Neuroproteins-stroke
Group leader
Alberto Alcázar González
alberto.alcazar(ELIMINAR)@hrc.es
Principal Investigator
- Jaime Masjuán Vallejo
- Jesús Miguel Hernández Guijo
Collaborating Staff
- Alicia de Felipe Mimbrera
- Mercedes Gómez-Calcerrada Iniesta
- Emma Martínez Alonso
- Ignacio Regidor Bailly-Bailliere
- María Consuelo Matute Lozano
- Rocío Vera Lechuga
- Antonio Cruz Culebras
- Alejandro Escobar Peso
- Lorena Peracho Benito
- Sebastián García Madrona
- Marcel Roca Sanz
- Marta del Álamo de Pedro
Principal Investigator
- Jaime Masjuán Vallejo
- Jesús Miguel Hernández Guijo
Collaborating Staff
- Alicia de Felipe Mimbrera
- Mercedes Gómez-Calcerrada Iniesta
- Emma Martínez Alonso
- Ignacio Regidor Bailly-Bailliere
- María Consuelo Matute Lozano
- Rocío Vera Lechuga
- Antonio Cruz Culebras
- Alejandro Escobar Peso
- Lorena Peracho Benito
- Sebastián García Madrona
- Marcel Roca Sanz
- Marta del Álamo de Pedro
Strategic objectives
- Advance in the understanding of cerebral ischemia pathology.
- Development of pharmacological strategies with therapeutic potential to improve functional recovery after ischemic stroke.
- Treatment of strokes in the acute phase.
Research lines
Lines of clinical research:
- Secondary prevention in stroke
- Reperfusion treatments in cerebral infarction. Use of neuroprotective drugs.
- Cerebrovascular complications in patients on antivitamin K therapy.
- Recurrent cardioembolic strokes. New indications for atrial appendage closure. Carotid filters.
- Coagulation factor XI inhibitors in non-cardioembolic strokes.
- Analysis of thrombi removed by mechanical thrombectomy.
Lines of experimental research:
- Mechanisms of death and neuroprotection in cerebral ischemia.
- Identification of proteins involved in neurorepair after cerebral ischemia. Clinical experimental study.
- Exploration of new neuroprotective drugs for cerebral ischemia.
- Study of non-excitatory amino acid transporters as new molecular targets in brain damage caused by ischemia.
Location
Stroke Unit
Neurology Service, 5D
Neuroproteins and Ischemia Laboratory
Dept. Research -1D
Ramón y Cajal University Hospital
Department of Pharmacology. School of Medicine. UAM
Keywords
stroke, neuroprotection, brain ischemia, experimental models, therapeutic targets, reperfusion treatments, drug trial, molecular mechanisms, neuronal death