Neuroproteins-stroke

2023 Activity indicators

6 national public projects: ISCIII, MINECO
11 clinical led trials
4 competitive HR contracts.
24 publications
IF: 141.52
Q1 publications: 13 (54%)
D1 publications: 6 (25 %)
Public agency evaluators: 2 PI
6 active patent families::
- 1 patent family extended internationally in 11 countries protecting the use of steronitrones in neurodegenerative diseases (PCT/ ES2014/070421)
- 1 granted patent (P201131338) protecting quinolinitrones for the same purpose at national level
- 1 patent applied for to protect new quinolylnitrone compounds PCT/EP2019/077525, extended in the US and EU
- 1 new patent for new steronitrone compounds with European priority application EP20382158 and PCT/ EP2021/055653, extended in US and EU
- 1 application for a nitrone-like compound in stroke with European application EP22382680
- 1 application for a nitrone-like compound in deafness with European application EP22382706.4 and PCT/EP2023/070340

Milestones

Publication of potential drugs for the treatment of ischemic stroke. Escobar A, Martínez E, Masjuan J, Alcázar A. Development of Pharmacological Strategies with Therapeutic Potential in Ischemic Stroke. Antioxidants (Basel). 2023;12(12). DOI:10.3390/antiox12122102. PMID: 38136221.
Publication of a new mechanism of damage in cerebral ischemia. Álvarez I, Muñoz MD, Hernández JM, Solís JM. Identification of Non-excitatory Amino Acids and Transporters Mediating the Irreversible Synaptic Silencing After Hypoxia. TRANSL STROKE RES. 2023;DOI:10.1007/s12975-023-01192-y. PMID: 37755645.
Participation in a clinical genetic study of the relationship between Covid-19 and stroke. Llucià-Carol L, Muiño E, Cullell N, Cárcel-Márquez J, Lledós M, Gallego-Fabrega C, Martin-Campos J, Martí-Fàbregas J, Aguilera-Simón A, Planas AM, DeDiego ML, de Felipe Mimbrera A, Masjuan J, García-Madrona S, Segura T, González-Villar E, Serrano-Heras G, Domínguez Mayoral A, Menéndez-Valladares P, Montaner J, Migeotte I, Rahmouni S, Darcis G, Bernardo D, Rojo S, Schulte EC, Protzer U, Fricke L, Winter C, Niemi MEK, Cordioli M, Delgado P, Fernández-Cadenas I. Genetic Architecture of Ischaemic Strokes after COVID-19 Shows Similarities with Large Vessel Strokes. Int J Mol Sci. 2023 Aug 30;24(17):13452. DOI: 10.3390/ijms24171313452. PMID: 37686257.
Publicación sobre una nueva monitorización funcional. Martín G, Cabañes L, López JR, Mateo RC, Reyes A, Gandarias C, Regidor I. Utilidad del H-Reflex para la Monitorización Intraoperatoria de Aneurismas Toracoabdominales. J Clin Neurophysiol. 2023 26 de mayo. DOI: 10.1097/WNP.0000000000001016. PMID: 37255237.
Concesión Patente Europea EP3863632A1 «Quinolylnitrones for the treatment and prevention of a cerebral stroke or ischaemia» y solicitud de Patente PCT número PCT/EP2023/070340 «Quinolyl-nitrone derivatives for use in the prevention and/or treatment of hearing loss». Entidades Titulares: FIBioHRC y CSIC.

Bibliometrics

	Articles	Accum. FI	Mean IF	Articles Q1 or Q2	% in Q1 or Q2	Articles D1	% in D1
2019	20	153.38	9.59	16	80	4	20
2020	22	68.50	3.61	11	50	4	18
2021	35	178.39	5.20	20	57	7	20
2022	25	426.05	18.52	19	76	6	24
2023	24	141.52	7.06	17	71	6	25
	126	967.86	9.23	83	66	27	21