 84-96. Number of citations: 105

    [doi:10.1002/path.2974]

  • Santón A, Cristóbal E, Aparicio M, Royuela A, Villar LM, Alvarez-Cermeño JC.

    High frequency of co-infection by Epstein-Barr virus types 1 and 2 in patients with multiple sclerosis

    MULTIPLE SCLEROSIS JOURNAL . 17(11): 1295-1300. Number of citations: 22

    [doi:10.1177/1352458511411063]

  • Gómez-Martín C, Concha A, Corominas JM, García-Caballero T, García-García E, Iglesias M, López JA, Ramón y Cajal S, Rojo F, Palacios J, Vera-Sempere F, Aranda E, Colomer R, García-Alfonso P, Garrido P, Rivera F, López-Ríos F.

    Consensus of the Spanish Society of Medical Oncology (SEOM) and Spanish Society of Pathology (SEAP) for HER2 testing in gastric carcinoma

    CLINICAL & TRANSLATIONAL ONCOLOGY . 13(9): 636-651. Number of citations: 15

    [doi:10.1007/s12094-011-0709-7]

  • Doníz-Padilla L, Paniagua AE, Sandoval-Correa P, Monsiváis-Urenda A, Leskela S, Marazuela M, González-Amaro R.

    Analysis of expression and function of the inhibitory receptor ILT2 in lymphocytes from patients with autoimmune thyroid disease

    EUROPEAN JOURNAL OF ENDOCRINOLOGY . 165(1): 129-136. Number of citations: 9

    [doi:10.1530/EJE-11-0109]

  • Santón A, García-Cosío M, Cristóbal E, Pascual A, Muriel A, García-Laraña J.

    Expression of heat shock proteins in classical Hodgkin lymphoma: correlation with apoptotic pathways and prognostic significance

    Histopathology . 58(7): 1072-1080. Number of citations: 10

    [doi:10.1111/j.1365-2559.2011.03803.x]

  • Leskelä S, Jara C, Leandro-García LJ, Martínez A, García-Donas J, Hernando S, Hurtado A, Vicario JC, Montero-Conde C, Landa I, López-Jiménez E, Cascón A, Milne RL, Robledo M, Rodríguez-Antona C.

    Polymorphisms in cytochromes P450 2C8 and 3A5 are associated with paclitaxel neurotoxicity

    PHARMACOGENOMICS JOURNAL . 11(2): 121-129. Number of citations: 89

    [doi:10.1038/tpj.2010.13]